Best Seed Grants for Nonprofits in Massachusetts

The GoodRx Helps Community Catalyst Grants support community-led nonprofits dedicated to enhancing health and well-being for under-resourced groups. This funding aims to improve healthcare access, education, and essential services, addressing systemic barriers faced by these communities. Eligible organizations must demonstrate a commitment to community empowerment and possess a minimum annual operating budget of $250K. This initiative underscores the importance of fostering sustainable health improvements through targeted, inclusive support.

The Olney Medal, established in 1944 by the American Association of Textile Chemists and Colorists (AATCC), honors exceptional achievements in textile chemistry and related fields. It recognizes significant contributions to the development of chemical processes and agents in textile manufacturing. Open to all AATCC members for nominations, the award emphasizes the importance of innovation and public recognition in advancing textile sciences, a legacy of its founder, Dr. Louis Atwell Olney.

The All of Us Research Program seeks to advance its mission by enabling access to biospecimens stored in the All of Us supported Biobank for researchers to conduct assays to evaluate associations between biomarkers and chronic diseases and add data to the All of Us resource for broad use by researchers. Biomarker analysis includes, but is not limited to, biomarker discovery; biomarker validation; novel disease stratification; and multiomics integration for disease risk, diagnosis, and prognosis, in support of advancing precision medicine. The All of Us Research Program is a historic effort to enroll 1 million participants who share data to accelerate research and medical breakthroughs, and enable individualized prevention, treatment, and care. Researchers use data from the program to learn more about how individual differences in lifestyle, environment, and genetics can influence health and disease.Grant authorities that allow the All of Us Research Program to forecast this opportunity are as follows: 42 USC 241 and 284.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The Felicia Rose Grant Program supports animal welfare nonprofits in Massachusetts and Southern New Hampshire, focusing on strengthening the human-animal bond and providing care for animals in need. With $120,000 awarded annually, eligible 501(c)(3) organizations can apply for grants up to $20,000 for operating expenses. This initiative honors Felicia Rose, a therapy dog who exemplifies the program's mission. Organizations must meet specific criteria, including location and experience, to qualify for funding.

The Eleanor Campbell Charitable Fund offers competitive scholarships to high school seniors and current college students from the Deering, Hillsborough, and Weare areas. With a history of over $900,000 awarded, the fund emphasizes academic achievement, financial need, and community involvement. Scholarships are available for full-time post-secondary education, with the potential for renewal based on continued eligibility. Announcements of winners occur during high school graduation ceremonies, ensuring recognition of their hard work and dedication.

The Guru Krupa Foundation Grant supports charitable causes in social, educational, and religious/cultural areas, rooted in Hindu values. The foundation prioritizes projects that aid the underprivileged, enhance education, and preserve cultural heritage, particularly in India and the US. Eligible organizations must be tax-exempt and demonstrate a commitment to effective accounting practices. The foundation seeks specific projects with measurable outcomes, focusing on direct funding for programs rather than administrative costs.

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Cherokee Nation Allied Health Scholarship

The purpose of the Cherokee Nation Allied Health Scholarship is to provide financial assistance to Cherokee Nation citizens pursuing college degrees in health care fields to support their readiness to contribute to and grow within the Cherokee Nation reservation labor market. This scholarship is competitive and subject to availability of funding.

The foundation also offers a Nursing Scholarship and if funding allows, scholarships will be available for degrees in health fields other than nursing to meet any current workforce need in the Cherokee Nation Health Services department.

Alpha Omega Alpha Honor Medical Society

Alpha Omega Alpha, founded in 1902, is the national medical honor society. Its mission is:

• Alpha Omega Alpha — dedicated to the belief that in the profession of medicine we will improve care for all by:
• recognizing high educational achievement;
• honoring gifted teaching;
• encouraging the development of leaders in academia and the community;
• supporting the ideals of humanism; and
• promoting service to others.

Helen H. Glaser Student Essay Award

To encourage medical students to write scholarly essays relevant to medicine. Winning essays will be published in an issue of The Pharos.

Only one entry may be submitted per student.

Requirements

• Essays must be written while the student is in medical school, must be the work of a single author, and must be an original work. The essay must not be offered to, or published by, any other journal or entered in any other contest prior to submission or during, the AΩA selection process.
• The essay must be related to medicine.
• Essays should not be fictional or written in first person, but academic/scientific in theme.
• The essay must not exceed 15 double-spaced pages of 12-point type with minimum 1-inch margins, exclusive of reference listing. The author’s name and essay title must be on each page, and all pages must be numbered.
• Unique references, numbered consecutively, should be limited to 20. (Reference citation of a website is not acceptable unless a site is the sole source of the information or has official academic credentials. Examples of acceptable sites are official government web pages such as that of the National Institutes of Health.)
• The Pharos Editorial Board suggests that authors review George Orwell’s “6 Rules for Writing”.
• Essays that are not selected as award recipients may be submitted to other contests/publications after the winners are announced.
• Essays not meeting all requirements will not be considered.

