Best Large Grants for Nonprofit Organizations in New York

The Reading is Fundamental Matching Grant - Books for Ownership program supports local literacy initiatives by providing funding for diverse books and literacy resources. Established in 1966, RIF aims to foster a culture of literacy among children in under-resourced communities. Eligible organizations can apply for funding to double their impact through matched funds, ensuring children have access to high-quality books that reflect their experiences and broaden their perspectives.

The Reading is Fundamental Matching Grant for Read for Success empowers local organizations to enhance literacy by providing matching funds for books and resources. Since 1966, RIF has partnered with communities to foster a culture of reading among children in need, offering diverse books that reflect their lives. This grant matches local investments dollar-for-dollar, maximizing the impact of funding for educational programs. Eligible applicants include schools and youth-serving organizations across the U.S., supporting children from birth through grade 12.

EEF Undergraduate College Scholarship

These scholarships are awarded to college students to support their programs in environmentally-related fields of study. Prior EEF HS winners are encouraged to apply for continued financial support.

The EEF Undergraduate College scholarship award can be as much as $4,000 for a student's sophomore, junior, or senior year. The Foundation generally awards four Undergraduate College Scholarships each year.​ These scholarships were established to benefit students from the Geneva Lake area.

The BRAIN Initiative's funding opportunity aims to support the establishment of facilities at minority-serving and IDeA-eligible institutions for the production and distribution of brain cell type-specific reagents. These reagents will enhance neuroscience research by enabling precise manipulation and access to brain cell types, facilitating advancements in understanding circuit functions in various species. The initiative encourages collaboration among awardees to optimize the use of these essential resources across the neuroscience community.

The Rural Health Fellows Leadership Program, offered by the National Rural Health Association (NRHA), is an intensive yearlong initiative aimed at cultivating a diverse network of rural health leaders. Selected participants engage in leadership training, policy advocacy, and collaborative projects. The program includes monthly virtual sessions, in-person meetings at key conferences, and opportunities for financial support, thereby empowering fellows to make a significant impact on rural healthcare.

The Fund for Excellence in Education Grants provides funding opportunities for classroom teachers in Dutchess, Putnam, and Ulster Counties. It supports special projects and professional development that enhance classroom learning and educational outcomes. Grants are available for various initiatives, including writing and STEM programs. Eligible applicants include all K-12 teachers in licensed and certified schools across these counties, ensuring a broad impact on educational quality.

The LPGA Foundation

The LPGA Foundation supports women and young people through programs and initiatives aimed at empowering them through the game of golf. Since its founding, The LPGA Foundation has touched more than 500,000 lives through various scholarship and financial assistance programs, along with its flagship junior golf program, LPGA*USGA Girls Golf. The LPGA Foundation was established in 1991 and is a non-profit 501(c)(3) charitable organization, which supports junior golf programs, scholarships, and financial assistance programs for women and young ladies.

Dolores Hope Financial Assistance Initiative

The LPGA Foundation has a tradition of taking care of its members and others in the golf industry. The Financial Assistance Fund was renamed the Dolores Hope LPGA Financial Assistance Initiative in 2007 to acknowledge Hope’s generous support of the fund and her long-time friendship with the LPGA.

The James McKeen Cattell Sabbatical Grant, provided by the James McKeen Cattell Fund, offers supplementary financial support for psychologists' sabbaticals. This grant is designed for faculty members at U.S. and Canadian institutions who meet specific eligibility criteria, including tenure status and recent leave history. The maximum award is capped at $40,000 or half the recipient's salary, ensuring that recipients can extend their research time effectively.

The scholarships we award vary each year based on the unique criteria of each scholarship. In 2025, we awarded over $3 million in scholarships to over 500 students, including $1.3 million to 110 students in western NC through our Disaster Relief and Resilience Scholarship.

Depending on the scholarship, it may pay for tuition, room and board, books, fees and/or other related educational expenses. 

Fred M. Parrish, Jr. Scholarship Endowment Fund

Graduating high school seniors from public high schools in Johnston County who are continuing their studies at an accredited college, university, community college or technical school. The Scholarship committee shall have the power to make recommendations to the Foundation as to deserving individual recipients and appropriate scholarship amounts, based on academic performance and on financial need.

This will be outlined in your award notification. The minimum scholarship award amount is $1,000.

