Best Operating Grants for Nonprofits in Minnesota

Geological Society of America 

The Geological Society of America (GSA), founded in 1888, is a global scientific society with members from academia, government, and industry in more than 100 countries. Through its meetings, publications, and programs, GSA enhances the professional growth of geoscientists at all career levels, encourages cooperative research among earth, life, planetary, and social scientists, fosters public dialogue on geoscience issues, and promotes the geosciences in the service of humankind. GSA is headquartered in Boulder, Colorado, USA.

Jack Kleinman Memorial Award for Volcano Research

The Jack Kleinman Memorial Award for Volcano Research represents a partnership between GSA and the U.S. Geological Survey (USGS) to recognize early-career scientists conducting high-impact research in volcanology. The award was created in memory of Jack Kleinman—a USGS Cascades Volcano Observatory scientist known for his commitment to collecting high-quality field data and who relished a challenge, inspired enthusiasm in others, and delighted in the natural world. The award honors students who demonstrate these same qualities in their scientific explorations.

Up to US$5,000 may be awarded to undergraduate, graduate, and aspiring graduate students, regardless of current enrollment status. Successful proposals typically focus on geologic, geochemical, geophysical, or hazards investigations with an emphasis on fieldwork. Cooperation with a staff member from the USGS Volcano Science Center is encouraged and given considerable weight in the selection process.

Funding is intended to defray the costs of field-focused studies, such as travel to field sites, living expenses during fieldwork, field supplies, and analytical costs. Awardees are invited to present their results in the USGS Kleinman Seminar Series and attend the Awards Ceremony at the GSA annual meeting.

The FY26 Breast Cancer Research Program's Transformative Breast Cancer Consortium Award fosters significant collaborations that aim to revolutionize care for individuals affected by breast cancer. This award supports a multidisciplinary consortium of leading scientists, clinicians, and advocates to tackle major challenges in breast cancer research. Proposals must address at least one of the program's overarching challenges and demonstrate a transformative impact that cannot be achieved by individual investigators alone.

The DoW Ovarian Cancer Pilot Award fosters innovative research that challenges existing paradigms in ovarian cancer. It aims to propel groundbreaking discoveries and advancements in the field. Notably, the award prioritizes originality over scientific merit alone, ensuring that innovative ideas are at the forefront. The application process includes a blinded pre-application screening to maintain confidentiality and integrity, encouraging fresh perspectives in ovarian cancer research.

The Prader-Willi Syndrome Mini-Fellowship Grant aims to enhance understanding of Prader-Willi Syndrome (PWS) through clinical proctorships. Offering up to $25,000 USD, this grant supports providers in shadowing experts in PWS while engaging in an academic project. PWSA | USA, dedicated to advancing research since 1983, focuses on high-impact projects that translate biomedical knowledge into effective treatments, ultimately improving the lives of those affected by PWS.

The Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award aims to support impactful research addressing critical needs in ovarian cancer and patient care. It requires a robust research plan with preliminary data and allows for studies across all research phases, excluding clinical trials. A unique Partnering Principal Investigator option encourages collaboration between two PIs to enhance research outcomes beyond individual efforts, promoting innovation in the field of ovarian cancer.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 3 supports transformative research aimed at significant advancements in breast cancer treatment. Applicants must address key challenges outlined by the program, ensuring their proposals demonstrate potential for impactful breakthroughs. This funding mechanism, which permits small-scale clinical trials, emphasizes collaboration by requiring research teams to include two breast cancer consumer advocates and allows for a single Principal Investigator or two partnering PIs.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Paul and Libby Kara Scholarship

This scholarship has been made possible by the generosity of Paul M. Kara, who established the Paul and Libby Kara Scholarship of the Community Foundation for Muskegon County. The Paul and Libby Kara Scholarship Fund helps graduating seniors or adult/returning students with significant financial need. It is designed to help students with the "last dollars" needed to continue their education. Paul and Libby believe that every student should be able to achieve their educational goals.

The DoW Ovarian Cancer Clinical Trial Award, funded by the U.S. Army Medical Command, aims to accelerate the implementation of clinical trials that significantly impact ovarian cancer treatment. This award supports diverse trial designs, from early proof-of-concept studies to large-scale efficacy trials, evaluating innovative drugs, biologics, and technologies. By fostering research in this critical area, the program seeks to enhance patient outcomes and advance the understanding of ovarian cancer management.

The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.

