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Best Unrestricted Grants for Nonprofits in Michigan

Find the perfect Unrestricted grants for nonprofits in Michigan on Instrumentl. 10,000+ Unrestricted grants for nonprofits in Michigan in the United States.

10,000+

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$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,957 Results based on applied filters

Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant

National Scleroderma Foundation
Private
United States
US $200,000
The Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant, provided by the National Scleroderma Foundation, aims to support research in scleroderma-related lung disease. With a funding amount of $200,000, the grant encourages established investigators to explore innovative solutions and enhance understanding of this condition, ultimately working towards improving the quality of life for affected individuals and advancing medical knowledge in the field.
Rare Diseases Immune System Diseases Interstitial Lung Disease

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

RRCU Gives Foundation Grant

RRCU Gives Foundation
Association/Society
United States
Unspecified amount

RRCU Gives Foundation Grant

Mission Statement:

RRCU Gives strengthens our region by providing meaningful financial support to nonprofits addressing hunger, housing, and financial education. Through our annual grant awards and major funding initiatives, we help local organizations grow, thrive, and create lasting change.

 We award grants annually, with applications in June and awards in August.

Focus Areas

  • Hunger
  • Housing
  • Financial Education
Food Access & Hunger Financial Literacy Equitable & Affordable Housing

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

Single Ventricle Research Fund (SVRF) - Independent Investigator Track

Additional Ventures Foundation
Private
Countries
Up to US $600,000
The Single Ventricle Research Fund (SVRF) offers annual grants aimed at enhancing research and care for individuals with single ventricle heart defects. With awards of up to $600,000, the SVRF encourages innovative projects that align with the Additional Ventures Research Roadmap. This initiative not only supports novel treatments but also fosters collaboration across disciplines to address critical challenges in single ventricle heart disease management.
Cardiovascular Diseases & Systems Heart Disease Preventative Healthcare

Scaling Pathways to Homeownership

Capital One Foundation
Corporate
American Samoa, Guam +4 more
US $200,000
  • Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
  • Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
  • Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
  • Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.
Homeownership Equitable & Affordable Housing

Muskegon County Housing Initiative: Strategic Leadership Grants

Community Foundation for Muskegon County
Private
Muskegon County, Michigan
US $20,000 - US $50,000

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Grant Opportunities

At the Community Foundation for Muskegon County, we support programs that drive lasting change. Through grants, we partner with local organizations to meet the diverse needs of our community and fulfill our donors’ goals to improve life in Muskegon County, both now and in the future.

Muskegon County Housing Initiative

Strategic Leadership Grants: A Call for Housing Proposals

The Community Foundation’s vision to build a vibrant community with great opportunities for all serves as the basis for our values: hope and opportunity, particularly for youth; collaborative community goals and decision-making; and an inclusive community.

In the fall of 2023, the Community Foundation, collaborating with local municipalities and economic development agencies, commissioned a study on Muskegon County’s current needs and opportunities. The study revealed that Muskegon County needs 9,000 housing and rental units across the housing continuum over the next five years to meet demand and stabilize the local housing market. You can read the full results of the study HERE.

To help increase the availability, accessibility, and affordability of housing, the Community Foundation has committed at least $1M in grants and up to $5M in loans to support local housing efforts.

Housing Grants

Nonprofit organizations, including schools, governmental units, and faith-based organizations, must initiate grant requests. Strategies may include for-profit partners and collaborators.

Priority for grants will be given to suggested projects such as:

  • First-time homeowners’ assistance, including home-ownership education
  • Developer incentives with a focus on workforce housing (180% AMI)
  • Explore options to preserve affordability, such as the creation of a Land Trust
  • Work with current landlords to facilitate a transition to homeownership for tenants in good standing
  • Work with municipalities to incentivize implementation of zoning best practices and tools to incentivize development
  • Invest in supporting seniors in a transition to their next phase of housing 

In addition, the Community Foundation is working collaboratively with leadership from the City of Muskegon Heights as a geographic focus area for investment in publicly owned lands. Grants and loans will be made to projects that meet at least one of the following:

  • Purchase and remediate public land and/or blighted properties to prep for development
  • Create development packages around publicly owned land in Muskegon Heights to incentivize development
  • Support home improvements for neighboring properties
  • Support for community listening sessions to create a shared vision around public land development for housing

At least $1,000,000 will be granted over the next few years. We envision that multiple grants will be supported in the $20,000-$50,000 range. Multiyear requests, with phased-out funding over three years, will be considered.

