Best Financial Assistance Grants in Puerto Rico

The DARRP Restoration Implementation Grants aim to enhance marine and coastal habitat restoration through collaboration between NOAA and non-federal partners. These grants address oil spills and hazardous substance releases by supporting restoration activities authorized under various environmental laws. Eligible applicants will implement projects that promote sustainable fisheries, recover endangered species, and boost local economies. Through careful planning and evaluation, recipients will contribute to effective restoration strategies that align with NOAA's mission and the needs of coastal communities.

The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.

The Pulitzer Center Rainforest Reporting Grant supports journalists reporting on critical issues in tropical forests, particularly in the Amazon, Congo Basin, and Southeast Asia. This grant encourages innovative and collaborative proposals while providing essential resources and training. Grants typically range from $8,000 to $15,000, focusing on underreported topics that connect local and global perspectives. The initiative emphasizes transparency, governance, and in-depth reporting to combat illegal wildlife trade and harmful extraction practices.

The Alzheimer's Disease Programs Initiative (ADPI) aims to foster the development of dementia-capable community health worker programs within the National Aging Network. This initiative, supported by the US HHS: Administration for Community Living (ACL), seeks to enhance dementia screening, reduce barriers to care, and improve access to essential services for individuals with dementia and their caregivers. By integrating community health workers into aging services, the program aspires to elevate the quality of life for those affected.

The Centers for Structural Biology of HIV and Other Infectious Diseases aims to support innovative frontier science research that establishes new technologies and methodologies to provide insight into the mechanisms of hostpathogen interactions, as well as translational research to inform the development of novel and/or improved preventive interventions, therapeutics, diagnostics, and curative interventions across a broad spectrum of infectious diseases. These Centers focus on understanding the dynamics of molecular complexes, with the intention of informing mechanistically based discovery and/or design of interventions for the prevention, treatment, and cure of HIV and other infectious diseases. The goal is to facilitate the discovery of new therapeutic targets, new classes of interventions ranging from diagnostics, to small molecules and protein therapeutics, to neutralizing antibodies, and novel vaccine candidates, including nanoparticle vaccines, elucidate the mechanisms of action of interventions, and to determine the structural basis for interventional failures, but not support end-to-end preclinical development.

Of particular interest are the components of infectious agents and/or hosts for which sufficiently complete structureshave yet to be determined, including macromolecular complexes of proteins, nucleic acids, carbohydrates, lipid membranes, and/or small molecules. The Centers will be responsible for the validation of structural data using biological, biochemical, and computational methods and artificial intelligence (AI) models to help understand the biological mechanisms and structure-function relationships of these complexes.

The Sorenson Legacy Foundation Grant aims to improve lives through support for education, health care, community development, and innovation. Established by James and Beverley Sorenson, the foundation focuses on enhancing art education, medical technologies, and community assistance in Utah. It prioritizes projects that foster artistic growth, promote innovative solutions, and address health care challenges while aiding vulnerable populations. The foundation's commitment to enriching lives reflects a deep-rooted belief in the power of education and community engagement.

The Rural Communities Opioid Response Program - Overdose Response aims to enhance healthcare access in rural areas by addressing urgent needs related to substance use disorder services. This initiative focuses on reducing overdose risks through targeted interventions and support, ensuring that rural communities receive necessary assistance. Funded by the Health Resources and Services Administration, this program is crucial for mitigating the opioid crisis in underserved regions, improving health outcomes, and promoting overall community well-being.

The NIH R25 program aims to enhance inclusivity in the substance use and addiction research workforce by supporting educational activities for individuals from diverse backgrounds. This initiative focuses on skill development courses and research experiences, encouraging underrepresented groups to pursue careers in biomedical and behavioral sciences. By fostering an inclusive environment, the program seeks to promote diversity in research and improve outcomes in health-related fields. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged.

