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Best Palo Alto County Grants for Nonprofits in Iowa

Looking for grants for 501(c)(3) nonprofit organizations working in Palo Alto County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.57B

Total funding

$5K

Median grant

9,000+ grants
$2.57B total
$5K median

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9,230 Results based on applied filters

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Funding

  • Individual projects requesting up to $50,000 USD will be considered. Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.
  • Maximum project length is 1 year.
Rare Diseases Hematological Systems

Iowa Training and Technical Assistance Competitive Grants

Iowa Department of Justice – Office of the Attorney General, Victim Assistance Section
State/Local Government
Iowa
Unspecified amount

Office of the Attorney General

The attorney general is the State of Iowa's chief legal officer. The attorney general has general charge, supervision and direction of the state's legal business. The Office of the Attorney General provides legal advice and representation to most of the state's major departments, boards, commissions, authorities, officials and institutions. The office further represents the State of Iowa in state administrative law and Iowa District Court matters, the Iowa Court of Appeals, the Iowa Supreme Court, lower federal courts and the U.S. Supreme Court.

Training and Technical Assistance Competitive Grants

The Victim Assistance Section of the Iowa Department of Justice (“Department”) seeks applications from qualified nonprofit organizations, community-based organizations, and governmental organizations to provide trauma-informed and victim-centered training and technical assistance in Iowa. 

Purpose

The purpose of this Notice of Funding Opportunity (NOFO) is to distribute state and federal funding to eligible applicants who will support victim services organizations, agencies within the criminal justice system and other organizations with training and technical assistance to promote healing, stability, and justice for those directly impacted by violent crimes, their families, and their communities

Project Period

The first year in the grant cycle is the competitive grant year. The following two grant years are continuing (non-competitive) grant years, subject to funding availability and program performance. 

Crime & Justice Crime Victim Services Police & Law Enforcement

Art Project Grants for Organizations - Creative Abundance Special Round

Iowa Economic Development Authority
State/Local Government
Iowa
US $15,000

About Us

Your centralized resource for business and community development information and programs from the Iowa Economic Development Authority and the Iowa Finance Authority.

Art Project Grant for Organizations Program Guidelines - Creative Abundance Special Round

The Art Project Grant for Organizations program is administered by the Iowa Arts Council, which exists within the Iowa Economic Development Authority (the IEDA). Through the program, the IEDA provides financial incentives to nonprofit and tax-exempt organizations; schools; local, county, state and federal governmental agencies; and tribal councils to support a wide variety of arts-related activities.

The program is funded through an appropriation by the Iowa Legislature to the IEDA and a grant by the National Endowment for the Arts, a federal agency. Applicants must comply with federal requirements, including but not limited to 2 CFR Part 200.

Disability Care & Services Arts / Culture Access & Participation Art Education +2 more

EMS System Development and Sustainability Assessment Grant

Iowa Department of Health and Human Services
State/Local Government
Iowa
Up to US $2,000,000

645598 - FY26 RFP PHTHOET26001 for EMS System Development and Sustainability Assessment

Funding Opportunity Details

Description

The issuance of this Funding Opportunity in no way constitutes a commitment by Iowa HHS to award a contract.

The purpose of this Request for Proposal (RFP) # PHTHOET26001 is to solicit applications that will enable the Iowa Department of Health and Human Services (referred to as Agency) to select the most qualified applicant to provide a statewide EMS System Development and Sustainability Assessment. This assessment will inform the design and implementation of a district-based hub-and-spoke EMS model to improve access, coordination, and sustainability of emergency medical services in rural Iowa. This work implements a portion of the Community Care Mobile initiative of the Iowa Healthy Hometowns Project, funded through the Centers for Medicare & Medicaid Services’ Rural Health Transformation Program, opportunity #: CMS-RHT-26-001

Emergency Medical Care & Services Rural Health Care

George and Viola Hoffman Award

American Association of Geographers
Association/Society
United States
Up to US $500

An award from the George and Viola Hoffman Fund may be made annually for student research toward a master’s thesis or doctoral dissertation on a geographical subject in Eastern Europe. Eastern Europe includes the countries of East Central and Southeast Europe from Poland south to Romania, Bulgaria, and the successor states of the former Yugoslavia. Topics may be historical or contemporary, systematic or regional, limited to a small area or comparative.