The OAR Community Grant aims to enhance the quality of life for autistic individuals by funding community-led projects that address physical health and support services. Grants ranging from $1,000 to $15,000 are available for initiatives designed to produce practical tools and resources. Eligible applicants include family members, autistic individuals, and community organizations committed to improving the lives of those affected by autism. Projects should be innovative, publicly accessible, and focus on priority topics such as health systems and community services.

The DoW Ovarian Cancer Academy Early-Career Investigator Award supports junior faculty in conducting innovative ovarian cancer research. Established in FY09, this unique virtual academy fosters mentorship, collaboration, and networking among Early-Career Investigators (ECIs) and their mentors. Participants engage in monthly webinars and annual workshops, enhancing their research skills while contributing to impactful studies in ovarian cancer. The program aims to cultivate a new generation of highly productive researchers in this critical field.

Access Advocate for Clinical Research Participation

Objective:

This program will support implementation and evaluation of a Parkinson’s disease (PD) focused Access Advocate model designed to increase inclusive research participation. Funding will support Access Advocates at clinical sites to build practical, relationship based pathways to improving representative research enrollment and retention.

Funding Details:

• Duration: 24 months 
• Award Amount: $200,000 

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and its inclusive recruitment strategy has examined what barriers and motivators shape participation (e.g., FIRE-UP PD study3) as well as funded sites to pilot tactics that address those barriers (e.g., Black & African American Connections to Parkinson’s Disease study4). Now we aim to scale and validate approaches that show early promise by investing more deeply and measuring impact across settings.

This program will fund advocates at clinical sites to build practical, relationship-based pathways to improving representative research enrollment and retention. These support staff will help patients and care partners navigate health system complexity and everyday needs that often determine whether research participation is feasible. They will help address barriers such as transportation, caregiving responsibilities, language needs, and insurance and financial strains by connecting people to resources, coordinating logistics and providing consistent follow-up. These advocates also should discuss research participation opportunities with patients and connect them to recruiting studies.

The model is grounded in the idea that research participation is more feasible when (i) foundational practical needs are addressed first and (ii) raised by a trusted health care partner. By helping to reduce practical barriers, advocates are expected to increase screenings, enrollment conversion and retention across key trial milestones.

This program will test these hypotheses and further establish training, infrastructure needs and sustainability of such positions.

Program Goal

This program aims to:

• Support establishment of site-based Access Advocates to support potential participants and care partners across multiple active or planned PD studies.
• Evaluate needs and opportunities for onboarding and ongoing training for advocates in PD and clinical research fundamentals as well as site and local resources.
• Recommend repeatable workflows for identifying prospective participants, assessing barriers, connecting them to resources, coordinating logistics and supporting follow-up.
• Collect and report a core set of evaluation metrics across sites (reach, encounters, referrals, screened, enrolled, retained), including barrier tracking and resolution.
• Evaluate the impact of Access Advocates in recruiting and retaining underrepresented community individuals to/in Parkinson’s studies.
• Evaluate the impact of Access Advocates on “health system value” indicators (e.g., appointment adherence/show rates, medication access/adherence proxies) that could support funding sustainability from other sources.
• Establish a cross-site learning community that enables funded sites to share lessons, refine the Access Advocate model and inform broader adoption beyond the funding period.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 4 supports innovative research with the potential for significant breakthroughs in breast cancer. Applications must address key BCRP challenges or justify exceptions, focusing on impactful solutions. This program mandates clinical trials and requires participation from breast cancer consumer advocates. The funding supports single or partnered Principal Investigators, ensuring comprehensive submission processes to avoid administrative withdrawal.

Hennepin County's Well Sealing Cost Share Grant Program provides funding for property owners to seal unused wells that threaten groundwater. Grants cover up to 75% of sealing costs, with a maximum reimbursement of $2,000 per well. Eligibility requires wells to be in designated protection areas, while properties listed for sale are excluded. A 25% cash match is required from applicants. This initiative aims to safeguard drinking water resources and promote environmental stewardship.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

In God We Trust, Mitchelle T. Savage Memorial Scholarship Fund

The In God We Trust, Mitchelle T. Savage Memorial Scholarship was established to provide educational opportunities beyond high school for Battle Creek area graduates or graduating seniors. Eligible recipients will be graduating seniors from Battle Creek area public and private schools who will be attending a college that is a member of the Council for Christian Colleges and Universities.