Homeownership Equitable & Affordable Housing

Comprehensive Suicide Prevention Program for States (363329)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $650,000 - US $1,200,000
The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.
Suicide Prevention

Trail Accelerator Grants- Spring Cycle Planning and Design

International Mountain Bicycling Association
Private
United States
US $10,000 - US $30,000
The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.
Trail Creation & Maintenance Biking Pedestrian & Bike-Friendly Infrastructure

Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) (348960)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.
HIV / AIDS

Accelerating Research and Development of Next Generation Malaria Vaccines Against Malaria – A Model for Mosquito-Borne Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.
Malaria Tropical Diseases

HIV/AIDS Clinical Trials Network Leadership and Operations Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is calling for applications for four Leadership and Operations Centers (LOCs) as part of its HIV/AIDS Clinical Trials Network initiative. These LOCs will guide research on HIV therapeutics, prevention, and treatment strategies across diverse populations. The initiative aims to enhance evidence-based practices and improve health outcomes for individuals affected by HIV, ultimately contributing to the goal of ending the HIV epidemic.
HIV / AIDS

Grief Reach: Changemaker Supported Community Expansion Cycle - up to $110,000

National Alliance for Children's Grief (NACG)
Private
United States
Up to US $110,000
The Grief Reach: Changemaker Supported Community Expansion Cycle offers up to $110,000 to enhance community programs for grieving children. Organizations are encouraged to innovate and expand their services to better meet community needs. The initiative, in partnership with the Judi’s House/JAG Institute, emphasizes training and resources for effective program evaluation over a three-year period, culminating in impactful community expansion projects.
Children’s Mental Health Mental Health & Psychiatric Diseases Family Services +1 more

HIV/AIDS Clinical Trials Network Laboratory Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for up to four Clinical Trials Network Laboratory Centers (LCs). These LCs will support HIV prevention and treatment strategies by providing necessary laboratory infrastructure and technologies for clinical trials. They will ensure rigorous laboratory testing and oversight, enhance sample integrity, and utilize advanced data management systems to meet evolving demands in HIV research and testing.
HIV / AIDS

Wild Animal Initiative: Seed Grants

Wild Animal Initiative
Private
Afghanistan, Albania +189 more
Up to US $30,000
The Wild Animal Initiative offers Seed Grants to support innovative projects in wild animal welfare research. These grants aim to facilitate early-career researchers and established scientists in testing new techniques and approaches that incorporate welfare assessments into ecological studies. The program emphasizes cost-effective solutions, focusing on improving the welfare of wild animals. Successful proposals will explore diverse themes such as wild fish welfare and near-term welfare interventions to address urgent animal welfare challenges.
Wildlife Health Ichthyology (Fish)

HIV/AIDS Clinical Trials Network Clinical Trials Units

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for Clinical Trials Units (CTUs) as part of its effort to combat HIV/AIDS. This initiative aims to support innovative clinical trials and implementation research to improve prevention and treatment strategies. With a focus on both domestic and international research sites, CTUs will play a crucial role in addressing the HIV epidemic and enhancing participant recruitment and retention. This funding opportunity is authorized under the Public Health Service Act.
HIV / AIDS

Jack Kent Cooke Foundation: Young Scholars Program

Jack Kent Cooke Foundation
Private
United States
Unspecified amount

Jack Kent Cooke Foundation

The Jack Kent Cooke Foundation is dedicated to advancing the education of exceptionally promising students who have financial need. Since 2000, the Foundation has awarded $304 million in scholarships to more than 3,400 students from 8th grade through graduate school, along with comprehensive academic advising, career pathway counseling and other support services. The Foundation has also provided $136 million in grants to organizations that serve such students.

