Best Operating Grants for Nonprofits in Puerto Rico

The ROSS Rapid Response Program (RRP) by the U.S. Department of Housing and Urban Development (HUD) provides expedited funding to assist communities in addressing urgent social needs. This program offers one-time cost-reimbursable grants for service coordination and direct services, especially in response to emergencies like natural disasters or public health crises. By streamlining the application process, the RRP empowers local leaders to efficiently support residents in HUD-assisted housing, promoting self-sufficiency and resilience.

This funding opportunity supports research aimed at improving health among Native American populations by developing, adapting, and testing interventions. It addresses significant health disparities and seeks culturally informed solutions. The initiative encourages research that informs intervention strategies tailored to community needs, focusing on sustainability and scalability. The program is vital for enhancing health equity and resilience in Native American communities, ultimately aiming to reduce morbidity and mortality through effective health interventions.

This funding opportunity announcement aims to enhance health interventions for Native American populations. It supports research to develop, adapt, and test culturally informed health promotion and disease prevention strategies. The initiative addresses significant health disparities faced by these communities, emphasizing sustainable and adaptable solutions. Researchers are encouraged to build on community strengths and resilience, focusing on effective dissemination and integration of interventions. The program welcomes applications targeting diverse Native American groups, including Alaska Natives and Native Hawaiians.

The Intervention Research to Improve Native American Health (R21 Clinical Trials Optional) aims to support exploratory studies focused on enhancing health outcomes within Native American populations. This initiative encourages research that addresses critical health disparities, tests new interventions, and develops culturally appropriate solutions to improve health and well-being. Applications are encouraged to include community-driven research, addressing unique sociopolitical and environmental challenges faced by these populations, ultimately aiming to reduce morbidity and mortality.

The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.

This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.

The Advanced Rehabilitation Research Training (ARRT) Program aims to enhance the research capabilities of individuals with advanced degrees, focusing on disability and rehabilitation research related to employment outcomes. Funded by the US HHS Administration for Community Living, this grant offers a 36-month project period, supporting multidisciplinary training for researchers, including those with disabilities, to contribute to high-quality research in the field.

The State Biomonitoring Cooperative Agreement aims to enhance public health laboratories' ability to conduct biomonitoring and assess human exposure to environmental chemicals. This funding opportunity emphasizes community investigations, state-level studies, and emerging chemicals not covered in the National Exposure Report. By improving laboratory capacity and fostering collaboration, the initiative seeks to identify harmful exposures and evaluate intervention effectiveness over a three-year period.

The NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional) aims to foster innovative research career development for clinically trained vision scientists. This funding opportunity encourages institutions to develop programs that prepare scholars for independent research careers, particularly in minimal risk clinical trials. Emphasis is placed on recruiting underrepresented groups in research, ensuring a diverse pool of clinician investigators engaged in vision research.

The OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) program aims to enhance the technological investigative capacity of ICAC task forces nationwide. Through this funding opportunity, the program will support the development and refinement of investigative tools and methods to combat child sexual abuse material, exploitation, and trafficking. The deadline for application submission is November 5, 2026, at 8:59 p.m. ET, emphasizing the urgency of addressing these critical issues.

The OJJDP FY 2026 Multistate Mentoring Programs aims to provide crucial mentoring services to at-risk youth, helping them avoid delinquency and victimization. This funding opportunity emphasizes the importance of one-on-one, group, and peer mentoring approaches. The program aligns with the U.S. Department of Justice's commitment to public safety and juvenile justice reform, addressing the needs of vulnerable populations and fostering positive youth development.

The OJJDP FY 2026 Juvenile Drug Treatment Court Program aims to enhance juvenile drug treatment courts (JDTCs) across the U.S. by supporting states, local courts, and Tribal governments. This initiative focuses on improving outcomes for youth dealing with substance use disorders or co-occurring mental health issues. The program underscores the commitment of the Office of Justice Programs to strengthen community safety and provide vital resources for effective intervention and support.

The BJA FY 2026 Veterans Treatment Court Program aims to enhance operations for veterans in the criminal justice system, focusing on reducing substance use, including opioids and alcohol. It integrates treatment for substance use and mental health disorders within a judicial framework, targeting high-risk veterans. This initiative not only addresses public safety concerns but also aims to provide necessary support and resources for veterans dealing with issues like PTSD and traumatic brain injury, fostering rehabilitation and recovery.

The Intervention Research to Improve Native American Health (R34) aims to support research that enhances health interventions for Native American populations. This includes studying the efficacy of health promotion and disease prevention strategies, culturally informed treatments, and addressing existing health disparities. The initiative encourages community-based solutions that are sustainable and adaptable to various Native American tribes. Key deadlines for grant applications are set for October 2025 and 2026, with additional dates for AIDS-related proposals.

