Best Grants for 501(c)(3) in Pennsylvania

The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.

MileOneCares offers community grants aimed at enhancing lives through improved access to transportation and community support. Non-profits with 501(c)(3) status, operational for two years, can apply for funding to address local needs. The program prioritizes initiatives that uplift youth and the elderly in underserved areas. Applications are accepted year-round, but those for the current calendar year must be submitted by November 8. Grants do not support endowments or individuals.

Our Mission

The Baughman Family Foundation aims to make an impact on our local communities by supporting organizations nominated by family members. The goal of the foundation is twofold: to make a meaningful impact on our selected charitable organizations and to encourage family members to become active in charitable giving.

Submission Guidelines

When submitting an application, please keep the following guidelines in mind:

The focus of the Baughman Family Foundation is on supporting local charities where the Foundation can make a direct, tangible impact on causes that matter to our family.

The Graduate Education Fund: AUKUS Scholarships, established by the American Australian Association, supports American and Australian citizens pursuing full-time graduate studies in security, technology, and diplomacy. With up to $40,000 in funding for tuition and living expenses, this scholarship encourages innovative research in critical fields, particularly in relation to the AUKUS initiative. Applications are open biannually, fostering educational exchange and collaboration between the two nations.

The Rural Communities Opioid Response Program focuses on enhancing behavioral health care services for children and adolescents in rural areas. By providing essential funding, this initiative aims to tackle mental health and substance use disorders, ensuring that young individuals receive the support they need. The program, administered by the Health Resources and Services Administration, is crucial in addressing the unique challenges faced by rural communities, promoting healthier outcomes for future generations.

The Mitsubishi Corporation Foundation for the Americas (MCFA) supports environmental initiatives across the Americas, focusing on biodiversity conservation, environmental education, justice, and sustainable development. They prioritize programs that align with these aims, particularly those involving 501(c)(3) organizations. MCFA seeks to empower marginalized communities, promote ecological stewardship, and encourage sustainable economic practices, ensuring that environmental burdens are shared equitably across all communities.

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

• Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
• AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
• Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
• Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

• First place: $250,000
• Second place: $150,000
• Runners-up: $25,000
• Audience favorite: $75,000

The HEAL initiative focuses on translating addiction research into practice, targeting the opioid crisis and overdose events. It emphasizes action-oriented research to identify barriers and facilitators in substance use treatment and prevention. The initiative seeks effective and scalable approaches to implement evidence-based interventions across various care settings. Collaboration among experts in health economics, implementation science, and addiction recovery is encouraged to foster innovative solutions. This Notice of Funding Opportunity allows time for applicants to develop impactful projects.

The Homeless Veterans' Reintegration Program (HVRP) aims to assist veterans experiencing homelessness by providing tailored employment services. This federal initiative focuses on helping veterans transition to stable employment through job training, case management, and connections to local supportive services. HVRP aligns with national priorities to enhance career outcomes for veterans, ensuring they receive the necessary tools and resources for sustainable employment and integration into the workforce.

The Principal Student Support Services Grant, offered by the School-Based Healthcare Solutions Network, aims to enhance mental health support for students in grades 6-12 at under-resourced public schools. With funding available for hiring mental health professionals and performance-based awards, this initiative addresses critical challenges like chronic absenteeism and behavioral issues. By providing targeted interventions, the grant seeks to improve academic performance and overall well-being among students facing mental health crises.

The Dr. Alice M. Hudder- Richard T. Molder Post-Secondary Scholarship Fund, established by Richard Molder, supports Erie County high school seniors pursuing post-secondary education. In 2023, the Erie Community Foundation awarded over $800,000 in scholarships to deserving students. Two awards will be granted: one for students focusing on science, math, or business, and another for those studying art or music, emphasizing financial need and a strong work ethic.

The Agriculture Innovation Center Grant Program aims to support Agriculture Innovation Centers by providing grants that facilitate technical assistance to agricultural producers. This initiative focuses on enhancing the marketing of value-added agricultural products, ultimately fostering growth in the agricultural sector. Funded by the USDA's Rural Business-Cooperative Service, this program is designed to empower producers and promote innovation in agricultural practices.

