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Best Unrestricted Grants for Nonprofits in North Carolina

Find the perfect Unrestricted grants for nonprofits in North Carolina on Instrumentl. 10,000+ Unrestricted grants for nonprofits in North Carolina in the United States.

10,000+

Available grants

$2.70B

Total funding

$5K

Median grant

10,000+ grants
$2.70B total
$5K median

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9,803 Results based on applied filters

The Steven Scott Quinn Scholarship Fund

Stark Community Foundation
Private
United States
More than US $500
The Steven Scott Quinn Scholarship Fund, established by the Stark Community Foundation, aims to support Stark County, Ohio residents pursuing higher education in fields such as culinary arts, hospitality, nursing, nutrition, physical therapy, and occupational therapy. This initiative reflects the Foundation's long-standing commitment to enhancing the community through philanthropy and addressing diverse educational needs since its inception in 1963.
Education - Higher Education Vocational & Trade Education Education - High School +5 more

COPIC Medical Foundation Grants

Copic Medical Foundation
Private
United States
Unspecified amount
The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.
Medical Education & Professional Training Health Information Technology Patient Safety +1 more

NAMM Foundation: Music Research Grants

Namm Foundation
Private
United States
US $5,000 - US $25,000
The NAMM Foundation Global Grantmaking Program provides music research grants aimed at enhancing music education and career mobility. With a focus on eliminating barriers for underrepresented communities, grants range from $5,000 to $25,000. The foundation supports high-impact organizations that demonstrate measurable outcomes and align with its mission of fostering music makers. Eligible applicants include those with a strong research track record and innovative project proposals that do not duplicate existing studies.
Music Workforce Preparation & Job Readiness Music Education +1 more

AHRQ Understanding and Improving Diagnostic Safety in Ambulatory Care: Incidence and Contributing Factors (R01) (349962)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The AHRQ is inviting proposals for research focused on improving diagnostic safety in ambulatory care settings. This funding opportunity aims to understand the incidence and contributing factors of diagnostic errors that occur across various ambulatory care services. Proposals should address the complexities of diagnostic safety to enhance patient care and outcomes.
Patient Care & Services Home Health Care Health Care Access & Delivery +1 more

Cohort Studies of HIV/AIDS and Substance Use (U01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.
HIV / AIDS Addiction & Substance Use Disorders

Nancy Talbot Postdoctoral Research Fellowship

The American Occupational Therapy Foundation Inc
Private
United States
US $30,000
The Nancy Talbot Postdoctoral Research Fellowship, established by the American Occupational Therapy Foundation, offers $30,000 for one year to support postdoctoral research in occupational therapy. This fellowship aims to enhance diversity in the field by funding individuals from underrepresented racial and ethnic groups, as identified by the NSF. Eligible candidates must hold an OT degree or relevant doctorate, have a mentor, and conduct research at a U.S. academic institution.
Physical Therapy Occupational Therapy Medical Education & Professional Training +4 more

Mobilize Power Fund Grant

Third Wave Fund
Private
American Samoa, Guam +4 more
Up to US $20,000
The Mobilize Power Fund Grant, offered by the Third Wave Fund, supports youth-led gender justice activism. This rapid response fund targets organizations led by young women of color and LGBTQ+ youth, providing up to $10,000 for urgent needs. It prioritizes groups addressing recent incidents that threaten their work, fostering community power and leadership. Organizations with budgets under $500,000 can apply, aiming for impactful, time-sensitive initiatives that promote social change.
Sexuality & LGBTQIA+ Rights Women's Rights & Equality Reproductive Rights +1 more

Dr. Carol J. Chrisman Nursing Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Dr. Carol J. Chrisman Nursing Scholarship, offered by the Ashland County Community Foundation, supports registered nurses and nursing students from Ashland County pursuing advanced degrees at Ashland University. This scholarship honors Dr. Chrisman's legacy in nursing and community health, encouraging local nurses to further their education. Eligible applicants include full-time nursing students and those employed in public health within the area, with prior recipients allowed to reapply once.
Education - Higher Education Career / College Preparation Education - High School +3 more

