Best Unrestricted Grants for Nonprofits in Puerto Rico

The Teiger Foundation Programming Grant supports innovative visual arts projects led by curators at smaller non-profit organizations with budgets under $3.5 million. Grants of up to $150,000 are available for three years, funding development, realization, and documentation of exhibitions and related programs. The foundation emphasizes community engagement, racial justice, and artistic experimentation while encouraging collaboration with other cultural institutions. Note: The next Call for Proposals opens in Fall 2026.

The Teiger Foundation's Hosting Grant provides up to $75,000 for US-based curators or artistic directors to present contemporary visual art exhibitions that originated in different contexts. This grant encourages resource-sharing and collective learning, allowing institutions to expand their programming sustainably. It prioritizes projects affiliated with established non-profits, fostering community-building and positive change in the field of visual art while addressing issues of racial justice and climate crisis.

The NIH Director's Pioneer Award (DP1) encourages innovative research by funding exceptional scientists. This award is designed for groundbreaking projects that diverge from the investigator's current work and address significant scientific challenges relevant to the NIH mission. Applications are invited across all NIH-relevant fields, promoting high-risk, high-reward research that could transform our understanding of critical scientific areas.

The NIH Director's Transformative Research Award encourages innovative research that challenges conventional ideas. This award supports bold scientists and teams aiming to create groundbreaking technologies and new clinical approaches, ultimately transforming scientific paradigms. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it seeks to fund high-impact projects that have the potential to significantly advance science and technology.

The Veterans Legacy Grants Program (VLGP) offers funding up to $400,000 to eligible entities for cemetery research related to Veterans’ interred in national, State, or Tribal cemeteries. It aims to create educational materials promoting community engagement and understanding of Veterans' histories. Administered by the Department of Veterans Affairs, the program provides resources for educational institutions to enhance public knowledge and appreciation of Veterans’ contributions and legacies.

The Health Policy Research Scholars program, funded by the Robert Wood Johnson Foundation, aims to develop leadership among doctoral students from diverse, nonclinical disciplines. This four-year initiative focuses on aligning research with community health needs, emphasizing equity and collaboration across sectors. Scholars will receive $30,000 annually for up to four years, complemented by mentorship and training. The program targets second-year doctoral students who are committed to influencing health policy and fostering a Culture of Health in their communities.

Quality Improvement Grant Request for Proposals

Optimizing Maternal RSV Immunization Delivery: A Systems-Based Quality Improvement Initiative to Improve Uptake, Equity, and Newborn Outcomes

Pfizer, in collaboration with the Society for Maternal-Fetal Medicine (SMFM), is pleased to announce a competitive grant opportunity to support independent Quality Improvement (QI) initiatives focused on advancing maternal immunization, with a specific emphasis on Respiratory Syncytial Virus (RSV) vaccination during pregnancy.

This initiative builds upon insights generated from the Maternal Immunization Needs Assessment (MINA) project, a multi-stakeholder collaboration that identified persistent clinical, behavioral, and system-level gaps in the delivery and uptake of maternal vaccines.

We seek to fund projects that implement measurable, evidence-based interventions to improve real-world delivery of maternal RSV immunization across healthcare systems and care settings. Proposed initiatives should aim to optimize access, strengthen provider–patient communication training and tools, enhance care coordination, and address structural and behavioral barriers impacting vaccine uptake and equity.

Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies. Pfizer’s GMG competitive grant program involves a publicly posted Request for Proposal (RFP) that provides detail regarding a specific area of interest, sets timelines for review and approval, and uses an expert review panel (ERP) to make final grant decisions. Organizations are invited to submit an application addressing the specific gaps in clinical practice or care as outlined in the specific RFP.

For all QI grants, the applicant (and ultimately the grantee) will be solely responsible for the design, implementation, and conduct of the proposed initiative. Pfizer will have no involvement in project development, execution, or outcomes.

The Teiger Foundation's Curatorial Research and Development Grant offers support for innovative curatorial practices within the contemporary visual arts sector. Designed to address gaps in funding, this grant provides up to $50,000 for curatorial research projects, including travel and collaborative investigations. It emphasizes the importance of experimentation and creativity while aligning with values of racial justice and environmental sustainability. The next Call for Proposals will open in Fall 2026, with funding opportunities available to U.S.-based curators.

The Gerber Foundation provides research grants focused on enhancing the health and nutrition of infants and young children, particularly those aged 0-3. The foundation seeks innovative projects that address critical health issues and improve developmental outcomes. Grants support applied research, diagnostic tools, and treatment regimens that promise significant advancements in pediatric health. Eligible applicants include tax-exempt organizations, emphasizing a commitment to projects with a direct impact on children's well-being in the U.S.

