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The Miniaturization and Automation of Tissue Chip Systems (MATChS) initiative by the NIH aims to advance biomedical research through the development of automated tissue chip platforms. This program encourages small businesses to propose innovative technologies that enhance data acquisition and analysis while minimizing manual handling. Funded projects will create efficient, miniaturized systems vital for drug development and other research applications. Collaboration with NIH staff is expected to ensure milestones and commercial pathways are effectively established.

The Dow Promise Grant empowers communities by addressing the unique barriers faced by Black youth and adults in the U.S. This program provides grants up to $10,000 for initiatives that promote social, economic, and environmental advancements. Since its inception in 2000, the Dow Promise Program has been committed to fostering equitable opportunities and positive social change, ultimately contributing to long-term community success and a brighter future for all.

The Fiscal Year 2026 National Earthquake Hazards Reduction Program aims to enhance earthquake risk mitigation through multi-state and national activities. Funded by FEMA, this program supports nonprofit organizations and educational institutions in developing initiatives that align with NEHRP goals. Priorities include seismic community development and business sector outreach, ensuring preparedness across various regions. This grant fosters collaboration among key agencies to improve resilience against earthquakes, ultimately safeguarding communities and enhancing public safety.

The NALAC Fund for the Arts offers organization grants focused on supporting Latinx artists and arts organizations in the U.S. and Puerto Rico. This funding initiative has invested over $6 million in the arts community, nurturing creativity and social change. Eligible applicants include organizations with a mission centered on Latinx arts. The program aims to enhance artistic excellence and community engagement, making it a vital resource for cultural production and social justice efforts.

The BJA FY 2025/2026 Project Safe Neighborhoods Formula Grant Program aims to enhance community safety by funding comprehensive violent crime reduction strategies across the U.S. This initiative, coordinated by U.S. Attorney’s Offices, unites law enforcement, prosecutors, and community partners to tackle issues like drug trafficking and human trafficking. Applications are due by August 27, 2026, emphasizing the DOJ's commitment to empowering communities against ongoing threats and fulfilling its core policy goals.

The Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement aims to enhance the effectiveness of HIV prevention and care planning for RWHAP Parts A and B recipients. Through the provision of training, tools, and technical assistance, this initiative seeks to optimize resource allocation and strengthen the overall system of HIV care and treatment, ultimately improving health outcomes for those affected by HIV.

The AIDS Drug Assistance Program (ADAP) Emergency Relief Funds aim to provide essential funding to states and territories. This initiative focuses on preventing, reducing, or eliminating waiting lists for ADAP services, ensuring timely access to necessary medications and support for individuals living with HIV/AIDS. This program addresses critical funding shortfalls, enhancing the healthcare infrastructure and improving health outcomes in affected communities.

The Ryan White HIV/AIDS Program Part C Capacity Development Program aims to enhance the capabilities of community-based organizations, focusing on improving health outcomes and decreasing HIV transmission. This initiative supports individuals who have not yet accessed regular HIV care, emphasizing innovative care solutions and infrastructure development to address these critical needs.

The HIV Care Grant Program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to enhance access to high-quality HIV care and treatment for low-income individuals. This initiative supports states and territories in developing comprehensive systems to address the needs of those living with HIV. By providing essential resources, the program seeks to improve health outcomes and ensure that vulnerable populations receive the necessary support and services.

The National Cancer Institute invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation of assays, emphasizing the importance of human samples. The program encourages multi-disciplinary collaboration and aims to enhance the performance and reproducibility of cancer assays across clinical laboratories. Applications are due by 5:00 PM local time during the designated deadlines each year.

The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.

The Administration for Children and Families (ACF) anticipates soliciting applications for a National Research Center for Promoting Work and Strong Families.The Center aims to improve the effectiveness of federal and state policies that promote the dignity of work, economic self-sufficiency, and build stable, married families while reducing their reliance on public assistance. The Center will support rigorous, policy-relevant research and build stronger connections between researchers and policymakers in human services programs.The Center will carry out three core activities:

Fellowship Program: Support in-residence fellows placed within ACF and other HHS offices to provide policy-relevant research expertise on work, earnings, family stability, and human services programs.

Extramural Research Grants: Administer a competitive grant program to fund timely, actionable research aligned with ACF priorities, including promoting the dignity of work, economic self-sufficiency and reduced dependence on public assistance, family formation and stability through marriage, child well-being, and program effectiveness.

Dissemination and Communication: Host in-person and virtual events and produce policy-focused materials to ensure research findings are accessible and actionable for federal, state, tribal, and local policymakers. ACF anticipates making one cooperative agreement award for a five-year project period. The recipient must be able to show, and ACF must be able to monitor, that funds appropriated were spent on activities that can be directly attributed to those required and allowed by each funding source.

The Disability Inclusion Fund Grant, managed by Borealis Philanthropy, aims to support organizations advocating for disability inclusion, rights, and justice. As a partner in philanthropy, Borealis facilitates donor collaboratives to maximize impact across various communities and movements. Organizations interested in applying for this grant are encouraged to review the detailed FAQ for further information. This initiative is a vital step towards fostering inclusivity and promoting the rights of individuals with disabilities.

