Best Large Grants for Nonprofit Organizations in Minnesota

The McGraw Foundation offers annual grants to not-for-profit organizations, primarily in the greater Chicago area, focusing on education, conservation, and human services. Grant amounts typically range from $2,000 to $10,000, with larger grants available for particularly impactful projects. While supporting diverse initiatives, the Foundation does not fund individuals or specific events. Organizations must be tax-exempt under IRS regulations to qualify for funding. The Foundation encourages innovative approaches and partnerships in grant applications.

The MN Environmental Quality Incentives Program (EQIP) is a key conservation initiative by NRCS that supports farmers and landowners in integrating sustainable practices on their working lands. It offers technical and financial assistance to address vital resource concerns like soil health and water quality. Eligible applicants include agricultural producers and private forestland owners. This program fosters environmental stewardship while enhancing agricultural productivity, making it a valuable resource for Minnesota's agricultural community.

The AWWA Scholarship Program, specifically the Dr. Philip C. Singer Scholarship, honors a graduate student dedicated to advancing research in drinking water quality, environmental science, and public health. Established in 2020 by the American Water Works Association, this $3,000 scholarship aims to support innovative research that addresses pressing challenges in the water industry. By investing in future leaders, AWWA reinforces its commitment to ensuring safe and sustainable water for all.

The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.

The Community Ties Giving Program by Union Pacific Foundation offers local grants aimed at enhancing community well-being through diverse funding priorities. These include safety initiatives, workforce development, community vitality, and environmental sustainability. The program emphasizes supporting organizations that promote diversity, equity, and inclusion, aiming to create impactful projects that resonate with Union Pacific's heritage and mission. Eligible applicants must be nonprofit organizations serving Union Pacific communities and demonstrate a clear need and capacity to deliver effective programming.

The Development Partnership Grants, offered by the Minnesota Department of Iron Range Resources and Rehabilitation, fund initiatives aimed at fostering long-term economic growth in northeastern Minnesota. Applications are open from July 1, 2025, until May 29, 2026, or until funds are allocated. These grants support research, planning, and education projects that align with community development goals, helping to strengthen the region's economy and enhance local resources.

The Northland Foundation offers quarterly grants aimed at supporting nonprofit organizations in Northeast Minnesota and nearby Native nations. These grants provide flexible funding for general operations or specific programs that address community needs such as health, housing, and education. Eligible applicants include 501(c)(3) nonprofits, educational institutions, and local governments. The foundation prioritizes projects that promote equity, community engagement, and sustainable impact, ensuring that resources reach underserved populations.

The Vibrant & Equitable Communities Grant by The McKnight Foundation aims to foster shared prosperity in Minnesota through strategies like economic mobility, community wealth building, fair housing, and democratic participation. This grant supports organizations that enhance employment opportunities for underrepresented communities, strengthen community-focused financial institutions, and promote equitable access to housing and civic engagement. Applications are accepted on a rolling basis, with a focus on systemic improvements for individuals and communities.

Minnesota Pollution Control Agency

The Minnesota Pollution Control Agency (MPCA) is committed to ensuring that every Minnesotan has healthy air, sustainable lands, clean water, and a better climate.

Through the authority of state and federal statutes and guidelines, the MPCA focuses on preventing and reducing the pollution of air, land, and water, and leads Minnesota’s efforts to protect against the devastating effects of climate change. We work with regulated parties, businesses, governments, organizations, and 11 Tribal Nations in Minnesota to develop innovative, community-centered approaches that protect our natural resources, improve human health, and foster strong economic growth.

Minnesota GreenCorps

Serving communities for a greener tomorrow

The Minnesota GreenCorps program, coordinated by the MPCA, aims to preserve and protect Minnesota’s environment while training a new generation of environmental professionals.