PetSmart Charities

We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.

Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.

Adoption Growth Grants 

Purpose

Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.

Funding Support

Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:

• Staff positions supporting in-store adoption programs and events.
• Marketing and advertising for in-store adoption programs.
• Volunteer or foster support, incentives, and recruitment related to in-store adoption events.
• Event supplies, including containment and enrichment materials.
• Shelter software and technology needs.
• Vehicle repairs or transportation to adoption events.
• Innovative in-store adoption ideas and pilot programs.
• Other costs directly associated with facilitating PetSmart adoptions and in-store events.

There are two Cohorts under this funding: Cohort 1-  Accelerating in-store adoptions; and Cohort 2: Capacity Building.

Cohort 2: Capacity Building

Applicants must have completed at least one adoption in a PetSmart store within the last 12 months.

Preference will be given to organizations seeking to build a consistent, sustainable in-store adoption program. Applications should include a clear plan, with examples, for sustaining the program over time.

Four Required Steps

Applicants must complete all four required steps below before submitting a grant application:

• Step 1 - Watch the kick-off video and complete the Adoption Accessibility Questionnaire
• Step 2 - Confirm eligibility and connect with your Adoptions Grant Manager: After completing the questionnaire, you will receive an email confirming your eligibility. Eligible partners will be invited to a call with their Adoptions Grant Manager to discuss the grant opportunity, expectations, and potential fit.
• Step 3 - Engage your PetSmart store partners: Discuss your intent to apply, align on goals, and gain their commitment to support the success of your in-store adoption program.
• Step 4-  Submit your application.

The Microplastics Research and Resource Coordination Center aims to foster collaboration among researchers in biomedical and material sciences to understand the health impacts of micro/nanoplastics (M/NPs). This initiative will enhance research reliability by standardizing sampling, analytical practices, and data harmonization. The center will lead efforts in best practices and provide essential guidance to the M/NPs research community, ultimately advancing knowledge and methodologies in this critical area of study.

The BJA FY 2026 Daniel Anderl Judicial Security and Privacy Program aims to enhance the safety of federal judges and their families by preventing the disclosure of sensitive information. This funding opportunity supports state and local governments, including tribal entities, in implementing protective measures. The program emphasizes collaboration between federal, state, and local agencies to ensure justice is administered without fear of personal reprisal. Grants can only be used for the designated purpose of safeguarding federal judges as outlined in the statute.

The NIOSH Exploratory/Developmental Grant Program (R21) aims to enhance understanding of occupational diseases and injuries. It focuses on identifying risks, developing prevention strategies, and translating scientific discoveries into effective measures. Applicants are encouraged to describe the health burdens addressed, outline research activities, and demonstrate potential impacts on occupational safety. This initiative supports innovative concepts, model systems, and technologies that can significantly improve workplace health outcomes.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5424 - Adaptive Control Frameworks to Unlock Full-Scale BNR Potential

Grant Information

• Identify and categorize the dominant failure modes of current aeration and process control implementations under real-world operating conditions.
• Develop guidance on data and instrumentation requirements for utilities to support adaptive control, including the characterization of existing sensor infrastructure and the use of soft sensors where hard sensors are limited.
• Develop practical adaptive control frameworks and implementation guidance that utilities can deploy without dependence on proprietary black-box tools or specialized data science expertise, including hybrid approaches that augment conventional controls with data-driven models (e.g., artificial intelligence (AI)/machine learning (ML), digital twins) for variable flow and concentration conditions.
• Benchmark control performance against biological capacity indicators across multiple full-scale facilities to quantify the gap between achievable and realized biological nutrient removal (BNR) performance.

The Special Presenter Initiatives Grants, offered by the Mid Atlantic Arts Foundation in partnership with various local arts organizations, aim to support the presentation of professional performing artists at small and mid-size community venues. This initiative encourages projects that feature touring artists and includes community engagement activities, fostering meaningful interactions between artists and local audiences. The program seeks to enhance the cultural landscape of the participating jurisdictions through diverse and innovative performances.

The NIOSH Support for Conferences and Scientific Meetings (R13) program aims to fund high-quality scientific gatherings that enhance occupational safety and health research. It supports meetings that align with NIOSH's mission and priorities, encouraging the exchange of information on relevant topics. Applications should focus on advancing research in these areas, fostering collaboration among professionals. Note that training-only events are not eligible for funding under this program.

