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Best Unrestricted Grants for Nonprofits in Puerto Rico

Find the perfect Unrestricted grants for nonprofits in Puerto Rico on Instrumentl. 9,000+ Unrestricted grants for nonprofits in Puerto Rico in the United States.

9,000+

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$2.55B

Total funding

$5K

Median grant

9,000+ grants
$2.55B total
$5K median

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Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,500,000
This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.
Drug Use Disorder Addiction & Substance Use Disorders Pharmacology +1 more

RMEF Grant Program- Hunting Heritage

Rocky Mountain Elk Foundation (RMEF)
Private
United States
Unspecified amount

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Hunting Heritage

Ensuring our hunting heritage is central to RMEF’s mission. Hunters—America’s first conservationists—remain the driving force behind wildlife conservation. RMEF funds hunting heritage and conservation education to help more people experience the outdoors, learn the skills of hunting, and carry forward the traditions that define big game country, including outdoor skills programs/events, hunter or conservation outreach, mentored hunts, and other similar activities.

Land / Habitat Conservation Sport Shooting Outdoor Recreation +2 more

Healthcare Access Initiative Grant

National Association of Free and Charitable Clinics Inc
Private
United States
US $20,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Healthcare Access Initiative

The Healthcare Access Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to expand access to essential healthcare services for uninsured and medically underserved individuals. Free and charitable clinics and pharmacies play a critical role in ensuring that patients who fall outside traditional healthcare systems can receive timely, high-quality care. However, many clinics face barriers related to staffing, care coordination, technology, and patient outreach that limit their ability to meet growing community needs. Through this initiative, NAFC will provide $20,000 grants to member clinics and pharmacies to strengthen programs that increase access to primary care, specialty services, and preventive care. Funding will support innovative and practical approaches that reduce barriers to care, improve patient engagement, and expand the capacity of clinics to serve vulnerable populations.

Patient Care & Services Health Care Access & Delivery Health Facilities & Clinics +3 more

Collections-Related Grants

Carl And Marilynn Thoma Foundation
Private
United States
Unspecified amount
The Carl & Marilynn Thoma Foundation offers Collections-Related Grants for Nonprofits, aimed at enhancing public interest in art through innovative projects. Grants support exhibitions, academic convenings, research, and catalog publication, focusing on art from the Spanish Americas, digital media, and more. The foundation prioritizes proposals from 501(c)(3) organizations in the U.S., particularly from New Mexico, Oklahoma, and Texas, fostering partnerships that advance art scholarship and cultural engagement.
Asian Art Folk Art / Traditional Art Media Arts +5 more

Center for Family Engagement Healthy Minds Fellowship

National Congress of Parents & Teachers
Corporate
United States
US $1,000
The Center for Family Engagement Healthy Minds Fellowship, organized by the National PTA, invites active PTA leaders to enhance their mental health expertise over a 12-month cohort starting January 2026. Participants will receive a $1,500 stipend and engage in developing actionable plans to improve mental health initiatives in schools. This fellowship aims to empower leaders through workshops and collaborative efforts, fostering a supportive environment for mental wellness in educational settings.
Child Welfare Services Children’s Mental Health Parenting Counseling & Education +2 more

Gamma Mu Foundation Grant

Gamma Mu Foundation
Private
United States
Up to US $15,000
The Gamma Mu Foundation, established in 1988, aims to support the LGBT community in rural and underserved areas through various grants. Initially focused on HIV/AIDS projects, it now funds scholarships and services for diverse LGBT subpopulations. With over $2 million awarded, the Foundation prioritizes initiatives that enhance community support, public education, and health programs. It emphasizes projects that build organizational capacity and provide essential services where resources are limited, ensuring ongoing support for vital health and social services.
LGBTQIA+ Services HIV / AIDS Sexuality & LGBTQIA+ Rights

Oriental Trading Co. Corporate Giving Program

Oriental Trading Company
Corporate
United States
Unspecified amount
The Oriental Trading Company Corporate Giving Program focuses on enhancing the lives of children through education, youth programming, healthcare, and human services. With a commitment to making the world a better place, they support organizations that are tax-exempt under Section 501(c)(3) or public educational institutions. Their initiatives aim to foster community partnerships and provide essential resources to youth in need, ensuring they have access to vital services and opportunities for growth.
Youth Services Children’s Health & Pediatrics Children’s Mental Health +5 more

Quadratec Cares 'Energize The Environment' Grant Program

Quadratec
Corporate
United States
US $3,500
The Quadratec Cares 'Energize The Environment' Grant Program is dedicated to supporting individuals and organizations in the U.S. focused on environmental improvement. With two grants of $3,500 awarded annually, the program encourages initiatives like trail restoration and community educational projects. This grant aims to empower passionate individuals to enhance environmental awareness and stewardship, ensuring a healthier planet for future generations.
Trail Creation & Maintenance Greening & Beautification Parks & Public Spaces +3 more

