Best Ohio Grants for Nonprofits

The Amcor Community Support Grants Program, administered by the Amcor Cares Foundation, provides funding for projects that benefit local communities. Grants are available to 501(c)(3) organizations and accredited educational institutions that serve Amcor Flexibles North America facility communities. Focus areas include fighting hunger, supporting disaster relief, expanding STEM education, and enhancing health and wellness. Applications are reviewed quarterly, and grant amounts typically exceed $1,000.

The American Electric Power Foundation provides grants to 501(c)(3) organizations focused on educational improvement, particularly in STEM fields, and basic human services such as hunger and housing. Organizations must operate within AEP's service territory or have a broader beneficial purpose. The Foundation also supports social justice initiatives and environmental protection efforts. Eligible applicants must affirm compliance with anti-discrimination policies and demonstrate commitment to diversity and inclusion.

The Amgen Foundation, established in 1990, focuses on enhancing science education and strengthening communities. It supports nonprofit organizations that align with its mission, emphasizing teacher development and hands-on science experiences. Grants are awarded annually, with a commitment of $180 million to impactful programs. Eligible organizations include public schools and libraries, while ineligible requests involve individual support, religious organizations, and political activities. This approach aims to inspire the next generation of innovators through quality educational opportunities.

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

CSX Charitable Investments provide essential in-kind donations to nonprofit organizations focused on supporting military members and community first responders. Through intermodal transportation services, CSX offers equipment and rail services to help reduce transportation costs for eligible organizations. The program also includes occasional donations of railroad materials and equipment based on availability. CSX prioritizes support for organizations operating within its service areas, promoting community betterment and development.

The Lubrizol Foundation Grants support nonprofit organizations that align with community investment priorities and the United Nations Sustainable Development Goals, focusing on quality education, health, and sustainable communities. Established in 1952, the foundation emphasizes support for initiatives in Cleveland, Ohio, and Houston, Texas. Grant applications are evaluated based on alignment with Lubrizol's investment pillars, with a commitment to fostering social impact and community well-being through financial support.

The Makulinski Family Foundation Grant supports nonprofit and charity organizations, emphasizing sustainable community development. With a commitment to lasting change, MFF actively matches investments to amplify their impact, ranging from 10:1 to 1:2 based on beneficiary needs. The foundation welcomes proposals from various regions, including Ohio, Michigan, and South Carolina, and encourages applications that align with their mission. Interested parties can access the grant request form to submit their proposals.

The McKesson Foundation Grant provides funding up to $25,000 for organizations focused on improving health outcomes in underserved communities. Established in 1943, the foundation prioritizes health equity through strategic partnerships aimed at reducing cancer burdens, preparing healthcare professionals, and enhancing crisis response efforts. Eligible applicants include national and local nonprofits targeting specific regions in the U.S. and Canada. The foundation emphasizes projects that align with its mission and demonstrate significant community impact.

The Amgen Foundation Inc focuses on non-healthcare donations and sponsorships that target humanitarian, social, educational, and community programs. They offer support to organizations outside the U.S. healthcare community, particularly those recognized as tax-exempt public charities. Eligible organizations must serve specific Amgen communities throughout the U.S. This initiative aims to enhance health outcomes and address critical societal needs, thereby reducing the burden of disease and improving lives.

The Republic Bank Grants program supports non-profit organizations in Kentucky, Indiana, Ohio, Tennessee, and Florida that enhance community welfare through various initiatives such as education, healthcare, and civic projects. By providing financial and in-kind donations, Republic Bank aims to strengthen community ties and foster impactful change. Eligible organizations must have IRS 501(c) status and submit grant requests in writing at least two months in advance, ensuring timely support for their initiatives.

The Valero Energy Foundation Grants support nonprofit organizations that align with their mission to improve the quality of life in communities where Valero operates. With a focus on basic needs, health care, education, and civic initiatives, the foundation prioritizes funding requests from 501(c)(3) organizations. In 2019, it provided approximately $40 million to support disadvantaged children and families, emphasizing a commitment to corporate citizenship and community well-being.

The Elevance Health Foundation's Maternal and Child Health Grant supports community-based nonprofit organizations aiming to enhance maternal and infant health outcomes. The foundation prioritizes funding programs that address disparities, improve care access, and promote health throughout the pregnancy journey. Focus areas include reducing pre-term birth rates and severe maternal morbidity. This initiative encourages scalable solutions for measurable impact across various states, ensuring comprehensive support for mothers and infants alike.

