Best Unrestricted Grants for Nonprofits in Puerto Rico

The Paul B. Beeson Emerging Leaders Career Development Award in Aging is designed for early-stage physicians and health professionals committed to aging research. This initiative, supported by the NIH, aims to cultivate leadership skills and advance research in geriatrics. Eligible candidates must demonstrate prior research support and leadership in their field. While applications are not currently being accepted, this NOFO encourages potential applicants to develop collaborative and impactful projects in aging research.

The Feasibility Clinical Trials of Mind and Body Interventions grant aims to support trials that examine complementary and integrative health approaches for high-priority NCCIH research topics. This opportunity seeks to gather essential data for designing future efficacy studies, focusing on aspects such as feasibility, acceptability, and recruitment strategies. The goal is to bridge gaps in scientific knowledge and enhance public health impact through rigorous clinical research. Applicants are encouraged to contact NCCIH representatives for guidance.

The Occupational Safety and Health Education and Research Centers (T42) program, funded by the CDC, focuses on enhancing occupational safety through targeted education and training. By fostering interdisciplinary research and collaboration among academic institutions, this initiative aims to equip professionals with the necessary skills to address workplace health challenges. The program seeks to diversify the workforce and improve worker safety and well-being through outreach and continued education efforts.

The NCCIH Multi-Site Feasibility Clinical Trials (R01) invites applications for clinical trials focused on mind and body interventions. This program emphasizes the need for multisite feasibility studies to gather essential data for future efficacy trials. The initiative is designed to enhance public health by addressing gaps in scientific knowledge related to the delivery, recruitment, and data collection of integrative health approaches. Deadlines for submissions range from February 2025 to October 2026.

The IDeA Networks of Biomedical Research Excellence (INBRE) program aims to enhance biomedical research capacity in underfunded states by fostering collaborations among research institutions. By supporting faculty research, mentoring, and student involvement, INBREs create pathways for undergraduate students to enter biomedical careers. This initiative not only promotes institutional partnerships but also strengthens research infrastructure, ultimately contributing to a more robust scientific community in IDeA states.

The NIH Collaborative International Research Project aims to foster international research collaborations that align with the NIH mission. This grant encourages applications that incorporate at least one international subproject, offering oversight and tracking for NIH-funded international initiatives. Projects should leverage unique resources or populations abroad, contributing to advancements in health sciences relevant to NIH's objectives. This initiative underscores the importance of global partnerships in enhancing research capabilities and outcomes in the United States.

The NIDCR Small Grant Program for New Investigators (R03) supports early-stage scientists in dental and craniofacial research. It funds pilot studies and developmental projects aimed at generating preliminary data for future Research Project Grant (R01) applications. Key deadlines for applications include February 16, June 16, and October 16 from 2025 to 2027, addressing the need for timely submissions in this competitive funding landscape.

The Day-End Dough-Nation® Program by Panera Bread exemplifies community generosity through the donation of unsold bakery products to local charities. This impactful initiative supports various organizations that distribute food to those in need, including shelters, health centers, and youth programs. By partnering with thousands of non-profits nationwide, Panera Bread not only reduces food waste but also plays a crucial role in addressing hunger and promoting equality within communities.

The Illuminations Grant for Black Trans Women Visual Artists, a $10,000 annual grant, supports early-career Black trans women artists in the U.S. whose contributions to visual arts are often overlooked. Established in partnership with notable figures, this grant not only provides funding but also offers professional development resources. In its fifth year, it aims to address systemic barriers and enhance representation in the arts, with additional awards for finalists to further their artistic journeys.

The AARP Community Challenge Grant: Capacity-Building Microgrant offers $2,500 to support projects that enhance community livability for residents aged 50 and older. Initiated in 2017, it has funded over 1,700 projects nationwide, focusing on immediate improvements and long-term progress. Eligible organizations include nonprofits and government entities, aiming to implement innovative programs in areas like disaster preparedness, walkability, and home modifications. This initiative fosters inclusive communities and empowers older adults.

The NCAA Walter Byers Graduate Scholarship is awarded annually to one male and one female student-athlete, recognizing outstanding academic achievement and potential for success in graduate study. Each scholarship provides $24,000 for one academic year, with the possibility of renewal. Candidates must have a minimum GPA of 3.500, compete in NCAA athletics, and demonstrate strong character and leadership. The scholarship aims to support future leaders in their chosen fields, fostering excellence in academics and community engagement.

The Live Your Dream Awards, sponsored by Soroptimist International of the Americas, empower women by providing vital monetary assistance for their education and training. Each year, over $3 million is awarded to more than 2,300 women who are the primary financial support for their families. This initiative supports those overcoming significant challenges like poverty and domestic violence, ensuring they have the resources to achieve their dreams and live fulfilling lives.

The Ashland County Wildlife Conservation League David McClure Memorial Scholarship supports graduating seniors from Ashland County high schools and alternative education programs pursuing a degree in wildlife-related fields. Applicants must maintain a GPA of 3.0 or higher and be accepted into accredited colleges or vocational programs. This scholarship fosters educational growth while promoting conservation efforts, reflecting the commitment of the Ashland County Community Foundation to enhance community development and support future leaders in wildlife conservation.

The Bear Paw Resort Scholarship, offered by the Community Foundation for the Fox Valley Region, supports graduating seniors from White Lake High School who plan to pursue post-secondary education. With over $2 million available for scholarships in 2025, this initiative aims to empower students in their educational journeys. The scholarship is designed to assist with tuition costs, payable after the completion of the first semester, thereby encouraging academic success and community development.

