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Best Financial Assistance Grants in Puerto Rico

Find the perfect Financial Assistance Grants in Puerto Rico on Instrumentl. 9,000+ Financial Assistance Grants in Puerto Rico in the United States.

9,000+

Available grants

$2.55B

Total funding

$5K

Median grant

9,000+ grants
$2.55B total
$5K median

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8,770 Results based on applied filters

Encompass Health Therapy Grant

Encompass Health Corporation
Corporate
Puerto Rico, United States
Up to US $75,000
The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.
Medical Rehabilitation Home Health Care Health Care Access & Delivery +3 more

Postdoctoral Grant Program

University of Wisconsin - Madison
State/Local Government
United States, Wisconsin
Up to US $20,000
The Postdoctoral Grant Program at the University of Wisconsin School of Medicine and Public Health aims to support the growth and professional development of postdoctoral trainees, fellows, and associates. With funding up to $20,000 for one year, recipients can engage in independent research projects, attend workshops, or cover open-access publication fees. This initiative enhances research capacity and promotes health equity in Wisconsin, addressing critical health challenges while fostering career advancement in the medical field.
Cancer / Oncology Infectious & Parasitic Diseases Children’s Health & Pediatrics +6 more

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity from the US Department of Health and Human Services, specifically the National Institutes of Health, aims to examine the effectiveness of family navigation models that divert non-urgent mental health concerns from emergency departments. The initiative seeks to enhance mental health service engagement, provide necessary resources, and support families in overcoming barriers to help-seeking. Key deadlines for applications range from February 2025 to October 2027.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

AISES Indigenous Peoples Education Fund (IPEF) Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Canada +5 more
US $5,000
The AISES Indigenous Peoples Education Fund (IPEF) Scholarship offers $5,000 to support Indigenous students pursuing degrees in STEM fields. This scholarship is available to current AISES members who are full-time students and enrolled citizens or descendants of recognized Native American tribes. AISES aims to empower these students, fostering diversity in STEM while recognizing the importance of education as a tool for personal growth and community development.
STEM / STEAM Education Diversity, Equity & Inclusion Academic Scholarship Programs +3 more

Coastal Resilience Program RFP

National Sea Grant Law Center
Federal Government
Alabama, American Samoa +31 more
US $75,000
The National Sea Grant Law Center is inviting proposals for the Coastal Resilience Program to research laws and policies addressing coastal resilience challenges such as sea level rise and flooding. With a funding cap of $150,000 over two years, this initiative aims to assess the effectiveness of existing policies and promote informed decision-making in coastal management. Up to two projects will be selected for funding, supporting innovative solutions to enhance community resilience against environmental threats.
Marine / Ocean Conservation Environmental Policy Climate Change Resilience & Equity

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

Solid Waste Management Grant Program (364018)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.
Freshwater Conservation Environmental Contamination & Pollution Environmental Health +1 more

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Comprehensive Suicide Prevention Program for States (363329)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $650,000 - US $1,200,000
The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.
Suicide Prevention

HIV Care Grant Program - Part B States/Territories Formula and AIDS Drug Assistance Program Formula and AIDS Drug Assistance Program Supplemental Awards: Pacific Islands Jurisdictions

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The HIV Care Grant Program aims to enhance access to comprehensive, high-quality HIV care and treatment for low-income individuals in Pacific Island territories. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative supports states and territories in developing effective systems of care, ensuring that those affected by HIV receive the necessary treatment and support to improve health outcomes.
HIV / AIDS

WaterSMART Enhancing Water Resources Projects

US Department of the Interior: Bureau of Reclamation (USBR)
Federal Government
Alaska, American Samoa +22 more
US $50,000 - US $3,000,000
The WaterSMART Enhancing Water Resources Projects program invites eligible entities to secure funding for initiatives that enhance water resource management across various sectors, including conservation, infrastructure improvement, and watershed restoration. Priority is given to projects that collaboratively address community needs and yield significant environmental benefits. This funding opportunity aligns with federal priorities aimed at optimizing resource use and improving grant oversight, as outlined in recent executive orders.
Water Resource Management

Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement aims to enhance the effectiveness of HIV prevention and care planning for RWHAP Parts A and B recipients. Through the provision of training, tools, and technical assistance, this initiative seeks to optimize resource allocation and strengthen the overall system of HIV care and treatment, ultimately improving health outcomes for those affected by HIV.
HIV / AIDS

O'Reilly Automotive Foundation Grant

O'Reilly Automotive Foundation Inc
Private
United States
Unspecified amount
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
Economic Services & Development Homelessness Services Food Access & Hunger +12 more

Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $212,004 - US $2,725,311
This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.
HIV / AIDS

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

John H. Prescott Marine Mammal Rescue Assistance Grant (363929)

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.
Wildlife Management Marine / Ocean Conservation Environmental Health

Direct-to-Consumer Distribution of HIV and other STI Self-Tests

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance a web-based ordering portal for distributing 1.5 million HIV and STI self-tests to high-burden communities. By optimizing access to these self-tests, the initiative seeks to raise awareness, prevent new infections, and improve the health outcomes of users, thereby contributing to better overall public health and wellbeing.
HIV / AIDS

Accelerating Research and Development of Next Generation Malaria Vaccines Against Malaria – A Model for Mosquito-Borne Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.
Malaria Tropical Diseases

Karen Colina Wilson Foundation Grant

Karen Colina Wilson Foundation
Private
United States
US $500 - US $10,000
The Karen Colina Wilson Foundation Grant supports programs for children, youth, and women, enhancing their health and well-being through education, art, literature, and music. Established in 2006, the foundation aims to make a positive difference in their lives, particularly in Southern and Western Wayne County, Michigan. Grants typically range from $500 to $10,000, often as matching funds, fostering broader fundraising efforts by local nonprofit organizations.
Education Artist Training & Development Children’s Mental Health +13 more

Frankenthaler Climate Initiative- Implementation Grants

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $100,000
The Frankenthaler Climate Initiative offers implementation grants aimed at enhancing energy efficiency in visual arts museums, addressing climate change through innovative projects. With deadlines extended for those affected by the LA Fires, eligible institutions can apply for funding ranging from $50,000 to $100,000. This initiative supports museums of all sizes, helping them reduce emissions and operational costs while promoting sustainable practices in the arts sector.
Climate Change Resilience & Equity Renewable/Sustainable Energy Museums & Cultural Institutions +2 more

Dissertation Research Grants

Russell Sage Foundation
Private
American Samoa, Guam +4 more
Up to US $15,000
The Russell Sage Foundation offers Dissertation Research Grants to support innovative research addressing key social science questions. Focus areas include behavioral science, immigration, and economic inequality, particularly benefiting underrepresented doctoral students. Grants of up to $15,000 are available for projects that demonstrate rigorous methods and relevance to U.S. social conditions. The foundation prioritizes diverse applicants and those lacking funding resources to ensure impactful research outcomes.
Social Justice / Human Rights Economic Rights, Justice, & Mobility Workers’ Rights +3 more

Frankenthaler Climate Initiative: Scoping Grants

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $25,000
The Frankenthaler Climate Initiative provides funding for energy efficiency projects in visual arts museums, addressing climate change through innovative cultural leadership. Grants up to $25,000 support institutions in evaluating energy mitigation opportunities, enhancing efficiency, and reducing emissions. Eligible applicants include museums and visual arts schools across the U.S. The initiative encourages sustainable practices while assisting organizations in understanding their energy needs and planning for effective interventions within a project timeline of 18 months.
Climate Change Resilience & Equity Renewable/Sustainable Energy Museums & Cultural Institutions +2 more

Semnani Family Foundation Grants

Semnani Family Foundation
Private
Afghanistan, Bosnia and Herzegovina +20 more
Unspecified amount
The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.
Homelessness Services Food Access & Hunger Diseases & Conditions +14 more