The HEAL Initiative aims to develop non-addictive therapeutics for pain management through small molecules and biologics. This funding opportunity supports preclinical optimization, facilitating the transition of promising candidates to clinical trials. Important proposal deadlines span from January 2024 to January 2027, with optional Letters of Intent encouraged 30 days prior. The program emphasizes collaboration with NIH staff to ensure thorough project planning and monitoring, aiming to revolutionize pain treatment while ensuring safety and efficacy.

The Blueprint Neurotherapeutics Network (BPN) invites small businesses to apply for funding to advance small molecule drug discovery and development projects for nervous system disorders. This program supports research through disease-specific assays and partnerships with NIH-funded consultants. Key deadlines for application submissions span from February 2024 to August 2026. BPN ensures institutions retain IP rights for developed drug candidates, facilitating control over patent negotiations.

The Rauschenberg Medical Emergency Grants, administered by the New York Foundation for the Arts, provide one-time funding up to $5,000 for artists facing unexpected medical emergencies. This program aims to alleviate financial burdens caused by medical costs, ensuring that artists can receive necessary care without delay. Eligible applicants must be practicing artists in visual arts, film, or choreography, and demonstrate financial need. This initiative supports artists of color, LGBTQ+ individuals, and those outside major coastal cities.

The DoW Neurofibromatosis Research Academy – Leadership Award supports established neurofibromatosis investigators to lead a virtual research academy. Designed for early-career scholars, this award promotes mentorship and collaboration in neurofibromatosis research. The Academy Director and Deputy Director, both at the Associate Professor level, will oversee pilot research projects that engage scholars and their mentors, fostering a dynamic research environment. This initiative aims to enhance the future of neurofibromatosis research through innovative leadership and collaboration.

The NIAID Research Education Program (R25) fosters diverse research careers by supporting educational activities for individuals from underrepresented backgrounds in biomedical sciences. This program encourages skills development, research experiences, and mentoring activities to enhance career trajectories. Key deadlines for grant applications include January 25 and May 25 from 2024 to 2026, with additional deadlines for AIDS-related applications. This initiative aligns with NIH's mission to diversify the research workforce.

Charlie's Heart Foundation Annual Grant Program supports small nonprofits focusing on mental well-being for families in underserved communities. Grants between $5,000-$30,000 are available, prioritizing organizations based in North Carolina. Eligible applicants must be 501(c)(3) tax-exempt and demonstrate alignment with the Foundation's mission, organizational need, and program sustainability. The Foundation does not fund individuals, private foundations, or religious organizations, ensuring a strong focus on impactful community programs.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

The ACT on Health Equity Community Solutions Challenge Grant, backed by the Astrazeneca Foundation, aims to enhance health equity by funding community-based nonprofit programs. Since its inception in 2021, it has allocated over $2.6 million to initiatives addressing nutrition, healthcare access, and lung health for historically marginalized populations. Eligible US-based 501(c) organizations can apply, with a focus on projects serving underserved communities and improving health outcomes through targeted support.

The Child Protection Compact Annual Program Statement invites proposals aimed at combating child trafficking through collaborative efforts between the United States and other countries. This initiative focuses on enhancing the capacity to prosecute traffickers, providing care for victims, and implementing preventive measures. Organizations interested in applying must align with the objectives of the CPC to ensure comprehensive support and effective intervention against all forms of child trafficking.

The NIJ FY 2026 State and Local Collection and Reporting of Crime Data program invites proposals for research aimed at enhancing the accuracy of crime data collection and reporting. This funding opportunity seeks to identify common challenges and develop effective best practices to improve data quality across jurisdictions. Studies that analyze how agencies collect offense data to ensure alignment with actual events and strengthen data governance practices are particularly encouraged.

The Limited Competition grant supports High Impact Specialized Innovation Programs to enhance clinical and translational science capabilities at UM1 CTSA Program Hubs. Eligible applicants include primary UM1 CTSA hub organizations, aiming to address significant gaps in research and development. Successful proposals will foster foundational innovations for broader dissemination among CTSA hubs, paving the way for future advancements in clinical practices and research methodologies.

The Regional Conservation Partnership Program (RCPP) Alternative Funding Arrangements for FY 2026 aims to enhance NRCS conservation efforts through strategic partnerships. This initiative encourages collaboration among stakeholders to address critical natural resource issues across farms and watersheds. By co-investing in impactful projects, NRCS strives to improve resource management in designated Critical Conservation Areas, supporting both partners and producers in achieving sustainable outcomes.

The NCI Pathway to Independence Award (K99/R00) supports early-stage postdoctoral researchers aiming to transition to independent faculty positions. It encourages candidates with doctoral degrees in research or clinical fields to apply, particularly those in cancer control and prevention. This funding opportunity facilitates a quick shift from mentored research to independent careers, providing essential support for awardees to establish competitive research programs without leading their own clinical trials.

The NCI Pathway to Independence Award (K99/R00) aims to support early-stage postdoctoral researchers transitioning to independent faculty positions. This initiative focuses on talented individuals with doctoral degrees in research or clinical fields, providing essential NCI funding during this key career juncture. Researchers engaged in cancer control, prevention, and data sciences are encouraged to apply for this opportunity, which emphasizes experimental studies with human participants, thus aligning with NIH's clinical trial definitions.