Barney Family Foundation Grant

Barney Family Foundation
Private
United States
US $5,000 - US $50,000
The Barney Family Foundation Grant focuses on improving early education and advancing medical research, particularly in cancer and Alzheimer’s. It supports organizations that demonstrate a clear plan to enhance children's life experiences and educational opportunities for those in grades K-8. Grants typically range from $5,000 to $50,000, prioritizing established entities while welcoming startups. Eligible applicants must have 501(c)(3) status, and the Foundation does not fund individual requests or political activities.
Education - Preschool / Early Learning Education - Middle School Education - Elementary School +2 more

Joseph G. Markoly Foundation Grant Support for Elder Organizations

Joseph G Markoly Foundation Inc
Private
United States
Unspecified amount

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Elder Organizations

The Markoly Foundation takes pride in supporting local organizations that provide services for elders in our community. Seniors face a number of challenges that come with aging, especially when they don’t have loved ones who are able to assist them with their needs. We provide grants for a variety of senior-related programs from Caregiver Education and Support to Emergency Meal Delivery and Transportation Services.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

Senior Services Caregiver Support / Respite Care Food Delivery & Distribution Services +1 more

Preparing for UCMR 6: Understanding Occurrence of Trifluoroacetic Acid and Emerging Ultrashort-Chain PFAS RFP

Water Research Foundation
Private
United States
Up to US $200,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5434 Preparing for UCMR 6: Understanding Occurrence of Trifluoroacetic Acid and Emerging Ultrashort-Chain PFAS

Grant Information

  • Characterize the occurrence of trifluoroacetic acid (TFA) and other ultrashort-chain organofluorine compounds included in the Sixth Unregulated Contaminant Monitoring Rule (UCMR 6) in representative U.S. drinking water systems.
  • Evaluate changes across existing full-scale treatment processes using source and finished water samples to identify treatment trains that demonstrate measurable removal or reduction of these compounds.
  • Develop a response and communication protocol to support utilities when communicating the results of the sampling and potential detection of TFA and other UCMR 6 ultrashort-chain organofluorine compounds.
Hydrology Water Resource Management Sanitation & Clean Drinking Water

Jennie Wade Scholarship Endowment

Community Foundation of Wabash County
Private
United States
Unspecified amount

About Us

Our Mission

We create lasting impact through asset development, nonprofit capacity building, and community leadership. 

Our Vision

To enrich the lives of Wabash County residents by fostering opportunity, inspiring generosity, and building a thriving connected community. 

Our Scholarships

For High School Seniors & Non Traditional Students who are beginning college more than one year after high school.

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.    

Jennie Wade Scholarship Endowment

More than one hundred years ago, Jennie Wade created a scholarship in her words “to benefit mankind.” This scholarship is made to help young men and women continue their education after high school. Wabash County residents under the age of 21 are selected from among applicants who have done as much as possible in helping themselves obtain an education and whose families are unable to provide an education.

Workforce Preparation & Job Readiness Career / College Preparation Education - Higher Education +3 more

FY25-FY26 Advanced Transportation Technology and Innovation (ATTAIN)

DOT Federal Highway Administration
Federal Government
United States
Up to US $12,000,000
The FY25-FY26 Advanced Transportation Technology and Innovation (ATTAIN) grant program aims to enhance transportation through the deployment of innovative technologies. It focuses on improving safety, mobility, and efficiency while fostering economic competitiveness. Projects funded will prioritize core infrastructure improvements and address roadway congestion, aligning with the Trump Administration's goals. The program emphasizes economic opportunities and community benefits, ensuring that selected projects contribute positively to families and communities, ultimately enhancing their quality of life.
Public Transportation & Mass Transit Systems Pedestrian & Bike-Friendly Infrastructure Automotive Safety +1 more

Quest for Healthy Communities Champions Grant

Quest Diagnostics Foundation Inc
Private
United States
US $10,000

Quest Diagnostics Foundation

Established as a 501(c)(3) nonprofit organization, the Quest Diagnostics Foundation is committed to addressing the systemic root causes of health disparities. By combining corporate resources with trusted community leadership, we fund and scale evidence-based initiatives that promote wellness, prevent chronic disease, and empower individuals.

We focus our resources on three critical, interconnected clinical and social interventions to build sustainable health improvement:

  • Strengthening the community health workforce
  • Addressing social drivers of health (SDoH)
  • Promoting the prevention, early detection, monitoring, and treatment of disease through diagnostic testing

About Quest for Healthy Communities Champions

The Quest for Healthy Communities Champion award was created to honor, uplift, and support outstanding organizations across the United States that are actively living our core purpose:

Working together to create a healthier world, one life at a time.

