Best Sioux Falls Grants for Nonprofits in South Dakota

This funding opportunity encourages applications for clinical observational studies focused on musculoskeletal, rheumatic, and skin diseases. It aims to gather essential data for designing future clinical studies, enhancing understanding of disease symptoms, progression, and patient outcomes. Observational studies supported by this initiative will contribute to the development of objective biomarkers and effective outcome measures. Applicants are invited to address key challenges in clinical project design, ensuring a robust foundation for subsequent clinical trials.

The Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) aim to support clinical trials that can be completed within a limited timeframe. This funding opportunity encourages a variety of exploratory studies that align with the NIAMS mission, focusing on interventions such as drugs, biologics, devices, and various therapies. Applications are due by 5:00 PM local time of the applicant organization.

The Ono Initiative Grant by the Ono Pharma Foundation supports innovative research in Chemical Biology, aiming to transform human health. It welcomes proposals from Principal Investigators (PIs) at nominated institutions, focusing on groundbreaking solutions and promoting the development of young scientists. Grants of up to $1,035,000 over three years are available, fostering collaboration and transformative research aligned with the foundation's mission.

The Patterson Foundation offers Assistance Dog Program Grants to support organizations providing service animals to veterans and individuals with disabilities. Funding is available for projects that expand capacity, personnel costs related to puppy training, and program support aimed at improving client experiences. Eligible organizations must be 501(c)(3) non-profits and can request grants up to $35,000 for capital projects or $10,000 for program support. Applications are accepted through a two-step process.

The Patterson Foundation Scholarship offers $4,750 annually to children and legal dependents, aged 24 and under, of full-time employees at Patterson Companies in the U.S., U.K., and Canada. Renewable for up to four years, this scholarship can total $19,000 for higher education at accredited institutions. All undergraduate degrees are eligible, and students can reapply even if they have previously been denied. A selection committee from Scholarship America, Inc. reviews applications each summer.

The Limited Competition K12 Mentored Research Career Development Program aims to support institutions in developing innovative career pathways for later-stage postdoctoral fellows and junior faculty. This initiative encourages applicants from those with existing Clinical and Translational Science Awards (CTSA) to foster independent research careers. By creating diverse opportunities across academia, industry, and government, the program enhances engagement in clinical and translational science research, ultimately contributing to significant advancements in health outcomes.

The Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional) aims to foster unique hub capabilities and research platforms to tackle critical gaps in clinical and translational science. Open to eligible organizations involved in the CTSA Program, this funding opportunity is crucial for laying groundwork for future advancements across CTSA Program Hubs. Applications are due by 5:00 PM local time, with Letters of Intent encouraged 30 days prior to the deadline.

U.S. Writers Aid Initiative

PEN America is an organization of writers and their allies, and that solidarity is never more important than when members of our literary community face crises. PEN America’s U.S. Writers Aid Initiative, part of the PEN America Writers Emergency Fund, offers grants for writers in the United States facing acute financial need following an emergency situation.

The U.S. Writers Aid Initiative is intended to assist fiction and nonfiction authors, poets, playwrights, translators, and journalists in addressing short-term financial emergencies. To be eligible, applicants must be professional writers based in the United States, and be able to demonstrate that this one-time grant will be meaningful in helping address a short-term emergency situation. The fund is limited, and not every application can be supported.

Grant decisions are made on a quarterly basis by a volunteer committee of literary peers in consultation with PEN America staff, using the following guidelines to evaluate professional credentials:

• Publication of one or more books. (Writers who are only self-published or published by a press that charges for publication are not eligible.)
• Multiple essays, short stories, or poems appearing in literary anthologies or literary journals (either online or in print) in the last two years.
• A full-length play, performed in a theater by a professional theater company. Productions in academic settings qualify if the author is not a student at the time of the production.
• Employment as a full-time professional journalist, columnist, or critic, or a record of consistent publication on a freelance basis in a range of outlets during the last two years.
• Contracted forthcoming books, essays, short stories, poems, or articles for which the name of the publisher can be provided.
• Other qualifications that support the applicant’s professional identity as a writer.

The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty in digestive disease research. This award aims to support independent careers in pancreatic cancer research by protecting a significant portion of the recipient's time for research activities. Eligible applicants must hold an MD, PhD, or equivalent and work at a North American institution, with AGA membership required. Strong encouragement is given to underrepresented groups.

The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.

The AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award provides $100,000 annually for three years to early-career faculty dedicated to gastric cancer research. Eligible candidates must have an MD, PhD, or equivalent and a full-time faculty position in North America. The award supports research in various areas related to gastric cancer, ensuring a minimum of 50% time commitment to the project, thus fostering independent careers in digestive diseases.

The American Diabetes Association's Postdoctoral Fellowship Awards aim to foster emerging leaders in diabetes research. With a focus on innovative research, these fellowships provide up to three years of funding, including a stipend and allowances. Eligible applicants must hold a recent advanced degree and conduct research at U.S. affiliated institutions. This initiative not only supports career development but also contributes significantly to the mission of preventing and curing diabetes.

The Zuckerman Postdoctoral Scholars Program fosters collaboration between leading scientific institutions in the U.S. and Israel by attracting top postdoctoral researchers. With a focus on STEM leadership, this program offers a unique two-year scholarship, allowing scholars to conduct research at participating Israeli universities and North American institutions. The initiative aims to strengthen academic ties, enhance research capabilities, and support the return of talented Israeli scholars to their home institutions, ultimately enriching the global scientific community.

