Best Grants for New Nonprofits in North Carolina

The Pets in the Classroom Grant Program provides financial support to educators in the US and Canada, enabling them to incorporate small animals into their classrooms. This initiative aims to enhance students' educational and personal development through direct interaction with pets. The program, established by the Pet Care Trust, invites applications from teachers, librarians, and other school staff who support student learning, fostering a nurturing environment for young learners.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Choose How You Respond Fund (in memory of Dr. Bryan Douglas) 

The purpose of the Choose How You Respond Fund is to provide funds to qualified individuals to cover expenses related to the treatment of cancer.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Reese Naylor Joy Fund

The purpose of the Reese Naylor Joy Fund is to provide funds to qualified individuals with a chronic or terminal illness to cover expenses of an event or experience that will bring joy and happiness to the child and their family. Grant requests will be considered for children up to the age of 21.

The Bright Ideas Education Grants program, supported by North Carolina’s Electric Cooperatives, empowers K-12 teachers to implement innovative projects in classrooms. With applications open from April to September, educators can seek funding for creative learning initiatives. Annually, around 600 grants are awarded, enhancing educational experiences across diverse disciplines. This initiative not only enriches classroom instruction but also strengthens community ties, demonstrating the cooperatives' commitment to improving quality of life for local students.

The U.S. Embassy Tokyo is launching a competition to promote study abroad opportunities in U.S. graduate schools. This initiative invites American and Japanese non-profit organizations to propose innovative programs aimed at increasing the enrollment of Japanese students in various graduate fields across the United States. The goal is to foster educational exchange and strengthen U.S.-Japan relations through enhanced academic collaboration.

The Lemelson Foundation Grant supports initiatives in invention education and entrepreneurship, aiming to empower young inventors and foster innovation. With over $300 million provided since its inception, the Foundation focuses on strengthening ecosystems for invention in the U.S. and developing countries. Organizations interested in aligning with their mission are encouraged to take an eligibility quiz and submit inquiries through their contact form. This commitment is crucial for driving impactful solutions to global challenges.

Arnold and Mabel Beckman Foundation

The Foundation was established in September 1977 by Dr. Arnold O. and Mrs. Mabel Beckman to give back to the scientific community.

“The mission of the Foundation is to support leading edge research, in the fields of chemistry and life sciences, broadly interpreted, and particularly to foster the invention of methods, instruments, and materials that open up new avenues of research and application in these sciences and related disciplines. My preference is to favor young investigators, new ideas, and a variety of projects rather than fund large, established ones of long duration.”

Current Foundation Initiatives

Today, the Foundation continues according to the vision laid out by Dr. and Mrs. Beckman:

• Supporting Young Scientists: through our annual grant programs, focused on the most promising young scientists
• Community Support activities: that promote science education and excellence in our local community
• Streamlined operations: so that we don't "spend money to give money away"

"Beckman Family" Awardee Community Support Grants

The Arnold and Mabel Beckman Foundation’s "Beckman Family" Awardee Community Support Grants are open to all current and former Foundation grant awardees and Executive Committee members, specifically from the Beckman Scholars Program, Arnold O. Beckman Postdoctoral Fellowship, Beckman Young Investigator, and Instrument Grants programs.

As a current or former Beckman awardee or Executive Committee member, if you are actively engaged as a volunteer or Board member in a youth STEM or STEAM organization in your local area, you may apply to this program for funding for a particular project with that organization.

Funding Priorities

Projects should be aligned with the Foundation’s aim of “supporting young scientists today for tomorrow’s breakthrough discoveries” and oriented toward achieving positive outcomes in at least one of the Foundation’s current funding priorities:

• Engaging youth in hands-on science and math activities to encourage curiosity and student-driven exploration and learning.
• Using technology to engage youth in STEM/STEAM.
• Promoting the Beckmans’ legacy of technology innovation and leadership amongst youth.

In addition, the following considerations should be addressed in a proposal for funding:

• Where possible, the Foundation’s contribution to a project or activity should help to build capacity within the nonprofit organization to continue the activity beyond the one-time grant.
• The Awardee/Executive Committee member should discuss how the program will increase access to STEM/STEAM opportunities for the target audience.
• The costs associated with the request should relate to a stand-alone STEM/STEAM project, event, or activity and not part of a broader program, event, or target audience outside the Awardee’s or Executive Committee member's local area.
• Youth registration to participate in the STEM/STEAM project, event, or activity should be open to all in the local area, when possible.

Process & Timeline

Grant funds are directly issued to the organization by the Foundation and include for acknowledgement an indication that the gift was made because their volunteer or Board member is a Beckman Awardee or Executive Committee member.

