Best Grants for 501(c)(3) in Minnesota

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

The National Cancer Institute (NCI) plans to issue a Notice of Funding Opportunity (NOFO) for the Paul Calabresi Career Development Award in Clinical Oncology (K12). This program aims to enhance training for clinician-scientists in cancer research, fostering their career development and collaboration with basic research scientists. It mandates diverse oncology specialties in faculty, individualized career development plans, and mentorship, supporting Scholars for up to three years to promote their research initiatives in clinical trials.

The Spight Family Foundation Grants aim to enhance the well-being of families and support environmental initiatives that benefit future generations. They welcome charitable organizations that align with their mission, regardless of location, with a primary focus on Northern California. By funding various projects, the foundation seeks to foster community health and sustainability, making a lasting impact on both local and global scales.

The Historical Transportation Marker Program provides grants to commemorate significant transportation methods used before 1945, such as canals, bridges, railroads, and aircraft. Eligible applicants include 501(c)(3) organizations and government entities in the U.S. Grants aim to recognize historical facts with clear inscriptions, supported by documentation, while ensuring markers are publicly accessible near existing sites. This initiative highlights the evolution of transportation and its impact on community development.

The Katie Cannon Scholarship honors Rev. Dr. Katie Geneva Cannon, a pioneering figure in the Presbyterian Church (U.S.A.). This scholarship aims to empower Presbyterian women of color, clergywomen, and college women by providing financial assistance for leadership development events and educational opportunities. It promotes spiritual growth and mission involvement within the church, ensuring that women are equipped for greater service and leadership roles. This fund is part of the Women's Ministry Fund at the Presbyterian Mission Agency.

The Paul Calabresi Career Development Award for Clinical Oncology aims to enhance the training of clinician-scientists in clinical and translational cancer research. This funding opportunity encourages the career growth of researchers but does not permit Scholars to lead independent clinical trials. Instead, it allows participation in clinical trials under the mentorship of an experienced researcher, fostering a collaborative approach to cancer research.

The Partnership Agreement Grants for FY 2027, offered by the National Endowment for the Arts (NEA), support state and regional arts agencies in enhancing community arts accessibility. These grants leverage federal funding to attract significantly more state contributions, fostering a robust federal-state partnership. Each state arts agency develops a tailored arts plan, ensuring that local priorities and goals are effectively addressed. This collaborative approach amplifies the impact of federal arts funding across the nation.

About RWJF

At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.

Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.

Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system. 

The Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership (ESSSP) aims to enhance NOAA's mission through collaborative research and activities. It focuses on understanding changes in Earth's systems and their impacts on ecosystems and communities. Eligible applicants include academic institutions offering doctoral degrees in NOAA-related sciences. The total funding available is approximately $10 million, supporting initiatives that encompass research, data evaluations, and stakeholder engagement.

The Douglas Dockery Thomas Fellowship in Garden History and Design, established by the Garden Club of America, supports graduate students in studying and researching garden history and design. This annual fellowship promotes the GCA’s commitment to gardening education and conservation. Research topics may include innovative garden restoration techniques and the impact of community gardens. The fellowship aims to nurture talent and address the growing importance of gardens in our environment.

The Alex Stern Family Foundation Grant provides funding to nonprofits in the Fargo-Moorhead area, focusing on arts, education, social welfare, youth recreation, civic projects, and health issues. Established by Alex Stern, a notable community figure, the foundation aims to support initiatives that enhance the local quality of life. Organizations seeking assistance should confirm their eligibility with the Program Manager before applying, ensuring alignment with the foundation's mission.

The NeuroNEXT Small Business Innovation program invites small businesses to apply for exploratory clinical trials involving investigational agents, including drugs, biologics, and devices. These trials aim to gather critical data to support the design of future clinical studies, particularly focusing on diseases aligned with the NINDS strategic plan. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.

The Donaghue Foundation's Greater Value Portfolio Grant Program aims to enhance healthcare value by funding innovative research projects for two years, with awards up to $400,000. It encourages proposals that address issues such as high costs, disparities, and inefficiencies in care. Eligible applicants include Ph.D. researchers at nonprofit institutions partnered with healthcare organizations. The program seeks actionable solutions to improve patient care and reduce the burden of low-value healthcare on communities.

The Health Workforce Research Center (HWRC) aims to enhance understanding of health workforce needs across various levels of governance. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative supports vital research that informs decision-makers, ensuring effective resource allocation and workforce planning to meet healthcare demands.

About Knight Foundation

John S. and James L. Knight believed that a well-informed community could best “determine its own true interests” and was essential to a well-functioning, thriving democracy. They pursued those beliefs, building and leading one of the largest and most successful newspaper companies in American history.

For 75 years, Knight Foundation has supported the people, ideas and insights that lead to thriving communities. The foundation invests in local journalism, arts and culture and community development in the 26 cities and towns where the Knight brothers once published newspapers.