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Arthur S. Bensell Memorial Scholarship

Arthur S. Bensell was an educator, civic leader, Tribal Council member and Tribal Chairman. He spent many years in service to his community and Tribe as Mayor of the City of Siletz and tribal leader.

Art attended Ohio State University and graduated from Heidelberg College in 1934. During his career with the Bureau of Indian Affairs, he served as a teacher, principal and reservation principal in Minnesota, Alaska and North Dakota. Upon returning to Siletz, Art became involved in tribal business affairs and served many years on the Tribe’s Education Committee and always strived for better educational opportunities for Tribal members.

A memorial scholarship fund was established through the Confederated Tribes of Siletz Indians to honor and award Tribal members in education. The $1000 scholarship is administered by the Tribal Education Committee and strengthened by various fund raising activities throughout the year.

Self-Defense Grants for MMIR Day

Facilitators, educators, organizers — May 5th is the Day of Awareness for Missing & Murdered Indigenous Women, Girls and Relatives. In honor of that day, we are offering mini grants to host a self-defense workshop for Indigenous girls and gender-expansive youth.

Why self-defense?

• Native women are murdered at 10x the national rate
• 84% experience violence in their lifetime
• Over 5,700 Native girls go missing each year

We also name the invisible crisis:

• Indigenous people from Mexico & Central America (Maya, Nahua, Zapotec, Mixtec, Lenca, and others) living in the U.S. face detention, deportation, and disappearances that are rarely counted in MMIR data.
• When a Tzotzil 18 year old like Royer Perez Jimenez dies in ICE custody, the silence is deafening.

Self-defense must include all Indigenous relatives.

XCNC has:

• $500 mini grants for stipends, space, supplies, and translation.

What we ask:

• Plan a workshop between May 5–31, 2026, rooted in community care.

The Brice and Teresa Moczygemba Engineering Scholarship Fund, established by the San Antonio Area Foundation, supports students pursuing a Bachelor's degree in Civil Engineering from accredited programs in the U.S. Eligible applicants include current high school seniors and college students residing in Bexar, Karnes, or Wilson counties, with a minimum GPA of 3.6. This renewable scholarship covers tuition, fees, books, and educational expenses, reinforcing the Foundation's commitment to enhancing community well-being.

The Creation & Development Fund, administered by the National Performance Network, supports the creation and mobility of artistic works that promote racial and cultural justice. It fosters collaboration between artists and communities through financial support, enabling artists to develop meaningful relationships and present their work. The fund emphasizes equity, access, and the importance of public engagement, ensuring that diverse voices are represented while addressing systemic injustices in the arts.

The ACS-Hach High School Chemistry Classroom Grant aims to enhance chemistry education by providing funding for innovative teaching ideas. Since its inception in 2008, over 700 teachers have benefited from grants of up to $1,800. Eligible applicants are U.S. high school chemistry educators, and the funding can be used for laboratory supplies, instructional materials, professional development, and student-led field studies, fostering a deeper understanding of chemistry.

The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.

The Civic Experiment Grant by the Trust for Civic Life supports innovative, community-driven projects aimed at enhancing civic engagement. It focuses on rural areas, empowering local leaders to tackle challenges collaboratively. Grants up to $25,000 are available for organizations that are non-partisan and primarily serve rural communities, emphasizing inclusivity and sustainable impact. The next nomination period begins in early 2026, following a closed cycle for 2025. This initiative fosters long-term civic infrastructure and community resilience.

Dr. Jill Biden Scholarship - Biden Breast Health Initiative

Essay:

• Why have you chosen a career in health care or education, and why do you feel it is important to encourage others to adopt a healthy lifestyle?

Awards:

• One time award of $2,500; one award per county. 

The Ray Y Gildea Jr Award, provided by the Royal Geographical Society, offers grants of up to £1,000 to support innovative teaching methods in higher and secondary education. This endowed award aims to enhance geography education by funding projects that develop, research, or pilot new approaches, ultimately benefiting students directly. Eligible applicants must be actively teaching in the higher education or secondary school sectors in the UK or USA.