The Whole Foods Market Store Giving Program supports local communities by providing financial assistance to 501(c)(3) nonprofit organizations that focus on food access and environmental stewardship. This biannual program allows eligible organizations to apply via the Community Engagement Portal, although not all requests can be fulfilled due to high demand. Priority is given to those without recent funding, promoting sustainable community engagement.

The Washington Tree Fruit Research Commission is inviting research proposals aimed at apple crop protection, emphasizing organic practices and pollinator protection. Key areas of focus include the management of pests like Codling Moth and Fire Blight, testing new crop protection products, enhancing soil health, and developing efficient monitoring techniques. Collaboration among institutions is encouraged, and projects should aim for practical industry applications to ensure sustainable and profitable tree fruit production.

The National Cancer Institute (NCI) seeks to enhance the validation of biomarkers and assays for cancer detection and treatment through its UH3 funding mechanism. This initiative supports multi-disciplinary collaborations to validate existing assays over three years using clinical trial specimens. Emphasis is placed on harmonizing laboratory tests and validating pharmacodynamic markers. Projects should not focus on early-stage technology development but aim for integration into clinical studies as investigational assays.

Devinci's Community Grant Program aims to support North American cycling organizations with financial assistance for development projects. Eligible applicants include cycling clubs, non-profits, and individuals leading community initiatives. Projects must occur in Canada or the U.S. within the year, with a maximum grant of $5,000 CAD. The program collaborates with key industry partners to foster growth in the cycling community, making a lasting impact through local initiatives.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

About The Children’s Heart Foundation

The Children’s Heart Foundation (CHF) is the country’s leading national organization solely dedicated to funding congenital heart defect (CHD) research. The mission of The Children’s Heart Foundation is to fund the most promising research to advance the diagnosis, treatment, and prevention of congenital heart defects. Since its inception, CHF has funded millions of dollars of CHD research across the U.S. and Canada. 

AHA/CHF Congenital Heart Defect Research Awards

The Children’s Heart Foundation partners with the American Heart Association to fund Congenital Heart Defect Research Awards. This collaborative investment of funds provides support for investigators who are actively conducting research directly related to advancing the prevention, diagnosis, and treatment of CHDs, which directly aligns with The Children's Heart Foundation's mission. 

Congenital Heart Defect Funding Opportunities

A multi-year commitment between the American Heart Association (AHA) and Children’s Heart Foundation (CHF) jointly supports Predoctoral Fellowship or Postdoctoral Fellowship investigators actively conducting basic, clinical, population, or translational congenital heart defects research.

Postdoctoral Fellowship

Purpose

To enhance the training of postdoctoral applicants who are not yet independent. The applicant must be embedded in an appropriate investigative group with the mentorship, support, and relevant scientific guidance of a research mentor. Recognizing the unique challenges that clinicians, in particular, experience in balancing research and clinical activity, this award mechanism aims to be as flexible as possible to enable applicants to develop academic careers in research alongside fulfilling clinical service commitments.

The trainee and mentor should collaboratively provide a thoughtfully planned, systematic proposal aimed at clearly answering an investigative question in cardiovascular, cerebrovascular or brain health research

• AHA research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals andothers that can demonstrate the ability to conduct the proposed research.

• Applicants must be AHA Professional Members at the time of proposal submission. The AHA expects all mentors associated with training/mentored research awards to maintain active AHA membership, as well.

• This award is not intended for individuals of faculty rank.

Applicants are not required to reside in the United States for any period before applying for American Heart Association funding. However, applicants must have one of the following designations at the time of proposal submission – not award start date, depending on career stage and each individual’s situation. An awardee must maintain one of the designations listed below throughout the duration of the award. Please consult with your institution’s grant officer.

• U.S. citizen
• Permanent resident
• Pending permanent resident (must have filed Form I-485 for permanent resident status and obtained an I-797C 3 Notice of Action that the application has been received by USCIS and case is pending)
• E-3 Visa - specialty occupation worker
• F-1 Visa – student (for predoctoral and postdoctoral fellows only)
• G-4 Visa - family member of an international organization employee
• H1-B Visa - temporary worker in a specialty occupation
• J-1 Visa - exchange visitor (pre- and postdoctoral fellowships only; all other awardees must obtain an H-1B or equivalent by the award activation date)
• O-1 Visa - temporary worker with extraordinary abilities in the sciences
• TN Visa - NAFTA Professional
• DACA - Deferred Action for Childhood Arrivals

The National Scleroderma Foundation's New Investigator Grant aims to support emerging researchers dedicated to scleroderma studies. This three-year grant, totaling $200,000, encourages applicants with doctoral degrees and postdoctoral experience. Eligible candidates are invited to submit proposals that may lead to further research funding. The grant emphasizes innovative research approaches while providing essential financial support for early-career investigators. Note that the grant does not cover certain costs, ensuring focused investment in research advancement.

