Best Operating Grants for Nonprofits in Massachusetts

The FY26 Autism Research Program's Idea Development Award from the US DOD aims to support groundbreaking research that improves outcomes for Autistic individuals. This award encourages innovative, high-risk projects that can lead to significant advancements in autism research. Applications must address specific areas of interest or justify the importance of the research problem. A unique Partnering Principal Investigator option allows two researchers to collaborate on a single project, enhancing the potential for impactful discoveries.

The Athene Charitable Foundation focuses on corporate social responsibility through community involvement, aiming to create positive social impacts in education, health, human services, and the environment. Their initiatives include partnerships, employee volunteering, and donations aligned with their mission. They prioritize organizations that support diversity and inclusion while ensuring compliance with their non-discrimination policies. Eligible entities must be registered 501(c)(3) organizations or equivalent, enhancing community welfare where Athene employees live and work.

The John and Barbara Wolcott Memorial Scholarship, offered by the San Luis Obispo County Community Foundation, supports public high school students in San Luis Obispo County pursuing post-secondary education. This scholarship recognizes students demonstrating academic potential, motivation, and a strong work ethic. It aims to help deserving individuals achieve their educational and career aspirations, contributing to a brighter future for the community. Applications for the 2025-2026 academic year are now open.

The John and Yvonne Hsu Edmisten Scholarship honors Allan Voight M.D. and supports graduating seniors from Lucia Mar Unified School District or graduate students with a minimum GPA of 2.9. Offered by the San Luis Obispo County Community Foundation, this scholarship aims to empower local students to achieve their educational and career aspirations. Applications for the 2025-2026 academic year are now open, inviting eligible students to take advantage of this opportunity.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Emily & Frank Smiddy Scholarship

This scholarship has been made possible by the generosity of Emily & Frank Smiddy who established the Emily & Frank Smiddy Scholarship Fund of the Community Foundation for Mason County.

Frank Smiddy, former owner of ProAct Environmental Services located in Ludington, has always had a passion for STEM-related learning and wants to give back to the community where he owns his business. He and his wife, Emily, wanted to leave a legacy of students going into this field the best chance possible to get their college education with as little debt as possible, so they established the Emily & Frank Smiddy Scholarship Fund. It is their hope that students receiving this scholarship will be motivated, when they are financially able, to give back to the community to help others see success.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Drs. Ruth & John Carney & Irene Carney Kendrick Memorial Scholarship

This scholarship has been made possible by the generosity of Dr. John Carney, who established the Drs. Ruth & John Carney & Irene Carney Kendrick Memorial Scholarship of the Community Foundation for Mason County.

The Carney’s love of Ludington ran deep, and they served the Ludington community through their family medical practice for over 42 years. Dr. Carney valued education and wanted to help others achieve their dreams. John’s encouraging spirit lives on through this scholarship, established in memory of his first wife and their late daughter, to create opportunities for adult students, students pursuing postgraduate degrees, or those facing barriers to getting a college degree.

Arnold Ventures

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change. To advance this mission, we invest in rigorous research to strengthen the evidence base on what works to improve outcomes for individuals, families, and communities, and to inform policy and practice at scale.

AV’s Higher Education team seeks to fund rigorous, causal research on programs, policies, and practices that improve student outcomes and deliver stronger returns on investment for students and taxpayers. Our work focuses on strengthening the evidence base on effective student success models and aligning policy and funding incentives to support their adoption and scale.

Causal Research to Improve Outcomes for Part-Time Students

Purpose of the RFP

This RFP seeks to fund rigorous causal research that builds the evidence base on effective programs and policies for part-time students and identifies scalable, cost-effective approaches to improve completion and labor market outcomes. Findings should generate actionable insights to inform institutional practice, system-level decision making, and state policy, with the goal of improving outcomes and maximizing return on investment for students and taxpayers.

Population of Interest

Because enrollment intensity is fluid, proposals do not need to limit eligibility to students who are enrolled part-time at baseline. Instead, studies should focus on interventions that primarily serve or are expected to meaningfully impact students who are more likely to enroll part-time, including:

• Adult learners (age 25+)
• Student parents and caregivers
• Working adults

Interventions may serve mixed-enrollment populations, so long as the proposed study is clearly designed to improve outcomes for these populations.