The Jack Kent Cooke Foundation’s scholarship programs are designed to encourage and support outstanding students who work hard and have financial need. Our scholarships provide financial assistance and academic support to high school, undergraduate, and graduate students. In addition to the monetary award, students join a thriving network of more than 3,400 Cooke Scholars.

Young Scholars Program

The Cooke Young Scholars Program is a selective five-year, pre-college scholarship for exceptionally promising 7th grade students with financial need. It provides comprehensive academic and college advising, as well as financial support for school, Cooke-sponsored summer programs, internships, and other learning enrichment opportunities.

Program Experience

Educational Advisers support Young Scholars to maximize high school experiences and to go on to thrive at the nation’s top-performing colleges. Our programming and support may include:

  • Identifying an appropriately rigorous high school.
  • Engaging in four-year planning and goal-setting.
  • Funding for academic and extracurricular opportunities, such as music and art lessons, supplemental academic classes and technology.
  • Annual summer programs, including two required Young Scholar programs.
  • Year-round Young Scholars community programming.
  • Networking opportunities with a high-achieving peer community.

Academic Success & Enrichment After School / Summer Educational Programs Career / College Preparation +2 more

Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $212,004 - US $2,725,311
This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.
HIV / AIDS

Geoff Richter Performing Arts Award

Foundation For Jewish Philanthropies
Private
United States
US $2,000

Our Mission

Empower donors to fulfill their passions and dreams by establishing charitable vehicles designed to create a positive and enduring impact on Jewish Buffalo, Western New York and the World.

Geoff Richter Performing Arts Award

The Geoff Richter Performing Arts Award Committee announces the availability of an Award up to $2,000! The GRPAA was founded in memory of Geoff Richter, Western New York Musician and Educator of the Arts.

About Geoff Richter

A native of Eden, New York, Geoff received his Bachelor of Music degree with a Performer’s Certificate in trumpet and a Master’s with a Performers Fellowship, from the Eastman School of Music.

Geoff played trumpet professionally with the Rochester, San Antonio, and Buffalo Philharmonic Orchestras and Niagara Falls, Binghamton, Chautauqua, Orchard Park, Clarence, Cheektowaga, and Amherst Symphony Orchestras. He co-founded the Buffalo Brass Quintet, the Buffalo Niagara Concert Band, and The Frankfurters, an internationally known Bavarian show band. He also acted as the summer/pops conductor of the Erie County Wind Ensemble and the Amherst Symphony Orchestra.

After retiring from a long career at Williamsville North High School, Geoff started working part time as director of the orchestra for musicals at St. Joseph Collegiate Institute. He also worked with the Mount Saint Mary Academy band and recruited and directed the orchestra for the annual school musical.

Performing Arts Education - Higher Education Music +2 more

Carl Hill Memorial Scholarship

Delaware Community Foundation
Private
United States
US $500

Carl Hill Memorial Scholarship

Awards:

  • One time award of $500.
Education - Higher Education Financial Literacy Business Education +1 more

TERF Research Grants

Thoroughbred Education and Research Foundation
Association/Society
United States
Unspecified amount
The Thoroughbred Education and Research Foundation (TERF) offers grants to support thoroughbred health, welfare, and education. Focused on enhancing equine research and safety in racing, TERF prioritizes funding for scholarships, educational programs, and veterinary medicine. Eligible applicants must be recognized 501(c)(3) organizations, with a commitment to transparency in reporting. This initiative aims to significantly impact the thoroughbred industry by fostering improved care and understanding of these horses, contributing to their overall welfare.
Mammalogy

Fruit of the Vine Scholarship

Napa Valley Community Foundation
Private
United States
US $2,000 - US $4,000

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Fruit of the Vine Scholarship

The Fruit of the Vine Scholarship Fund benefits graduating Napa County high school seniors and Napa Valley College transfer students who will find the cost of higher education a financial hardship. Consideration is given to applicants who are the first in their family to attend college or are employed (or have a parent or guardian who is employed) in the Napa County wine or grape industry. Recipients of the scholarship will receive funding for up to four years of undergraduate study.