Geography

F26AS00104 State ANS Management Plan 2026

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $5,000 - US $150,000
The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.
Ichthyology (Fish) Limnology Fisheries +1 more

Child Protection Compact Annual Program Statement (362907)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $5,000,000 - US $10,000,000
The Child Protection Compact Annual Program Statement invites proposals aimed at combating child trafficking through collaborative efforts between the United States and other countries. This initiative focuses on enhancing the capacity to prosecute traffickers, providing care for victims, and implementing preventive measures. Organizations interested in applying must align with the objectives of the CPC to ensure comprehensive support and effective intervention against all forms of child trafficking.
Child Welfare Services Human Trafficking

TIP Office International Programs to Combat Human Trafficking Annual Program Statement (362906)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $10,000,000
The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.
Human Trafficking

Enrich Iowa: Direct State Aid Grant

State Library of Iowa
State/Local Government
Iowa
Unspecified amount

About the State Library

Mission:

The State Library of Iowa strengthens Iowa library services and information access for Iowans.

Enrich Iowa

About Enrich Iowa

The State Library annually administers funding appropriated by the Iowa Legislature to libraries in Iowa. Enrich Iowa consists of three programs to aid libraries in offering improved service to Iowans:

More About Direct State Aid

Direct State Aid funding is distributed to participating public libraries through a formula that calculates:

  • A base amount dependent on Tier Level met, as set by the Accreditation & Standards program.
  • The per capita amount based on the population of the city and level of compliance with quality measures.
  • Three percent of the amount of funding received by the library in the previous fiscal year for service to rural residents and contracting communities.
Library Services

DOW Combat Readiness – Medical Research Program Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,450,000
The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.
Crisis Intervention Post-Traumatic Stress Disorder

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

Childhood Asthma in Urban Settings Clinical Research Network

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.
Respiratory Diseases & Systems Asthma

BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.
Neuroscience

AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) (362945)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.
HIV / AIDS

Collaborative Network for Clinical Research on Immune Tolerance

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.
Infectious & Parasitic Diseases Immune System Diseases

Clinical Data, Safety and Statistical Centers (CDSSC)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.
Immune System Diseases Allergies & Allergic Diseases

Translational Transplantation Tolerance Cooperative Study Group

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.
Infectious & Parasitic Diseases Organ And Tissue Banks

Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.
Health & Medicine Infectious & Parasitic Diseases Chronic Illnesses

Asthma and Allergic Diseases Cooperative Research Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.
Respiratory Diseases & Systems Asthma

Clinical Trials in Organ Transplantation in Children and Adults

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.
Infectious & Parasitic Diseases Organ And Tissue Banks

Translational Centers Using Microphysiologic Systems for Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.
Infectious & Parasitic Diseases

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $10,000 - US $40,000

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

  • Training programs
  • Programs that engage new adopters and grow the market share for adoption
  • Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
  • Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

  • Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
  • Decrease length of stay
  • Decrease cost of care
  • Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

Animal Welfare - General Animal Welfare - Domestic Animals & Pets

Global Health, K-12 STEM Education and Economic Mobility Grant

Eli Lilly And Company Foundation
Private
United States
Unspecified amount

Lilly Foundation

To extend Lilly’s charitable reach and impact, the Eli Lilly and Company Foundation (Lilly Foundation) was established in 1968 and is supported by donations from Eli Lilly and Company.

The Foundation is a tax-exempt, private foundation supporting programs that align with its philanthropic priorities.

Grantmaking Approach

The Lilly Foundation’s work is guided by a charitable vision of a world where every person has an opportunity to live their healthiest life. Through grantmaking focused on Lilly Foundation’s charitable vision, grants can serve as a catalyst for closing gaps and empowering individuals and communities to thrive.

All proposals should demonstrate clear alignment with at least one focus area and include charitable outcomes that are measurable and consistent with the Foundation’s long-term charitable goals.

Global Health, K-12 STEM Education and Economic Mobility Grant

Focus Areas

Global Health

Lilly Foundation, through its charitable grants, aims to support permissible charitable efforts to improve access to quality healthcare for resource-limited communities in low- and lower-middleincome countries (L/LMICs) and in the United States. Strengthening access to care is essential for enhancing community well-being and supporting economic stability in resource-limited settings.

The Global Health focus area aims to close gaps in quality healthcare by supporting charitable solutions that improve access, bring care closer to where people live, and address the high burden of non-communicable diseases (NCDs) in resource-limited settings. To the extent permissible, the Foundation prioritizes charitable efforts related to cardiometabolic health in resource-limited settings.

