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Best Grants for Nonprofit Human Services in South Carolina

Looking for grants for Nonprofit Human Services in South Carolina? Find the perfect grant for your nonprofit on Instrumentl.

138

Available grants

$4.8M

Total funding

$11K

Median grant

138 grants
$4.8M total
$11K median

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138 Results based on applied filters

James C. Stewart Charitable Foundation Grant

James C Stewart Charitable Foundation
Private
United States
Approximately US $10,000
The James C. Stewart Charitable Foundation Grant supports various charitable causes primarily in Tucson, Arizona, and Southern California. Founded by James Stewart, who was dedicated to uplifting the community and promoting the arts, the foundation provides an average grant of $10,000, awarding around five grants annually. Eligible organizations must be 501(c)(3) exempt. The foundation emphasizes arts, education, environment, health, human services, and public benefit, continuing Stewart's legacy of generosity.
Art & Culture Humanities & Social Science Education +7 more

Republic Services: Community Grant Program

Republic Services Charitable Foundation
Corporate
Puerto Rico, United States
Unspecified amount
The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.
Disaster Relief / Humanitarian Aid Community / Public Safety Human & Social Services

Louis N. Cassett Foundation Grant

Louis N. Cassett Foundation
Private
United States
Unspecified amount
The Louis N. Cassett Foundation provides grants to support a variety of charitable endeavors, particularly focusing on organizations in the Philadelphia and South Florida areas. As a private foundation operating under Section 501(c)(3) of the Internal Revenue Code, it empowers tax-exempt organizations to apply for funding. The Foundation does not impose religious affiliation requirements on recipients, ensuring that support is inclusive and aimed at a broad range of charitable, cultural, and educational projects.
Basic Human Needs Poverty Alleviation & Services Education +5 more

Towsley Foundation Grants

Harry A. & Margaret D. Towsley Foundation
Private
United States
More than US $250,000
The Towsley Foundation Grants support initiatives that enhance community welfare and sustainability, focusing on diverse fields such as education, health, and the arts within Michigan. With a commitment to effective philanthropy, the foundation prioritizes projects that demonstrate creativity and strategic impact. Eligible organizations must operate in Michigan and adhere to specific funding guidelines, fostering financial sustainability. Grants are allocated based on project merit and organizational capacity, reinforcing the foundation's mission to improve lives through thoughtful partnerships.
Art & Culture Civic Affairs Community Development & Revitalization +4 more

Elizabeth Raymond Ambler Trust Community Grant

Elizabeth Raymond Ambler Trust
Private
United States
Unspecified amount
The Ambler Trust Grants, provided by the Elizabeth Raymond Ambler Trust, support various sectors including education, health, arts, culture, and environmental initiatives. Eligible applicants include municipal, religious, charitable, benevolent, or educational organizations as determined by the Trustees. These grants aim to enhance community welfare and promote beneficial projects, ensuring a positive impact across diverse fields.
Education Art & Culture Human & Social Services +5 more

Mifflin Memorial Fund Grant

George H & Jane A Mifflin Memorial Fund
Private
United States
Unspecified amount
The Mifflin Memorial Fund Grant supports nonprofit organizations in human services and education, particularly those serving low-income and minority populations. This private fund also contributes to environmental and conservation initiatives, and occasionally cultural organizations for specific projects. Eligible applicants must be tax-exempt nonprofits, ensuring that grants are directed towards impactful community services and educational opportunities.
Education Human & Social Services Environmental Conservation +1 more

Jay L. Smith Family Foundation Grants

Jay L. Smith Family Foundation
Private
United States
Unspecified amount
The Jay L. Smith Family Foundation provides grants to tax-exempt non-profit organizations in the United States, primarily focusing on healthcare, family values, and supporting the disadvantaged. With a strong commitment to Alzheimer's research, the foundation has funded various initiatives including elderly care, domestic violence prevention, and cancer research. Their mission is to enhance the quality of life for individuals and communities through meaningful contributions, aiming to address critical social issues and promote well-being.
Senior Services Suicide Prevention Dementia & Alzheimer’s Disease +6 more

Semnani Family Foundation Grants

Semnani Family Foundation
Private
Afghanistan, Bosnia and Herzegovina +20 more
Unspecified amount
The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.
Homelessness Services Food Access & Hunger Diseases & Conditions +14 more