Each year, the program places AmeriCorps members with host site organizations around the state to build community resilience by:

• reducing air pollutants and improving air quality
• reducing water runoff and improving water and land quality
• preventing waste and increasing recycling
• encouraging eco-friendly behavior

Minnesota GreenCorps members serve full-time at their host site for 11 months, from September to August each year. Members implement environmental projects to build community resilience in one of four topic areas: community readiness and outreach, energy conservation and green transportation, stormwater and forestry, waste reduction and recycling. Sample projects include activities such as coordinating multi-modal transportation events, educating community members and youth, removing invasive species, installing rain gardens, benchmarking energy, conducting waste sorts, and more. 

Host Sites

As a host site, your organization can harness a member's energy and enthusiasm to move your environmental projects forward. Member projects must align with one of four topic areas: community readiness and outreach, energy conservation and green transportation, stormwater and forestry, or waste reduction and recycling. Host sites don't pay a fee to participate in the program but are expected to provide supervision, office space, internet and phone service, training, and any resources necessary for members to accomplish their projects. The MPCA manages the recruitment, application, and selection process for Minnesota GreenCorps members.

The Father's Table Foundation Grant aims to glorify God by addressing the immediate and future needs of women and children globally. This selective grant process emphasizes building self-sufficiency and resilience among beneficiaries, focusing on proven partners capable of expanding their impact. The foundation supports a diverse range of projects, including employment assistance, education, humanitarian aid, and health care, ensuring that aid not only meets urgent needs but also fosters long-term sustainability.

The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.

The Emerging Global Leader Award (K43) offers essential research support and protected time for early career scientists in low- and middle-income countries. This program, aligned with NIH's clinical trials policy, aims to cultivate independent research careers by providing mentorship and funding over three to five years. Eligible candidates must hold a junior faculty position at an accredited LMIC institution, fostering the growth of research capacity in their regions.

The Cleveland-Cliffs Foundation, established in 1962, focuses on enhancing educational opportunities, environmental protection, and community health in the regions it operates. As a leading steel manufacturer, Cleveland-Cliffs is committed to sustainability and responsible corporate citizenship. The foundation supports 501(c)(3) organizations that address key challenges in education, the environment, and community well-being, ensuring impactful investments that help communities thrive across North America.

The Blandin Foundation's Community Wealth Building Grants aim to empower rural communities in Minnesota by addressing economic disparities and fostering sustainable growth. Targeting low-income, diverse populations, the grants focus on collaborative projects that enhance affordable housing, promote local businesses, and improve access to resources. With funding ranging from $25,000 to $150,000, the foundation seeks innovative solutions to strengthen community ties and support marginalized populations, ensuring a robust future for rural Minnesota.

The Best Life Community Awards, funded by Altra Foundation Inc, invites nominations for nonprofit organizations that have made a significant impact in their communities. Altra members can nominate eligible 501(c)(3) nonprofits they support with their time, talents, or financial contributions. The selected nonprofit will receive a $10,000 grant, aimed at fostering initiatives in education, health, and community services across specific counties in the U.S. Nominate today to help recognize outstanding contributions!

The Richard M. Schulze Family Foundation provides grants focused on education, human services, and health and medicine. They support high-performing educational institutions, scholarships, and nonprofits that enhance learning experiences. In human services, they assist organizations tackling hunger, shelter, and mental health issues. Their health initiatives include funding for medical research and treatment services. All support is by invitation only, ensuring that funding aligns with their mission to reduce suffering and promote community well-being.

The McKnight Foundation's Midwest Climate and Energy Grant focuses on funding initiatives that address the climate crisis while promoting equity in the Midwest. The foundation supports projects that transform energy systems, decarbonize transportation and buildings, and enhance community resilience. It aims to engage diverse populations and foster innovative solutions to reduce greenhouse gas emissions and advance sustainable practices. Eligible organizations include nonprofits, governmental entities, and those in Minnesota, Wisconsin, and Iowa, with an emphasis on collaborative, impactful projects.