NCCF scholarship awards are only issued to not-for-profit institutions and government entities such as public colleges or universities.

EverGreen Dreams

“Empowering young Black women to achieve educational excellence and unlock their limitless potential.”

Today, EverGreen Dreams is a community rooted in hope, equity, and empowerment. Our work centers on providing the resources, mentorship, and opportunities Black women need to thrive. We believe education is more than a pathway to success—it’s a tool for liberation and a foundation for transformation. By investing in the education and development of Black women, we’re dismantling systemic barriers and planting seeds of possibility that will grow for generations.

Building Opportunities for Sistas to Shine (B.O.S.S.) Scholarship

Introduction

Black women navigate systemic barriers in education and the workplace every day. EverGreen Dreams exists to change that narrative. As an organization founded by a Black woman and championed by advocates deeply rooted in our communities, we're committed to creating pathways to success for the next generation of Black female scholars. Through the Building Opportunities for Sistas to Shine (B.O.S.S.) Scholarship, we provide financial support to two graduating high school seniors, awarding each at least $1,000 to help them pursue their educational dreams with one less obstacle in their way.

Description

The Building Opportunities for Sistas to Shine Scholarship (B.O.S.S.) aims to make racial equality a reality by helping outstanding Black cis or transgendered women high school students achieve their dreams to continue their education. 

The ACS - Fanconi Cancer Foundation Discovery Boost Grant invites innovative proposals for translational cancer research addressing the challenges faced by individuals with Fanconi anemia (FA). This grant supports high-risk, high-reward projects aimed at improving detection, prevention, or treatment of FA-related cancers. With funding of up to $135,000 per year for two years, it encourages research in early detection technologies, prevention mechanisms, and therapeutic strategies tailored to the unique sensitivities of the FA population.

The R A Bowen Trust Scholarship, established in 1943 by Mr. Robert A. Bowen, Sr., supports deserving students from central Georgia pursuing higher education. This private scholarship aims to empower full-time students accepted into accredited four-year colleges or universities. Eligible candidates must reside in specific Georgia counties or plan to attend select institutions in Macon, GA. The Trust has a strong legacy of generosity, continuing to benefit local nonprofits and students for over four generations.

Arnold Ventures invites proposals for randomized controlled trials (RCTs) to evaluate social programs and policies. Focused on evidence-based solutions, this RFP aims to fund rigorous research that identifies effective interventions for pressing social issues. By supporting RCTs, Arnold Ventures seeks to enhance the understanding of what works in policy implementation, thereby informing decision-makers and improving resource allocation. Proposals exceeding $500,000 may require additional approval time.

The Brookreson Trust Grant aims to support financing homes for the blind and organizations that assist them. This grant is targeted towards 501(c)(3) exempt organizations across all states. The program focuses on key areas such as education, health, and human services, ensuring that vital resources are directed towards enhancing the quality of life for the visually impaired community. Grants are specifically intended for initiatives that facilitate housing and support services.

The Jim Henson Foundation offers annual grants for innovative contemporary puppet theater works, with three categories: Workshop Grants ($3,000), Production Grants ($7,000), and Family Grants ($4,000). These grants support puppet creation and performance, encouraging artistic excellence. Eligibility is primarily for IRS tax-exempt organizations, with individual artists needing a fiscal sponsor. International collaborations are welcome if the primary artist is a U.S. citizen. Grants are not available for projects based outside the U.S. or for non-puppet related activities.

The NICHD Resource Program Grants in Bioinformatics aim to support the operation and enhancement of vital bioinformatics databases for research on animal models of embryonic development. These grants promote user training, data curation, and interoperability with NIH resources, ensuring wide dissemination of critical tools and resources to the research community. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the proposal deadline.

The Women’s Shelters Grant, provided by the AKC Humane Fund, offers financial assistance to domestic abuse shelters that accommodate pets. This grant aims to empower shelters to break the cycle of domestic violence by allowing women to keep their beloved pets during difficult times. By supporting organizations that facilitate this, the AKC Humane Fund fosters a community where both women and animals can find safety and solace together.

The American Legion Child Welfare Foundation (CWF) offers grants to nonprofit organizations dedicated to enhancing the welfare of children across the United States. Established in 1954, CWF prioritizes projects that address the physical, mental, emotional, and spiritual needs of youth. Grants are available annually from May 1st to July 15th, supporting initiatives that demonstrate a broad geographical impact. This foundation seeks to make a meaningful difference in the lives of children facing various challenges.