The Greenwall Foundation invites nominations for the 2025 Bernard Lo, MD Award in Bioethics, a prestigious $25,000 prize recognizing outstanding contributions to bioethics. This award highlights exceptional mentorship in bioethics, celebrating individuals who support rising professionals across diverse sectors, including academia, government, and public health. Nominations can be made by mentees and colleagues, fostering an inclusive recognition of mentorship excellence. Renominations are encouraged, but self-nominations are not allowed.

The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.

The Paul Purcell "Kids Win!" Annual Baird Education Grant honors the legacy of former Baird CEO Paul E. Purcell, who dedicated his life to educational causes. Established in 2020, this grant supports 501(c)(3) organizations that ensure all children, regardless of circumstances, have access to quality education. Funded by Baird and its associates, it prioritizes programs serving diverse and underserved populations, embodying Purcell's belief that every child deserves the opportunity to succeed.

The Greenwall Foundation invites proposals for its Bridging Bioethics Research & Policymaking Grants, aimed at integrating bioethics into policy without funding academic research. This initiative addresses ethical dilemmas arising from healthcare advancements, encouraging innovative project ideas at all governmental levels. Grants up to $50,000 will prioritize projects with smaller budgets and shorter timelines. Collaborations with diverse expertise beyond academia, including policymakers, are encouraged to effectively bridge research and policy.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.

The Institute of Education Sciences (IES) offers research training programs aimed at advancing education research through two key initiatives: the Early Career Development and Mentoring Program and the Methods Training Program. These programs support emerging researchers in developing their skills and enhancing their research capabilities to address vital education issues. The funding is designed for early career investigators and current education researchers, fostering rigorous and relevant research that informs education policy and practice.

About Borealis Philanthropy

Borealis Philanthropy is a philanthropic social justice intermediary that works to resource grassroots leaders and social justice movements for transformative change. We help funders expand their reach and strengthen their impact through donor collaboratives that support a variety of issues, communities, and movements. Borealis is home to nine donor collaboratives, including the Disability Inclusion Fund and Disability x Tech.

DIF x Tech Fund

For the Disability Inclusion Fund at Borealis, part of our efforts for disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. The DIF x Tech initiative, supported by the Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest, invites proposals that are working to bring about transformational change at the intersections of disability, justice, and technology

About the Disability Inclusion Fund and DIF x Tech

The Disability Inclusion Fund (DIF) supports U.S.-based groups run by and for people with disabilities to lead transformational change. The Fund is supported by donors including the Presidents’ Council on Disability Inclusion in Philanthropy, which is comprised of foundation presidents who are committed to disability inclusion as part of improving diversity, equity, and inclusion within philanthropy.

Part of the efforts of disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. This newly launched initiative is housed at the Disability Inclusion Fund (DIF) and supported by Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest. 

DIF x Tech Fund Values

All Disability x Tech award decisions will align with the DIF guiding values. The DIF guiding values are:

• Participation: Movement funding accountable to the disability rights movement. Those impacted by injustice/exclusion should be involved in strategies to advance justice/inclusion.
• Intersectionality: Acknowledging that disabled people have multiple and intersecting social and political identities that can influence their ability to have access and inclusion including race, gender identity, class, sexual orientation.
• Radical inclusion: Deeply committed to removing barriers and ensuring access so that those most affected by intersecting identities can participate, valuing lived experience.
• Leadership of those most impacted by ableism: Emphasis is given to organizations led by people subject to systemic bias and impacted by underrepresentation, particularly disabled people of color, queer, gender nonconforming and women with disabilities.
• Cross-movement solidarity: Intentional focus on collaboration and bridge- building amongst disability justice activists and across movements.
• Sustainability: Resources and tools that support the growth of grassroots disabled-led organizations, and expand operational capacities for ongoing movement building. 

What we fund

We invite proposals that are at the nexus of technology, disability rights and justice. This opportunity may be a good fit for your organization, if you are doing work in any of these areas below:

• Disabled people sharing technical skills and knowledge with others in the community.
• Disabled people leading policy, rights, and disability justice activism work related to tech. 
• Disabled people participate in all stages of the design and development of new tech that will enrich lives of people with disabilities.
• Enabling collective and equitable access to digital infrastructure. 
• Expanding the participation, leadership, and thought partnership of overlooked and under-resourced people with disabilities in all areas of the technology sector.
• Partnerships between disability-focused engineering design labs and maker spaces within schools, centers for independent living, or local nonprofit organizations.
• Permissible Policy Work:
  • We may support nonpartisan policy education and advocacy related to disability and technology. Any lobbying must remain within applicable 501(c)(3) limits and Borealis grant restrictions.

The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.

Steven Thayer Hopi Scholarship

This scholarship was established by the family of Steven Thayer to provide scholarship funding for young Hopi artists to develop their talents and artistic skill.