The Huntington Impact Investment Philanthropy Grant Program aims to strengthen communities by supporting nonprofit organizations that enhance self-sufficiency and social equality. With a focus on areas such as community revitalization, affordable housing, and economic development, the program prioritizes initiatives that serve low- and moderate-income individuals. Organizations with IRS tax-exempt status can apply for funding to address critical community needs, fostering a more equitable environment for all.

The Fogarty Emerging Global Leader Award supports early career research scientists from low- or middle-income countries (LMIC) by providing research funding and mentored career development for three to five years. This program encourages LMIC scientists in health-related fields to develop projects aligned with their country's health priorities, fostering independent research careers within their institutions. Applications are welcomed from junior faculty members, enhancing global health research and capacity in LMICs.

The Aegon Transamerica Foundation Grant supports non-profit organizations focused on enhancing financial and social empowerment in communities where Transamerica employees live and work. Established in 2000, the foundation prioritizes initiatives that foster self-reliance, financial literacy, and community engagement. Eligible organizations must be IRS 501(c)(3) non-profits operating in specific locations such as Atlanta, GA and Denver, CO. The foundation does not fund individuals or certain types of organizations, aiming to create inclusive, resilient communities.

The Joyce Foundation's Environment Grants focus on addressing critical environmental challenges in the Great Lakes region, such as climate change and water safety. The foundation prioritizes equitable, carbon-free energy solutions and clean water access for all communities. Grants are awarded to organizations committed to environmental justice and innovation in climate policy, particularly in Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin, ensuring that the voices of affected communities guide project development.

The John Ben Snow Memorial Trust Grant supports educational programs and initiatives that assist individuals demonstrating financial need. Founded in 1975, it prioritizes funding for organizations that enhance educational opportunities, arts, culture, and community initiatives, particularly for youth and disadvantaged populations. The Trust encourages proposals from 501(c)(3) organizations, with grants typically ranging from $10,000 to $20,000. It also considers limited proposals in disabilities, environmental protection, and historic preservation, focusing on educational impact.

Biogen Corporate Sponsorships provide funding to support congresses, events, and initiatives in exchange for tangible benefits such as marketing opportunities and recognition. Applications are reviewed on a rolling basis, and requests must be submitted 50 days in advance. Biogen considers various disease areas for sponsorship, including Alzheimer’s and Multiple Sclerosis. Approval depends on funding availability, alignment with interests, and event details, ensuring transparency for all potential sponsors.

The Urban Farm Conservation Mini-Grant provides up to $5,000 to support commercial urban farmers in Minnesota in implementing vital conservation practices. Funded by the USDA's NRCS, this grant helps farmers acquire equipment and materials necessary for sustainable management of soil, water, and biodiversity. Eligible projects may include soil improvement, water management systems, and enhancing plant and animal health. This initiative aims to promote environmentally friendly farming techniques and bolster urban agriculture.

The Fred C. & Katherine B. Andersen Foundation Grant focuses on enhancing the quality of life in the St. Croix Valley of Minnesota and Wisconsin. It supports 501(c)(3) nonprofit organizations with priorities in healthcare, education, housing, human services, civic initiatives, and environmental education. While capital requests may be considered, the foundation primarily funds operational and programmatic needs. Organizations outside the geographic area may be considered if they align with the foundation's funding priorities.

The Clif Family Foundation Open Call invites 501(c)(3) organizations to apply for grants supporting general operating costs or specific projects. With a focus on regenerative farming, food worker health, climate justice, and food access, the foundation aims to empower grassroots initiatives. Grants range from $5,000 to $50,000, with applications reviewed twice a year. Deadlines are March 1 and August 1, and announcements occur about four months post-deadline.

The Sustaining Environmental Systems Grant aims to ensure equitable access to healthy land and water for all Minnesotans. The Mortenson Family Foundation supports community-led environmental solutions and multi-year grants to partner organizations. It prioritizes partnerships that focus on sustainability, racial justice, and community engagement, fostering innovative approaches to restore relationships with nature and address climate change impacts. The foundation seeks organizations that can deliver tangible environmental outcomes while empowering historically marginalized communities.