The Chevron Changing the Face of Golf Scholarship, awarded by the LPGA Foundation, aims to empower female high school seniors from minority backgrounds pursuing STEM studies. Established in 2022, this scholarship promotes diversity in golf and education, honoring Dinah Shore's legacy. By supporting young women, the LPGA Foundation continues its mission to change the face of golf and provide educational opportunities, enhancing representation in both golf and STEM fields.

The UNCF General Scholarship, offered by the United Negro College Fund, provides essential financial support to students enrolled full-time at one of 37 UNCF Member Institutions for the 2024-2025 academic year. This scholarship aims to enhance access to higher education for minority students, helping them thrive and graduate. The application process is designed to create a pool of eligible candidates for various scholarship opportunities, emphasizing the importance of education and community engagement.

The Wm. Wrigley's Foundation Scholarship, offered by the United Negro College Fund, supports undergraduate students enrolled in UNCF member schools for the 2025-2026 academic year. This scholarship provides up to $5,000 based on verified financial need. Eligible candidates must be majoring in specific fields such as engineering, business, or computer science, and maintain a minimum GPA of 2.5. This initiative reinforces the commitment to enhancing minority education and fostering future leaders.

The Craig H. Neilsen Foundation's Creating Opportunity & Independence Grant supports programs and research that enhance the quality of life for individuals with spinal cord injuries (SCI). It welcomes applications from nonprofit organizations and rehabilitation facilities in the U.S. and Canada, focusing on projects that foster independence, community participation, and capacity-building. Priority is given to initiatives that demonstrate broad impact and involve individuals with SCI, ensuring their needs and perspectives shape the proposed activities.

The NLN Steve Cerame Nurse Educator Scholarship Award supports aspiring nurse educators by providing up to $8,000 annually for master's or doctoral students. This award honors the legacy of NLN's former CFO and aims to facilitate the education of future nursing faculty. Eligible candidates must be NLN members and have completed at least one year of their program. The scholarship focuses on enhancing the nursing workforce and advancing educational excellence in nursing.

The Dr. Anita L. Pinc Memorial Scholarship, administered by the Quad Cities Community Foundation, provides financial assistance up to $1,000 to female students pursuing a medical degree in the U.S. Applicants must be enrolled in a medical school and have ties to Scott County, Iowa, or Rock Island County, Illinois. This renewable scholarship supports students committed to practicing medicine in the Quad Cities region, helping to foster local healthcare professionals.

The Researcher Connection Program by Uplifting Athletes Inc. supports travel expenses for rare disease researchers and doctoral students, fostering connections within the rare disease community. It emphasizes health equity by reserving at least 20% of funding for underrepresented researchers. Qualified applicants can receive up to $1,450 for travel costs related to attending relevant conferences and events, enhancing collaboration and awareness in the rare disease field.

York County Community Foundation

York County Community Foundation was founded in 1961 by generous visionaries who saw an opportunity to perpetually support their community by pooling charitable giving, investing it to grow over time and make grants to charity from the earnings on the pooled fund. It wasn’t until 1991 that the Community Foundation made a real push to build its assets so that it could become the kind of leading organization it is today. Donors are the crux of our existence; they are the reason we have been so successful over the years. Today, thanks to encouragement from many community leaders, we have enhanced our mission to include being a community leader and changemaker by working with community stakeholders to leverage our grantmaking and expertise for powerful community improvement.

Field of Study Scholarships

Through the Community Foundation, our donors have established scholarship funds focused on a specific field of study. Each scholarship expresses our donors' deep commitment to helping York County students achieve their educational goals.

Tom Adams, Jo Hunger, George Lamotte Scholarship Fund

This scholarship was created for York County students studying to become a dentist, a dental specialist, or a dental hygienist.

The NLN Nursing Education Scholarship Award offers up to $8,000 annually to support nurse educators pursuing advanced degrees. As the first organization dedicated to this cause, the NLN Foundation for Nursing Education aims to strengthen the nursing workforce in the U.S. and globally. Eligible candidates are NLN members and must be enrolled in accredited master's or doctoral programs, having completed at least one year of study. This initiative is vital for advancing nursing education and improving healthcare outcomes.