K-12 STEM Education

The K-12 STEM Education focus area aims to close the gaps for students from low-income communities by supporting programs that foster new pathways and pipelines to STEM education through focused K-12 efforts, concentrating on the critical middle school years. The Foundation’s K-12 STEM Education grants are focused on initiatives that benefit Marion County, Indiana.

Economic Mobility

The Economic Mobility focus area supports charitable and educational programs that strengthen workforce readiness, postsecondary and skills-based educational pathways, and housing stability to promote long-term prosperity. This support is focused on Marion County, Indiana, with the goal of improving economic opportunity for low-income communities and advancing community well-being.

Health Disparities & Social Determinants of Health Community Health Education Nutrition & Healthy Eating +9 more

Zero Electrocution Challenge Grant

McElhattan Foundation
Private
U.S. Territories, United States
Up to US $1,000,000

About McElhattan Foundation

Founded in 2017 following the sale of Industrial Scientific Corporation, McElhattan Foundation invites bold ideas that advance the goals of its four program areas, including Ending Death on the Job.

Zero Electrocution Challenge

Despite decades of regulations, training, and personal protective equipment, workers continue to die from electrical contact every year.

McElhattan Foundation’s Zero Electrocution Challenge seeks breakthrough solutions that present pathways to eliminate life-threatening tasks that lead to fatal electrocution on the job by the year 2050, while increasing enterprise profitability and productivity. This is the inaugural ZERO 2050 challenge, awarding two Winners up to $1 million each.

Occupational Health & Safety Electrical Engineering

Greenlight Grant

Iowa Economic Development Authority
State/Local Government
Iowa
US $10,000 - US $50,000

Greenlight Grant

Greenlight Grants are intended to provide entrepreneurial and collaborative Iowa filmmakers with a financial boost to launch a well-written script to screen and the opportunity to stretch creatively, think big and tell an important story that needs to be told to a larger audience. A goal of the Program is for Iowans to become job creators that grow our film and media industry.  

Through the Program, the IEDA provides financial incentives to Iowa filmmakers who are ready to produce films and media projects that can take them to the next level in their careers and contribute to a more robust film and media industry and creative economy in Iowa.   

The Greenlight Grant is administered by the Iowa Arts Council and Produce Iowa within the Iowa Economic Development Authority. The program is funded through an annual appropriation by the Iowa Legislature. 

Film Media Arts Job Creation +1 more

Special Program Announcement for Office of Naval Research Research Opportunity: FY27 Communications and Networking Applied Research

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
United States
US $250,000 - US $500,000
The FY27 Communications and Networking Applied Research program aims to advance technologies essential for Naval operations. This initiative aligns with the Design for Maritime Superiority, focusing on the Naval Tactical Grid (NTG) to ensure seamless connectivity among distributed units. The technologies developed will operate under challenging conditions across multiple domains, enhancing command and control capabilities for effective decision-making in maritime and other operational theaters.
Military Operations Emerging Technology Development Cyberinfrastructure

Fair Housing Initiatives Program Private Enforcement Initiative (362827)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
United States
US $250,000 - US $500,000
The Fair Housing Initiatives Program (FHIP) aims to combat discriminatory housing practices through funding provided to various organizations. Established by Congress in 1988 and made permanent in 1992, FHIP supports entities that educate the public and enforce fair housing rights. The program offers competitive grants across four initiatives, including the Private Enforcement Initiative, which enables national non-profit organizations to investigate violations and uphold fair housing laws effectively.
Civil Rights Real Estate & Housing Equitable & Affordable Housing +1 more

Palo Alto County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Palo Alto County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Iowa

Average Grant Size

What's the typical amount funded for Iowa?

Grants are most commonly $82,635.

$82,635

Total Number of Grants

What's the total number of grants in Palo Alto County Grants for Nonprofits year over year?

In 2024, funders in Iowa awarded a total of 28,032 grants.

2022 25,336

2023 26,582

2024 28,032

Top Grant Focus Areas

Among all the Palo Alto County Grants for Nonprofits given out in Iowa, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Palo Alto County Grants for Nonprofits changing over time?

Funding has increased by 9.41%.

2022 $2,079,026,768

2023 $2,108,613,200
1.42%

2024 $2,307,128,111
9.41%

Iowa Counties That Receive the Most Funding

How does grant funding vary by county?

Polk County, Story County, and Johnson County receive the most funding.

County Total Grant Funding in 2024
Polk County $545,560,005
Story County $266,280,101
Johnson County $184,865,698
Linn County $166,016,288
Boone County $155,314,892

Related Grants in Iowa

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