Best Small Grants for Nonprofits in Ohio

The National Cancer Institute (NCI) seeks to enhance the validation of biomarkers and assays for cancer detection and treatment through its UH3 funding mechanism. This initiative supports multi-disciplinary collaborations to validate existing assays over three years using clinical trial specimens. Emphasis is placed on harmonizing laboratory tests and validating pharmacodynamic markers. Projects should not focus on early-stage technology development but aim for integration into clinical studies as investigational assays.

The Washington Tree Fruit Research Commission is inviting research proposals aimed at apple crop protection, emphasizing organic practices and pollinator protection. Key areas of focus include the management of pests like Codling Moth and Fire Blight, testing new crop protection products, enhancing soil health, and developing efficient monitoring techniques. Collaboration among institutions is encouraged, and projects should aim for practical industry applications to ensure sustainable and profitable tree fruit production.

The HIP Graduate Student Award supports first to third-year graduate students in the U.S., Canada, and Mexico aiming for a career in academic hematology. Offering a $40,000 annual stipend for two years, it funds tuition, research, and travel to the ASH annual meeting. Eligible candidates must conduct blood sciences research and demonstrate commitment to the field. This award enhances students' competitiveness for future opportunities in hematology research.

The HIP Medical Student Award by the American Society of Hematology supports underrepresented medical students in hematology research. Participants gain mentorship, a stipend up to $32,000, and valuable exposure to hematology practices. The program offers summer, flexible, and yearlong project options to accommodate students at different stages of their medical education. This initiative aims to foster diversity in the field and encourage long-term involvement in hematology.

The Whole Foods Market Store Giving Program supports local communities by providing financial assistance to 501(c)(3) nonprofit organizations that focus on food access and environmental stewardship. This biannual program allows eligible organizations to apply via the Community Engagement Portal, although not all requests can be fulfilled due to high demand. Priority is given to those without recent funding, promoting sustainable community engagement.

The APA Congressional Fellowship offers psychologists a unique opportunity to engage in public policy, enhancing the application of psychological knowledge in government. Over a year, fellows work alongside Congress members, drafting legislation and participating in oversight activities. The fellowship is available for APA members, with stipends ranging from $75,000 to $90,000, in addition to health insurance reimbursement and professional development funds. This initiative aims to support psychologists interested in societal challenges and policy issues.

The CAO Legislative Crisis Grant, funded by the National Education Association Staff Organization, is designed to support affiliates in creating and refining student-centered initiatives. Grants can be utilized for contract campaigns, new program development, or enhancing existing practices to improve sustainable learning conditions. This opportunity is exclusive to affiliates, ensuring a focused approach to advocacy and collective bargaining efforts that benefit students.

The Student Research Fellowship Awards program provides financial support of up to $2,500 for students conducting research on Inflammatory Bowel Disease (IBD) for a minimum of 10 weeks. Aimed at undergraduate, medical, and graduate students, the initiative encourages research interest in IBD. Up to 16 awards are available, and research must be conducted under a qualified mentor at an accredited institution, ensuring a professional academic environment for the study of this critical health issue.

The Crohn’s & Colitis Foundation awards Research Fellowship Awards to support post-doctoral individuals pursuing innovative research in inflammatory bowel disease (IBD). With a maximum award of $70,000 per year for up to three years, the program encourages research aimed at understanding and preventing IBD progression. Eligible applicants must hold an MD or PhD and demonstrate relevant research experience. This initiative fosters the development of future independent researchers in the field of IBD.

The CareQuest Institute for Oral Health® is inviting proposals for school-based and school-linked initiatives aimed at improving oral health access for high-risk children. This grant opportunity seeks to address systemic barriers to oral health through innovative programs that engage schools and communities. Ideal projects may include workforce development, community engagement strategies, policy advocacy, and the use of technology. Proposals should focus on creating equitable oral health solutions that enhance both health and academic success for children and their families.

The Diversity, Equity, and Inclusion (DEI) Initiative Grant aims to promote innovative educational programs and enhance diversity within the nurse anesthesia profession. This grant supports efforts such as workshops, lectures, and online learning modules that address DEI issues. By funding these initiatives, the AANA Foundation seeks to foster an inclusive environment and advance the understanding of equity and diversity in the anesthesia community, benefiting both current and future practitioners.

