Best Small Grants for Nonprofits in Massachusetts

The DOE Computational Science Graduate Fellowship (CSGF) supports U.S. citizens and permanent residents pursuing Ph.D. degrees in computational sciences. Established in 1991, it provides a $45,000 annual stipend, full tuition, and a $1,000 professional development allowance over a maximum of four years. The program encourages interdisciplinary research, offering fellows practical experience in DOE laboratories, enhancing their careers in high-performance computing and scientific research across various fields.

The See, Test & Treat Grant offers vital funding for cancer screening and health education programs targeting medically underserved communities. This pathologist-led initiative aims to reduce healthcare barriers, empower preventive care, and connect patients with local resources. Eligible organizations can apply for up to $50,000 over three years, fostering sustainable health improvements. The program emphasizes same-day results for screenings and culturally appropriate education, ensuring equitable access to essential healthcare services.

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

Samardzija-Gutesha Family Fund

The Field of Interest Fund reflects the Samardzija-Gutesha family’s values and commitment to giving back. It supports education and hands-on learning in farming, soil health, and water conservation, with a focus on FFA members and associate-level college students.

Scholarships benefit graduating seniors and second-year post-high school students who are originally from DeKalb County high schools with FFA programs.

The Samardzija-Gutesha Family Fund provides scholarships for post-high school students pursuing education in agriculture or conservation, as well as paid internships with local farmers, and conservation professionals. It also supports educational seminars on topics such as sustainable farming and agricultural business, and provides grants to local organizations that align with the donor’s values.

In its first year, the Fund awarded $65,000 in scholarships to eight graduating seniors from DeKalb, Genoa-Kingston, Indian Creek, Somonauk, and Sycamore high schools (pictured above). Each student attending a two-year college received a $5,000 scholarship, while students planning to attend a four-year university received $10,000.

The Building Hope: Future Forward Schools Prize & Fellowship Program aims to enhance career exploration for middle and high school students. This initiative, launched by Building Hope in partnership with American Student Assistance, recognizes schools that excel in career-connected learning. Awardees receive funding, mentorship, and resources to empower students from diverse backgrounds, ensuring they develop essential skills for future success. With $50,000 available for five schools, this program fosters innovation and prepares students for a changing economy.

The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.

The Walking Classroom Grant Program, offered by the Alliance for a Healthier Generation, enables classroom teachers in public schools to receive donated materials for their students. This innovative program promotes physical activity while maintaining instructional time through engaging podcasts. Ideal for grades 3-8, it enhances cognitive function and retention. Schools with the greatest need, both socioeconomically and academically, are prioritized, ensuring that all students can benefit from this unique educational approach.

The Furer-Barag-Wolf Post 126 Jewish War Veterans Scholarship Award supports children or grandchildren of JWV Post 126 members, providing merit-based assistance for college or vocational education. Eligible applicants must reside in specific counties in New Jersey or be related to a JWV member. The scholarship covers tuition, books, and living expenses and is open for reapplication annually. This initiative by the Jewish Community Foundation fosters educational opportunities for deserving students.

The U.S. Department of Health & Human Services, through the NIH, invites applications for the U01 grant aimed at advancing gene-based therapies for ultra-rare neurological and neuromuscular disorders. This initiative focuses on IND-enabling studies and supports the development of innovative therapeutics with proven biological rationale. Applications must include robust data and compelling justification for the proposed clinical candidates, targeting a specific patient population to facilitate IND filing and subsequent clinical trials.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS)

Help with healthcare costs for Multiple sclerosis (MS)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

The Southern NM Down Syndrome Families Scholarship Fund Endowment aims to provide financial support for individuals with Down syndrome pursuing post-secondary education or life skills training at accredited institutions. Managed by the Community Foundation of Southern New Mexico, this scholarship embodies the mission of improving quality of life and fostering educational opportunities for diverse communities. It encourages applicants from various backgrounds, including those with disabilities, to achieve their academic and personal goals.

The Carl Alwin Schenck Award, presented by the Society of American Foresters, honors exemplary contributions in forestry education. This prestigious award recognizes individuals with at least ten years of professional experience who demonstrate outstanding teaching abilities and commitment to forestry. Awardees receive a $500 honorarium, complimentary registration for the SAF national convention, and up to $500 for travel expenses. This award underlines the importance of effective education in advancing sustainable forestry practices.

The Agriculture and Food Research Initiative (AFRI) focuses on enhancing education and workforce development in food and agricultural sciences. It invites applications for various grants aimed at professional development, non-formal education for youth, community college training, and fellowships for both predoctoral and postdoctoral candidates. The program, managed by the USDA's National Institute of Food and Agriculture, emphasizes the cultivation of skills necessary for the future workforce in agriculture, with multiple deadlines for submissions.