Chronic Lymphocytic Leukemia Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Chronic Lymphocytic Leukemia Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients battling chronic lymphocytic leukemia (CLL). This fund provides essential support for prescription copays and premiums, ensuring that patients can access necessary treatments without the stress of financial constraints. Since its inception, the foundation has awarded over $1.2 billion in grants, helping more than 1.1 million patients. The initiative emphasizes the importance of accessible healthcare and aims to improve the quality of life for those affected by this condition.
Cancer / Oncology Leukemia Health Care Access & Delivery +1 more

Congenital Sucrase-Isomaltase Deficiency Fund

Healthwell Foundation
Private
United States
Up to US $10,000
The Congenital Sucrase-Isomaltase Deficiency Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from this genetic disorder. By providing assistance with prescription drugs and treatment costs, the fund ensures that vital medications are accessible, allowing patients to manage their condition effectively. In 2024, the Foundation is expected to award over $1.2 billion in grants, showcasing its commitment to enhancing healthcare access for those in need.
Health Care Access & Delivery Endocrine & Metabolic Diseases Diabetes +1 more

Morgan Stanley Alliance for Children’s Mental Health Innovation Awards

Morgan Stanley Foundation Inc.
Corporate
United States
US $100,000
Morgan Stanley Alliance for Children’s Mental Health Innovation Awards aim to fund innovative mental healthcare solutions for children in the U.S. This initiative invites U.S.-based 501(c)(3) charities with revenues under $5 million to submit projects. With up to $550,000 in grants, the program focuses on addressing critical mental health issues among youth, fostering equity in access to care, and supporting nonprofits led by young leaders. Awards include up to $100,000 for general and $50,000 for Next Gen projects.
Depression / Anxiety Children’s Mental Health Social / Emotional Learning & Development

Investigator Sponsored Studies Program

Alkermes
Corporate
United States
Up to US $300,000

Alkermes

At Alkermes, we apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders, including addiction, serious mental illness and sleep disorders. With our portfolio of marketed medicines and investigational pipeline candidates, we seek to make a meaningful difference in the way people manage these chronic diseases. Our patient-inspired science, integrated research strategy, sophisticated development capabilities and specialized commercial infrastructure enable us to pursue the development and commercialization of innovative new medicines, including those for people with conditions that have traditionally been overlooked or stigmatized.

Our greatest strengths at Alkermes are our people and our inherent empathy for patients, families and caregivers. Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We work with urgency to develop new treatment options for people living with these conditions.

Investigator Sponsored Studies Program

Alkermes seeks to support research designed and conducted by independent clinicians and scientists through our Investigator Sponsored Studies (ISS) program. Alkermes may occasionally announce a Request for Proposals (RFP) for research in clinical areas where gaps in data have been identified. 

The ISS research Alkermes supports must be based in the United States and is typically conducted by experienced researchers who have an established history of successfully completing research with independent funding. Alkermes can provide its marketed products to the ISS programs it supports. In addition, there may be financial support available, but please note that study budgets cannot exceed $300,000 (inclusive of overhead).

  • ISS Areas of Interest
    • Sleep Disorders
    • Schizophrenia & Bipolar I Disorder
    • Schizophrenia
Patient Care & Services Sleep Schizophrenia +2 more

State Pilot Program for Treatment for Pregnant and Postpartum Women (363808)

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The State Pilot Program for Treatment for Pregnant and Postpartum Women aims to enhance the state's capacity to deliver integrated and evidence-based services for substance use disorders and maternal mental health. The initiative focuses on supporting pregnant and postpartum women and their families, ensuring they receive comprehensive care tailored to their unique needs. Funded by the Substance Abuse and Mental Health Services Administration, this program is a vital step toward improving health outcomes for vulnerable populations.
Mental Health & Psychiatric Diseases Family Services Addiction & Substance Use Disorders +2 more

Measurement and Evaluation Graduate Student Award

Society Of Health And Physical Educators
Private
United States
Unspecified amount
The Measurement and Evaluation Graduate Student Award, offered by SHAPE America, aims to support graduate students specializing in psychomotor measurement and evaluation. This scholarship assists with professional expenses, ensuring candidates can focus on their studies. Eligible applicants must be current SHAPE America members and pursuing relevant master's or doctoral degrees. The award prioritizes those who have completed their first year of study, promoting excellence in health and physical education across the U.S.
Kinesiology & Sports Medicine Education - K through 12 Dance +3 more