The Henry Luce Foundation's Asia: Responsive Grants program supports initiatives that enhance understanding of East and Southeast Asia. With a focus on academic research, cultural exchange, and public education, the program seeks to promote collaboration between American and Asian institutions. Grants are awarded primarily to U.S.-based non-profits, fostering innovative teaching, resource development, and policy engagement, while prioritizing projects that bridge diverse disciplines and geographic divides.

The James S.T. Yao Resident Research Award encourages early-career physicians in the U.S. and Canada to engage in groundbreaking research on vascular diseases and therapies. Awarded by the SVS Basic and Translational Research Committee, it includes a $5,000 prize, a presentation opportunity at the Vascular Annual Meeting, and a subscription to the Journal of Vascular Surgery. This award honors the legacy of Dr. James S.T. Yao, a prominent figure in vascular research.

The Headache Medicine Fellowship aims to enhance training in headache medicine by supporting programs focused on diversity, equity, and inclusion. Targeting regions with workforce challenges, the fellowship encourages clinical practice, research, and education to address healthcare disparities. Preference is given to institutions that serve underserved populations and demonstrate a commitment to mentorship and expert guidance for fellows. This initiative seeks to improve understanding and treatment of headache conditions.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The Small City Program in Ohio allocates federal funds to small cities with populations between 5,000 and 24,999, not included in Metropolitan Planning Organizations. With an annual budget of $10.5 million, this program supports road, safety, and signal projects. The funding covers up to 80% of eligible construction costs, and a scoring system prioritizes projects based on various factors, ensuring effective use of resources and improved transportation infrastructure for eligible communities.

The Catholic School Leadership Development Grant Program aims to cultivate and retain promising leaders within the Catholic school system. In partnership with Loyola Marymount University, this initiative offers a graduate-level online Certificate in Catholic School Administration, covering 80% of tuition costs and providing funding for essential travel. The one-year program focuses on mission effectiveness, operational management, and instructional leadership, requiring participants to serve two years in their diocese post-completion, thereby enhancing local educational leadership.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

The AICEF Cultural Grant aims to enhance cultural ties between the United States and Indonesia by funding projects in the performing, visual, and literary arts. With grants ranging from $1,000 to $5,000, the foundation seeks to support distinguished individuals and groups whose work is accessible to the public and fosters goodwill between the two nations. This initiative not only promotes artistic excellence but also bridges cultural exchanges for a diverse audience.

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

The Wyandot County Community Foundation Grant supports organizations that effectively address the educational, cultural, health, social service, recreational, and economic development needs of Wyandot County. Grants range from $200 to $4000 and are awarded annually to eligible 501(c)(3) organizations and government units serving the area. The foundation prioritizes projects that demonstrate efficiency and broad community impact, while excluding regular operating funds and personal scholarships.

The OAR Community Grant aims to enhance the quality of life for autistic individuals by funding community-led projects that address physical health and support services. Grants ranging from $1,000 to $15,000 are available for initiatives designed to produce practical tools and resources. Eligible applicants include family members, autistic individuals, and community organizations committed to improving the lives of those affected by autism. Projects should be innovative, publicly accessible, and focus on priority topics such as health systems and community services.

The African-American Community Fund aims to enhance African-American participation in philanthropy, supporting diverse non-profits in the Dayton/Greater Miami Valley region. Grants typically range from $500 to $1,000, focusing on initiatives that promote community resource efficiency, coordination among organizations, and volunteer involvement. Eligible nonprofits must be 501(c)(3) tax-exempt entities with a diversity policy. The fund does not support general operations, individual pursuits, or endowments.

The John Lennon Endowed Scholarship, established by Yoko Ono to honor John Lennon, supports students attending UNCF member institutions. This initiative addresses financial need and promotes education among African American youth. With over $65 million awarded annually, UNCF empowers thousands of students, advocating for minority education and community engagement. Eligible applicants must have a minimum GPA of 3.0, complete a FAFSA, and demonstrate unmet financial need. This scholarship plays a crucial role in fostering future leaders.