Best Operating Grants for Nonprofits in South Dakota

The Judith Graham Pool (JGP) Postdoctoral Research Fellowship, established by the National Bleeding Disorders Foundation (NBDF) in 1972, supports groundbreaking research in bleeding disorders. It offers up to $52,000 annually for two years to candidates engaged in pre-clinical or basic science studies related to hemophilia and other inherited bleeding disorders. The fellowship aims to advance understanding and treatment options, including gene therapy, while fostering new scientific talent in the field.

The National Institute on Aging (NIA) is set to release a Notice of Funding Opportunity (NOFO) aimed at advancing the discovery of in vivo chemical probes for brain targets. Collaborating institutes include the National Eye Institute (NEI), National Institute on Drug Abuse (NIDA), and National Institute of Mental Health (NIMH). The initiative seeks to foster research into small molecules and novel biological targets related to brain diseases, encouraging innovative projects and collaborations.

The 2026 Radiation Oncology Institute- Innovation Awards aim to advance cancer treatment by integrating radiation therapy with immunotherapy. Researchers are invited to submit proposals that explore optimal combinations of these modalities to enhance patient outcomes. Funding of up to $100,000 over two years will support projects focused on identifying effective treatment strategies, understanding mechanisms of synergy, and improving access to care. This initiative represents a significant opportunity for innovative research in oncology.

The MLK Commission Scholarship Fund, managed by the San Antonio Area Foundation, supports current high school seniors from Bexar County who aspire to pursue higher education. This renewable scholarship is available for full-time or part-time undergraduate studies at accredited institutions in the U.S. Applicants must maintain a minimum GPA of 2.5 and demonstrate residency and citizenship requirements. The fund aims to empower youth and enhance community growth through educational opportunities.

The Mrs. Leon Camp Scholarship Fund, established by the San Antonio Area Foundation, supports students pursuing education degrees. Eligible applicants include high school seniors and current college students in the USA. The scholarship is renewable for up to three years, contingent upon maintaining a 2.5 GPA and full-time enrollment. This initiative aims to empower future educators and ensure financial accessibility for those dedicated to teaching, contributing to the community's educational growth.

The Nemo Herrera Scholarship Fund, managed by the San Antonio Area Foundation, supports graduating high school seniors pursuing further education in any field. This scholarship aims to assist those who demonstrate academic merit and involvement in extracurricular activities, particularly students from Lanier High School. As a non-renewable scholarship, it covers tuition, fees, and books, ensuring that financial barriers do not prevent deserving students from achieving their academic goals.

Charles and Beatrice Kulier Scholarship

Graduating senior or graduating early college student who attends public, private, or home school in the primary service area of the Community Foundation

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Sidney High School Alumni Scholarship

Selection based upon:

• Financial need; academic ability; community, religious, and school service; recommendations.

Must be enrolling in a trade school or pursuing a two-year or four-year degree.

Awards

• One $2,000 scholarship

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Medical & Health Professions Scholarship

Applicants must be pursuing a certificate or an Associate’s, Bachelor’s, or Master’s degree in medical and associated health professions.

Selection based upon (in order of priority):

• Financial need, academic ability, community and school service, and recommendations.

Awards

• Two $1,500 scholarships

David Wiersema Memorial Scholarship

Graduating home school senior or graduating high school or early college student from one of the following high schools: Black River, Hamilton, Holland Christian, Holland High School, Saugatuck, West Ottawa, Zeeland East, or Zeeland West.

The Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration (AMD) provides $300,000 in funding to U.S. researchers exploring novel treatments and understanding of AMD. This initiative, co-funded by partners such as the American Macular Degeneration Foundation, encourages high-risk, high-gain research that could lead to significant advancements in AMD therapies. Each award is designed to support innovative projects that are not yet in clinical trials, fostering groundbreaking work in vision science.

The Disney Award for Amblyopia Research, funded by Research To Prevent Blindness Inc, aims to advance research in amblyopia diagnosis and treatment. Grants of up to $150,000 will support exceptional ophthalmic scientists conducting significant research. Eligible nominees include U.S. researchers from various academic ranks, with a focus on independent research. Proposals should highlight relevance to amblyopia's pathophysiology, diagnosis, or treatment, with awards available until Spring 2025.

The Medical Student Eye Research Fellowship offers a unique opportunity for medical students to dedicate a year to research in ophthalmology, focusing on any vision-related topic. Supported by Research to Prevent Blindness and other partners, the fellowship includes a $30,000 grant and potential additional funding for relocation. Eligible candidates must be U.S. citizens or permanent residents and be nominated by RPB-supported Chairs. The program aims to promote diversity and innovation in vision research.

The Stein Innovation Award supports innovative vision research by providing funding to Department of Ophthalmology faculty and other researchers. With deadlines in January and July, the award encourages projects that advance the understanding of the visual system and related diseases. Eligible candidates must be affiliated with U.S. institutions of higher education, and prior nomination forms are required for application acceptance. This initiative aims to foster groundbreaking research in the field of ophthalmology.

The Helen M. McLoraine Foster Care and Emancipated Youth Scholarship provides financial support for youth from the foster care system in Colorado. With a minimum award of $1,000, the scholarship is aimed at those pursuing post-secondary education, including trade schools and universities. Recipients are selected based on academic performance, resilience, and financial need, ensuring that deserving individuals receive the assistance they need to succeed in their educational goals.

The NASPGHAN Foundation/NASPGHAN George Ferry Young Investigator Development Award supports promising clinical, quality improvement, translational, or basic science research focused on gastrointestinal tract diseases, liver, pancreas, and nutritional disorders in children. Eligibility includes being a NASPGHAN member for at least two years, having a recent fellowship, and holding a junior faculty position. This award fosters innovative research to enhance pediatric gastroenterology and improve child health outcomes.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Marcia McKenzie Pay It Forward Scholarship

This scholarship is open to all majors, with priority given to women returning to school at Shasta College, or CSU Chico.