Innovative Research to Improve Native Hawaiian and Pacific Islander (NHPI) Health Outcomes (R34 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Minority Health and Health Disparities (NIMHD) is offering funding for innovative research aimed at improving health outcomes for Native Hawaiian and Pacific Islander populations. This grant will support preparatory and pilot activities that focus on understanding health disparities, testing interventions for chronic diseases, and promoting health behavior changes in collaboration with community partners. Projects should address critical health issues such as cancer, diabetes, and maternal health.
Health & Medicine Indigenous Health Systems Native American Services +2 more

Genesis Mission Graduate Fellowship Pilot

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $12,000,000 - US $25,000,000
The Genesis Mission Graduate Fellowship Pilot aims to empower American scientists and engineers in the super intelligence (SI) revolution by inviting applications from U.S. higher education institutions. This initiative focuses on developing innovative doctoral training programs integrating SI with other scientific disciplines. Participants will gain valuable research experience through collaborations with DOE National Laboratories and industry, preparing them as the next generation of skilled Ph.D. scientists and engineers to tackle pressing national science and technology challenges.
Education - Higher Education Workforce Preparation & Job Readiness Emerging Technology Development +2 more

Hearst Foundation: Social Service Grant

William Randolph Hearst Foundation
Private
United States
More than US $100,000
The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.
Sustainability Food Access & Hunger Family Services +10 more

National Breastfeeding Support, Implementation, and Hospital Quality Improvement Initiative

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Breastfeeding Support Initiative aims to enhance maternity care quality by engaging diverse partners and providing training to healthcare organizations. It focuses on implementing evidence-based practices to support breastfeeding, ensuring safe and effective maternity care in hospitals across the U.S. and territories. By fostering collaboration and utilizing data for quality improvement, the initiative seeks to create a sustainable impact on maternal and infant health.
Women's Health Maternal And Perinatal Health Health Care Access & Delivery

Financial Assistance Grants in Puerto Rico Highlights

Looking for financial assistance grants in Puerto Rico?


Read more about each grant below or start your 14-day free trial to see all financial assistance grants in Puerto Rico recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Financial Assistance Grants in Puerto Rico

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

800+ Financial Assistance Grants in Puerto Rico grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

500+ Financial Assistance Grants in Puerto Rico over $25K in average grant size

400+ Financial Assistance Grants in Puerto Rico over $50K in average grant size

16 Financial Assistance Grants in Puerto Rico supporting general operating expenses

500+ Financial Assistance Grants in Puerto Rico supporting programs / projects

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Financial Assistance grants in Puerto Rico?

Most grants are due in the first quarter.

Q1
31.5%
Q2
23.7%
Q3
19.8%
Q4
25.0%

Typical Funding Amounts

What's the typical grant amount funded for Financial Assistance Grants in Puerto Rico?

Grants are most commonly $318,750.

$375 $375 Min.
$318,750 $318.8 K Median
$1,385,019 $1.4 M Average
$80,000,000 $80 M Max.

Average Grant Size

What's the typical amount funded for Puerto Rico?

Grants are most commonly $104,638.

$104,638

Total Number of Grants

What's the total number of grants in Financial Assistance Grants in Puerto Rico year over year?

In 2024, funders in Puerto Rico awarded a total of 1,758 grants.

2022 1,942

2023 1,805

2024 1,758

Top Grant Focus Areas

Among all the Financial Assistance Grants in Puerto Rico given out in Puerto Rico, the most popular focus areas that receive funding are Education, Human Services, and Human Service Organizations.

1. Education

2. Human Services

3. Human Service Organizations

Funding Over Time

How is funding for Financial Assistance Grants in Puerto Rico changing over time?

Funding has increased by 15.38%.

2022 $135,836,997

2023 $159,254,276
17.24%

2024 $183,744,801
15.38%

Puerto Rico Counties That Receive the Most Funding

How does grant funding vary by county?

San Juan County, Dorado County, and Loiza County receive the most funding.

County Total Grant Funding in 2024
San Juan County $85,833,046
Dorado County $27,296,199
Loiza County $11,736,039
Bayamon County $11,338,985
Vega Alta County $9,404,211