Best Osceola County Grants for Nonprofits in Iowa

Iowa Registered Apprenticeship Development Program (84F)

Supports newly established RA programs in high-demand fields.

The Iowa Registered Apprenticeship Development Program (84F) specifically provides funding for sponsors who create a new RA program in an eligible high-demand occupation or add a high-demand occupation to their existing program.

Available Funding

• $760,000

Awarded Amount

• One-time reimbursement of expenses incurred in establishing a registered apprenticeship program, up to a maximum of $25,000.

CDBG Downtown Revitalization

Supported by the federal Community Development Block Grant (CDBG) Program, these initiatives help communities reinvest in core commercial areas through coordinated improvements to both private building fronts and the public realm. Together, the programs advance HUD’s community development objectives by improving essential public facilities, enhancing local infrastructure, and supporting commercial revitalization within eligible downtown areas. Through targeted façade rehabilitation and transformative streetscape upgrades, the Downtown Revitalization Fund helps communities create safer, more inviting, and economically resilient downtown environments that benefit residents, businesses, and visitors alike.

Commercial Facades

The Commercial Facades Program assists communities with impactful downtown exterior improvement projects that eliminate slum and blight conditions.  

Projects include primarily front and highly visible side facades of commercial or mixed-use buildings in a traditional downtown setting.

The maximum grant amount is $650,000. Applicants must address blighted items on a minimum of eight buildings (addresses) to request a grant of $650,000 and a minimum of six buildings (addresses) to request anything less than the maximum.  

Project buildings must be situated within a downtown target area in which at least 25% of all buildings are determined to be in fair or poor condition. Determination of building status is made through individual surveys and documentation (pictures/ descriptions) demonstrating that the building is in fair or poor condition. A local funding match, typically from the city and the participating property owners, is required.

• New charter schools seeking authorization for the upcoming school year who also intend to apply for CSP funding
• Existing charter schools seeking to expand. Note that charters awarded CSP start-up funds are not eligible to apply for expansion funds. 

Start-up: Prepares new charter schools to open and operate.

Expansion: Grows high-quality EXISTING charter schools by raising enrollment or adding grades (program changes alone do not count).

Iowa Economic Development Authority

Mission

Strengthen economic and community vitality by building partnerships and leveraging resources to make Iowa the choice for people and business. Through two main divisions – business development and community development – IEDA administers several state and federal programs to meet its goals of assisting individuals, communities and businesses. IEDA works to achieve its mission and goals to benefit Iowans while maintaining a high level of transparency. 

Community Attraction and Tourism Grant

The Community Attraction and Tourism (CAT) program provides grant funds to assist projects that provide recreational, cultural, entertainment and educational attractions. The funds help communities create transformational projects that enhance the vitality of a region and the state overall. The CAT Grant Program is designed to assist communities in the development and creation of multiple-purpose attractions and tourism facilities. Funds must be primarily used for vertical infrastructure (land acquisition and construction, major renovation and major repair of buildings and recreational trails.)

Amounts or percentages from cities, counties, and private sources will vary by project, there is no minimum amount or percentage required.

Eligible projects must have 65% of financing/fundraising secured at time of the application. 

No more than 50% of the project can be funded by state dollars, including the amount awarded with CAT Fund funding.

Iowa Community Attraction and Tourism Fund Program

The Community Attraction and Tourism (CAT) Grant Program is designed to assist communities in the development and creation of multiple-purpose attraction and tourism facilities. The Program is governed by Iowa Code Chapter 15F, Subchapter II and 261 Iowa Administrative Code 211.

Iowa Economic Development Authority

Mission

Strengthen economic and community vitality by building partnerships and leveraging resources to make Iowa the choice for people and business. Through two main divisions – business development and community development – IEDA administers several state and federal programs to meet its goals of assisting individuals, communities and businesses. IEDA works to achieve its mission and goals to benefit Iowans while maintaining a high level of transparency. 