Whether you are expanding access to life-saving screenings, supporting maternal and family wellness, or addressing critical social drivers of health, your dedication is moving us closer to an equitable healthcare future. We want to recognize and celebrate your impact.

What we celebrate: Our core impact pillars

The Champions we look to honor are community-first organizations and coalitions tackling critical disparities head-on. We are especially excited to spotlight work that advances health, addresses social drivers of health, fosters community-clinical linkages and develops the community workforce. Examples of this work could include: 

  • Programs actively dismantling clinical barriers to ensure every individual—regardless of zip code, background, or income—has access to high-quality care
  • Innovators providing creative solutions for food security, transportation, health education, and maternal-child support networks
  • Organizations bringing critical care directly to those in need through mobile clinics, community health workers, and localized diagnostic screenings
  • Organizations finding creative ways to engage the communities they serve directly into the solutions they are delivering

The award: Selected organization champions will receive a $10,000 grant.

Health Policy & Advocacy Children’s Health & Pediatrics Maternal And Perinatal Health +3 more

Scholarships for Graduate Students: AWWA Abel Wolman Fellowship

American Water Works Association (AWWA)
Association/Society
Canada, Mexico +1 more
Up to US $30,000
The AWWA Abel Wolman Fellowship, established in 1984, supports highly qualified students conducting meaningful research in water supply through doctoral programs. Named after Dr. Abel Wolman, this prestigious award recognizes excellence and creativity in the water sector. The fellowship provides up to two years of financial support, with an initial award of $30,000 for the first year, aimed at fostering the next generation of water professionals in the U.S., Canada, and Mexico.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

AWWA Scholarship Program - Carollo Engineers Bryant L. Bench Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $10,000
The AWWA Scholarship Program, specifically the Carollo Engineers Bryant L. Bench Scholarship, offers a $10,000 award to graduate students dedicated to advancing their careers in the water consulting engineering field. Established in honor of Bryant L. Bench, this scholarship aims to support future leaders who will enhance drinking water quality through innovative engineering solutions. The American Water Works Association emphasizes the importance of investing in students to secure the future of the water industry.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

Mosaic Company Foundation Community Investment Grant

Mosaic Company Foundation
Corporate
Canada, Colorado +8 more
Unspecified amount
The Mosaic Company Foundation Community Investment Grant aims to create a lasting impact in communities by supporting initiatives in three key areas: Food, Water, and Local Community. With an annual investment of approximately $12 million, the foundation addresses food security, promotes water conservation, and enhances community sustainability. Eligible applicants must be recognized charitable organizations, primarily in North America, committed to improving quality of life through innovative solutions and partnerships.
Agriculture Food Security Freshwater Conservation +2 more

National Girls and Women in Sports (NAGWS) Legacy Award

Society Of Health And Physical Educators
Private
United States
US $1,000
The National Girls and Women in Sports (NAGWS) Legacy Award, established by SHAPE America, honors exemplary contributions to increasing opportunities for women in sports. This annual award recognizes current SHAPE America members who submit impactful proposals related to women's sports, with a monetary prize of $1000. The award will be presented at the National Convention & Exposition, with a special deadline of November 1st. Nominations can include various initiatives aimed at empowering women in sports.
After School / Summer Educational Programs Women & Girl Services Sports & Athletics +5 more

AWWA Scholarship Program - Hazen Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $10,000
The AWWA Hazen Scholarship supports graduate-level candidates dedicated to improving water quality and resources. Awarded by the American Water Works Association, this scholarship aims to empower future leaders in the water industry. Candidates must demonstrate commitment to addressing critical challenges in drinking water, water reuse, and sustainable practices. This initiative reflects AWWA's mission to invest in the next generation of water supply professionals, ensuring a sustainable future for water resources.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

WWA Scholarship Program - HDR One Water Institute Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $10,000
The HDR One Water Institute Scholarship, offered by the American Water Works Association, provides $10,000 in funding to support graduate students pursuing degrees that will lead to careers as consultants in the water industry. This initiative highlights the importance of investing in future water professionals and fostering innovative research to address pressing water challenges.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

AWWA Scholarship Program - Mueller HBCU Scholarship

American Water Works Association (AWWA)
Association/Society
North America
Unspecified amount
The AWWA Scholarship Program, specifically the Mueller HBCU Scholarship, supports undergraduate students from historically black colleges and universities pursuing careers in the water sector. Offered by the American Water Works Association (AWWA), this scholarship recognizes the vital role of future professionals in addressing water industry challenges. AWWA aims to invest in students who will contribute to sustainable water management and innovation within their communities.
Sanitation & Clean Drinking Water Water Resource Management Academic Scholarship Programs

