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Best Financial Assistance Grants in Puerto Rico

Find the perfect Financial Assistance Grants in Puerto Rico on Instrumentl. 9,000+ Financial Assistance Grants in Puerto Rico in the United States.

9,000+

Available grants

$2.55B

Total funding

$5K

Median grant

9,000+ grants
$2.55B total
$5K median

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8,931 Results based on applied filters

Entergy Charitable Foundation Grant

Entergy Charitable Foundation
Corporate
United States
Unspecified amount
The Entergy Charitable Foundation Grant focuses on supporting initiatives that foster thriving communities through education, poverty solutions, and environmental programs. The foundation prioritizes funding for 501(c)(3) organizations and similar entities. Key areas include education development, innovative poverty solutions, and environmental restoration efforts, such as coastal wetland preservation. Organizations are encouraged to apply at least three months before funding is needed, ensuring timely support for impactful community projects.
Literacy Equitable & Affordable Housing Real Estate & Housing +10 more

Thornton S., Jr. and Katrina D. Glide Foundation Grant

T.S. & K.D. Glide Foundation
Private
United States
Up to US $50,000
The Thornton S. Glide, Jr. and Katrina D. Glide Foundation provides grants to qualified 501(c)(3) organizations in California that focus on animal protection, land conservancy, agriculture, and civic endeavors. Established in 1995, the foundation prioritizes grants for specific capital acquisitions and does not support operational costs or direct aid to individuals. Emphasizing local impact, California-based organizations are favored over out-of-state counterparts.
Animal Welfare - General Agriculture Land / Habitat Conservation +7 more

F26AS00030 Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $14,162,000
The Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program, initiated in FY 2001, aims to foster collaboration between State and Federal entities in conserving listed species. This program provides funding for acquiring critical land parcels to support U.S. Fish and Wildlife Service-approved recovery plans. By securing habitats at risk from development, the initiative directly addresses the primary threat to endangered species, ensuring effective and immediate conservation actions.
Wildlife Management Land / Habitat Conservation Wildlife Health

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) (357602)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) aim to support clinical trials that can be completed within a limited timeframe. This funding opportunity encourages a variety of exploratory studies that align with the NIAMS mission, focusing on interventions such as drugs, biologics, devices, and various therapies. Applications are due by 5:00 PM local time of the applicant organization.
Musculoskeletal Diseases Neurological Diseases & Disorders Skin Diseases & Dermatology +1 more

Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) (357604)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $475,000
This funding opportunity encourages applications for clinical observational studies focused on musculoskeletal, rheumatic, and skin diseases. It aims to gather essential data for designing future clinical studies, enhancing understanding of disease symptoms, progression, and patient outcomes. Observational studies supported by this initiative will contribute to the development of objective biomarkers and effective outcome measures. Applicants are invited to address key challenges in clinical project design, ensuring a robust foundation for subsequent clinical trials.
Musculoskeletal Diseases Neurological Diseases & Disorders Skin Diseases & Dermatology +1 more

NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) (357995)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement invites applications for multi-center observational studies targeting high-risk diseases relevant to NIDDK's mission. The program encourages hypothesis-driven research involving multiple clinical centers. Key deadlines for application submissions are set for February, June, and October of 2025 and 2026. It is advised to consult with NIDDK staff prior to application submission to ensure alignment with grant expectations.
Diabetes Kidney Diseases Digestive System Health & Diseases

Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) (358116)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Limited Competition Small Grant Program for NIDDK K01/K08/K23/K25 recipients offers funding opportunities for pilot studies and feasibility research. This program aims to support researchers transitioning to independent investigator roles by providing resources for small projects that can yield preliminary data for future R01 applications. Key deadlines for applications range from February 2025 through January 2028, with specific dates for standard, renewal, and AIDS-related applications.
Diabetes Kidney Diseases Digestive System Health & Diseases