The Therapeutic Giving program from Johnson & Johnson Innovative Medicine aims to support local and regional organizations focused on improving patient access to treatment and advancing health equity. Eligible applicants include 501(c)(3) nonprofit organizations, with funding preferences for programs that address significant healthcare disparities, mental health initiatives, and innovative solutions with measurable outcomes. The application period for local organizations runs from March 1 to May 31, while national organizations can apply in September.

The Therapeutic Giving initiative by Johnson & Johnson focuses on funding programs in neuroscience aimed at enhancing patient access to treatments and promoting health equity. Nonprofit organizations classified as 501(c)(3) can apply for support from March 1 to May 31. The initiative emphasizes innovative, measurable programs in areas like Alzheimer’s disease and mental health, prioritizing those that address healthcare disparities and improve quality of life for affected individuals.

The Therapeutic Giving: Oncology program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatments and services, promote health equity, and strengthen healthcare workforces. It supports programs that raise disease awareness, empower patients, and improve health systems with measurable outcomes. Eligible applicants include nonprofit organizations with 501(c)(3) status, emphasizing innovative programs addressing healthcare disparities and unmet needs.

The NIH is offering access to biospecimens from the ABCD, HBCD, and PATH studies to promote research on health and disease across a lifetime. This initiative encourages projects that utilize these samples to deepen understanding of genetic and environmental influences, particularly substance exposure. Researchers can submit proposals to maximize the scientific utility of these resources, in alignment with the goals outlined under federal health regulations.

The Rural Opioid Technical Assistance Centers program aims to provide vital training and technical assistance to combat opioid and stimulant misuse in rural areas. With ten regional centers and a national coordinating office, the initiative focuses on high-quality prevention, treatment, and recovery support services for substance use disorders, including polysubstance use. The program anticipates awarding 11 new grants to enhance community support and reduce substance-related challenges.

The Doyle Undergraduate Fellowship, offered by New Hampshire Sea Grant, provides a unique opportunity for undergraduates to engage in marine resource projects while receiving mentorship and training. This paid fellowship supports students interested in marine-related research and education, with potential earnings of up to $5,000 over a 10-week summer period. By participating, fellows gain valuable insights into coastal and marine management, enhancing their skills and expanding their professional networks.

The NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) supports high-risk, investigator-initiated studies aimed at diseases within NIDDK's mission. This two-part process allows for early peer review and assessment of study design and protocol, as well as support for essential documents and elements necessary for conducting the study. Applicants are encouraged to consult with NIDDK staff prior to submission.

Funding Innovative Research

Cannonball Kids’ cancer Foundation (CKc) prioritizes funding clinical trials, research that is nearing translation to a clinical trial, and young investigator grants.

Grants funded by CKc must be innovative and provide better quality of life or symptom relief than current treatments. 

When possible, CKc will prioritize funding research:

• with a focus on cancers that are under-funded or under-researched,
• with a focus on patient populations who are traditionally underserved.

When possible, CKc will prioritize funding researchers of diverse backgrounds.

For CKc, “innovation” means the invention or application of novel methods or treatments, specifically treatments that have fewer side-effects than standard care, increase a child’s quality of life, and/or create an option for care where there otherwise were few or none (either on primary diagnosis, relapse, or for recalcitrant cancers).

Research Grants

Grant Program: Clinical Trial

$200,000 over 3 years

• PI must hold an academic appointment at the Assistant Professor level or higher
• Preclinical studies must be complete
• If an FDA Investigational New Drug (IND) application is necessary for the proposed clinical study, the IND application should already have passed FDA initial review and be active
• If the PI has recruited additional patient enrollment sites, local IRB approval must be obtained for each site.

• How many treatment options would this study provide for children?
• How accessible is this study for children and families to access?

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The Core State Injury Prevention Program (Core SIPP) aims to enhance public health infrastructure and partnerships to prevent unintentional injuries through data-driven strategies. Focusing on key areas such as traumatic brain injury, falls among older adults, and drowning, it seeks to improve community safety by strengthening data use and fostering collaborations. This initiative supports states in identifying local injury concerns, thus promoting evidence-based prevention approaches and increasing the capacity for sustained public health actions.