The Thomas J. Emery Memorial Grant, established by prominent Cincinnati philanthropists, aims to enhance the lives of individuals in the Greater Cincinnati area through grants that support social, cultural, educational, civic, and physical betterment. Founded in 1925, the grant prioritizes nonprofit organizations with IRS 501(c)(3) status, focusing on collaborative projects and impactful initiatives, while not providing ongoing operational support. This initiative honors the legacy of Thomas and Mary Emery in fostering community development.

The Joyce Foundation's Education & Economic Mobility Grants aim to close income and race disparities in college and career success. The foundation prioritizes equitable access to high-quality education, supporting policies for effective educators, high school graduation, and affordable college credentials. Focused on racial equity and economic mobility, it addresses the needs of historically underserved young people in the Great Lakes region and invests in research, policy development, and advocacy to help them recover from the COVID-19 pandemic.

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

• Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
• AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
• Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
• Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

• First place: $250,000
• Second place: $150,000
• Runners-up: $25,000
• Audience favorite: $75,000

The Cleveland-Cliffs Foundation, established in 1962, focuses on enhancing educational opportunities, environmental protection, and community health in the regions it operates. As a leading steel manufacturer, Cleveland-Cliffs is committed to sustainability and responsible corporate citizenship. The foundation supports 501(c)(3) organizations that address key challenges in education, the environment, and community well-being, ensuring impactful investments that help communities thrive across North America.

The Peoples Bank Foundation Grant aims to create a significant impact in local communities by providing financial support to nonprofit organizations. With over 20 years of service, the foundation has awarded more than $7.5 million in grants and scholarships across several states. It prioritizes initiatives that assist low to moderate-income individuals and families, encouraging organizations within its footprint to apply for funding to enhance their community-focused programs.

The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.

The ARISE Grants, offered by the Appalachian Regional Commission, aim to drive regional economic transformation across 13 Appalachian states. With funding of up to $63.5 million for implementation grants and $10 million maximum awards, the initiative supports collaborative projects that enhance community capacity and economic growth. The program encourages innovative partnerships to strengthen local economies and achieve socioeconomic parity, benefiting over 26 million residents in the Appalachian Region.

The American Honda Foundation provides programmatic support to nonprofit organizations and schools in the U.S., empowering impactful initiatives aligned with community needs. Funding opportunities are available through Honda corporate and Honda USA Foundation, focusing on projects that enhance education and community welfare. Eligible organizations must have nonprofit status or be recognized educational institutions. The application process opens each fall, with funding decisions announced the following spring, ensuring alignment with Honda's commitment to social responsibility.

The Fifth Third Foundation offers grants to nonprofit organizations in the Greater Cincinnati area, focusing on education, arts, community development, and health services. It aims to enhance community vibrancy and provide opportunities, supporting various funding interests from several benefactors. Eligible organizations must be 501(c)(3) nonprofits operating in Cincinnati, Dayton, or Northern Kentucky. The foundation prioritizes initiatives that empower women, support children, and promote environmental conservation, among other charitable purposes.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

The CenterPoint Energy Foundation aims to enhance community vitality through grants supporting affordable housing, environmental education, and workforce development. Focusing on low- to moderate-income populations, the Foundation prioritizes innovative programs that foster community connections and educational opportunities. By investing in both community vitality and education, they strive to create vibrant neighborhoods and empower individuals with the skills needed for success in today's workforce. Their commitment extends across Indiana, Minnesota, Ohio, and Texas.

The MGM Resorts Foundation Community Grant Fund supports nonprofit agencies providing essential services in areas such as affordable housing, education, and health. Grants are awarded for a one-year period and focus on regions where MGM Resorts employees live and work. Eligible applicants must comply with diversity policies and serve individuals or families. The foundation does not fund governmental agencies or projects exclusively for medical research. This initiative aims to enhance community well-being through targeted support.

The AmeriHealth Caritas Foundation Grant aims to prevent and mitigate adverse childhood experiences (ACEs) to promote healthier outcomes for children. With a focus on empowering families, healing behaviors, and access to healthcare, the foundation supports nonprofit organizations that provide comprehensive care and resources. Grants range from $100,000 to $250,000, totaling up to $1.945 million for project-specific initiatives. Eligible organizations must be 501(c)(3) nonprofits operating in states where AmeriHealth Caritas Medicaid markets exist.

The Needmor Fund for Social Justice aims to promote social justice by supporting community organizing efforts in the Midwest. With a focus on low- and moderate-income communities, BIPOC groups, and other marginalized populations, the fund provides grants for up to three years to organizations committed to long-term empowerment and advocacy. The initiative seeks to foster inclusive participation in democracy, ensuring that all voices are heard in shaping policies affecting their lives.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.