Opportunities and Threats Fund

A portion of Community Development Block Grant (CDBG) funds are reserved for communities facing an imminent threat to the public requiring immediate assistance. These funds may also be used by communities seeing an opportunity to demonstrate sustainable community activities.

The program is funded through the federal CDBG program. The goal of this program is to provide economic opportunities for people, especially those of low- and moderate income.

Health and Safety Threat Projects

• An immediate threat must exist to health, safety or community welfare that requires immediate action
• The threat must result from unforeseeable and unavoidable circumstances or events
• Must meet one of the three national objectives of the CDBG program
• No known alternative project or action would be more feasible than the proposed project
• Sufficient other local, state or federal funds (including the competitive CDBG program) either are not available or cannot be obtained within the time frame necessary to address the problem

Iowa Economic Development Authority

Mission

Strengthen economic and community vitality by building partnerships and leveraging resources to make Iowa the choice for people and business. Through two main divisions – business development and community development – IEDA administers several state and federal programs to meet its goals of assisting individuals, communities and businesses. IEDA works to achieve its mission and goals to benefit Iowans while maintaining a high level of transparency. 

Opportunities and Threats Fund

A portion of Community Development Block Grant (CDBG) funds are reserved for communities facing an imminent threat to the public requiring immediate assistance. These funds may also be used by communities seeing an opportunity to demonstrate sustainable community activities.

The program is funded through the federal CDBG program. The goal of this program is to provide economic opportunities for people, especially those of low- and moderate income.

Opportunity for Sustainable Community Activities

• Must meet one of the three national objectives of the CDBG program
• Consistent with sustainability and smart growth principles
• Provides a beneficial impact on the standard of living and quality of life of proposed beneficiaries
• Ready to proceed and be completed in a timely manner
• Leverages the maximum amount of local funds possible
• Will continue to remain viable after CDBG assistance
• Meets funding standards established by the minimum funding criteria set forth in the rule
• Applicants provide adequate information to Iowa Economic Development Authority (IEDA) on total project design and cost, as requested
• Innovative and could be replicated in other communities
• Meets or exceeds the minimum building and site design criteria established by the IEDA

Court Reporter Equipment Grant

Students enrolled in a court reporter training program in Iowa. The maximum award is up to $2,000 to reimburse students for the purchase of court reporter equipment and software for the court reporter training program.

Dennis Van der Meer Tennis Foundation

A 2021 International Tennis Hall of Famer, Dennis was the founder of the Professional Tennis Registry Foundation (PTR Foundation), now called Dennis Van der Meer Tennis Foundation, Professional Tennis Registry (PTR), and the Van Der Meer Tennis University.

Dennis Van der Meer Tennis Foundation is a nonprofit organization exempt from federal income tax under Section 501(c)(3) of the Internal Revenue Code. The Dennis Van der Meer Tennis Foundation provides support to deserving individuals and organizations globally. The foundation is also focused on bringing tennis within reach to countless people worldwide.

Nehemiah Atkinson Humanitarian Grant

This grant reflects the Foundation’s dedication to giving and serving others. It is awarded to individuals who have shown an extraordinary commitment to enhancing the lives of those around them.

The Foundation supports projects that promote and preserve the legacy, vision, and spirit of our founder, Dennis Van der Meer. We will only consider funding for educational, life enrichment, mentoring, and tennis programs.

Dennis Van der Meer Tennis Foundation

A 2021 International Tennis Hall of Famer, Dennis was the founder of the Professional Tennis Registry Foundation (PTR Foundation), now called Dennis Van der Meer Tennis Foundation, Professional Tennis Registry (PTR), and the Van Der Meer Tennis University.

Dennis Van der Meer Tennis Foundation is a nonprofit organization exempt from federal income tax under Section 501(c)(3) of the Internal Revenue Code. The Dennis Van der Meer Tennis Foundation provides support to deserving individuals and organizations globally. The foundation is also focused on bringing tennis within reach to countless people worldwide.

