Best Small Grants for Nonprofits in Puerto Rico

The FY26 Autism Research Program's Idea Development Award from the US DOD aims to support groundbreaking research that improves outcomes for Autistic individuals. This award encourages innovative, high-risk projects that can lead to significant advancements in autism research. Applications must address specific areas of interest or justify the importance of the research problem. A unique Partnering Principal Investigator option allows two researchers to collaborate on a single project, enhancing the potential for impactful discoveries.

The FY26 Hearing Restoration Research Program (HRRP) Focused Research Award (FRA) aims to enhance drug discovery and therapeutic development for hearing restoration following military-related auditory injuries. The award supports preclinical and clinical studies aligned with HRRP focus areas. It features two funding levels, including a Partnering Principal Investigator option, and evaluates proposals based on research rationale, strategy, impact, and personnel. Notably, it excludes funding for clinical trials, tinnitus, and vestibular research.

The Can'd Aid: Crush It Crusade Grant empowers nonprofits, local education, and government organizations to enhance recycling efforts. With grants ranging from $3,000 to $8,000, the program supports initiatives that promote recycling at community events, engage volunteers, and foster inclusive outreach. Since 2014, over 125 organizations have benefited from this funding, driving impactful change through community engagement and environmental stewardship.

The FY26 Military Burn Research Program (MBRP) Technology/Therapeutic Development Award (TTDA) aims to translate promising preclinical findings into burn products for clinical use in challenging environments. This award supports the development of both tangible products, like medical devices, and knowledge products that enhance health outcomes. A new Mentorship Option encourages collaboration between experienced researchers and junior scientists, fostering the next generation of leaders in military burn care research.

The FY26 Military Burn Research Program (MBRP) Discovery Award aims to support groundbreaking research in combat-relevant burn care. This award encourages innovative and exploratory studies that provide new insights and foundational data for future clinical research. The focus is on novel approaches that lay the groundwork for scientific advancements and product development in burn care, ensuring robust preliminary data generation for subsequent research initiatives.

The DoW Military Burn, Patient-Centered Research Award aims to enhance the implementation of burn care research into clinical practice for military settings. The FY26 program supports clinical trials and research that directly benefit burn patients in resource-limited environments, fostering collaborations between experienced researchers and junior scholars. This initiative addresses critical gaps in combat burn care, ensuring effective interventions and guidelines are developed and utilized in operational battlespaces.

The Exploratory Grant Award aims to enhance workforce diversity in basic cancer research by supporting junior and Early Stage Investigators from underrepresented groups in the biomedical and social sciences. This initiative provides essential funding to bridge the gap for researchers completing their training, ensuring they have the resources needed to develop larger grant applications. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

The National Institutes of Health is funding a groundbreaking project to enhance our understanding of Type 1 diabetes (T1D) through multimodal AI. This initiative aims to integrate diverse datasets to explore the interactions of biological processes in T1D development. By leveraging advanced AI models, the research will uncover critical insights, identify biomarkers, and pave the way for personalized medicine approaches, ultimately improving prevention and treatment strategies for this complex disease.

This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.

The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.

Entergy’s Open Grants Program aims to enhance community well-being through funding initiatives in arts, education, social services, and community improvement. The program prioritizes support for organizations that serve diverse populations, including children and low-income communities. Eligible entities must have 501(c)(3) status or equivalent nonprofit recognition. Applications should be submitted three months in advance, allowing ample time for review. Entergy focuses on projects that foster self-sufficiency and enrich local neighborhoods.

Our Work:

The Citi Foundation commits $20 million to help nonprofit housing developers overcome financial and operational barriers to building and preserving affordable housing in the U.S.

Apply for Funding

Citi Foundation primarily provides funding through open Requests for Proposals (RFP). This model enables us to engage and support a broad range of organizations across the globe to tackle some of the most pressing social issues of our time. Each RFP launched is accompanied by detailed information on goals, selection criteria and relevant application deadlines.

Housing Affordability

Citi's Blueprint for Housing Opportunity

Recognized as the number one affordable housing lender in the U.S. by Affordable Housing Finance magazine, Citi knows increasing supply is essential to addressing housing affordability — one of the defining economic challenges of our time. That’s why we are putting our capital, community impact and expertise toward helping more Americans access housing they can truly afford.

The Auto Club Group Foundation focuses on creating a positive impact through grants that enhance traffic safety, driver education, and financial literacy across 14 U.S. states and two territories. With a mission rooted in community service, the foundation supports nonprofit organizations and government entities that align with its goals. Grants typically range from $5,000 to $15,000, addressing crucial areas such as traffic safety initiatives, financial literacy for K-12 students, and equitable access to driver education programs.

The Coordinating Agricultural Development & Innovation (CADI) initiative fosters trade growth in Eastern Europe, the South Caucasus, and Central Asia by removing barriers to U.S. agricultural exports. Funded by the USDA's Foreign Agricultural Service, CADI aims to inject over $622 million into the U.S. economy while preventing potential losses exceeding $50 billion. The awardee will conduct essential research and provide actionable recommendations to support U.S. farmers and enhance trade relationships, ensuring a prosperous agricultural sector.