The Alice M. Ditson Fund: Organizational Support - Spring Deadline

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund provides organizational support for professional performing ensembles and institutions committed to advancing the work of younger and relatively unknown living American composers. Grants are available for general operating or project support, emphasizing contemporary American classical concert music. Eligibility includes organizations without non-profit status if sponsored by a 501(c)(3) entity, while projects featuring American music are prioritized. This funding opportunity encourages innovative performances and fosters greater recognition of emerging talents in the classical music sphere.
Classical Music Opera Dance

AISES Indian Motorcycle Academic Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Canada +5 more
US $5,000
The AISES Indian Motorcycle Academic Scholarship offers $5,000 annually to support Native students pursuing degrees in STEM fields. Sponsored by the American Indian Science and Engineering Society, this scholarship aims to empower Indigenous students and enhance diversity in STEM. Eligible applicants must be current AISES members, full-time students, and enrolled citizens or descendants of recognized Native tribes. This scholarship not only provides financial assistance but also fosters community and innovation within the STEM landscape.
STEM / STEAM Education Minority Services Native American Services +4 more

The Affirm Cares Employee Foundation Grant

Affirm Cares
Private
American Samoa, Guam +4 more
Unspecified amount
The Affirm Cares Employee Foundation Grant, established by Affirm, aims to support non-profit organizations making a significant impact in financial literacy, community enrichment, and technology education. Grants range from $1,000 to $10,000, focusing on sustainable initiatives that empower communities and alleviate housing insecurity. Eligible applicants must be 501(c)(3) designated non-profits operating within the U.S. The foundation prioritizes measurable outcomes in its funding efforts, fostering civic engagement and vibrant communities.
Homelessness Services Civic Engagement & Education Financial Literacy +5 more

NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed) (357168)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $350,000
The NIDA Research Education Program (R25) supports educational activities that enhance training in biomedical, behavioral, and clinical research. Aimed at clinicians and clinical researchers, this program focuses on increasing knowledge about substance use and related disorders. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline. This initiative is crucial for developing a skilled workforce to address the nation's research needs.
Addiction & Substance Use Disorders Medical Education & Professional Training Drug Use Disorder

Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Research Resource (U24) (Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAAA Integrative Neuroscience Initiative on Alcoholism (INIA) aims to renew support for two research consortia focusing on the biological mechanisms of excessive alcohol consumption and Alcohol Use Disorder (AUD). By utilizing advanced technologies and fostering collaboration across multiple sites, this initiative seeks to standardize neurofunctional measures and enhance reproducibility in findings. Investigators are encouraged to prepare for future applications to this NOFO, which will utilize the U24 activity code.
Neuroscience Alcoholism

Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) (358937)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,000,000
This NOFO invites applications for innovative research aimed at developing and implementing interventions to prevent and treat substance use disorders (SUDs) and overdose. It encourages studies that can rapidly advance candidate solutions towards regulatory approval or clinical use, while also addressing co-morbid SUDs. The initiative supports a wide range of research including basic, clinical, translational, and implementation strategies to tackle drug misuse and related health issues, such as HIV/AIDS.
Pharmacology Addiction & Substance Use Disorders Drug Use Disorder

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative's Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting vital pain research. This initiative fosters interdisciplinary partnerships and enhances the research environment for health trainees at eligible institutions. Key application deadlines include November 19, 2024, for standard submissions, with later dates for AIDS-related applications. Engaging students in these projects is a priority to advance pain research effectively.
Chronic / Acute Pain Drug Use Disorder Anesthesia and Pain Medicine

Rapid Response Opioid And Pain Management ECHO Funding Opportunity

Association of State and Territorial Health Officials (ASTHO)
Association/Society
American Samoa, Guam +4 more
Up to US $140,000
The Rapid Response Opioid and Pain Management ECHO Funding Opportunity by the Association of State and Territorial Health Officials (ASTHO) aims to enhance clinician training in effective pain management strategies. This initiative focuses on non-opioid treatments, substance use screening, and risk reduction counseling, promoting compassionate care while addressing public health challenges and ensuring continuity for patients affected by prescription disruptions. The program seeks to improve overall health outcomes and reduce risks associated with opioid use.
Drug Use Disorder Chronic / Acute Pain