Robert E & Evelyn McKee Foundation Grant

Robert E & Evelyn McKee Foundation
Private
United States
Unspecified amount
The Robert E & Evelyn McKee Foundation Grant focuses on charitable purposes, primarily supporting organizations that qualify under 501(c)(3) of the IRS Code. It awards funds in various areas including civic, cultural, education, healthcare, and youth activities. Eligible recipients are local charities and certain selected colleges for scholarships. However, the foundation does not fund other foundations, organizations outside the U.S., or individual financial aid. Awards are guided by IRS minimum requirements.
Civic Affairs Episcopalism Hospital Care +9 more

McClure Family Foundation Grant

McClure Family Foundation
Private
United States
Unspecified amount
The McClure Family Foundation Grant honors the legacy of Charles and Dorothy McClure by supporting nonprofit organizations that strengthen families and communities. The foundation aims to promote the arts, historic preservation, education, faith-based initiatives, and the well-being of mankind. Eligible applicants include public charities, governmental units, and established churches. The foundation values personal connections with applicants and encourages endeavors that foster community responsibility and individual leadership.
Art & Culture Historic Preservation Education +2 more

H.S. Lopez Family Foundation Grant

Hs Lopez Family Foundation
Private
United States
Unspecified amount
The H.S. Lopez Family Foundation Grant focuses on funding innovative projects that enhance the quality of life, primarily in Arizona. With an emphasis on health, education, and welfare, the foundation aims to support not-for-profit organizations that address critical community needs. Grants are awarded to initiatives that demonstrate potential for lasting impact and community benefit, encouraging sustainable support beyond the foundation's involvement.
Education Health & Medicine Human & Social Services

Enterprise Mobility™ Philanthropic Giving

Enterprise Holdings Foundation
Corporate
Canada, France +5 more
Unspecified amount
The Enterprise Mobility™ Philanthropic Giving program focuses on enhancing community engagement through grants aimed at supporting health, education, arts, and disaster relief initiatives. Only Enterprise Mobility team members and their spouses or domestic partners who volunteer with a nonprofit can apply for funding. The program prioritizes sustainable projects that uplift local communities and address pressing social issues, fostering a culture of responsibility and giving back to society.
Disaster Relief / Humanitarian Aid Workforce Preparation & Job Readiness Economic Services & Development +4 more

Koch Foundation: General Proposals

Charles Koch Foundation
Private
United States
Unspecified amount
The Charles Koch Foundation invites innovative proposals for research that aligns with its vision of social progress and mutual benefit. Focused on supporting 501(c)(3) non-profit public charities and universities in the U.S., the Foundation emphasizes original projects of high standards. While it welcomes a broad range of ideas, it typically does not fund for-profit ventures, overhead costs, or certain areas like medical treatment and political activities.
Community Services Human & Social Services Social Justice / Human Rights +1 more

Cyrus M. Quigley Foundation Grant

Cyrus M. Quigley Foundation
Private
United States
US $1,000 - US $7,500
The Cyrus M. Quigley Foundation Grant supports tax-exempt organizations that empower young people through initiatives focusing on courage, self-reliance, and service. Since its inception in 1993, the foundation has awarded over $300,000 in grants, with amounts ranging from $1,000 to $7,500. The foundation emphasizes physical challenges and community service to help develop essential life skills. Grant proposals are accepted annually until the third Friday in April, with decisions communicated by May 31.
Wellness & Healthy Living Cross-Cultural Understanding & Exchanges Civic Leadership Development +3 more

Saw Island Foundation: Social Change, Faith-Based and Special Grants

Saw Island Foundation
Private
United States
Unspecified amount
The Saw Island Foundation provides Social Change, Faith-Based, and Special Grants to nonprofit organizations focused on community betterment. They support initiatives that enhance economic security and promote Christian education. While active engagement is primarily in the San Francisco Bay Area, they welcome extraordinary projects aligned with their mission. Eligible applicants must be 501(c)(3) tax-exempt organizations. The foundation does not fund individual grants, political activities, or lobbying efforts.
Social Justice / Human Rights Economic Rights, Justice, & Mobility Christianity +1 more

