Best Large Grants for Nonprofit Organizations in New York

The Aaaron Ardoin Foundation offers Research and Education Grants aimed at supporting organizations that address the needs of individuals and families affected by sickle cell disease. With a focus on funding programs that advance awareness, treatment, and care, the foundation reviews grant requests biannually. Eligible applicants must be 501(c)(3) organizations dedicated to initiatives directly benefiting the sickle cell community, ensuring that funds are utilized efficiently and effectively.

Wichita Falls Area Community Foundation

For over 25 years, the Community Foundation has remained committed to leaving a legacy for future generations by promoting philanthropy, providing charitable opportunities, and facilitating donors’ interests. We work alongside donors and community partners to help meet area needs, create solutions, and inspire action to build a vibrant community today and a stronger community for tomorrow. 

Scholarships

The Community Foundation is home to 50 scholarship funds established by generous individuals, organizations and businesses to help students from our community and surrounding areas pursue their dreams through education. 

Bill Mahoney Memorial Scholarship

The Bill Mahoney Memorial Scholarship was opened in 2021 by Bill's daughter, Mandy, to honor her father's memory. Mr. Mahoney was a long-time teacher of the Arts at Hirschi High School in Wichita Falls. This one-time scholarship, ranging from $1,000 to $4,000, is for graduating seniors of WFISD attending any college, university, or vocational school and majoring in the Arts. Recipient must be a U.S. citizen.

The ACS Professor Award, presented by the American Cancer Society, recognizes full professors who have significantly advanced cancer research. This honorific award aims to support innovative pursuits in cancer research with a budget of up to $80,000 per year for five years. Applicants are expected to demonstrate impactful contributions and leadership in the field, along with a commitment to mentorship and community engagement. The award highlights the importance of ongoing advocacy and research in improving cancer treatment and prevention.

The US Department of Health & Human Services, through the FDA, is offering a $1.5 million cooperative agreement for a non-profit to establish the Integrated Food Safety System Regulatory and Laboratory Training System National Coordination Center. This center will oversee the training system, enhancing access to high-quality regulatory and laboratory learning resources for both human and animal food safety, thereby leveraging partnerships to improve food safety training nationwide.

The Brown Rudnick Community Grants program aims to support front-line educational workers in underserved communities across cities like Boston and New York. With grants up to $2,000, it addresses immediate educational needs that traditional funding overlooks. This initiative encourages collaboration with educators to enhance learning environments and foster positive change, ensuring that impactful projects receive the necessary support to thrive within a year of funding.

The Terry Farrell Firefighters’ Fund, established post-9/11, provides vital educational and financial support to families of firefighters across the U.S. With over $10 million distributed in grants and surplus gear, the fund offers scholarships, emergency assistance, and training for first responders. It also supplies rural fire departments with necessary equipment and sponsors health initiatives like blood and bone marrow drives, ensuring comprehensive support for those who serve our communities.

The Animal Food Regulatory Program Standards Implementation Development and Maintenance initiative aims to enhance the national animal food safety system. This funding opportunity supports state regulatory programs in achieving and sustaining the Animal Food Regulatory Program Standards (AFRPS) within five years. By fostering collaboration with the FDA and standardizing regulatory processes, this initiative seeks to improve food safety, promote compliance, and mitigate foodborne illnesses, ultimately creating a more integrated food safety framework.

Lester Educational Fund

Fund provides scholarships to help students obtain an education in a profession or vocation.

Amount

$1,000+

The Citizens Philanthropic Foundation Grant for Financial Empowerment supports nonprofit organizations focused on providing financial education to low- and moderate-income individuals. The foundation prioritizes projects that demonstrate measurable impact, particularly those serving diverse populations in NJ and Metro New York. Eligible applicants must be IRS-qualified 501(c)(3) organizations and align their proposals with the foundation's goals of fostering financial literacy and collaboration with Citizens colleagues.

The Citizens Grants: Financial Empowerment program supports nonprofits focused on creating measurable impacts in financial education for low to moderate income individuals and small businesses. This grant emphasizes partnerships with established 501(c)(3) organizations and encourages collaborative efforts that demonstrate alignment with funding priorities. By investing in financial literacy, Citizens aims to enhance fiscal health in underserved communities across select geographic areas.