Cancer Screenings in Maine RFP

Maine Cancer Foundation
Private
United States
Up to US $80,000
The Maine Cancer Foundation is seeking proposals for cancer screening initiatives aimed at early detection and prevention. This RFP focuses on screenings for breast, cervical, colorectal, lung, prostate, and skin cancers. Proposals should align with evidence-based practices endorsed by the CDC and U.S. Preventive Services Task Force. Interested applicants are encouraged to consult with MCF prior to submission to discuss project concepts and receive feedback on draft applications.
Cancer / Oncology Preventative Healthcare Breast Cancer +5 more

NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional) (351679)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The NIDA Mentored Clinical Scientist Development Program Award aims to foster research independence in clinician scientists by providing intensive supervised research training and career development in the field of substance use and substance use disorder. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submission for this essential funding opportunity.
Addiction & Substance Use Disorders Medical Education & Professional Training Drug Use Disorder

National Child Traumatic Stress Initiative - Community Treatment and Service Centers

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Up to US $40,200,000
The National Child Traumatic Stress Initiative aims to enhance access to trauma-focused treatment and services for children and families affected by traumatic events. Funded by the US HHS through SAMHSA, this initiative seeks to support domestic public and private nonprofit entities in delivering effective interventions. The program emphasizes the importance of addressing the unique needs of children and adolescents, ensuring they receive the support necessary to recover and thrive.
Youth Services Family Services Crisis Intervention +1 more

Healthy American Forests Initiative

National Fish and Wildlife Foundation (NFWF)
Private
Puerto Rico, United States +1 more
US $250,000 - US $2,000,000
The Healthy American Forests Initiative, led by the National Fish and Wildlife Foundation (NFWF), aims to enhance forest health and resilience through targeted funding. This initiative anticipates awarding 10-15 grants ranging from $250,000 to $2 million, supporting projects up to 2 years in duration. A 20% non-federal match is required, and interested applicants are encouraged to collaborate with NFWF and Native Americans in Philanthropy for potential match funding.
Environmental Conservation Water Resource Management

NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed) (357511)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.
Science Biology Medical Education & Professional Training +3 more

Unity for Humanity Grant

Unity Technologies
Corporate
Afghanistan, Algeria +83 more
Up to US $500,000
The Unity for Humanity Grant invites innovative creators to submit impact-driven projects that utilize real-time 3D technology. This annual grant provides funding, technical support, and marketing resources to help bring visionary ideas to life. Projects must align with UN Sustainable Development Goals and demonstrate measurable impact. Eligible submissions include prototypes across various genres, fostering a more inclusive and sustainable world. Join us in empowering changemakers to make a positive global difference.
Human & Social Services Environment Health & Medicine +11 more

Modernizing Violent Death and Suicide Surveillance Using the National Violent Death Reporting System (NVDRS)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $966,085
The National Violent Death Reporting System (NVDRS) is a crucial surveillance initiative by the CDC aimed at understanding violent deaths and suicides. This funding opportunity supports state and local entities in modernizing NVDRS, enhancing data collection and reporting processes. Key activities include timely data updates, modernization assessments, and pilot projects for improved data systems. The goal is to create a sustainable national surveillance system that provides reliable data to inform public health actions and enhance violence and suicide prevention efforts.
Computer Science & Engineering Suicide Prevention Violence Prevention

Drug-Free Communities (DFC) Support Program – Competing Continuation (Year 6)

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Up to US $125,000
The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.
Addiction & Substance Use Disorders Drug Use Disorder Community / Public Safety

Drug-Free Communities (DFC) Support Program – NEW (Year 1) (363353)

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Up to US $125,000
The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.
Addiction & Substance Use Disorders Drug Use Disorder Community / Public Safety

