Best Grants for New Nonprofits in South Dakota

The IEN-WMAN Mini-Grant Program provides crucial financial support to Indigenous communities and grassroots organizations impacted by mining in the U.S. and Canada. With over $200,000 distributed annually in $4,000 grants, the program aims to address mining-related environmental and health issues. Priority is given to proposals that demonstrate a direct impact on affected communities, particularly Indigenous-led initiatives, ensuring that financial assistance is directed where it is most needed.

The H. Wayne VanAgtmael Cosmetology Scholarship, established in 2005 by Wayne Van Agtmael's family, honors his legacy in the cosmetology field. This scholarship supports high school graduates from the Tri-Cities pursuing a cosmetology degree, focusing on financial need and academic achievement. Applicants must provide transcripts and additional required documents. The scholarship aims to empower students, particularly those who are the first in their families to succeed beyond high school, in their educational journeys.

About Alex’s Lemonade Stand Foundation

Alex's Lemonade Stand Foundation (ALSF) emerged from the front yard lemonade stand of 4- year-old Alexandra “Alex” Scott, who was fighting cancer and wanted to raise money to find cures for all children with cancer. Her spirit and determination inspired others to support her cause, and when she passed away at the age of 8, she had raised $1 million. Since then, the Foundation bearing her name has evolved into a national fundraising movement. Today, ALSF is one of the leading funders of pediatric cancer research in the U.S. and Canada, funding research projects and providing programs to families affected by childhood cancer. ALSF is one of the only childhood cancer research organizations that has been given the NCI peer-reviewed funder designation for rigorous selection of research grants. The mission of ALSF is to change the lives of children with cancer through funding impactful research, raising awareness, supporting families, and empowering everyone to help cure childhood cancer.

Bio-Therapeutic Impact Award

The Bio-Therapeutic Impact Award accelerates the development of clinical trials for promising biologic approaches to treating childhood cancer. These approaches include, but are not limited to, immunotherapy, gene therapy and small molecules. The award, intended for investigators who are initiating clinical trials, totals the maximum of $1.8 million awarded over three years.

The CFSI Education Fund Scholarship, offered by the Community Foundation of Southern Indiana, awards multiple $2,000 non-renewable scholarships to students over 25 who have some college experience but no degree. This program aims to support those returning to complete their post-secondary education, including vocational training. By empowering individuals from Clark and Floyd counties, the scholarship fosters educational advancement and community growth, reflecting the foundation's commitment to enriching lives through learning.

About

Mission, Vision & Values

To enhance our community through philanthropy.

We aspire to co-create diverse, meaningful and innovative charitable giving that yields an exponential positive impact within local communities and beyond.

Coopey Boys’ Memorial Fund

About the fund

The Coopey Boys, Raymond Peter and Lauritz Martin, were born with hemophilia, a genetic disorder that impairs the body’s ability to make blood clots. Sadly, they both died at an early age. The Coopey Boys’ Memorial Fund benefits Corvallis students who suffer from a physical handicap or serious chronic health problem.

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

Society of Hospital Medicine: Junior Investigator Award

SHM’s Junior Investigator Award was created to recognize junior/early-stage investigators. Junior/early-stage investigators are defined as faculty in the first 7 years of furthest postgraduate training. Applicants must be a hospitalist and a clinician investigator or non-clinicians (i.e., a PhD) researching Hospital Medicine relevant topics. Nominations from mentors and self-nominations are both welcome. Applicants may request feedback about their applications after adjudication of the winner. The winner will present the Junior Investigator Award commendation talk (30 minutes) during SHM Converge.

About Lions Club International FoundationLions Clubs International Foundation (LCIF) provides grants that empower the service of our members. Since its inception in 1968, LCIF has awarded more than US$1.3 billion in grant funding.  Mission :Our mission is to empower Lions clubs, volunteers and partners to improve health and wellbeing, strengthen communities, and support those in need through humanitarian service and grants that impact lives globally, and encourage peace and international understanding. And we fulfill it every day, everywhere we serve.Lions Club International Hunger Grant ProgramHunger Grants focus on strengthening infrastructure and providing essential equipment for Lions’ hunger-relief efforts. These grants empower Lions to support vital initiatives such as school feeding programs, food banks and feeding centers, ensuring that those in need receive the nourishment they require. These grants support infrastructure and equipment acquisition for Lions’ projects focused on alleviating hunger.Grant Examples: 

• Construction or expansion of food banks, feeding centers and food storage facilities.
• Purchase of refrigerators and freezers to store perishable food items.
• Vehicles to transport, collect and deliver food.