The NASPGHAN Foundation/APGNN Susan Moyer Research Grant supports impactful research and quality improvement initiatives aimed at enhancing nursing care for children with gastrointestinal and nutritional disorders. Grants ranging from $500 to $5000 are available for eligible Registered Nurses who are APGNN members. Awardees must present their findings at the NASPGHAN Annual Meeting and adhere to specific funding guidelines, including IRB approval and acknowledgment of support in publications.

The Open Ocean Research Grant Program, funded by Global Fishing Watch Inc, aims to enhance ocean governance through data sharing on human activity at sea. It invites researchers to improve technologies for better governance, offering up to $10,000 for individuals and $20,000 for small groups. This initiative strengthens the community of practice and optimizes Global Fishing Watch datasets to maximize their impact on ocean conservation efforts.

The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) aims to create a secure, scalable cloud platform for genetic data related to Alzheimer’s disease. This initiative will enhance data accessibility, promote interoperability, and support rigorous research practices. By facilitating collaboration and providing robust analytical tools, the platform will maximize the scientific impact of AD/ADRD research, aligning with NIH goals for transparent and reproducible science, while addressing recommendations for broad access to high-value datasets.

The Peer Education Grant, offered by the Organization for Autism Research, aims to enhance autism acceptance among children by providing educational resources and funding for initiatives. Grants of up to $10,000 support school-wide projects, with smaller grants available for other activities. Eligible applicants include educators and community organization leaders focused on autism awareness, particularly in low-income areas. This initiative fosters inclusive relationships and understanding between children and their autistic peers.

Joseph P. Siegferth Sr. and Family Fund

Established by Joseph P. Siegferth Jr. in memory of his father to provide scholarships to graduating high school seniors majoring in elementary education, K-12 physical education, sports management or logistics.

Amount:

• $1,000

Number of awards:

• Varies

Renewal:

• No

The MBF Small Grants Program supports conservation projects for monarch butterflies and their habitats, primarily in Mexico. It aims to fund initiatives focusing on habitat conservation, scientific research, education, and sustainable development. Grants are primarily awarded to Mexican organizations and individuals, with a preference for those with relevant experience. Projects should enhance local livelihoods and promote environmental awareness within the Monarch Butterfly Biosphere Reserve.

The Jacques Pepin Foundation (JPF) is dedicated to advancing culinary arts education by supporting community kitchens that provide culinary training to individuals facing employment barriers. Grants of up to $10,000 are available for nonprofits to enhance their culinary programs, including operating costs and facility improvements. Eligibility extends to organizations funded in prior cycles, those that applied but were not funded, and newcomers to JPF funding. This initiative aims to empower underserved communities through culinary skills.

MetroWest Health Foundation

The MetroWest Health Foundation is an independent health philanthropy whose mission is to improve the health status of the community, its individuals, and families through informed and innovative leadership.

The foundation meets the health needs of our region's residents by supporting community-based and community driven programs. We encourage and foster leadership on critical health issues. We are a grantmaker, convener and facilitator, working to provide resources, information, ideas and advocacy for community change. Since its inception in 1999, the foundation has provided more than $50 million in financial support that helps residents and their families lead healthier lives.

MetroWest Health Foundation: Nursing Scholarship

Scholarships are provided to students who are residents of one of the 25 towns in our MetroWest service area. Students must be accepted into an eligible nursing program at an accredited academic institution.

Tuition scholarships are awarded for a maximum of up to $4,000 per academic year. Students can receive a maximum of 4 scholarships. Applicants are eligible to reapply on an annual basis.

The Bernie Smillie Memorial Scholarship was established in 2010, in memory of Freeland resident and business owner Bernie Smillie. Bernie passed away in 2000, due to complications from a lung transplant he had received in 1994. In 2005, family and friends of Bernie established the Bernie Smillie Memorial Golf Outing. Proceeds of this outing has helped to promote organ donor support and awareness and establish this scholarship fund.

Bernie Smillie Memorial Scholarship - Michigan Resident

Evaluation Criteria

• Financial need (20)
• Work experience (20)
• Overall involvement at work, school and community activities (20)
• Career goals as demonstrated in essay (20)
• Letters of recommendation

Women of Colors Scholarship

Women of Colors (WOC) was founded in 1993 by a group of women that believed it would take a cooperative effort of women of all nationalities, ages and socioeconomic status to address issues plaguing the Saginaw Community. The founders believed that women should take a more active role in addressing issues of crime, blight and poverty. WOC began by providing support, community outreach services and facilitating discussions within the community. WOC’s mission promotes multi-cultural diversity and enhances community relations in Saginaw County by performing community service, mentoring youth, and collaborating with other organizations.