The Marcia McKenzie ‘Pay It Forward’ Scholarship Fund honors Marcia’s strong belief in a college education to further a person’s career goals and life path. She was the first of her family to attend and graduate from college, and benefitted throughout her life from that education. Years after her bachelor’s degree, she commuted to CSU, Chico to obtain a master’s degree while teaching full time at Shasta College. 

A wonderful mother and scratch cook, this scholarship was organized by her daughters and niece to honor her unwavering educational legacy. This scholarship is open to all majors, with preference given to applicants with an articulated career path, and life or community experiences that have delayed but clarified career intentions.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Pucek Family Scholarship Endowment Fund

This fund was established in honor of Bill, Jeannette, and Sidney Pucek.

Scholarship awards from this fund aim to benefit and support North State students pursuing an associate degree or certification in a vocational program.

The Crohn's & Colitis Foundation/NASPGHAN IBD Young Investigator Award supports early-career researchers in inflammatory bowel disease (IBD). This three-year grant offers mentorship and funding up to $60,000 annually, plus additional support for research-related expenses. Eligible applicants must hold an MD or PhD, demonstrate relevant research experience, and commit at least 65% of their time to the project. The award also facilitates access to IBD Plexus resources, enhancing research capabilities in the field.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Global Concepts Enterprise, Inc. Founders’ Scholarship

• Graduating high school senior, graduating early college student, or currently enrolled college or vocational/technical school student
• Enrolled or enrolling at any accredited post-secondary educational institution (including vocational/technical school) within the United States
• Financial need, a consideration (encouraged to submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• Age 25 or under
• The dependent child of a Global Concepts Enterprise, Inc. employee
• This scholarship is potentially renewable and supports one student at a time.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Esther Sheehy McShurley Scholarship Fund

For Esther Sheehy McShurley, giving back has always meant investing in young lives. Whether volunteering at the Boys and Girls Club of Port Salerno or raising funds through its annual events, Esther has seen firsthand how early support can change a child’s path.

“It provides a wonderful start for the boys and girls,” she says. “If we can get to children while they’re young, they can become better citizens when they get older.”

Wanting to extend her impact beyond today, Esther created the Esther Sheehy McShurley Scholarship Fund through a charitable remainder unitrust with the Community Foundation for Palm Beach and Martin Counties. The scholarship will help graduating seniors from Martin County high schools, with a preference for students pursuing vocational or technical education.

She hopes the fund will empower students who are ready to learn skills, launch careers, and build better futures — especially those who dream of starting their own businesses. “There is a great need for scholarships for young people who want to apply their knowledge directly to making a living,” she says.

Esther sees her scholarship as an extension of the work she loves most: encouraging young people to believe in their potential and take their first steps toward independence.

“This is my legacy,” she says. “It’s nice to know that the children who receive this scholarship will know who I am and what I cared about. It’s a good feeling to know that someone will have an opportunity to make something of themselves — and make this a better world.”

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Franz Family Scholarship for Families Impacted by Cancer

• Graduating senior who attends public, private, or home school in the primary service area of the Community Foundation
• Accepted into a 2 or 4-year degree program at an accredited post-secondary school (including vocational/technical school) within the United States
• Financial need, a consideration (encouraged to submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• A cancer patient or survivor; or a sibling or child of a cancer patient, survivor, or victim

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Franz Family International Adoption Scholarship

• Graduating senior who attends public, private, or home school in the primary service area of the Community Foundation
• Accepted into a 2 or 4-year degree program at an accredited post-secondary school (including vocational/technical school) within the United States
• Financial need, a consideration (encouraged to submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• From a family with an internationally adopted child or children (applicants do not have to be adopted themselves but must have at least one sibling who is internationally adopted)

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

REU Powering Redding’s Future Scholarship Fund

Redding Electric Utility (REU) is proud to offer students in the Redding community awards from the REU Powering Redding’s Future Scholarship, Program. The purpose of REU’s Program is to identify and support local students dreaming and planning to attend community college, a 4-year college/university, or technical school. The primary goals of REU’s Powering Redding’s Future program is to encourage Redding’s youth to consider a college/university or technical school education that may lead to career opportunities in the electric utility industry, preferably with REU. This program will award up to $50,000 in scholarships for local students each year.

All REU scholarships are offered to Redding residents.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

REU Powering Redding’s Future Scholarship Fund

Redding Electric Utility (REU) is proud to offer students in the Redding community awards from the REU Powering Redding’s Future Scholarship, Program. The purpose of REU’s Program is to identify and support local students dreaming and planning to attend community college, a 4-year college/university, or technical school. The primary goals of REU’s Powering Redding’s Future program is to encourage Redding’s youth to consider a college/university or technical school education that may lead to career opportunities in the electric utility industry, preferably with REU. This program will award up to $50,000 in scholarships for local students each year.

All REU scholarships are offered to Redding residents.

The BECU Foundation Scholarship aims to support educational endeavors while promoting community service. This scholarship, valued at up to $5,000 over two years, is designed for BECU members who exemplify the philosophy of 'people helping people.' Eligible applicants include high school seniors and current college students with a minimum GPA of 2.5, who are committed to full-time education and community involvement. Apply to join a legacy of giving back while pursuing your academic goals.

Each year, Innovia awards over $500,000 in scholarships to deserving students like you who are college-bound or pursuing vocational or technical training. Single scholarship awards range between $500 and $10,000.

Eilleen Hutchison Scholarship

Primary factors for consideration are academic achievement, financial need and good personal character. Previous recipients of this award are eligible to reapply.