The FX Storytelling Legacy Scholarship, established by the United Negro College Fund, honors the renowned director John Singleton. This initiative aims to empower aspiring filmmakers and screenwriters by providing financial support of $5,000 to four selected students during their junior year, with the possibility of an additional $5,000 in their senior year. The program also includes mentorship opportunities with FX employees, fostering professional development and engagement in the film and television industry.

This program aims to enhance education for healthcare professionals regarding new therapies and patient management in ulcerative colitis (UC). It focuses on multi-channel educational strategies to address the evolving landscape of UC treatment. Key areas include educating on new oral therapies, transitioning to advanced therapies, and managing isolated proctitis. Organizations such as healthcare institutions and medical education companies are eligible to apply, ensuring a comprehensive approach to improving UC care.

The Multiple Sclerosis Clinical Care Physician Fellowship: Pediatric Care, offered by the National Multiple Sclerosis Society, aims to enhance the training of physicians in providing specialized care for pediatric patients with MS. This one-year post-residency program emphasizes direct patient care and multidisciplinary collaboration. Participants will learn under the supervision of MS specialists, gaining essential skills to improve clinical practices and contribute to the MS community, ultimately leading to better outcomes for those affected by this condition.

The James W. Junior and Jane T. Brown Scholarship, established by Jane and James Brown in 2006, offers financial support to adult students over 21 in the Tri-Cities. This scholarship aims to ease the financial burdens faced by those returning to education. Applicants must demonstrate financial need and provide necessary documentation, including transcripts and a Student Aid Report. The program encourages recipients to assist others in their educational journeys, fostering a cycle of support in the community.

The Alzheimer’s Association and ASNR Imaging Research Grant focuses on advancing imaging research in Alzheimer’s and other neurodegenerative diseases. This partnership aims to support early-stage pilot projects that develop novel imaging tools and innovative data analysis methods. Up to three proposals will be funded, with each award capped at $200,000 for one year, promoting significant advancements in the field and enhancing research capabilities for better understanding of dementia.

The Lawrence F. and Barbara J. Dickman Scholarship supports Zeeland High School graduates pursuing higher education in the U.S. on a medical track. Applicants must demonstrate financial need and can reapply if they have received the award previously. Recommendations from teachers or counselors are required. Scholarships are usable starting in the fall of the announcement year and unaccepted scholarships will be forfeited after December 31. This scholarship aims to foster future healthcare professionals.

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

The SHC Student Research Grant supports research utilizing herbarium resources across various taxa, including plants, fungi, lichens, and algae. Eligible projects may involve fieldwork, data collection, or meta-analysis of herbarium data, with an emphasis on enhancing herbarium collections. Three grants are awarded annually: two for $500 and one specifically for undergraduates for $250. Applicants must be student SHC members with projects likely to lead to publication.

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

The Growing Convergence Research (GCR) initiative by the National Science Foundation (NSF) promotes innovative solutions to complex societal and scientific challenges through multidisciplinary collaboration. By integrating diverse expertise, GCR aims to address specific problems and foster new research paradigms. Proposals must outline a five-year plan, divided into two phases, with budgets not exceeding $1.2 million for Phase I and $2.4 million for Phase II. Successful projects are expected to lead to transformative advances in science and technology.

The AAAAI Foundation Faculty Development Award provides $300,000 in funding over three years to support the growth of junior faculty in the fields of allergy and immunology. This initiative, spearheaded by the American Academy of Allergy, Asthma & Immunology, aims to foster the development of future leaders and independent researchers dedicated to combating asthma and allergic diseases through impactful research.

The Chrysalis Project Program, hosted by the American Academy of Allergy, Asthma & Immunology (AAAAI), offers an exciting opportunity for U.S. and Canadian medical students and residents to explore the field of allergy and immunology. Participants can attend the AAAAI Annual Meeting free of charge, enhancing their understanding and interest in this vital subspecialty. This initiative aims to cultivate the next generation of allergists, fostering professional growth and engagement in allergy and immunology.