The Women of Colors Scholarship will be awarded each year to a Great Empowering Motivational Sessions (GEMS) member that is an area high school senior actively involved in efforts to empower young women and in activities that address issues affecting young women in the Saginaw Community. If no GEMS members are high school seniors, applications will be accepted from non-GEMS applicants.

Joseph L. Ruby Student Scholarship Fund

Established in honor of former Direction Home Akron Canton President and CEO Joseph Ruby to award scholarships to students enrolled in gerontology, social work, nursing or a related health care program.

Amount:

• $5,000 or more

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application.

The Ryder Sroufe Memorial Scholarship, established by the Community Foundation of Whitley County in 2025, honors the legacy of Ryder Carl Sroufe. This scholarship supports young individuals who embody enthusiasm, humility, and compassion, reflecting Ryder's spirit of kindness and service. It aims to empower the next generation of leaders and helpers, ensuring that Ryder's values of hard work and community commitment continue to thrive. Eligible students are recognized for their efforts to strengthen their communities.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Terence J. Centner Agricultural and Environmental 4-H Scholarship

The Terence J. Centner Agricultural and Environmental 4-H Scholarship benefits student that participated in 4-H for a minimum of 3 years and completed an outstanding agricultural or environmental project.

This fund is established in memory of Harry E. and Mary Ellen Centner to honor their dedication and hard work on their family farm in the Town of Dunkirk and their leadership activities in the Chautauqua County 4-H Program.

The Incubator Grant, offered by the Society of Interventional Radiology Foundation, supports projects that enhance interventional radiology through clinical research. Eligible applicants must be SIR members and hold relevant degrees. The grant provides funding up to $25,000 for one year, specifically for developing clinical study protocols and proposals. This initiative emphasizes inclusivity and encourages innovative approaches in patient care, aligning with the foundation's mission to advance the specialty and improve patient outcomes.

The National Institutes on Deafness and Other Communication Disorders (NIDCD) aims to support a collaborative network, the NIDCD National Human Ear Resource Network. This initiative provides essential resources for researchers focusing on auditory and vestibular disorders through the procurement and preparation of human ear tissues. The network enhances biomedical research by improving tissue preservation techniques, sharing digitized images, and offering specialized training for handling post-mortem human temporal bones.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Thomas Thompson Family Scholarship

This scholarship has been made possible by the generosity of Thomas Thompson, who established the Thomas Thompson Family Scholarship of the Community Foundation for Mason County.

Thomas Thompson, a Ludington Area Schools alumnus, created a scholarship fund in his family's name because many of his family members have received scholarships over the years. Because of his first-hand knowledge of the difference financial support for college meant, he wanted to share the good feeling of making a difference for future generations. "It is one of the things I wanted to do in my life," said Thomas.

The Kidney Precision Medicine Project Central Hub, funded by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), aims to enhance our understanding of Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). This initiative, which began in FY2017, focuses on ethically collecting and analyzing kidney biopsy tissues to uncover molecular pathways. The project was expanded in FY2022 to improve participant recruitment and tissue analysis, driving forward research in kidney health.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is extending the Kidney Precision Medicine Project (KPMP) for five years to enhance participant recruitment and tissue interrogation. This initiative aims to discover novel molecular pathways associated with Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). The renewed funding will support robust longitudinal follow-ups for existing enrollees and facilitate the enrollment of new participants, ensuring comprehensive data analysis and collaboration within the research community.

The Kidney Precision Medicine Project (KPMP), funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), aims to enhance research on Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). Launched in 2017, this initiative focuses on ethical collection and analysis of human kidney tissue to uncover new molecular pathways. With expanded participant recruitment efforts beginning in 2022, the KPMP seeks to advance our understanding of kidney-related health issues.

Patrick Caroselli Scholarship

To provide financial assistance for college to high school seniors in Monroe County whose parents immigrated to the United States and attained citizenship.

Number and Size of Awards

Number of recipients and award amounts vary; award amount may be split between two or more recipients. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters. Average award $5,000; not to exceed the cost of tuition.

Allowed Use of Award

Awards must be used for costs related to enrollment in a higher education program, prioritizing tuition fees.