The Research With Activities Related to Diversity (ReWARD) program by the NIH aims to enhance research diversity and inclusion across the United States. It supports scientists contributing to Diversity, Equity, Inclusion, and Accessibility (DEIA) who lack current NIH funding. The program funds both scientific research and DEIA activities, addressing the needs of various NIH Institutes and Centers to foster a more diverse biomedical research landscape.

The Jessie Smith Darrah Fund is dedicated to supporting charitable, educational, and social initiatives primarily in Chautauqua County. With a funding range of $1,000 to $200,000, the fund prioritizes organizations like the First Methodist Church of Jamestown and the YMCA. Eligible applicants must hold 501(c)(3) status, promoting human welfare and good citizenship through various community projects.

The Whitehall Foundation's Grants-in-Aid program supports early-career researchers in the life sciences, specifically in neurobiology. Aimed at assistant professors facing funding challenges, grants do not exceed $30,000 for one year. Applications are evaluated based on scientific merit and innovation. Eligibility requires independence as an investigator and Principal Investigator status. This program fosters research in areas underrepresented by federal funding, highlighting the Foundation's commitment to advancing biological research and supporting young scientists.

The AO North America: Young Investigator Research Development Award supports research initiatives for orthopedic trauma fellows in their first year post-fellowship. With a maximum funding of $30,000, the award facilitates professional growth through periodic reporting and networking. Eligible applicants must be fellows in an AO-supported program and current members of AO Trauma, ensuring a commitment to excellence in patient care and outcomes in the field of orthopedic trauma.

The Phoebe Apperson Hearst Awards honor excellence in family engagement by recognizing PTAs that achieve top rankings through the National PTA School of Excellence program. These awards celebrate PTAs that effectively engage families in student success and school improvement initiatives. By participating, PTAs can develop best practices, create inclusive communities, attract action-oriented members, and gain national recognition as leaders in building strong family-school partnerships.

The Visionary Prize for Women’s Economic Empowerment, established in 2022 by Visionary Women and the Hostetler/Wrigley Foundation, honors a visionary woman leader of a nonprofit focused on advancing women's economic empowerment in the U.S. This prestigious award provides $100,000 in unrestricted funds to support the recipient's agency and its initiatives. Eligible candidates must have a minimum of four years of operation and an annual budget exceeding $500,000, actively working towards women's economic advancement.

The Truth Initiative Tobacco/Vape-Free College Program offers grants of up to $20,000 to U.S. colleges and universities aiming to implement 100% tobacco/vape-free policies. Additionally, grants of up to $10,000 are available for schools looking to enhance existing smoke-free policies to include e-cigarettes. This initiative seeks to engage students and create support from faculty and staff, ultimately fostering healthier campus environments.

The Indian Land Tenure Foundation (ILTF) offers a Cultural Awareness Grant aimed at revitalizing the cultural and spiritual values related to Indian land. This initiative supports American Indian nations in enhancing their ties to the land, which is vital for traditional practices and beliefs. Eligible entities include tribal governments and 501(c)(3) nonprofit organizations. Ineligible activities encompass advocacy efforts, land purchases, and direct funding to individuals, ensuring resources focus on community-centered cultural preservation.

The Henry Hanff Fellowship Award offers a unique opportunity for practicing North American trauma surgeons to enhance their skills through a short-term fellowship at a trauma clinic in North America or Europe. Sponsored by AO North America, the fellowship lasts four to eight weeks and covers airfare and a stipend for living expenses, with a total award not exceeding $5,900. Participants must submit a report on their experience for publication, enhancing professional development and collaboration.

The Community Partnership Grant, administered by the Sons of Norway Foundation, offers up to $5,000 for projects that promote and preserve Norwegian culture and heritage. Open to individuals and groups from Norway and the U.S., the grant encourages initiatives that reflect the foundation's core values such as lifelong learning and community generosity. Applications must be submitted online in English and should demonstrate a commitment to celebrating Norwegian cultural traditions.