The Solidarity Fund Grant, part of the Black Feminist Fund, aims to empower Black feminist movements by providing essential resources. Acknowledging the historical underfunding of these movements, the fund supports groups led by Black women, girls, and gender-expansive individuals. It focuses on solidarity efforts that foster collaboration and joint campaigns, enabling activists to drive social change. This initiative is crucial for advancing justice, self-determination, and equity within communities, ensuring that Black feminist visions are amplified and sustained.

The Burroughs Wellcome Fund's Next Gen Pregnancy Initiative Grants aim to enhance research on pregnancy outcomes, addressing issues such as preterm birth and maternal health. With an emphasis on fostering diverse scientific collaboration, the initiative supports innovative proposals from researchers across various disciplines. Each grant offers up to $500,000 over four years, encouraging groundbreaking studies that explore the biological and environmental factors affecting pregnancy. This initiative seeks to improve health outcomes through informed research and interdisciplinary partnerships.

The Family Unification Program (FUP) aims to assist families and youth at risk of homelessness by providing Housing Choice Voucher (HCV) assistance. It targets families facing housing issues that could lead to out-of-home placement for children and youth aged 18-24 who have aged out of foster care. The program offers flexible voucher durations, with extensions available under specific conditions, ensuring support for those in need of stable housing.

About Us

The Elk County Community Foundation was started in the late 1990’s by a group of business and civic leaders, with the support of the Stackpole-Hall Foundation, who recognized the need for creating a perpetual funding stream to support Elk County—now and in the future. The Foundation was incorporated in 2000 and a year later was classified as a 501(c)(3) nonprofit organization.

The Foundation provides donors with a simple but powerful and highly personal approach to achieving their philanthropic goals while enhancing the quality of life for the people of Elk County.

The Community Foundation makes it easy for individuals, businesses, and organizations to establish a scholarship fund. Your fund can be created in as little as one meeting, with a short fund agreement, and a single gift. Or your fund can be set up with an initial gift that is added to in the future. We manage all the administrative details of your fund for you.

By establishing a uniquely-named scholarship, you have the ability to designate eligibility requirements including education level, the field of study, geographic area, etc. Many scholarships are established to honor parents, a family member, or someone who influenced your life.

Most scholarship funds at the Foundation are permanent endowments, with the annual earnings used to provide the scholarships

Tyler Bender EMS Scholarship Fund

Tyler Bender recently graduated from the Center for Emergency Medicine, and he felt compelled to give back by starting this scholarship to encourage other individuals to consider the EMS field. There is a constant demand for well-trained and qualified EMS professionals. Tyler hopes that this scholarship fund will help attract individuals to the field and alleviate a shortage of EMS personnel.

Amount: $500 annually

The Colleen Maher Inspirational Scholarship supports individuals with intellectual disabilities, aged 18-25, who are current students or graduates of Rockford Public Schools. This scholarship empowers them to pursue post-secondary education and develop skills for independent living. Inspired by Colleen Maher, who overcame challenges associated with Down syndrome, this initiative aims to ensure that others like her can access educational opportunities and work towards their dreams, fostering a more inclusive community.

The FY26 Bollards Competitive Grant Program aims to enhance pedestrian safety by funding bollard installation projects. This initiative targets areas frequented by large crowds to prevent injuries and potential acts of terrorism. Eligible applicants include State Departments of Transportation and local government entities, with a 100% federal funding share for projects. This program is vital for improving public safety in urban environments.

The Ruth E. Reed Nursing Scholarship, established by the Community Foundation of the Northern Alleghenies, honors the legacy of Ruth Reed, a dedicated nurse. This scholarship supports students from Elk, Warren, and Clearfield Counties pursuing nursing degrees, with a GPA requirement of 2.5 or higher. With an annual award of approximately $500, it encourages future generations to pursue careers in nursing while recognizing the importance of continued education in healthcare.

The George C. Cotzias, MD, Memorial Fellowship, established by the American Parkinson Disease Association, supports young neurologists in their research and treatment of Parkinson's disease and related disorders. Funded at $125,000 annually for three years, this fellowship encourages recent graduates to develop their careers in neurology, ensuring they have the mentorship and resources necessary for success. The fellowship aims to honor Dr. Cotzias' legacy and inspire the next generation of leaders in neurology.