Natural Disaster Relief Request

The Foundation stands with tennis professionals affected by the devastating hurricanes and other natural disasters in the U.S. in 2024. If you are a tennis pro facing hardships due to recent storms, we are here to help you get back on your feet. Our assistance program provides relief and resources specifically for tennis professionals affected by these events. Together, we can rebuild stronger.

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Patient Travel Grant Program

A mesothelioma diagnosis and treatment often require the patient and their family to incur numerous expenses as part of their treatment. Travel to treatment, alone, can cause a significant financial burden on the patient, which might even cause the patient to not seek treatment away from home, even it’s their best option. To ensure that all patients have the ability to seek specialized help and treatments, the Mesothelioma Applied Research Foundation administers its Travel Grant Program.

The Meso Foundation’s Patient Travel Grant Program, founded by Mary and Bob Cosentino, provides travel grants to patients and one caregiver traveling for an initial consult and/or for clinical trial treatments.

• The type of eligible travel must fall into at least one of these two categories:
  • One trip for one initial consultation with a mesothelioma specialist.
  • Multiple trips to participate in an interventional clinical trial (found on clinicaltrials.gov).

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Bret A. Rosenthal Patient Assistance Fund

Patients diagnosed with cancer at a younger age often face greater financial burdens. This is a time in a patient’s life when they are raising a family, starting a career, or have not accumulated savings. For patients 49 and under, the Foundation administers the Bret A. Rosenthal Patient Assistance Fund grant program. This program is made possible by the generosity of the Rosenthal family.

Utilizing the Full Power of Empire AI Request for Applications

The Simons Foundation (SF) intends to support cutting-edge mathematics and basic science research, drawing on the advanced computational power of the Empire AI.

Toward this goal, SF plans to initiate a new program to fund six to 12 proposals through a competitive open call to the Empire AI research community.

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program. All submitted proposals should detail how their work will use multinode clusters of GPUs in Empire AI. Proposals focused on data curation and creation of datasets can be considered in exceptional cases, as long as the attained data will be used by the proposers for solving scientific problems as part of the same proposal.

The program’s total budget is expected to be $6 million USD over a two-year period.

Funding

Award Amount: There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Award Duration: June 1, 2027, through May 31, 2029.

Number of Awards: We expect to select six to 12 applications for funding.

The Affordable Rural Cooperative (ARC) Energy Program, initiated by the Rural Utilities Service (RUS), aims to enhance rural electric systems through substantial funding of approximately $175 million. This initiative focuses on increasing emission-free nuclear power and improving transmission infrastructure efficiency, promoting long-term reliability and affordability. Eligible entities include electric cooperatives serving rural areas and their subsidiaries. The program aligns with the Inflation Reduction Act (IRA) to achieve significant reductions in greenhouse gas emissions, thus fostering a sustainable energy future.

The Drexel Fund Founders Program is a one-year paid fellowship that helps outstanding leaders already on the path to launching a school continue to plan and open an innovative and effective private school in one of The Drexel Fund’s target states: Arizona, Florida, Indiana, Iowa, North Carolina, Ohio, Tennessee and Wisconsin. The tenth cohort of the Founders Program is designed for entrepreneurs who will begin the fellowship in Summer 2027 and be ready to launch a new private school in Fall 2028.Through the fellowship, school founders will develop their school’s education model and finalize the nuts and bolts of their school launch, including board and budget development, market analysis, facility location, student recruitment and staff hiring. Founders will create a plan that will make it possible for their school to achieve top-tier results for children while maintaining a sustainable financial model.

Greenawalt Foundation

Our Mission

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Community Grant

The Greenawalt Foundation extends its commitment to opportunity and well-being through community grants that support nonprofit organizations serving women, children, and vulnerable populations. These grants focus on programs that promote safety, stability, and self-sufficiency, including initiatives supporting domestic violence recovery, foster care, the working poor, and animal welfare. Foundation support strengthens the social fabric of communities and expands access to essential resources for those in need. Through these efforts, the Foundation helps build stronger, more compassionate communities where individuals and families can thrive.