NBA Foundation Grants

National Basketball Association Foundation
Private
Canada, United States
More than US $25,000
The NBA Foundation Grants aim to empower Black youth by providing economic opportunities through skills training, mentorship, and career advancement programs. Established by all 30 NBA teams, the foundation focuses on organizations aligned with its mission, specifically those serving Black youth in NBA markets. Applications for 2024 grants are now open, with a review process taking 12-14 weeks. This initiative is crucial for promoting sustainable economic and racial justice in communities.
Career / College Preparation Black American Services Youth Services +2 more

Juliette Low’s Amazing Girls Scholarship

East Texas Communities Foundation
Private
United States
US $1,000
The Juliette Low’s Amazing Girls Scholarship, established in 2011 by the East Texas Communities Foundation, is aimed at female graduating seniors from Smith County who have been active in Girl Scouts. This scholarship supports educational pursuits for students attending any college in the U.S. Applicants must demonstrate financial need and have a minimum GPA of 3.00. The award amount is $1,000, and preference is given to recipients of the Girl Scout Gold Award. Reapplication is encouraged.
Academic Scholarship Programs Educational Access & Equity Education - Higher Education +3 more

NASPGHAN Foundation Abbott Advanced Fellowship Training in Pediatric Nutrition

North American Society For Pediatric Gastroenterology, Hepatology & Nutrition
Association/Society
United States
US $70,000
The NASPGHAN Foundation Abbott Advanced Fellowship in Pediatric Nutrition offers up to $75,000 for one year of advanced training in pediatric nutrition for members of NASPGHAN. This fellowship aims to enhance pediatric nutrition expertise by supporting a well-defined clinical experience and focused research project. Eligible applicants must be MDs or DOs and members in good standing, with a preference for those seeking training at different institutions. This initiative addresses the increasing importance of pediatric nutrition in child health.
Eating Disorders Digestive System Health & Diseases Nutrition & Healthy Eating +1 more

Partners in Arts Scholarship

East Texas Communities Foundation
Private
United States
US $1,000
The Partners in Arts Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors from Smith County who have engaged in performing or visual arts and plan to pursue a related major in college. This scholarship highlights the importance of arts education and aims to empower students to achieve their academic goals. Eligible applicants must demonstrate a commitment to the arts and meet specific criteria, ensuring that funding is awarded to deserving candidates.
Art Education Music Education Education - Higher Education +4 more

Mexican Scholarship

Central Indiana Community Foundation
Private
United States
Unspecified amount
The Mexican Scholarship, established by the former Consulate of Mexico in Indianapolis, aims to support students of Mexican descent in pursuing higher education. Funded by the Central Indiana Community Foundation, this scholarship is open to Indiana residents enrolled in accredited colleges or vocational schools. Applicants must demonstrate financial need, maintain a GPA of 3.0 or higher, and preference is given to those of Mexican heritage. Award funds can be utilized for tuition, fees, and essential educational expenses.
Education - Higher Education Education - High School Academic Scholarship Programs +3 more

SEFSC Bluefin Tuna Research Program

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
US $25,000 - US $300,000
The SEFSC Bluefin Tuna Research Program aims to enhance science-based fisheries management for Atlantic bluefin tuna by improving knowledge of their fisheries, biology, and population dynamics. This initiative encourages collaborations with ICCAT and its partners to support multi-year research efforts focused on the movement and mixing of eastern and western Atlantic bluefin populations, ultimately contributing to better management practices for sustainable fisheries.
Marine Biology Ichthyology (Fish) Fisheries

Community Charter Network Scholarship

Central Indiana Community Foundation
Private
United States
Unspecified amount
The Community Charter Network Scholarship, provided by the Central Indiana Community Foundation, assists students from Fall Creek Academy or University Heights Preparatory Academy in covering post-secondary educational expenses. This scholarship aims to support those who demonstrate financial need and excel academically. Eligible applicants include former students of these institutions or residents within the IPS district. Awards vary based on available funds and may cover tuition, fees, and other educational costs.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +3 more