Since our founding in 1950, we have been committed to the communities we serve and to providing those communities with the tools they need for residents to thrive.

Knight Cities Challenge

Knight Foundation is currently accepting applications for the Knight Cities Challenge, a $5 million open call inviting individuals and organizations across its 26 communities to submit new, creative ideas for projects that can spark change and leave a lasting local impact.

Building on a long history of open challenges across programs, Knight democratizes access to grantmaking to unlock the best and brightest ideas. This spring, KCC returns to invest in its first cohort of community-centered solutions to local challenges and help promising ideas take root and grow.

Project ideas must focus on at least one of Knight’s investment areas: strengthening local news and information, creating pathways for economic opportunity or cultivating connection through arts, culture and the places that bring people together.

You may submit one idea, either as an individual or on behalf of your organization. While you are limited to one application as the lead applicant, you may collaborate on other projects submitted by different partners. Each individual or organization may receive funding for only one project.

For large institutions such as universities or city governments, schools or departments are considered separate entities. 

The Rachael and Ben Vaughan Foundation offers grants ranging from $2,000 to $20,000 for projects focused on animal rights, education, environmental preservation, poverty reduction, and religious initiatives. The foundation prioritizes local Texas projects but accepts applications from outside the state. Grants are awarded only to tax-exempt organizations, and projects should be completed within twelve months. The foundation aims to support initiatives that benefit local communities without duplicating existing efforts.

The Fred C. Gloeckner Foundation Research Fund Grant, established in 2024, supports innovative floriculture research and education. This partnership between the Gloeckner Foundation and AFE aims to enhance advancements in floriculture through substantial funding. Grants are available for university and college projects, emphasizing significant research importance and public accessibility. Projects can include funding for research assistants and must be accompanied by detailed outlines. Indirect costs and salaries are not covered.

The Rural Placemaking Grants by the Blandin Foundation aim to enhance the quality of life in the most diverse and underserved rural communities. By promoting community engagement through creative initiatives, this program seeks to foster pride and connection among residents. Grants typically range from $25,000 to $150,000, addressing projects that uplift local civic spaces and encourage participation from marginalized groups, contributing to overall community well-being and economic growth.

The Northeast Sea Grant Consortium and NOAA’s Northeast Fisheries Science Center invite proposals to explore the interactions between fishing communities and offshore wind development in the U.S. Northeast. This initiative aims to enhance understanding of community resilience and economies, while fostering collaborative research that informs decision-making. Proposals should utilize qualitative and quantitative methods and involve at least one Co-PI from the six states of the NESGC, with a requirement for a 25% non-federal match.

The Impact Aid Discretionary Construction Grant Program (84.041C) offers $19M in funding to Local Educational Agencies (LEAs) to address urgent school facility needs. This initiative supports repairs, renovations, or replacements required to maintain safe educational environments. Grants cover projects that improve accessibility in compliance with the Americans with Disabilities Act (ADA) and ensure that facilities meet health standards. The program aims to enhance learning conditions by responding effectively to emergency situations.

The FY 2023 Disaster Supplemental grant aims to support communities affected by major disasters, such as Hurricanes Ian and Fiona, by funding both construction and non-construction projects. This initiative focuses on long-term economic recovery strategies to address the challenges faced in areas with federal disaster declarations. Additionally, the Economic Development Administration has launched the Economic Development Grants Experience (EDGE) platform to enhance the efficiency and transparency of the grant management process.

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Easterby Family Scholarship ($7,000)

This renewable scholarship is for students from Laurens County, South Carolina who are pursuing graduate or post-graduate education in the fields of theology or medicine. 

The ASTR Translation Prize recognizes the vital contributions of translators in theater and performance studies. It honors an exceptional English translation of works such as plays, performance texts, scholarly books, and articles published in the last calendar year. The award includes a $500 honorarium and free registration to the annual ASTR conference, promoting the importance of translations in enhancing the global theater landscape.

The Volk – Geyman Scholarship, established by the San Juan Pilots Association, honors John Volk and John Geyman by providing financial assistance to students pursuing careers in aviation and medicine. This scholarship aims to support high school graduates with a commitment to academic excellence and community service. Eligible fields include aviation-related studies and emergency medical training. By fostering leadership and service, the scholarship encourages students to follow the inspiring examples set by its namesakes.

The ACS Congressional Fellowship Program offers trained scientists the chance to engage in the policy-making process, providing critical information to lawmakers on science-related issues. Each year, two fellows are placed in the offices of Senators, Representatives, or Committees, with the aim of educating them on how science policy is formed. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of whether they hold a doctorate.

The BJA FY 2026 Kevin and Avonte Program aims to reduce the injuries and fatalities of individuals with dementia and developmental disabilities who wander from safe environments. This funding opportunity supports law enforcement and public safety agencies in implementing locative technologies to track missing individuals and develop programs that enhance safety and facilitate rescues, ultimately ensuring the well-being of vulnerable populations.

The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.