The Clinical and Translational Science Award (CTSA) Program invites applications to enhance clinical and translational science through innovative partnerships and research programs. This initiative aims to accelerate the delivery of treatments to diverse populations by improving clinical research efficiency, creating national resources for public health responses, and providing training for clinical research professionals. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the full proposal deadline.

The Call for Kindness Grant, offered by Riley's Way Foundation, empowers young leaders aged 13-23 to launch impactful social projects focused on kindness and community connection. With grants up to $5,000, recipients receive essential mentorship, coaching, and community support. This initiative has already benefited over 3,500 youth nationwide, promoting values of empathy and social change. Applicants can pursue projects in diverse areas, including environmental justice, ensuring a broad impact in their communities.

The NIAID Research Education Program (R25) fosters diverse research careers by supporting educational activities for individuals from underrepresented backgrounds in biomedical sciences. This program encourages skills development, research experiences, and mentoring activities to enhance career trajectories. Key deadlines for grant applications include January 25 and May 25 from 2024 to 2026, with additional deadlines for AIDS-related applications. This initiative aligns with NIH's mission to diversify the research workforce.

This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.

The Blueprint MedTech Translator program aims to support the advancement of therapeutic and diagnostic devices for nervous and neuromuscular disorders. This initiative encourages clinical feasibility studies and the implementation of clinical prototype devices, along with safety and efficacy testing. Participants will receive funding to conduct research in their own labs, collaborate with NIH consultants, and access contract research organizations for specialized testing, ensuring a comprehensive approach to device development.

The Park Foundation Grants for Animal Welfare focus on advancing the protection and conservation of wildlife, particularly through policy and advocacy efforts for threatened species. The foundation supports innovative, solution-oriented models that foster systemic change and compassion. Key areas include organizing for endangered wildlife, indigenous management practices, and supporting sanctuaries for great apes. Additionally, the foundation is committed to local efforts, including support for the Tompkins County SPCA, ensuring a compassionate society for all living beings.

The DARPA Tactical Technology Office (TTO) seeks innovative proposals to enhance national security through cutting-edge technology. This initiative focuses on Design/Build/Buy, Surge and Sustain, Long Range Effects, and Disruptive Innovation. By fostering rapid adaptation and sustainable force structures, TTO aims to demonstrate revolutionary systems that are not only effective but also affordable and responsive to emerging challenges.

The FY26 Defense Established Program to Stimulate Competitive Research (DEPSCoR) Capacity Building opportunity aims to enhance the capabilities of university researchers in eligible states. Managed by the DoD, this initiative focuses on increasing the number of researchers capable of conducting relevant science and engineering research. The program also seeks to strengthen institutions of higher education and improve their competitiveness for federal research funding, ultimately fostering long-term growth in financial assistance for scientific research.

The DARPA PINPOINT program seeks innovative proposals focused on the physics and nonlinear control of inertial measurement units (IMUs) for tactical and unmanned missions. The initiative aims to break the performance plateau of MEMS IMUs by exploring novel sensor architectures like electromagnetically levitated proof masses and non-linear resonators. This program emphasizes co-designing sensor packages with advanced adaptive control systems to manage complex dynamics, encouraging revolutionary advances in science and technology.

The Carolyn L. Kuckein Student Research Fellowship, awarded by Alpha Omega Alpha Honor Medical Society, supports first and second-year medical students conducting research over 2 to 12 months. With a total funding of $7,000, students can receive reimbursement for travel expenses up to $1,000 for presenting their findings at national conferences. Eligibility requires enrollment in schools with active AΩA chapters, while those taking a year off for research or holding a PhD are ineligible.

The BJS FY 2026 Consolidated National Criminal History Improvement Program is designed to enhance the quality and accessibility of criminal history records, ensuring effective background checks for both criminal and non-criminal justice purposes. With significant funding allocated to programs like NCHIP and NARIP, the initiative aims to bolster public safety by improving the accuracy of background information and supporting state and tribal updates to the FBI's National Instant Criminal Background Check System.

Navigant Credit Union 

Navigant Credit Union is the longest-operating, member-owned credit union in Rhode Island. Since its founding in 1915, Navigant Credit Union has been dedicated to providing its members with unparalleled financial products and services, while working every day to stay committed to the financial well-being of the families, businesses and communities we serve. 

Navigant Credit Union Charitable Foundation Grant

For over a century, Navigant Credit Union has been committed to making a meaningful difference in the community. In 2017, we established the Navigant Credit Union Charitable Foundation to further amplify our impact in five strategic areas:

• Education & Financial Literacy: Organizational and capital support for programs, supplies, building products, sports facilities and teams.
• Social Services: Financial support for programs and organizations for children, veterans, hunger and housing.
• Public Health, Safety & Well-Being: Support for programs addressing public safety, emergency care and eradication of disease.