Systemic Sclerosis with Interstitial Lung Disease Fund

Healthwell Foundation
Private
United States
Up to US $9,000
The Systemic Sclerosis with Interstitial Lung Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from systemic sclerosis. This rare autoimmune disease leads to excessive collagen production, causing serious health issues. The fund assists with prescription copays and insurance premiums to ensure patients receive necessary treatments. In 2024, HealthWell awarded over $1.2 billion in grants, supporting more than 1.1 million patients in accessing vital healthcare services.
Cardiovascular Diseases & Systems Neurological Diseases & Disorders Multiple Sclerosis +3 more

Tee It Up for the Troops Grant

Tee It Up For The Troops Inc
Private
United States
Unspecified amount
Tee It Up for the Troops Grant supports 501(c)3 organizations that aid military personnel and their families. Prioritizing employment, family support, housing, PTSD treatment, sports rehabilitation, and suicide prevention, the grant aims to enhance the lives of veterans. Organizations that do not engage in fundraising events are eligible for funding. This initiative seeks to create a positive impact within the military community through various support pillars.
Military & Veterans Services Suicide Prevention Brain Injuries +1 more

Opioid Crisis Response Program Fellowship

Equal Justice Works
Private
United States
Unspecified amount
The Opioid Crisis Response Program Fellowship, offered by Equal Justice Works, addresses the opioid epidemic by mobilizing public interest lawyers to provide vital civil legal aid to underserved communities affected by Opioid Use Disorder. This two-year fellowship enables attorney fellows to advocate for clients' rights, reduce barriers to treatment, and enhance community education about legal impacts. Through collaboration with various stakeholders, the program aims to improve health outcomes and foster systemic change in the fight against this public health crisis.
Addiction & Substance Use Disorders Drug Use Disorder Legal Services +1 more

Michael & Susan Dell Partnerships

Michael & Susan Dell Foundation
Private
Africa, India +2 more
Unspecified amount
The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.
Poverty Alleviation & Services Education - Preschool / Early Learning Education - K through 12 +4 more

Cancer-Related Behavioral Health Fund

Healthwell Foundation
Private
United States
Up to US $2,000
The Cancer-Related Behavioral Health Fund, established by the HealthWell Foundation, provides financial assistance to individuals diagnosed with cancer for behavioral health treatments. This fund covers costs associated with prescription drugs, counseling services, and transportation. Aiming to alleviate financial burdens, it ensures that underinsured patients can access necessary care without delay. In 2024, the foundation awarded over $1.2 billion, emphasizing its commitment to improving health outcomes for cancer patients across the United States.
Cancer / Oncology Crisis Intervention Health Care Access & Delivery +2 more

Unrestricted Grants for Nonprofits in Puerto Rico Highlights

Looking for unrestricted grants for nonprofits in Puerto Rico?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in Puerto Rico recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in Puerto Rico

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

800+ Unrestricted grants for nonprofits in Puerto Rico grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

500+ Unrestricted grants for nonprofits in Puerto Rico over $25K in average grant size

400+ Unrestricted grants for nonprofits in Puerto Rico over $50K in average grant size

16 Unrestricted grants for nonprofits in Puerto Rico supporting general operating expenses

500+ Unrestricted grants for nonprofits in Puerto Rico supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in Puerto Rico?

Most grants are due in the first quarter.

Q1
31.5%
Q2
23.7%
Q3
19.8%
Q4
25.0%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in Puerto Rico?

Grants are most commonly $318,750.

$375 $375 Min.
$318,750 $318.8 K Median
$1,385,019 $1.4 M Average
$80,000,000 $80 M Max.

Average Grant Size

What's the typical amount funded for Puerto Rico?

Grants are most commonly $104,638.

$104,638

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in Puerto Rico year over year?

In 2024, funders in Puerto Rico awarded a total of 1,758 grants.

2022 1,942

2023 1,805

2024 1,758

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in Puerto Rico given out in Puerto Rico, the most popular focus areas that receive funding are Education, Human Services, and Human Service Organizations.

1. Education

2. Human Services

3. Human Service Organizations

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in Puerto Rico changing over time?

Funding has increased by 15.38%.

2022 $135,836,997

2023 $159,254,276
17.24%

2024 $183,744,801
15.38%

Puerto Rico Counties That Receive the Most Funding

How does grant funding vary by county?

San Juan County, Dorado County, and Loiza County receive the most funding.

County Total Grant Funding in 2024
San Juan County $85,833,046
Dorado County $27,296,199
Loiza County $11,736,039
Bayamon County $11,338,985
Vega Alta County $9,404,211