Education - Higher Education Viticulture Academic Scholarship Programs +1 more

TERF Education Grants

Thoroughbred Education and Research Foundation
Association/Society
United States
Unspecified amount
The Thoroughbred Education and Research Foundation (TERF) offers grants to support education and research related to Thoroughbred horses. The foundation prioritizes funding for scholarships, educational programs, and equine research aimed at promoting thoroughbred health and welfare. Eligible applicants include qualified 501(c)(3) organizations, while those previously funded must submit reports before applying again. Notably, TERF does not provide funds for facilities caring for unwanted horses or cover overhead costs for grants.
Mammalogy

Presenter Consortium for Jazz Grant

Chamber Music America
Private
United States
Up to US $15,000
The Presenter Consortium for Jazz Grant, offered by Chamber Music America, supports U.S.-based presenters collaborating to engage professional jazz ensembles. This grant provides up to $39,000 for expenses like ensemble fees, concert production, and marketing. Each consortium can include up to three presenters and aims to enhance the jazz experience through live performances and streamed concerts. Eligible projects must involve CMA’s New Jazz Works grantees, fostering creativity and community engagement in jazz.
Chamber Music

Enhancing Pastoral and Social Ministry Grants

Catholic Extension
Association/Society
Acadia Parish, Louisiana, Accomack County, Virginia +994 more
Unspecified amount
Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.
Catholicism Family Services Homelessness Services +3 more

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) (357231)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,500,000
The NHLBI SBIR Phase IIB Small Market Awards aim to accelerate the commercialization of innovative technologies targeting heart, lung, blood, and sleep disorders. This funding opportunity addresses the significant gap between SBIR Phase II awards and regulatory approval. Small businesses focusing on rare diseases or young pediatric populations are encouraged to apply, fostering partnerships with investors and advocacy groups to advance projects toward commercialization and regulatory clearance.
Medical Technology, Devices, and Equipment Cardiovascular Diseases & Systems Hematological Systems +2 more

Bob Skiera Memorial Fund Building Bridges Initiative and John P. White Grant Program

Tree Fund
Association/Society
United States
US $5,000 - US $30,000
The Bob Skiera Memorial Fund Building Bridges Initiative Grant Program supports urban forestry research and collaboration. With a maximum award of $30,000, it aims to enhance communication between arborists, urban foresters, and various professionals. The program welcomes proposals that explore the benefits of urban forests, policy implementation, and ecosystem services. This initiative honors Bob Skiera's legacy, fostering trust and cooperation within the urban planning community for sustainable urban forestry practices.
Forestry

Unrestricted Grants for Nonprofits in Michigan Highlights

Looking for unrestricted grants for nonprofits in Michigan?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in Michigan recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in Michigan

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Unrestricted grants for nonprofits in Michigan grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Unrestricted grants for nonprofits in Michigan over $25K in average grant size

43 Unrestricted grants for nonprofits in Michigan over $50K in average grant size

34 Unrestricted grants for nonprofits in Michigan supporting general operating expenses

100+ Unrestricted grants for nonprofits in Michigan supporting programs / projects

600+ Grants on Instrumentl focused on Poverty Alleviation & Services

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in Michigan?

Most grants are due in the second quarter.

Q1
26.9%
Q2
27.2%
Q3
23.8%
Q4
22.0%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in Michigan?

Grants are most commonly $25,000.

$500 $500 Min.
$25,000 $25 K Median
$514,253 $514.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Michigan?

Grants are most commonly $89,949.

$89,949

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in Michigan year over year?

In 2024, funders in Michigan awarded a total of 65,465 grants.

2022 59,390

2023 60,659

2024 65,465

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in Michigan given out in Michigan, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in Michigan changing over time?

Funding has increased by 4.77%.

2022 $5,494,510,387

2023 $5,608,918,451
2.08%

2024 $5,876,731,534
4.77%

Michigan Counties That Receive the Most Funding

How does grant funding vary by county?

Wayne County, Kent County, and Oakland County receive the most funding.

County Total Grant Funding in 2024
Wayne County $1,257,959,859
Kent County $782,573,802
Oakland County $610,681,665
Washtenaw County $550,205,535
Calhoun County $444,453,435