The Centre Gives Program is an annual 36-hour online giving event hosted by the Centre Foundation, taking place on May 14-15, 2025. This initiative encourages community donations, allowing donors to support local nonprofits while amplifying their contributions through matching funds and prizes. Since its launch in 2012, over $12.5 million has been raised for more than 190 organizations in various sectors, including education and health, fostering community engagement and support.

Pershing Square Lotus Award for Ovarian Cancer Research

The Pershing Square Foundation (PSF) has worked across sectors to catalyze innovative approaches to the most difficult problems. Talented individuals have always been at the center of our approach. We aim to support leaders who transform systems, embrace new paradigms, and have an innate drive to make an impact.

PSF has funded pioneering cancer researchers through the Pershing Square Sohn Cancer Research Alliance for over a decade and supported women’s health initiatives in New York City. Through this Request for Proposals (RFP), PSF aims to combine these two priority areas of women’s health and cancer to shine a light on one of the most understudied and underfunded cancers—ovarian cancer. Ovarian cancer is the deadliest gynecologic cancer, with 80% of women diagnosed at an advanced stage. Only 27% of women diagnosed during an advanced stage survive for five years. Ovarian cancer remains a disease with a poor prognosis due to limited early detection and treatment options.

PSF supports research efforts by 

• deploying capital quickly, 
• funding high-risk, high-reward ideas, 
• bringing new perspectives into a field, 
• encouraging collaboration, and 
• leveraging our vast network. We challenge our scientific partners to think creatively and across silos, to spur innovation to fight ovarian cancer.

Through the Pershing Square Lotus Award for Ovarian Cancer Research, PSF is looking for investigators who are either already working on a promising project in ovarian cancer or in another type of cancer that could have an impact on ovarian cancer. Grantees each receive $250,000 a year for three years, totaling $750,000.

Researchers who are not studying ovarian cancer are encouraged to apply and required to find a collaborator with experience in ovarian cancer research.

This award aims to 

• inspire investigators with unique expertise to apply their knowledge to ovarian cancer and 
• empower ovarian cancer researchers to pursue their boldest, most innovative ideas. Facing a disease where too few have survived to-date, PSF ultimately aims to create a culture around ovarian cancer that offers women hope, akin to the breast cancer community. PSF is passionate about changing outcomes for tens of thousands of women a year and is hopeful that future scientific discoveries will allow for more survivors who can share their stories for years to come.

The Susie Kubié Symphonic Music Scholarship, established in 2017, provides financial support to talented young musicians from the Albuquerque Youth Symphony Program (AYSP). Each year, up to $4,000 is awarded to new or renewing scholars pursuing a music degree. Applicants are required to submit a personal essay, letters of reference, and a video performance. This scholarship not only aids students in their educational pursuits but also honors Susie Kubié's legacy of dedication to music education.

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Planning and Demonstration Grants

Planning and Demonstration Grant Eligibility Requirements

Eligible activities for a Planning and Demonstration Grant include: develop a new Action Plan, conduct supplemental safety planning to update an existing Action Plan, or carry out safety demonstration activities to inform the development of or update to an Action Plan.

These activities may be bundled in any combination, provided that the requirements in this Notice are met. DOT encourages complementary but distinct activities, including but not limited to safety demonstration activities that will help inform the development of an Action Plan. Any applicant that meets the eligibility requirements may apply for a Planning and Demonstration Grant to develop an Action Plan. 

• Expected number of awards: 400 to 700

Oregon Department of Forestry

Vision: Complex and resilient forest ecosystems that endure and adapt.

Mission: To protect and promote resilient forests that benefit all Oregonians.

US Dept. of Transportation Grant - Safe Streets and Roads for All (SS4A) Grant Program

The purpose of this Notice of Funding Opportunity is to solicit applications for Safe Streets and Roads for All (SS4A) grants.

Funds for the fiscal year (FY) 2026 SS4A grant program are to be awarded on a competitive basis to support planning, infrastructural, behavioral, and operational initiatives to prevent death and serious injury on roads and streets involving all roadway users, including pedestrians; bicyclists; public transportation, personal conveyance, and micromobility users; motorists; and commercial vehicle operators.

