Science Education Grants for Nonprofits from Amgen Foundation
Nonprofit 501(c)(3) organizations and eligible public institutions in North Carolina can seek Amgen Foundation support for science education programs and community-strengthening initiatives. The foundation prioritizes teacher professional development and hands-on, technology-enhanced science learning, and may also back civic engagement efforts that align with its mission in communities where Amgen operates.
The Amgen Foundation Inc
Creag Foundation Support for Innovative Nonprofits
Nonprofit 501(c)(3) organizations with at least one year of status and innovative approaches to human services and social problems may be eligible for funding, including those in North Carolina. Grants from Creag Foundation help nonprofits explore new ways to address societal issues, which could indirectly strengthen staff skills and organizational capacity.
Creag Foundation
North Carolina Youth Programs Funding via Dan Paul Foundation
Nonprofit 501(c)(3) organizations supporting youth health, education, and development in North Carolina can seek up to US $15,000 for direct-service programs and related training needs. The Dan Paul Foundation supports work such as early childhood development, child advocacy, homelessness and poverty services, refugee enrichment, and environmental responsibility education, which may include professional development for staff and caregivers.
The Dan Paul Foundation
Draper Richards Kaplan Grants for North Carolina Innovators
With a mission to dramatically improve lives, Draper Richards Kaplan Foundation provides North Carolina early-stage social impact organizations with up to US $300,000 over three years in unrestricted funding or investment capital plus intensive capacity-building support. Eligible independent nonprofits and impact-first for-profits must serve underserved communities and offer scalable, systems-focused solutions.
Draper Richards Kaplan Foundation
North Carolina Tech-Enabled Programs Funding via Cisco
Nonprofit and NGO programs using technology for crisis response, education access, or economic empowerment in North Carolina can access funding through Cisco Systems Foundation, with awards up to US $100,000. Eligible organizations must primarily serve economically underserved communities and keep overhead below 25 percent; applications are accepted year-round starting with a brief LOI.
Cisco Systems Foundation
William Randolph Hearst Foundation Arts Grants in North Carolina
Nonprofit cultural institutions in North Carolina offering arts or science programming for large U.S. audiences can seek more than US $100,000 to support impactful programs, capital needs, or limited general support. William Randolph Hearst Foundation prioritizes arts education, artist development, and STEAM-focused science initiatives that demonstrate measurable, lasting benefits and organizational sustainability.
William Randolph Hearst Foundation
South Arts Grants for North Carolina Arts
Focused on professional development, South Arts invites North Carolina arts nonprofits and public or tribal arts agencies with budgets under $500,000 to build organizational capacity. Eligible Southern arts organizations can receive up to US $1,000 for staff and board training, conferences, workshops, travel, and consultant fees that strengthen long-term sustainability.
South Arts, Inc.
Community and Education Funding for Charities from La Roche
North Carolina accredited charities running humanitarian, education, community, environmental, or arts projects can access funding through La Roche’s global philanthropy program. Support focuses on innovative, sustainable initiatives that may engage Roche expertise or employees and are managed locally through Roche affiliate offices in the same country where the project operates.
La Roche, Inc.
Humanitarian and Health Funding for Nonprofits from Semnani Family Foundation
Semnani Family Foundation provides North Carolina nonprofits and other organizations focused on health, education, and humanitarian aid with support for programs serving marginalized and vulnerable communities. U.S.-based groups working on healthcare access, disaster relief, child welfare, or related human and social services may be eligible alongside organizations in other countries.
Semnani Family Foundation
Life Sciences Tech Funding for Universities from North Carolina Biotechnology Center
Applications due Aug 5, 2026
Researchers at North Carolina universities and nonprofit research institutes can apply for North Carolina Biotechnology Center’s Translational Research Grant, with awards up to US $144,000 to advance life sciences technologies toward commercialization. Funding supports product-focused translational research, de-risking inventions, and building partnerships that may strengthen professional development for academic project teams.
North Carolina Biotechnology Center
Alliance for Full Acceptance Support for LGBTQ+ Youth
Applications due Sep 1, 2026
North Carolina nonprofits supporting LGBTQ+ youth programs can access funding through Alliance for Full Acceptance for programming, organizational development, and youth-focused initiatives. Grants of US $500 - US $4,000 also serve eligible organizations in South Carolina and Georgia, including GSAs, campus resource centers, and collaborative projects that advance social justice and emotional health for LGBTQ+ youth.
Alliance for Full Acceptance
Mary Duke Biddle Foundation Arts Grants in North Carolina
Letter of inquiry due Sep 5, 2026
Arts-focused 501(c)(3) nonprofits and fiscally sponsored groups in North Carolina can receive US $5,000 - US $10,000 in one-year general operating support to strengthen cultural organizations and emerging arts initiatives. The Mary Duke Biddle Foundation funds organizations centered on arts, arts education, or student academic success in Chatham, Durham, Orange, or Wake counties, including those building staff and organizational capacity.
Mary Duke Biddle Foundation
Community Foundation of Burke County Support for Facility Costs
Applications due Oct 1, 2026
Tax-exempt 501(c)(3) organizations in North Carolina that serve Burke County residents and need help with facility costs can apply for this grant. Focused on facility expenses that support or expand charitable, religious, humanitarian, or educational programs, the Community Foundation of Burke County prioritizes both planned and emergency facility needs, which may include staff training or space for professional development activities.
Community Foundation of Burke County
Dudley T Dougherty Foundation Grants for North Carolina Community Services
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations seeking support for community services, environmental conservation, or peacebuilding projects in North Carolina may be eligible for this funding. With a mission to support positive change, Dudley T Dougherty Foundation provides charitable organizations with grants that could include staff training or professional development within broader program needs.