The Community Experts Fund Grant, provided by the Peter & Elizabeth C. Tower Foundation, aims to improve the lives of young people facing mental health and developmental challenges in targeted counties. With $350,000 available in 2025, the fund emphasizes mentoring initiatives that empower youth-driven goals. By strengthening existing programs, it seeks to build capacity and support young individuals through quality one-on-one mentoring, distinct from traditional case management, addressing the pressing needs of this vulnerable population.

The Indigenous Scholarships: Arts Fund facilitates artistic development for Aboriginal Australian, Torres Strait Islander, Native American, Alaskan Native, and Native Hawaiian artists. Offering up to $5,000, it supports projects in each other's countries, with applications due in March and September. Since 2002, over $1 million has been awarded to more than 500 artists, fostering cultural exchange and growth in the arts between Australia and the USA.

The Ag Health and Safety Grants, awarded by CHS and the CHS Foundation, aim to enhance agricultural safety and foster community well-being. These grants focus on educating youth and farmers about agricultural hazards, providing training for rural professionals, and developing essential safety guidelines. With a commitment to improving safety standards, the program has benefitted over 32,000 youth and supported more than 450 communities through safety initiatives and equipment, ensuring a safer future for all involved in agriculture.

The Saab Family Foundation Grant offers support to tax-exempt organizations in Rockingham and Hillsborough Counties in NH, as well as Essex and Middlesex Counties in MA. Established in 2010, the foundation focuses on enhancing the lives of individuals in need, particularly in education, youth services, elderly care, and housing assistance. Grants are aimed at public charities that foster social responsibility and contribute to positive community outcomes.

The HEAL Initiative's Career Development Awards aim to empower early career researchers and clinicians in implementation science. By providing training and funding, this initiative seeks to address substance use prevention and treatment through research projects that align with the HHS Overdose Prevention Strategy. Focused on vital areas such as opioid prescribing, OUD treatment, and recovery support, the program aspires to cultivate a new generation of experts who will significantly impact addiction clinical practices and mentorship.

About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.

We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:

• Proof of college enrollment or acceptance
• Pursuing a degree with the goal of working with individuals and/or families impacted by addiction
• Completed application form
• An original 500 to 1000 word essay on how you are planning to use your degree to help individuals and families struggling with addiction, and why helping those affected by substance use disorder is important to you

The Utility Arborist Research Fund Grant Program, managed by the TREE Fund and UAA, offers $50,000 in funding for 2024 to support vital research in utility tree care. The program prioritizes proposals focusing on employee safety, service reliability, and regulatory compliance. Grants range from $10,000 to $50,000, with the aim of addressing pressing issues in vegetation management. Applications are welcomed from those aligned with these priorities, promoting safety and efficiency in the utility industry.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Eosinophilic esophagitis

Help with healthcare costs for eosinophilic esophagitis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Eosinophilic Esophagitis (EoE) is a disorder of the esophagus and is increasingly recognized as a major cause of swallowing difficulties in children and adults. It is a chronic disease of the immune system and can be triggered by a food allergy, acid reflux, or an airborne allergy. An allergic trigger causes the immune system to overact which causes many white blood cells, or eosinophils, to collect in the esophagus. This causes the esophagus to become inflamed and not contract properly. The esophagus can also narrow and develop rings or abscesses. This condition can become worse over time.

The BIE Professional Development Funding for STEM Educators and Students, offered by the Native Forward Scholars Fund, supports training opportunities in science, technology, engineering, and mathematics (STEM) for TCU faculty, staff, and students. This funding assists with costs related to professional development including continuing education, conferences, and certifications. Eligible applicants include educators at BIE-funded or controlled schools, as well as those at institutions with significant Native American populations, fostering increased representation and support for Native scholars.

The Presbyterian Church (U.S.A.) offers financial support through undergraduate scholarships for up to 100 eligible college students each year. Applicants must be members of PC(USA) pursuing their first associates or bachelor's degree at an accredited institution in the U.S. during the 2025-2026 academic year. This initiative aims to assist students in overcoming financial barriers to education while fostering a commitment to service within their communities.

The Community Charter Network Scholarship, provided by the Central Indiana Community Foundation, assists students from Fall Creek Academy or University Heights Preparatory Academy in covering post-secondary educational expenses. This scholarship aims to support those who demonstrate financial need and excel academically. Eligible applicants include former students of these institutions or residents within the IPS district. Awards vary based on available funds and may cover tuition, fees, and other educational costs.

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Brian Edkins Memorial Scholarship

Graduating senior from Cape Fear High School; South View High School (Cumberland County) or Scotland High School (Scotland County, NC).

The SAF National Awards Program recognizes exceptional student leaders in forestry. The Student Leadership Award honors an SAF student member demonstrating leadership skills at various levels. Recipients receive a $200 honorarium, complimentary convention registration, and up to $500 for travel expenses. Additionally, the recipient's faculty advisor and SAF Student Chapter benefit from $150 each. This award aims to encourage student engagement and excellence in sustainable forestry and resource management.