Areas of Support

We focus our community grants on initiatives that align with our mission of compassion, opportunity, and empowerment. Areas of support may include:

• Domestic violence prevention and survivor support
• Programs for women and children
• Family assistance and poverty relief initiatives
• Foster care, youth development, and educational support
• Animal welfare and community-based rescue programs

Greenawalt Foundation

Building Stronger Communities

At The Greenawalt Foundation, we believe that opportunity is the foundation of prosperity. By supporting organizations that educate, train, and empower people in the trades, we’re helping to build a stronger, more sustainable future for all.

Skilled Trades Grant Opportunities

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Eligible Grant Categories

• Skilled Trades Training Support
• Pre-Apprenticeship or Apprenticeship Programs
• Youth Career Exploration Camps

Seeding Research, Networking, and Capacity Building at Minority-Serving Institutions

Introduction & Purpose

RWJF is committed to ensuring everyone has a fair and just opportunity to be as healthy as possible. To achieve this goal, we support research that examines the historical and systemic factors that cause health inequities. Some of those determinants are poverty, discrimination, and limited access to quality education, housing, safe environments, and healthcare. As attacks on data and academic freedom and ongoing funding cuts to federal health equity research and programs continue, philanthropy’s work to achieve fair and equitable health, including a more equitable research funding ecosystem, is more important than ever. While philanthropic support for Minority-Serving Institutions (MSIs) has increased in recent years, there is more to be done to rectify historical disparities in funding. 

This call for proposals (CFP) provides support to health equity research centers at MSIs to strengthen research infrastructure and capacity-building. Capacity-building will help develop staff, skills, culture, resources, and systems that enable research to happen effectively. Specific work that RWJF may fund under this CFP includes specific skill or methodology training; faculty release time; support for research assistants, advisors, and project staffing; mentoring, professional development and collaboration, and more.

Through this CFP, RWJF will expand its efforts to transform deeply rooted beliefs about which data and research methods are valued, whose perspectives are prioritized, and which populations deserve resources. By supporting the infrastructure and capacity-building needs of MSIs, this opportunity strengthens their ability to generate critical evidence and to cultivate transformative, actionable solutions toward health equity. 

RWJF believes in health equity research that is grounded in systems thinking; supports and disseminates evidence identifying and implementing structural solutions to racial and health inequities. This CFP seeks mission-aligned institutions to participate in cohort-style peer learning to advance their ability to engage in health equity research and apply for competitive funding opportunities in the future.

Although no single philanthropy can fill the gap left by federal funding cuts, this CFP demonstrates strong support for research, historically underrepresented researchers, and research centers that are positioned to pave the way toward a future where health is not a privilege, but a right.

The Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program, initiated in FY 2001, aims to foster collaboration between State and Federal entities in conserving listed species. This program provides funding for acquiring critical land parcels to support U.S. Fish and Wildlife Service-approved recovery plans. By securing habitats at risk from development, the initiative directly addresses the primary threat to endangered species, ensuring effective and immediate conservation actions.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of biological processes driven by somatic mutations in human tissues through innovative technology development. Since its inception in 2023, the program has produced multi-omic datasets from human tissues representing all germ layers. The NIH is now advancing to Stage 2, focusing on collaborative efforts to refine and implement validated technologies for somatic mutation detection and functional interpretation, promoting rigorous and cost-effective methodologies.

The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.

The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.

The GLS Campus Suicide Prevention program aims to enhance behavioral health services for college students, addressing critical issues such as suicide, depression, and substance use disorders. By fostering a culture of help-seeking and reducing stigma, this initiative ensures that at-risk students receive timely intervention and support. The program represents a vital investment in the mental well-being of students, promoting a healthier campus environment through evidence-based strategies and comprehensive public health approaches.