The Early Literacy Grants by the Southern Minnesota Initiative Foundation aim to enhance school readiness for children from birth to age eight by providing access to books. This program encourages organizations working with young children to apply for funding to distribute books to families, fostering a love for reading at an early age. Partnerships with local publishing companies ensure a steady supply of quality reading materials, with book pickups scheduled for June in Owatonna.

The Southern Minnesota Initiative Foundation (SMIF) will offer Economic Development Grants starting in Fall 2025. These grants aim to enhance local economies by supporting initiatives in entrepreneurship and community development within a 20-county region. Eligible applicants include IRS-designated 501(c)(3) nonprofits and public institutions in SMIF's area. Grants of up to $20,000 will be available, making it a valuable opportunity for organizations focused on economic growth.

The ChemClub Student Scholarship, offered by the American Chemical Society and the American Association of Chemistry Teachers, supports high school seniors who are active members of a Chartered ChemClub. Eligible students must demonstrate academic excellence and express their commitment to STEM fields. This scholarship provides financial assistance directly to the recipient's chosen college, fostering future leaders in chemistry and related disciplines.

EmpowHer Grants, offered by the Boundless Futures Foundation, provide essential financial support and resources to female entrepreneurs in the U.S. who are committed to creating social impact through their businesses. Grants, which can go up to $25,000, are available to those with businesses that are less than three years old and demonstrate revenue generation. This initiative aims to empower women by reducing barriers and fostering a supportive entrepreneurial community.

About The Children’s Heart Foundation

The Children’s Heart Foundation (CHF) is the country’s leading national organization solely dedicated to funding congenital heart defect (CHD) research. The mission of The Children’s Heart Foundation is to fund the most promising research to advance the diagnosis, treatment, and prevention of congenital heart defects. Since its inception, CHF has funded millions of dollars of CHD research across the U.S. and Canada. 

AHA/CHF Congenital Heart Defect Research Awards

The Children’s Heart Foundation partners with the American Heart Association to fund Congenital Heart Defect Research Awards. This collaborative investment of funds provides support for investigators who are actively conducting research directly related to advancing the prevention, diagnosis, and treatment of CHDs, which directly aligns with The Children's Heart Foundation's mission. 

Congenital Heart Defect Funding Opportunities

A multi-year commitment between the American Heart Association (AHA) and Children’s Heart Foundation (CHF) jointly supports Predoctoral Fellowship or Postdoctoral Fellowship investigators actively conducting basic, clinical, population, or translational congenital heart defects research.

Predoctoral Fellowship

Purpose

To enhance the integrated research and clinical training of promising students who are matriculated in pre-doctoral or clinical health professional degree training programs and who intend careers as scientists, physician-scientists or other clinician-scientists, or related careers aimed at improving global cardiovascular, cerebrovascular and brain health.

• AHA research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals and others that can demonstrate the ability to conduct the proposed research.

• Applicants must be AHA Professional Members at the time of proposal submission. The AHA expects all mentors associated with training/mentored research awards to maintain active AHA membership, as well.

• This award is not for individuals of faculty/staff rank.

Applicants are not required to reside in the United States for any period before applying for American Heart Association funding. However, applicants must have one of the following designations at the time of proposal submission – not award start date, depending on career stage and each individual’s situation. An awardee must maintain one of the designations listed below throughout the duration of the award. Please consult with your institution’s grant officer.

• U.S. citizen
• Permanent resident
• Pending permanent resident (must have filed Form I-485 for permanent resident status and obtained an I-797C 3 Notice of Action that the application has been received by USCIS and case is pending)
• E-3 Visa - specialty occupation worker
• F-1 Visa – student (for predoctoral and postdoctoral fellows only)
• G-4 Visa - family member of an international organization employee
• H1-B Visa - temporary worker in a specialty occupation
• J-1 Visa - exchange visitor (pre- and postdoctoral fellowships only; all other awardees must obtain an H-1B or equivalent by the award activation date)
• O-1 Visa - temporary worker with extraordinary abilities in the sciences
• TN Visa - NAFTA Professional
• DACA - Deferred Action for Childhood Arrivals