The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.

The NIA Predoctoral Fellowship Award aims to enhance diversity in the translational research workforce focusing on Alzheimer's disease and related dementias. This funding opportunity supports promising predoctoral candidates from underrepresented backgrounds, fostering their research training and skills in various aspects of AD/ADRD. By encouraging interdisciplinary teamwork, the program seeks to develop a diverse workforce capable of contributing significantly to the prevention, treatment, and management of these conditions.

The Innovation in Behavioral Health (IBH) Model (the “Model”) is an eight-year, voluntary service delivery and payment model promoting integrated care in behavioral health (BH) settings. The IBH Model will test the impact of a value-based payment (VBP) model aligned across Medicaid and Medicare that supports an integrated care delivery framework in specialty BH organizations and settings for adult Medicaid, Medicare, and dually eligible beneficiaries with moderate to severe mental health conditions and/or substance use disorders (SUDs).The Centers for Medicare & Medicaid Services (CMS), through its Center for Medicare & Medicaid Innovation (Innovation Center), will select up to eight state Medicaid agencies (SMAs) to participate in the Model. Implementation will begin in January 2025 and end in December 2032. The Model will have an eight-year performance period, which will be comprised of a three-year Pre-Implementation Period along with a five-year Implementation Period. Up to $7.5 million dollars in cooperative agreement award funding will be available to each selected Recipient over the course of the eight years. 

The Bill Kane Undergraduate Scholarship, awarded by SHAPE America, provides $1,000 annually to undergraduate students majoring in school-based health education at accredited institutions in the U.S. or territories. Eligible candidates must be full-time students with a GPA of at least 3.25. Alongside the scholarship, recipients receive a complimentary one-year membership with SHAPE America, promoting professional development in health and physical education.

The Howard Fellowships, administered by the George A. and Eliza Gardner Howard Foundation, support early mid-career artists and scholars with $40,000 awards for independent projects in selected fields. This unrestricted, non-residency fellowship encourages significant creative development and public visibility through exhibitions or publications. Applicants should demonstrate a promising program of work and must currently reside in the U.S. or its territories. Ten fellowships are awarded annually, promoting artistic and intellectual advancement.

The NIDCD Mentored Career Development Award supports postdoctoral Au.D./Ph.D. audiologists in their research and career development. This grant aims to foster independence in scientific health-related research relevant to the NIDCD's mission. Key deadlines for applications span from June 2024 to May 2027, providing numerous opportunities for eligible candidates to secure funding and advance their careers in the biomedical and clinical sciences.

The NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) aims to foster the development of promising audiologists through comprehensive postdoctoral research experiences. This funding opportunity supports individuals in biomedical, behavioral, or clinical sciences, helping them become independent researchers. The deadlines for applications span from June 2024 to May 2027, ensuring ample time for preparation and submission.

The Barbara A. Cooley Master’s Scholarship, offered by SHAPE America, is a $1,000 annual award for master's level students enrolled in accredited health education programs in the U.S. Recipients can use the funds as they wish and receive a complimentary one-year student membership with SHAPE America. The scholarship aims to support future educators and enhance the quality of health education, promoting research and professional practice in the field.

The Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access program provides critical support to researchers by offering access to contract research organizations and subject matter experts. This funding opportunity aims to facilitate nonclinical therapeutic development efforts, helping investigators navigate the complexities of manufacturing and planning. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.

The NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) aims to support the career development of promising audiologists through rigorous postdoctoral research in biomedical, behavioral, or clinical sciences. This initiative encourages independent investigation in health-related research relevant to NIDCD's mission. Applications are due on various dates, with the next deadline on June 13, 2024, providing opportunities for advancing research in audiology and related fields.

The Leukemia & Lymphoma Society's Equity in Access Research Grants aim to enhance equitable access to care for blood cancer patients and survivors. This program funds research to identify effective interventions that increase participation in clinical trials among underrepresented groups. Projects can receive up to $500,000 annually for a maximum of five years, with a total budget cap of $2.5 million. The initiative seeks to address systemic barriers that hinder clinical trial enrollment and improve healthcare access.

The NIA Academic Leadership Career Award (K07) provides funding for established investigators to strengthen research capacity in aging and Alzheimer's Disease. The program supports the development of educational infrastructure, mentorship, and career development activities. Key deadlines for applications include February 12, June 12, and October 12 from 2025 to 2027. This award is specifically for research not involving independent clinical trials, allowing applicants to gain experience in trials led by others.