The Tides Stronger Together Fund, under the Tides Foundation, provides essential support grants to fiscally sponsored partners focused on historically underserved communities. By building organizational capacity and leadership, the fund empowers community changemakers to address inequities and enhance sustainability. With a pooled funding model, it directly responds to the needs of over 120 partners, ensuring resources are effectively allocated where they are most impactful, ultimately fostering long-term community resilience.

The Lisa and Douglas Goldman Fund, established in 1992, supports charitable organizations that enhance society, focusing on democracy and civil liberties. The fund prioritizes projects that ensure equal citizen participation in the democratic process and protect civil liberties, especially those implemented nationally or across multiple states. It operates by invitation only and emphasizes flexible, informed grantmaking to qualified projects that align with its mission and values.

The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.

The Limited Competition Small Grant Program under the NCATS CTSA aims to enhance the research capabilities of scholars transitioning to independent academic translational scientists. This program supports diverse clinical and translational science projects, including pilot studies and methodology development. The R03 grants are designed for short-term projects with limited resources that generate preliminary data for future R01 applications, thereby fostering innovation and advancing health research.

The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.

About Us

Columbus Citizens Foundation celebrates Italian heritage and culture through a broad range of philanthropic and educational activities. The Foundation’s Scholarship program has supported thousands of deserving Italian American students, offering them a chance to fulfill their academic dreams and excel in their endeavors. Since 1929, the Foundation’s most public activity is organizing New York City’s annual Columbus Day Parade, the largest celebration of Italian-American heritage and achievement in the world. CCF offers many programs throughout the year celebrating Italian language, culture, history, and the many connections between Italy and the United States that extend across several centuries and continue to the present day.

CCF Medical School Scholarship

Since 2017, Columbus Citizens Foundation has been awarding scholarships to promising medical school students of Italian heritage. The scholarship that launched CCF’s medical school offerings in 2017 is primarily funded by, and candidates selected in partnership with, the Morgagni Medical Society, an organization founded in 1890 in order to foster the professional, intellectual, and economic development of Italian American physicians.

In 2021, CCF launched the Dr. Anthony S. Fauci Medical School Scholarship, to be awarded annually to Italian American students who exemplify the values and determination of Dr. Fauci. The scholarship supports students with great academic prowess seeking financial aid at the graduate level in medical and public health fields of study.

The USTA Player Development Excellence Grant supports aspiring U.S. tennis players by providing financial assistance based on performance and potential. Grants of up to $12,000 are awarded to players who meet specific criteria, encouraging their development into top 100 professionals. By utilizing USTA facilities and coaching, players can maximize their growth. The program aims to nurture young talent and ensure they have the resources necessary to succeed in competitive tennis.

The Julian U. Stein Lifetime Achievement Award honors a SHAPE America professional who epitomizes Dr. Stein's exemplary leadership in education, mentorship, and advocacy for individuals with disabilities. With over 45 years of dedication to the field, Julian Stein has made significant contributions through writing, public speaking, and community service. This award recognizes those who have demonstrated exceptional commitment to improving lives through physical activity and educational programming for individuals with disabilities.

Patagonia’s Corporate Grant supports grassroots organizations focused on bold, direct-action campaigns that address the root causes of environmental issues. The program emphasizes equity, inclusivity, and long-term change, targeting communities affected by environmental exploitation. Grants are awarded to innovative groups within the US and Canada, fostering civic engagement and measurable objectives. Patagonia prioritizes funding for initiatives that confront systemic bias and promote environmental justice, ensuring that diverse voices are represented in the environmental movement.

The New Music Creator Fund provides financial support to individual music creators across all genres, helping them advance their creative practice. This initiative covers costs associated with developing new work and collaborative projects. Applicants must be at least 21 years old and have three years of professional music experience. The fund aims to empower diverse music creators in the U.S. by facilitating the development of innovative musical ideas and fostering artistic collaboration.

The Music Teachers of Excellence (MToE) Award, managed by the CMA Foundation, recognizes outstanding public-school music educators. This prestigious award, with a $5,000 prize, aims to support teachers who inspire students and enrich their communities through music education. The application will open on September 3, 2025, allowing full-time music teachers with at least four years of experience to showcase their commitment and impact in the field. Stay tuned for more details!

The Special Excellence Annual Scholarship, offered by the CIRI Foundation, supports full-time students in 4-year undergraduate or graduate programs who demonstrate exceptional academic achievements and community service. With awards up to $20,000 for one academic year, this merit-based scholarship emphasizes the importance of maintaining a minimum GPA of 3.7 and encourages contributions to the Alaska Native community. This initiative fosters educational success and economic self-sufficiency among Alaska Natives and their descendants.

The Raven Fund Scholarships, offered by the CIRI Foundation, support educational aspirations for CIRI voting shareholders who are not original shareholders or descendants. Award amounts include $200 per credit for full-time students, up to $3,000 per term, and similar support for part-time students. Funds cover tuition, fees, books, supplies, and housing. Applicants must have a high school diploma, be enrolled in an accredited program, and maintain a minimum GPA of 2.0 to qualify.

The Raven Fund Jump Start Award, established by the CIRI Foundation, provides scholarships of up to $2,000 per year for CIRI voting shareholders who are high school students. Eligible applicants must be enrolled in a recognized post-secondary education program, maintaining a minimum GPA of 2.0. The funding covers direct educational costs such as tuition, books, and housing. The award allows for multiple applications within the year, encouraging ongoing educational pursuits.