The SCI Research on the Translational Spectrum (SCIRTS) portfolio aims to promote innovative research that enhances function and alleviates complications following spinal cord injuries. It encourages studies that involve individuals with SCI, emphasizing translational significance in research designs. SCIRTS grants support diverse research areas, including mechanistic, preclinical, and clinical studies, to develop effective interventions. Funding categories include Postdoctoral Fellowships, Pilot Research Grants, and Senior Research Grants, targeting early-career and senior investigators to advance spinal cord injury research.

The George L. Mosse Prize, awarded by the American Historical Association, honors exceptional works in European intellectual and cultural history since 1500. This prestigious award, with a prize amount of $1,000, recognizes scholarly distinction and originality. Eligible submissions include books published in 2024, with a focus on research accuracy and literary merit. Winners will be announced on the AHA website in October 2025 and celebrated at the January 2026 AHA annual meeting in Chicago.

Tenney Family Scholarship

Anyone who has pondered how to leave a legacy needs to talk with Georgia Tenney.

It’s no secret that a good chunk of Georgia’s heart is entwined in Whitko Schools. A lifelong Pierceton resident, she spent over 30 years as the Middle School Secretary and is currently serving her third term as an elected school board member. Her Wildcat spirt was shared with her late husband Bob who retired as a custodian for the schools system. Together they cheered on Whitko sports until he could no longer attend games.

When Bob passed in January of this year, a couple of teachers approached Georgia with the idea of establishing a scholarship fund to which the Whitko community can contribute. Georgia put those thoughts into action and contacted the Community Foundation of Whitley County to help her fulfill a dream. It has taken shape in the form of an endowed scholarship that will benefit Whitko grads for generations to come. 

“I have always felt very fortunate in what I have been given and have long wanted to find a way to give back. After Bob passed, I told myself it was time to put a scholarship in place.” In addition to wanting to help local students achieve their educational and career goals, Georgia wanted to share a legacy of charitable giving with her children, grandchildren and great-grandchildren. “I want this to be something of which they can all be proud,” she reflected.

Anthony Wunderle Memorial Scholarship Fund

Established by Lori and Greg Wunderle in memory of their son Anthony who had childhood leukemia. This scholarship is to provide educational opportunities for a higher education, accredited trade, or apprenticeship program for any cancer survivor or family member of a cancer patient, living or deceased.

Amount:

• Varies

Number of awards:

• Varies

Renewal:

• No

The Community Foundation of Hancock County offers educational support for Hancock County, Indiana adults who are seeking post-secondary training or schooling to improve their career prospects. There are also some opportunities provided by specific businesses in the area. The application is open year-round until all funds are used.

Adult Re-Education Fund

Established by John and Linda Zimmermann, this scholarship provides support to adults who wish to obtain additional education and/or training in order to increase employment opportunities.

The Community Foundation of Marquette County distributes over $130,000 annually in scholarships to benefit aspiring students in Marquette County.

Naval Mobile Construction Battalion 25 Memorial Scholarship

Provides financial assistance for children (who are seeking post-secondary education) of members who have died while actively serving with NMCB 25. 

Distribution Process

• CFMC scholarship recipients will be contacted in June requesting student enrollment verification
• Scholarships can only be distributed once student’s information is received
• Scholarships will be distributed to the college/school/university indicated by student
• The scholarship must be used for tuition and fees required for the enrollment or attendance of the student at a qualifying educational institution; fees, books, supplies, and equipment required for courses of instruction at such an educational institution; and room and board, within the first semester of first year of students enrollment
• That year’s recipient must claim the scholarship within that fiscal year to be distributed (by 12/31/xx)

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Danny McCarty Memorial Scholarship

This scholarship has been made possible by the generosity of the Family of Danny McCarty, who established the Danny McCarty Memorial Scholarship of the Community Foundation for Mason County. Deb Del Zoppo and her family established a scholarship in memory of her nephew, Danny McCarty, after he passed away at the age of 26 in a motorcycle accident in Colorado. Danny was involved in the construction trades, so the focus of the two-year scholarship ($500 each year) is to support students who are going into that field of study.