The NIOSH Support for Conferences and Scientific Meetings (U13) program aims to fund high-quality scientific gatherings that advance research in occupational safety and health. By promoting collaboration among experts, this program supports workshops and conferences aligned with NIOSH mission priorities. Federal involvement is significant, ensuring guidance and coordination throughout the award process. Applications for training-only events are not eligible, emphasizing the focus on comprehensive scientific discourse.

The Occupational Safety and Health Research (R01) grant aims to enhance understanding of workplace hazards, develop strategies to mitigate risks, and translate research into effective prevention measures. This initiative encourages applicants to address specific occupational health challenges and articulate the anticipated outcomes of their research, contributing to the reduction of work-related illnesses and injuries. By fostering innovative solutions, this grant supports the mission of NIOSH and promotes safer working environments.

The Southern SARE: Professional Development Grants support educational initiatives for agricultural professionals, enhancing outreach and training efforts directly benefiting farmers and ranchers. These grants fund diverse training activities, including workshops and farm tours, aimed at promoting sustainable agriculture through effective participatory methods. Projects are encouraged to involve multi-disciplinary partnerships and the participation of land-grant institutions, ensuring a comprehensive approach to agricultural education. Priority is given to projects with budgets under $80,000, fostering a broad array of impactful initiatives.

The Southern SARE: On-Farm Research Grant supports agricultural professionals in collaborating with farmers to conduct innovative on-farm research projects focused on sustainable agriculture. This initiative emphasizes building strong relationships between researchers and farmers while addressing agricultural production challenges. By fostering new practices in production and marketing, it aims to enhance sustainability in the agricultural sector, thereby benefiting local communities and the environment.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5416 - Innovative Approaches to Extend Lifetime and Minimize O&M for Nature-based Installations

Grant Information

• Identify and evaluate innovative design, construction, and management approaches that extend the functional lifetime of nature-based installations and reduce ongoing operations and maintenance (O&M) requirements.
• Develop practical guidance on key factors affecting nature-based solution (NbS) longevity, including hydraulic optimization, engineered media selection and replacement, plant selection, sediment management, and construction-phase best practices.
• Survey utilities and other NbS owners to document current maintenance practices, costs, and hours, and establish benchmarks to inform targets for improvement.

The Mutual Self-Help Housing Technical Assistance Grants in Puerto Rico provide essential support to organizations aiding low-income families in constructing their own homes. These grants enable recipients to offer technical guidance and supervision, facilitating community-driven housing projects. Eligible entities include government non-profits and federally recognized tribes, while funding cannot be used for direct construction labor or purchasing materials. This program fosters self-sufficiency and strengthens community ties in rural areas.

The World Trade Center Youth Research Coordinating Center aims to establish a research cohort to study the health impacts on youth exposed to the 9/11 events. This initiative, backed by the NIOSH, will focus on individuals aged 21 or younger at the time of exposure, including those in utero. The Center will integrate diverse expertise to assess long-term health and educational effects while enhancing community engagement and stakeholder communication throughout its activities.

The State Occupational Safety and Health Surveillance Program (U60) aims to enhance state-level occupational safety and health (OSH) surveillance capacity. Funded by NIOSH, this initiative supports various state programs, fostering partnerships among health departments and universities. By utilizing diverse data sources, these programs assess workplace health impacts and develop tailored interventions, ultimately ensuring better health and safety for workers across the U.S. This collaborative approach addresses critical gaps left by regulatory programs.

The TYLENOL Future Care Scholarship supports students pursuing healthcare careers, continuing a 30-year tradition of helping those dedicated to caring for others. Eligible applicants must be U.S. residents, graduate students or seniors enrolling in graduate school for the 2024-25 academic year, and provide proof of enrollment in an accredited healthcare program. Scholarships cover tuition, fees, and necessary supplies, ensuring that future healthcare professionals receive the support they need.

The Infant-Toddler Court Program's National Resource Center (NRC) focuses on enhancing child welfare practices across the United States. By collaborating with courts, social services, and families, the NRC aims to improve the safety and healthy development of young children involved with the child welfare system. This initiative not only supports families but also fosters nurturing relationships essential for child growth and well-being, making it a crucial resource for communities.

The "Opportunities for Collaborative Research with the NIH Intramural Research Program (U01 Clinical Trial Optional)" aims to foster partnerships between NIH intramural and extramural researchers. This initiative supports translational research projects that bridge basic biological discoveries and clinical applications, enhancing health outcomes. By encouraging collaborations, it seeks to accelerate the development of new therapies and prevention strategies, leveraging unique NIH resources to strengthen scientific innovation and address critical disease processes.