LCCF Community Enrichment Grants Program

Laurens County Community Foundation
Corporate
Laurens County, South Carolina
Up to US $2,500
The Laurens County Community Foundation (LCCF) Community Enrichment Grants Program aims to enhance the quality of life for Laurens County citizens. Grants are available for initiatives that support education, job training, and community health. Eligible projects may address issues like homelessness, teen pregnancy prevention, and addiction treatment. The program prioritizes proposals benefiting a larger population and excludes funding for salaries, political campaigns, and construction projects. Interested individuals and organizations are encouraged to apply.
Education - K through 12 Literacy Workforce Preparation & Job Readiness +14 more

Donald & Ruby Branson Foundation Grant

Donald & Ruby Branson Foundation
Private
United States
Unspecified amount
The Donald & Ruby Branson Foundation Grant aims to promote environmental, educational, and social progress in America. Established by the Branson family, it seeks to instill values of community involvement and charitable responsibility in future generations. The foundation primarily supports tax-exempt organizations under Section 501(c)(3) and emphasizes the importance of education and environmental stewardship, ensuring a cleaner and more attractive world for all.
Environment Education Environmental Conservation +1 more

Robert B. and Ruth K. Lee Foundation Grant

The Robert B. and Ruth K. Lee Foundation
Private
Greenville County, South Carolina
US $2,000 - US $5,000
The Robert B. and Ruth K. Lee Foundation Grant aims to enhance the quality of life in Greenville County, South Carolina. Established in 2000, the foundation supports diverse areas including arts, education, health, and human services. With no geographic limitations, it primarily funds programs benefiting the local community. Grants typically range from $2,000 to $5,000, emphasizing initiatives for the elderly, children’s programs in the arts, and literary projects. Organizations must be 501(c)(3) exempt to be eligible.
Art & Culture Humanities & Social Science Education +11 more

Yawkey Foundation: Strategic Investment Grant

Yawkey Foundation
Private
Barnstable County, Massachusetts, Bristol County, Massachusetts +6 more
US $250,000 - US $1,000,000
The Yawkey Foundation's Strategic Investment Grant supports nonprofit organizations aiming for strategic growth through board-approved plans. Grants, ranging from $250,000 to $1 million, may fund regional expansions, collaborative efforts among nonprofits, and organizational mergers. Initial Proposals are highly competitive and must demonstrate strong leadership, proven impact, and alignment with the Foundation's Areas of Giving. Review periods for proposals can take 6-12 months, during which feedback is not provided.
Health Care Access & Delivery Education Human & Social Services +4 more

Tech for Good Impact Awards

Zendesk Inc
Corporate
Afghanistan, Albania +176 more
US $10,000 - US $50,000
The Zendesk Tech for Good Impact Awards support nonprofits by providing them with essential software, grants, and pro bono assistance to enhance their impact on vulnerable populations. The program aims to foster community connections, promote resilience during crises, and create career pathways in technology. Eligible organizations must demonstrate a commitment to utilizing technology in their services, enhancing their ability to support beneficiaries effectively. This initiative empowers nonprofits to leverage technology for greater social good.
Technology Access & Digital Literacy Community Services Career / College Preparation +3 more

SBB Research Group Foundation Grant

SBB Research Group Foundation
Private
United States
US $1,000 - US $5,000
The SBB Research Group Foundation Grant supports 501(c)(3) organizations addressing unmet needs through sustainable strategies. Winners are selected monthly, receiving $5,000, while other finalists are awarded $1,000. The foundation collaborates with various partners and has a strong commitment to community service. Organizations are encouraged to apply early, as prior applicants can be reconsidered in subsequent months. This initiative aims to empower impactful initiatives across diverse sectors.
Community Services

Latham Foundation for the Promotion of Humane Education Grant

Latham Foundation for the Promotion of Humane Education
Private
United States
Up to US $10,000
The Latham Foundation for the Promotion of Humane Education, established in 1918, emphasizes humane education to foster kindness and respect for all living beings. With a focus on innovative programs for teenagers and animal-assisted activities, the foundation invites U.S. organizations, particularly nonprofits, to apply for grants. However, funding does not extend to capital projects, salaries, or conference travel. Latham aims to instill core values that promote compassion within communities and across nations.
Animal Welfare - General Human-Animal Interactions & Therapy Service Animals

SFC Charitable Foundation Grant

Singing For Change Charitable Foundation
Private
United States
US $1,000 - US $10,000

Singing for Change Grant Program

Singing for Change empowers people to become more self-sufficient.

Singing for Change supports nonprofit organizations that inspire, empower, and equip people to become more self-sufficient.