The Kids’ Chance of America: Emergency Grant Program aims to provide essential support to state organizations facing unexpected challenges in funding scholarships for children of injured workers. This initiative ensures that these children can continue their education despite unforeseen financial hardships. Grants can be utilized for scholarships, room, board, and educational fees, emphasizing the importance of maintaining educational support for deserving students during the 2023-2024 academic year.

The Opportunities for Collaborative Research at the NIH Clinical Center aims to foster high-quality translational research partnerships between NIH intramural and extramural investigators. This program supports projects that bridge basic biological discoveries with clinical applications, ultimately enhancing patient-centric research. By facilitating collaborations, the program seeks to accelerate scientific advancements leading to improved health outcomes through innovative therapeutic interventions and diagnostic strategies.

The NIDCR is inviting applications for the continuation or revision of ongoing clinical trials through the UH3 Clinical Trial Required grant. This opportunity supports extensions for completing trials or longer follow-up periods, as well as revisions that are well justified. Key deadlines for submissions are set from March 2025 to January 2028, with optional Letters of Intent encouraged thirty days prior to application due dates. Ensure compliance with the outlined requirements to enhance your chances of funding.

The Critical Needs List by Community Foundation Tampa Bay addresses urgent, unforeseen needs of nonprofits that threaten their ability to serve the community. This innovative program allows nonprofits to submit requests for funding up to $250,000 for critical expenses such as emergency repairs and essential equipment replacement. With a focus on supporting local organizations, the program aims to match funding with community philanthropists, ensuring timely assistance to those in need.

The NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) grant aims to facilitate high-quality conferences that align with public health and scientific missions. Key deadlines include December 12, 2024, April 12, 2025, and August 12, 2025, among others, specifically for AIDS-related applications. This funding opportunity is provided by the US Department of Health & Human Services: National Institutes of Health (NIH).

The RPAC Fundraising Grants, offered by the National Association of Realtors, support state and local associations in organizing fundraising events aimed at boosting RPAC contributions. These grants require a fundraising goal three times the amount requested, ensuring tangible results. The initiative emphasizes developing detailed fundraising plans that comply with state laws regarding corporate treasury funds. This program is vital for enhancing RPAC participation and advancing property ownership advocacy.

L.L.Bean Charitable Donations supports outdoor initiatives that bring communities together. The program encourages partnerships with inspiring individuals and organizations. To apply, ensure requests are made at least eight weeks before the event. Please note that the program does not fund individuals, advertising, specific schools, or projects outside the U.S. For more information, visit their website to learn how to get involved.

The AARP Community Challenge Grant supports innovative projects that enhance community livability for people aged 50 and older. Funded by the AARP Foundation, these demonstration grants range from $10,000 to $25,000 and aim to improve pedestrian safety, expand broadband access, and reconnect divided communities. Since 2017, AARP has awarded over $20 million in grants, fostering immediate improvements and long-term progress across the United States, including Puerto Rico and the U.S. Virgin Islands.

The McKesson Foundation Grant provides funding up to $25,000 for organizations focused on improving health outcomes in underserved communities. Established in 1943, the foundation prioritizes health equity through strategic partnerships aimed at reducing cancer burdens, preparing healthcare professionals, and enhancing crisis response efforts. Eligible applicants include national and local nonprofits targeting specific regions in the U.S. and Canada. The foundation emphasizes projects that align with its mission and demonstrate significant community impact.

PetSmart Charities

We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.

Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.

Adoption Growth Grants 

Purpose

Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.

Funding Support

Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:

• Staff positions supporting in-store adoption programs and events.
• Marketing and advertising for in-store adoption programs.
• Volunteer or foster support, incentives, and recruitment related to in-store adoption events.
• Event supplies, including containment and enrichment materials.
• Shelter software and technology needs.
• Vehicle repairs or transportation to adoption events.
• Innovative in-store adoption ideas and pilot programs.
• Other costs directly associated with facilitating PetSmart adoptions and in-store events.

There are two Cohorts under this funding: Cohort 1-  Accelerating in-store adoptions; and Cohort 2: Capacity Building.

Cohort 1- Accelerating in-store Adoptions

Applicants must have completed 500 or more adoptions in a PetSmart store in the U.S. within the last 12 months.

Preference will be given to organizations that demonstrate a clear plan to expand an existing in-store adoption program or introduce new in-store adoption models that will increase adoptions.

Four Required Steps

Applicants must complete all four required steps below before submitting a grant application:

• Step 1 - Watch the kick-off video and complete the Adoption Accessibility Questionnaire
• Step 2 - Confirm eligibility and connect with your Adoptions Grant Manager: After completing the questionnaire, you will receive an email confirming your eligibility. Eligible partners will be invited to a call with their Adoptions Grant Manager to discuss the grant opportunity, expectations, and potential fit.
• Step 3 - Engage your PetSmart store partners: Discuss your intent to apply, align on goals, and gain their commitment to support the success of your in-store adoption program.
• Step 4-  Submit your application.

The Jean Dreyfus Lectureship for Undergraduate Institutions Grant provides a $25,000 award to facilitate a visit by a notable researcher in the chemical sciences to undergraduate institutions. It includes funding for summer research fellowships for two students and requires the researcher to deliver accessible lectures to the public. This initiative honors Jean Dreyfus's legacy and supports the engagement of undergraduates in scientific research and discourse.

The Gerber Foundation provides research grants focused on pediatric nutrition, aiming to enhance the health and well-being of infants and young children. Key areas of interest include applied research on nutritional issues, benefits of specific nutrients, and innovative treatment regimens. The foundation prioritizes projects that promise significant advancements in health outcomes for children from birth to age three, ensuring that grant dollars effectively address critical development challenges.

The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.