Requests must be submitted by the Beckman Awardee on behalf of a U.S. nonprofit 501(c)(3), or equivalent, organization exclusively serving youth in their local community. As a matter of policy, the Foundation does not provide grants to non-U.S. organizations or institutions. This program defines the terms “youth” and “youths” as individual(s) 17 years of age or younger.

The Kids to Parks Day School Grants Program offers funding up to $1,000 for Title I schools in the U.S. to enhance student engagement with parks and public lands. This initiative encourages hands-on learning experiences through outdoor activities and stewardship projects, promoting environmental education and healthy lifestyles. Eligible classrooms can apply, emphasizing student involvement in the application process. The program aims to empower students and teachers to foster a deeper connection with nature and their communities.

The Carol Ann and Ralph V. Haile Jr. Scholarship Program, established by the Carol Ann and Ralph V. Haile Jr. Foundation in partnership with UNCF, supports students attending UNCF member institutions, HBCUs, or other accredited four-year colleges. This renewable merit-based scholarship aims to enhance educational opportunities for residents of specific counties in Kentucky, Ohio, and Indiana, particularly focusing on those majoring in education or STEM fields.

Radio Flyer is dedicated to supporting organizations that promote outdoor play and well-being for children. They focus on charitable giving to national organizations like The Starlight Children’s Foundation, which aids children’s health, and partner with KaBOOM! to build playgrounds for underprivileged kids. Local nonprofits in the Chicagoland area are also supported, emphasizing education and health for children up to eight years old. This mission aligns with their goal of creating smiles and lasting memories through play.

The NIOSH K01 grant offers vital support for early-career researchers in occupational health, providing 'protected time' for mentorship and professional development. This funding aims to bridge the gap from postdoctoral training to independent research, fostering the next generation of investigators. By emphasizing skill enhancement and independence, the program plays a crucial role in advancing safety and health research. Applicants must articulate their mentorship needs and demonstrate the potential for increased autonomy in their research careers.

Orange County Economic Development Department 

The Economic Development Department serves to diversify Orange County’s local economy by promoting the growth, retention and recruitment of small and locally-owned businesses, local agricultural and food processing ventures, entrepreneurial innovation start-ups, and large business employers engaged in a variety of retail trades, hospitality centers such as hotels and restaurants, light industrial manufacturing, logistics distribution centers, research and commercial office development. The Department strives to identify specific business prospects in these strategic sectors which are determined to be desirable, growth-oriented, environmentally clean, that pay at or above the Orange County living wage, and offer health care and related employment benefits. The underlying goal is to achieve a net increase in retail and property tax revenues to the County, and employment opportunities for our residents.

Agricultural Economic Development Grant Program

Purpose

This program is intended to provide assistance to Orange County farmers in developing new sources of agricultural income through the provision of grants. Farmer applicants must be able to demonstrate that their existing operation is a verifiable farm business meeting the following requirements:

• Land - owned or leased by applicant in Orange County
• Infrastructure - suitable for existing operation and any required expansion
• Market - defined, accessible, with history of sales
• Experience - knowledge, ability, and demonstrated relevant experience
• Concept – demonstrates a valid need and specific request

Grants for Research About Urban Communication Issues

Since our launch in 2005, the Urban Communication Foundation has provided awards and grants to dozens of distinguished scholars, researchers, and journalists to recognize and support provocative work that contributes in significant ways to the discourse around urban communication issues.

While most of our recipients hail from academia and journalism, we also encourage submissions from other practitioners whose work will lend new insights into the discipline, raise broader awareness of related socio-political, economic, and cultural concerns, or influence public policy.

Gene Burd Grant for Research in Urban Journalism Studies

The Association for Education in Journalism and Mass Communication has partnered with the Urban Communication Foundation to create the Gene Burd Grant for Research in Urban Journalism Studies. The purpose of this annual grant is to stimulate research that explains, enlightens, inspires, and improves the practice and study of journalism and communication in order to advance our understanding of journalism in urban environments.

About the Foundation

Our Mission

Beyond Batten Disease Foundation was established to eradicate juvenile Batten disease by raising awareness and funds to accelerate research for a treatment or cure.

About Funding

BBDF is dedicated to collaboratively developing, funding, and managing fundamental, preclinical, IND-enabling, translational and clinical research to improve the lives of children and young adults with CLN3 disease. Since 2008, BBDF has been the largest funder of juvenile Batten (CLN3) disease research, ranging from basic discovery research to translation into therapies. To inform our research initiatives, BBDF gathers information from one-on-one meetings, broad group discussions, scientific peer-reviewed publications, conference proceedings, drug pipelines, and tailored merit reviews into the foundation’s decision-making processes. Input comes from across the Research and Development spectrum including academia, biotechnology, the pharmaceutical sector, and clinicians, caregivers, and patients.