The Smart Growth America Community Connectors Grant Program supports small and mid-sized cities in addressing divisive infrastructure caused by dangerous roads. With funding from the Robert Wood Johnson Foundation, this program aims to reconnect communities through temporary street safety projects while fostering skills and partnerships. Eligible teams must represent populations of 50,000 to 500,000 and include both government and community-based organizations. Priority will be given to projects benefiting low-income communities historically affected by disinvestment.

The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

This NOFO invites applications for time-sensitive research aimed at evaluating policies affecting health behaviors and chronic disease risks, particularly related to obesity. The initiative emphasizes the importance of swift funding decisions to capitalize on unique research opportunities that arise from new policies. Successful applications will be funded within four months of submission, provided they demonstrate a compelling need for expedited evaluation. This funding aims to significantly impact obesity prevention efforts through timely research.

The U.S. Healthcare Donations program by Amgen aims to support not-for-profit organizations in the healthcare sector. As a leading biotechnology company, Amgen provides funding for initiatives that improve science, technology, education, and public awareness on medical conditions. Organizations eligible for funding must be tax-exempt entities, focusing on genuine philanthropic efforts that align with Amgen's mission to enhance health outcomes and reduce the burden of diseases.

Hispanic Heritage Foundation

Established by the White House in 1988, the Hispanic Heritage Foundation—a 501(c)(3) nonprofit organization—continues to advance its mission through award winning programs that adapt to the needs, aspirations, and vision of our community while delivering a strong value proposition for the country.

HHF’s mission and programs have been recognized by The White House, US Congress, Fortune 500 Companies, US Army, other nonprofits, and even the Government of Mexico, in five areas of focus: education, workforce development, societal impact, and leadership, with culture serving as the cornerstone of its mission.

Youth Awards

The 28-year-old Youth Awards have recognized thousands of high school students from all 50 states, Puerto Rico, and Washington, D.C., for their achievements in the classroom, community, and focus on career paths in STEM fields, entrepreneurship, media, public service, and other categories.

Gold, Silver, and Bronze recipients are selected in each category and receive a one-time innovation grant to fund their college education or support a community service effort addressing a social issue. Additionally, one national awardee is selected in each category.

Once selected, recipients are celebrated in virtual ceremonies and become part of the LOFT (Leaders On Fast Track) Network, a collective of 300,000+ students and young professionals with access to mentors, resources, networking opportunities, workshops, symposia, summits, internships, and full-time positions with Fortune 500 companies.

The Ernest F. Hollings Undergraduate Scholarship offers up to $9,500 annually for two years, alongside a paid summer internship at NOAA. This program enhances students' training in oceanic and atmospheric sciences, aiming to increase public understanding and support for environmental stewardship. Eligible students must be U.S. citizens, enrolled full-time in relevant disciplines, and maintain a minimum GPA of 3.0. The experience fosters valuable skills and networks, with 100% of alumni recommending the scholarship.

The Community Connect Grants Program provides financial assistance to eligible applicants aiming to deliver broadband services in rural areas where access is limited. This initiative fosters economic growth and enhances educational, healthcare, and public safety benefits, improving the quality of life in underserved communities. By supporting projects that create better market opportunities and promote equitable access, the program plays a vital role in advancing rural development and addressing environmental justice.

The Social Impact Fund - Nationwide Grant supports innovative solutions addressing health care access, food security, and economic empowerment. Funded by the American Heart Association, this grant prioritizes community-led projects from organizations with under $10M in revenue. Eligible entities include both for-profit and nonprofit organizations based in the U.S. and Puerto Rico. Grants can provide up to $250,000 to initiatives that demonstrate measurable impact, fostering sustainable change in health and wellness.