Imagine Learning Foundation: Signature Grant Program

Imagine Learning Foundation
Private
United States
US $25,000 - US $100,000
The Imagine Learning Foundation's Signature Grant Program aims to enhance the well-being of learners by supporting social and emotional learning (SEL) initiatives. By bridging classroom and community efforts, it fosters healthier environments for youth, families, and educators. The program prioritizes funding for organizations addressing critical issues like chronic absenteeism and housing insecurity. In 2024, the foundation will allocate over $400,000 to impactful projects, furthering its mission to cultivate supportive learning experiences both in and out of the classroom.
Youth Services Family Services Teacher Development & Training +4 more

Truist Foundation: Inspire Awards

Truist Foundation Inc
Private
United States
US $10,000 - US $250,000

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

  • Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
  • AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
  • Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
  • Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

  • First place: $250,000
  • Second place: $150,000
  • Runners-up: $25,000
  • Audience favorite: $75,000

Business Development Financial Literacy Entrepreneurship +4 more

Nationwide Insurance Foundation Grant

Nationwide Insurance Foundation
Corporate
Alachua County, Florida, Bexar County, Texas +12 more
Unspecified amount
The Nationwide Insurance Foundation Grant aims to enhance community quality of life by providing support to nonprofits in areas where many Nationwide members reside. Since 2000, the foundation has donated over $700 million to various organizations, focusing on food security, crisis stabilization, economic empowerment, and children's wellbeing. Grants are available for general operating support, project/program support, and capital support, with a commitment to matching associate contributions.
Crisis Intervention Disaster Relief / Humanitarian Aid Basic Human Needs +3 more

HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $140,000
The HEAL Initiative's Career Development Awards aim to empower early career researchers and clinicians in implementation science. By providing training and funding, this initiative seeks to address substance use prevention and treatment through research projects that align with the HHS Overdose Prevention Strategy. Focused on vital areas such as opioid prescribing, OUD treatment, and recovery support, the program aspires to cultivate a new generation of experts who will significantly impact addiction clinical practices and mentorship.
Drug Use Disorder Addiction & Substance Use Disorders

Rural Maternity and Obstetrics Management Strategies Program (363582)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.
Reproductive Health Women's Health Maternal And Perinatal Health +1 more

Brave Beginnings Grants

Will Rogers Motion Picture
Private
United States
Unspecified amount
Brave Beginnings Grants, under the Will Rogers Motion Picture Pioneers Foundation, focus on enhancing neonatal care by providing vital equipment to hospitals. Since 2006, the program has awarded approximately $1 million annually to Neonatal Intensive Care Units (NICUs) across the U.S. Following a suspension due to COVID-19, the 2026 grant cycle is now open, with applications due by February 13, 2026. This initiative aims to ensure the availability of lifesaving equipment for newborns in critical need.
Obstetrics & Neonatal Care Children’s Health & Pediatrics

Unrestricted Grants for Nonprofits in North Carolina Highlights

Looking for unrestricted grants for nonprofits in North Carolina?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in North Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in North Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Unrestricted grants for nonprofits in North Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

70 Unrestricted grants for nonprofits in North Carolina over $25K in average grant size

51 Unrestricted grants for nonprofits in North Carolina over $50K in average grant size

35 Unrestricted grants for nonprofits in North Carolina supporting general operating expenses

200+ Unrestricted grants for nonprofits in North Carolina supporting programs / projects

1,000+ Grants on Instrumentl focused on Environment

2,000+ Grants on Instrumentl focused on Community Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in North Carolina?

Most grants are due in the first quarter.

Q1
30.4%
Q2
22.4%
Q3
26.2%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in North Carolina?

Grants are most commonly $17,500.

$500 $500 Min.
$17,500 $17.5 K Median
$477,452 $477.5 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for North Carolina?

Grants are most commonly $131,121.

$131,121

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in North Carolina year over year?

In 2024, funders in North Carolina awarded a total of 70,602 grants.

2022 63,850

2023 62,335

2024 70,602

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in North Carolina given out in North Carolina, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in North Carolina changing over time?

Funding has increased by 15.49%.

2022 $7,927,620,616

2023 $7,987,830,464
0.76%

2024 $9,224,796,270
15.49%

North Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Durham County, Orange County, and Mecklenburg County receive the most funding.

County Total Grant Funding in 2024
Durham County $2,942,551,198
Orange County $2,549,339,233
Mecklenburg County $1,468,677,341
Wake County $1,122,908,782
Buncombe County $444,853,701

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