WKKF Grant

WK Kellogg Foundation
Private
Haiti, Mexico +1 more
Unspecified amount
The WKKF Grant, offered by the W.K. Kellogg Foundation, is dedicated to fostering a future where every child and family thrives. With a focus on nurturing early education, accessible healthcare, and equitable food systems, this grant supports initiatives that empower communities across the U.S. and parts of Mexico and Haiti. Organizations meeting IRS regulations and being legal entities, particularly 501(c)(3) nonprofits, are encouraged to apply for funding to create lasting impacts in their communities.
Maternal And Perinatal Health Dental Health Workforce Preparation & Job Readiness +11 more

Howard Brown Rickard Scholarship

National Federation Of The Blind Inc
Private
District of Columbia, Puerto Rico +1 more
US $10,000

About Us

Who We Are

The National Federation of the Blind is the oldest and largest nationwide organization of blind Americans. Founded in 1940 and currently headquartered in Baltimore, the NFB consists of affiliates, chapters, and divisions in all fifty states, Washington, DC, and Puerto Rico.

What We Do

Through our network of blind members, we coordinate many programs, services, and resources to defend the rights of blind Americans, provide information and support to blind children and adults, and build a community that creates a future full of opportunities.

What We Believe

We are the only organization that believes in the full capacity of blind people and has the power to transform our dreams into reality. We believe in blind people because we are blind people—from our democratically elected leaders to our diverse nationwide membership.

Scholarship Program

Thanks to our generous partners, there are thirty $10,000 merit-based scholarships currently available. All scholarships are awarded on the basis of academic excellence, community service, and leadership. The finalists are announced every spring. They then attend our national convention in July when the winners of each individual scholarship are selected. 

Howard Brown Rickard Scholarship

The Howard Brown Rickard Scholarship, first granted in 1965, is awarded to post-secondary full time students studying law, medicine, engineering, architecture, or the natural sciences.

Education - Higher Education Vision Impairment Care & Services College Success / Persistence +5 more

Financial Assistance Grants in Puerto Rico Highlights

Looking for financial assistance grants in Puerto Rico?


Read more about each grant below or start your 14-day free trial to see all financial assistance grants in Puerto Rico recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Financial Assistance Grants in Puerto Rico

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

800+ Financial Assistance Grants in Puerto Rico grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

500+ Financial Assistance Grants in Puerto Rico over $25K in average grant size

400+ Financial Assistance Grants in Puerto Rico over $50K in average grant size

16 Financial Assistance Grants in Puerto Rico supporting general operating expenses

500+ Financial Assistance Grants in Puerto Rico supporting programs / projects

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Financial Assistance grants in Puerto Rico?

Most grants are due in the first quarter.

Q1
31.5%
Q2
23.7%
Q3
19.8%
Q4
25.0%

Typical Funding Amounts

What's the typical grant amount funded for Financial Assistance Grants in Puerto Rico?

Grants are most commonly $318,750.

$375 $375 Min.
$318,750 $318.8 K Median
$1,385,019 $1.4 M Average
$80,000,000 $80 M Max.

Average Grant Size

What's the typical amount funded for Puerto Rico?

Grants are most commonly $104,638.

$104,638

Total Number of Grants

What's the total number of grants in Financial Assistance Grants in Puerto Rico year over year?

In 2024, funders in Puerto Rico awarded a total of 1,758 grants.

2022 1,942

2023 1,805

2024 1,758

Top Grant Focus Areas

Among all the Financial Assistance Grants in Puerto Rico given out in Puerto Rico, the most popular focus areas that receive funding are Education, Human Services, and Human Service Organizations.

1. Education

2. Human Services

3. Human Service Organizations

Funding Over Time

How is funding for Financial Assistance Grants in Puerto Rico changing over time?

Funding has increased by 15.38%.

2022 $135,836,997

2023 $159,254,276
17.24%

2024 $183,744,801
15.38%

Puerto Rico Counties That Receive the Most Funding

How does grant funding vary by county?

San Juan County, Dorado County, and Loiza County receive the most funding.

County Total Grant Funding in 2024
San Juan County $85,833,046
Dorado County $27,296,199
Loiza County $11,736,039
Bayamon County $11,338,985
Vega Alta County $9,404,211