The SS4A Grant Program includes: 1) Planning and Demonstration Grants; and 2) Implementation Grants.

Implementation Grants

Implementation Grants fund projects and strategies identified in an Action Plan that address roadway safety problems. Implementation Grants may also fund supplemental planning and demonstration activities, as well as project-level planning, design, and development activities for projects and strategies identified in an Action Plan (e.g., project-level 21 National Environmental Policy Act (NEPA) compliance, associated environmental review activities, permits and approvals, construction design, etc.). 

• Expected number of awards: 40 to 70

The Furer-Barag-Wolf Post 126 Jewish War Veterans Scholarship Award supports children or grandchildren of JWV Post 126 members, providing merit-based assistance for college or vocational education. Eligible applicants must reside in specific counties in New Jersey or be related to a JWV member. The scholarship covers tuition, books, and living expenses and is open for reapplication annually. This initiative by the Jewish Community Foundation fosters educational opportunities for deserving students.

The HEAL Initiative offers Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01), targeting early career researchers and clinicians. This program emphasizes training in implementation science methods to tackle opioid use disorder and enhance recovery support services. By fostering expertise in these areas, the initiative aims to combat the overdose crisis and cultivate future leaders in addiction research and clinical practice.

The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.

The Building Hope: Future Forward Schools Prize & Fellowship Program aims to enhance career exploration for middle and high school students. This initiative, launched by Building Hope in partnership with American Student Assistance, recognizes schools that excel in career-connected learning. Awardees receive funding, mentorship, and resources to empower students from diverse backgrounds, ensuring they develop essential skills for future success. With $50,000 available for five schools, this program fosters innovation and prepares students for a changing economy.

The Southern NM Down Syndrome Families Scholarship Fund Endowment aims to provide financial support for individuals with Down syndrome pursuing post-secondary education or life skills training at accredited institutions. Managed by the Community Foundation of Southern New Mexico, this scholarship embodies the mission of improving quality of life and fostering educational opportunities for diverse communities. It encourages applicants from various backgrounds, including those with disabilities, to achieve their academic and personal goals.

The NAMM Foundation Global Grantmaking Program provides music research grants aimed at enhancing music education and career mobility. With a focus on eliminating barriers for underrepresented communities, grants range from $5,000 to $25,000. The foundation supports high-impact organizations that demonstrate measurable outcomes and align with its mission of fostering music makers. Eligible applicants include those with a strong research track record and innovative project proposals that do not duplicate existing studies.

The Nancy Talbot Postdoctoral Research Fellowship, established by the American Occupational Therapy Foundation, offers $30,000 for one year to support postdoctoral research in occupational therapy. This fellowship aims to enhance diversity in the field by funding individuals from underrepresented racial and ethnic groups, as identified by the NSF. Eligible candidates must hold an OT degree or relevant doctorate, have a mentor, and conduct research at a U.S. academic institution.

The Walking Classroom Grant Program, offered by the Alliance for a Healthier Generation, enables classroom teachers in public schools to receive donated materials for their students. This innovative program promotes physical activity while maintaining instructional time through engaging podcasts. Ideal for grades 3-8, it enhances cognitive function and retention. Schools with the greatest need, both socioeconomically and academically, are prioritized, ensuring that all students can benefit from this unique educational approach.

The See, Test & Treat Grant offers vital funding for cancer screening and health education programs targeting medically underserved communities. This pathologist-led initiative aims to reduce healthcare barriers, empower preventive care, and connect patients with local resources. Eligible organizations can apply for up to $50,000 over three years, fostering sustainable health improvements. The program emphasizes same-day results for screenings and culturally appropriate education, ensuring equitable access to essential healthcare services.

The Best Buy Teen Tech Center is offering a Mini Tech Skills Workshop Grant to support local and national non-profits in providing STEAM skills workshops for youth aged 13-19. These workshops, which include topics such as coding, filmmaking, and robotics, aim to enhance technical skills and career exploration. Funding can reach up to $24,999, with a focus on hands-on, facilitator-led experiences, and additional programming opportunities may be considered.