Our grantees encourage personal growth among people who are marginalized. They care about the community as a whole, as well as promote the belief that collectively, people can bring about positive change and sustainable self-sufficiency through connected, diverse communities.

Most likely to be considered are organizations that keep their overhead low and collaborate with other groups in their community to find innovative ways of solving a common problem.

Singing for Change (aka SFC Charitable Foundation, Inc.) was created by Jimmy Buffett in 1995, and receives one dollar from each ticket Jimmy sells at his shows. We envision a world where nonprofit organizations, large and small, provide compelling opportunities for individuals to discover their power to make a difference. The foundation promotes work on the forefront of social change - helping people and communities become smarter, safer, stronger, healthier, and whole. 

Singing for Change (SFC) partners with progressive, community-based organizations addressing the root causes of social or environmental problems. We recently narrowed our focus to projects designed to promote self-sufficiency. 

Specifically, we look for groups that are: 

  • Working to engage individuals in their communities 
  • Helping people realize their full potential
  • Creating lasting change in the communities they serve

We will fund operating expenses for those organizations that we feel are accomplishing these goals.

Areas Of Interest:

Children and families: Grants are awarded to programs fostering self-sufficiency and stability. Individual therapy is not funded, nor are therapeutic or recreational camps or wish-fulfillment programs.

Disenfranchised groups: SFC defines these groups as people who have been marginalized in society because of their low levels of skill, education or income, people with disabilities, and people who are homeless. 

Grants range in size from $1,000.00 to $10,000.00.

Academic Success & Enrichment Family Services Child Welfare Services +6 more

Animal Welfare Organizations Grants

Petco Love
Corporate
United States
Unspecified amount
The Petco Foundation offers grants aimed at animal welfare organizations, focusing on enhancing adoption and medical care initiatives. With a commitment to lifesaving programs, they invest in organizations that demonstrate accountability and significant impact in their communities. Eligible applicants include non-profit organizations, municipal agencies, and SPCA/humane societies that provide sheltering services. The grant cycle allows for one proposal submission per year, ensuring support for those dedicated to improving the welfare of companion animals.
Animal Welfare - Domestic Animals & Pets

Scaife Family Foundation Grant

Scaife Family Foundation
Private
United States
Unspecified amount
The Scaife Family Foundation Grant has been supporting vulnerable community members for nearly 40 years, providing over $180 million in donations to non-profits. The Foundation aims to match organizations with aligned goals, focusing on women and children, addiction prevention, and animal welfare. It offers grants for general operating and program support, prioritizing impactful programs that address societal issues. Notably, the Foundation considers proposals that foster healthy relationships and promote treatment for addiction, enhancing the welfare of both humans and animals.
Children’s Health & Pediatrics Children’s Mental Health Child Welfare Services +6 more

AI for Economic Opportunity Fund

Gitlab Foundation
Private
United States
Up to US $250,000
The AI for Economic Opportunity Fund, established by the GitLab Foundation, aims to catalyze transformative economic opportunities using advanced AI technologies. This funding round invites bold proposals that leverage AI to enhance economic mobility, improve service delivery, and create new educational pathways. Grantees will receive $250,000 in funding, technical support, and access to a network of practitioners. The fund seeks projects that demonstrate ethical awareness and promote fairness in AI deployment.
Economic Rights, Justice, & Mobility Artificial Intelligence (AI) Economic Services & Development

OpenAI A People-First AI Fund

Openai Inc
Private
United States
Unspecified amount
The OpenAI A People-First AI Fund supports U.S.-based nonprofits with 501(c)(3) status, focusing on AI literacy, community innovation, and economic opportunity. It aims to enhance public understanding of AI, promote participatory design in AI applications by communities, and expand access to meaningful work through inclusive practices. Organizations at all stages of AI adoption are encouraged to apply, especially those addressing the needs of traditionally marginalized populations. This initiative emphasizes equitable distribution of AI benefits.
Economic Services & Development Technology Access & Digital Literacy Artificial Intelligence (AI) +1 more

Grants for Nonprofit Human Services in South Carolina Highlights

Looking for grants for nonprofit human services in South Carolina?


Read more about each grant below or start your 14-day free trial to see all grants for nonprofit human services in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Grants for Nonprofit Human Services in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Grants for Nonprofit Human Services in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Grants for Nonprofit Human Services in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081