Our research funding decisions are based on these research objectives:

1) Supporting basic research to discover new mechanisms of disease, targets, and treatments

2) Supporting projects which facilitate execution of clinical trials such as expanding patient registries

3) Identifying biomarkers and other innovative clinical endpoints

4) Supporting projects that de-risks pharmaceutical investments in Batten disease

Foundation-Directed Research

The largest portion of the foundation’s portfolio is directed research. The foundation fills gaps in juvenile Batten disease research by funding high-impact projects and breakthrough technologies that will lead to disease mitigation and cure.

BBDF’s Principal Scientist regularly interacts with leaders in research and development across the entire therapeutic pipeline for Batten, as well as for adult forms of neurodegeneration (e.g., Alzheimer’s and Parkinson’s disease), and other related rare genetic diseases. To supplement this dialogue, BBDF creates specialty boards and steering committees to lead the development of its projects. A specialty board typically comprises ~200 years of combined experience specific to the proposed activity.

Investor-Initiated Research (Applying for a research grant)

In addition to directed research, BBDF accepts and awards research proposals. Because great ideas do not follow a schedule, we do this on a rolling submission basis. All budgets are carefully reviewed along with the proposed body of work. Applicants may be asked to revise their budgets and/or allow BBDF to share a summary of the proposal with other funders for the purpose of gathering additional support. Sometimes, the foundation will offer the applicant additional funding to incorporate additional expertise or methods into his or her plan.

Sports Matter Mission

We believe that sports change lives. In addition to physical and mental health benefits, sports have the power to change our perspectives, our character and our communities for the better. This core belief has guided DICK’S Sporting Goods and The DICK’S Sporting Goods Foundation since the beginning – but not everyone has the same access to play. Through grants and other support, The DICK’S Foundation Sports Matter Program helps under-resourced 501c3 organizations, schools and community teams across all 50 states provide opportunities for youth to play sports.

Why It Counts

• Low-Income Kids Play at Half the Rate of Wealthier Peers
• Participation in Team Sports has Declined 4% Since 2017
• One in Three Kids Can't Participate in the Sports They Want 
• Number of Kids Playing Multiple Sports Has Declined

Sports Matter Program

We Believe Every Kid Deserves a Chance to Play

The Sports Matter Program focuses on supporting youth sports in under-resourced communities.

All grant applications are made subject to review of the applying organization’s reputation and activities, and its agreement to comply with applicable terms and conditions. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Fund

Help with healthcare costs for mucopolysaccharidosis type VII

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Mucopolysaccharidosis Type VII (MPS VII) Health Equity Fund

Help with healthcare costs for mucopolysaccharidosis type VII (health equity)

This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

The Women's Fund of North Carolina, a program of the North Carolina Community Foundation, aims to enhance the lives of women and girls across the state through grants ranging from $2,500 to $5,000. This fund prioritizes organizations that address diverse needs and challenges faced by women, especially those led by marginalized populations. Grant decisions are made by a committee, and applicants are notified within 90 days after the application deadline.

The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.

The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.

The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.

The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.

The Rural Health Network Development Planning Program aims to enhance rural health care by fostering integrated health care networks. It focuses on collaboration among entities to bolster local capacity and improve care coordination in underserved areas. By achieving efficiencies and expanding access to essential services, the program seeks to strengthen the overall rural health system while promoting the use of health information technology and exploring innovative care delivery models.

The Rural Health Network Development Program aims to enhance health care access in rural areas by supporting integrated health care networks. It offers two funding tracts: the Network Advancement Tract for established networks to overcome operational barriers and the Network Development Tract for early-stage networks to plan and expand services. Both tracts focus on improving care coordination, health outcomes, and operational efficiency, thereby strengthening the rural health care system.

The Japan America Society / Japan Society Capacity Building Grant Program supports grassroots initiatives aimed at enhancing mutual understanding between the U.S. and Japan. With grant amounts up to $30,000 for 12 months, eligible organizations can apply for projects in fundraising, strategic planning, public relations, and more. The program prioritizes projects that foster collaboration and demonstrate sustainability, ensuring a lasting positive impact on communities.

The Grant for U.S.-Japan Community Grassroots Exchange Program aims to foster cultural exchange between the U.S. and Japan by funding grassroots programming initiatives. Eligible projects must include at least ten events within a 12-month period, focusing on various Japan-related topics. The grant, offering up to $30,000, prioritizes innovative outreach and sustainability. Applications are welcome from U.S. universities and nonprofit organizations that promote cultural exchange, ensuring diverse audiences are engaged.

The JFNY Grant for Japanese Studies provides funding of up to $5,000 for U.S.-based institutions with 501(c)(3) status to enhance understanding of Japan through academic projects. Eligible projects include conferences, lectures, and symposia, whether in-person or virtual. The grant covers expenses such as honoraria, travel, accommodation, and research materials. Applications are accepted on a rolling basis, and submission is required at least three months prior to the project start date.