Dudley T Dougherty Foundation Inc
Youth and Family Services Funding from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations near TJX locations in North Carolina can apply for TJX Foundation grants to support basic needs, youth enrichment, workforce readiness, and domestic violence safety programs. Eligible groups must align with TJX’s community mission, be within 15 miles of a store, distribution center, or office, and meet specific nondiscrimination and prior-funding requirements.
The Tjx Foundation Inc
Lawrence Foundation Support for North Carolina Programs
Applications due Nov 1, 2026
North Carolina 501(c)(3) public charities, public schools, and libraries can seek unrestricted funding for environmental, human services, disaster relief, or other community programs. Focused on broad charitable impact, the Lawrence Foundation offers US $5,000 - US $10,000 program or operating grants, which may help cover staff training or professional development within eligible projects.
Lawrence Foundation
Max and Victoria Dreyfus Support for Community Programs
Applications due Nov 11, 2026
Nonprofit organizations in North Carolina seeking support for community programs, education, arts, health facilities, or environmental and wildlife activities can apply for grants ranging from US $1,000 - US $20,000. Grants from Max and Victoria Dreyfus Foundation help U.S. nonprofits where relatively small awards can make a significant difference, including professional development-related efforts.
Max and Victoria Dreyfus Foundation
Literary Project Funding for Southern Writers via South Arts
Applications due Dec 4, 2026
Individual writers and literary arts nonprofits in North Carolina and the broader South Arts region can apply for South Arts’ Literary Arts Grants, awarding up to US $5,000 for creative projects and career growth. Funding supports new or in-progress literary work, community engagement activities, and professional development such as conferences, workshops, retreats, or residencies.
South Arts, Inc.
Duke Endowment Child Welfare Grants in North Carolina
Pre proposal due Dec 15, 2026
Child- and family-serving nonprofits in North Carolina seeking to implement or sustain evidence-based programs to prevent or treat child abuse and neglect may be eligible for this funding. Grants from The Duke Endowment help agencies strengthen implementation support, develop innovative, data-driven models, and advance advocacy to improve child and family well-being systems.
The Duke Endowment
Dr Scholl Foundation Community Grants in North Carolina
Letter of inquiry due Jan 31, 2027
North Carolina 501(c)(3) nonprofits seeking project funding in education, social services, health care, civic and cultural, or environmental programs can access funding through the Dr Scholl Foundation, with typical awards of US $5,000 - US $25,000. Organizations may request one year of support and one application per grant cycle, primarily for U.S.-based work.
Dr Scholl Foundation
Mary Duke Biddle Foundation Arts Grants in North Carolina
Letter of inquiry due Feb 15, 2027
Arts-focused 501(c)(3) organizations and fiscally sponsored groups in North Carolina’s Chatham, Durham, Orange, and Wake counties can seek multi-year general operating support to strengthen or expand their arts programming. Focused on arts and organizational development, the Mary Duke Biddle Foundation offers US $20,000 - US $50,000 annually to developing and established organizations, including those investing in staff and leadership capacity.
Mary Duke Biddle Foundation
Community Development Fellowships for Nonprofits from NCRC
Applications due Feb 28, 2027
Nonprofit and community development organizations working on housing, small business, or workforce development can host an NCRC graduate fellow to advance real-world projects. National Community Reinvestment Coalition provides North Carolina and other U.S. NCRC member organizations with professional development support through mentored, in-person fellowships that bring fresh talent and help build the next generation of community development leaders.
National Community Reinvestment Coalition Inc
Community Foundation Support for North Carolina Youth
Applications due Mar 6, 2027
North Carolina 501(c)(3) organizations improving the lives of children and families can receive up to US $1,000 for youth-focused programs through the Burke Youth Organized Philanthropists Grant. Community Foundation of Burke County provides funding for projects in Burke County that support children’s mental health, family well-being, and access to the arts for ages 0–18.
Community Foundation of Burke County
O'Reilly Automotive Foundation Workforce Grants in North Carolina
Applications due Apr 15, 2027
Nonprofit 501(c)(3) organizations in North Carolina focused on workforce readiness, literacy, economic stability, or related community services can seek project, operating, or capital support. With a mission to improve quality of life for underserved people, O'Reilly Automotive Foundation provides funding in communities where O’Reilly Auto Parts has a business presence.
O'Reilly Automotive Foundation Inc
South Arts Support for North Carolina Arts
Applications due Apr 22, 2027
Nonprofit and governmental arts presenting organizations in North Carolina can receive up to US $1,000 for staff and guest artist travel, registration, and related professional development costs. South Arts supports film, visual, performing, traditional, literary, and multidisciplinary arts presenters seeking new conferences, festivals, workshops, exhibitions, or virtual training opportunities that strengthen their programming and organizational capacity.
South Arts, Inc.
Approximately US $1,500,000
Child Care Training Funding for Nonprofits from NCDHHS
Applications due May 26, 2027
State agencies, universities, and 501(c)(3) nonprofits in North Carolina can apply for approximately US $1,500,000 to design and manage a statewide child care health consultation network, emphasizing technical assistance and professional development for early educators. North Carolina Department of Health and Human Services seeks one grantee with strong ECE systems expertise and experience in intensive coaching and culturally inclusive training.
North Carolina Department of Health and Human Services (NCDHHS)
National Trust Grants for North Carolina Battlefields
Applications due Jun 2, 2027
Public agencies and 501(c)(3) nonprofits in North Carolina can seek US $2,500 - US $10,000 to plan or expand efforts to preserve battlefields, viewsheds, and related historic structures. National Trust for Historic Preservation funding supports planning, professional expertise, capacity building, and innovative education and outreach that may strengthen staff skills and organizational effectiveness.
National Trust for Historic Preservation