Best Private Grants for Nonprofits in South Dakota

The Alzheimer’s Foundation of America Bi-Annual Grant aims to support nonprofit organizations in their efforts to enhance the lives of individuals impacted by Alzheimer’s disease and related dementias. Each grant, valued at $6,000, is awarded twice a year, focusing on innovative programs and services. AFA emphasizes partnership and collaboration, enabling grantees to manage their own policies and programs while adhering to specific funding guidelines. This initiative underscores AFA's commitment to compassionate care and ethical standards.

The RFA: Biology to Prevention Award (CRUK) aims to foster innovative translational research that enhances understanding of cancer biology, ultimately leading to effective prevention strategies. Joint applications from UK and US research teams are encouraged, with a focus on equal partnerships and complementary expertise. The funding provides up to £600,000 for UK costs and up to $946,000 for US costs, supporting projects of 1 to 5 years duration that address critical research questions in cancer prevention.

The MBF Small Grants Program supports conservation projects for monarch butterflies and their habitats, primarily in Mexico. It aims to fund initiatives focusing on habitat conservation, scientific research, education, and sustainable development. Grants are primarily awarded to Mexican organizations and individuals, with a preference for those with relevant experience. Projects should enhance local livelihoods and promote environmental awareness within the Monarch Butterfly Biosphere Reserve.

The Global Down Syndrome Foundation's Education Awards support innovative educational programs aimed at enhancing the lives of individuals with Down syndrome. This initiative encourages applications for workshops, conferences, and webinars focused on research and medical advancements. Eligible applicants must be members of the foundation or recognized 501(c)(3) organizations, ensuring impactful contributions that benefit the Down syndrome community. With no funding limits for consecutive years, this program promotes significant educational outreach and advocacy.

The APSF/FAER Mentored Research Training Grant aims to enhance anesthesia patient safety by funding promising anesthesiologists who are within 10 years of their first faculty appointment. This two-year grant, totaling $300,000, supports the development of independent researchers focused on perioperative safety. Recipients must allocate 60% of their time to research and career development. With this initiative, the APSF and FAER seek to cultivate the next generation of safety scientists in anesthesia.

The Investigator Initiated Research (IIR) Grants program by the Anesthesia Patient Safety Foundation aims to enhance patient safety in anesthesia care through innovative research. Grants up to $200,000 (or $300,000 with waiver) are available for projects addressing critical safety issues, with a focus on studies leading to measurable improvements in outcomes. The program encourages collaboration and creativity, prioritizing research that lacks alternative funding sources, while also supporting junior investigators with mentorship opportunities.

The Quality Improvement Awards, sponsored by the Anesthesia Patient Safety Foundation (APSF), aim to enhance patient safety during anesthesia care. This initiative invites current trainees and recent graduates to showcase their quality improvement projects. Winners will receive sponsorship to attend the Stoelting Conference in Massachusetts, where they will present their work. The APSF is committed to promoting a culture of safety and learning in anesthesia, ensuring that no one is harmed by anesthesia care.

The American Society for Theatre Research (ASTR) Sally Banes Publication Prize celebrates outstanding publications that explore the relationship between theatre and dance. This award alternates between recognizing books and essays based on even and odd years, respectively. Eligible works must have been published within the last two years. The award includes a $500 prize and free conference registration, encouraging scholarly contributions to the field.

The American Diabetes Association's Postdoctoral Fellowship Awards aim to foster emerging leaders in diabetes research. With a focus on innovative research, these fellowships provide up to three years of funding, including a stipend and allowances. Eligible applicants must hold a recent advanced degree and conduct research at U.S. affiliated institutions. This initiative not only supports career development but also contributes significantly to the mission of preventing and curing diabetes.

The Young Investigator Grant from Alex's Lemonade Stand Foundation supports early career researchers in pediatric oncology. This grant, offering up to $50,000 per year for three years, aims to cultivate promising researchers and encourage innovative research ideas. With a commitment to changing the lives of children with cancer, ALSF plays a crucial role in funding impactful research and empowering the next generation of scientists dedicated to this vital cause.

The Early Career Research Programs: 'A' Award Grant by Alex's Lemonade Stand Foundation aims to support promising early career scientists in pediatric oncology. This grant fosters innovation in childhood cancer research by funding original projects that are not currently financed. Applicants must demonstrate a commitment to pediatric cancer investigation and provide a solid career development plan with mentorship. The funding can reach up to $800,000 over four years, with a maximum of $200,000 available annually.

The Society of Toxicology offers the Supplemental Training for Education Program (STEP), which provides up to $1,000 to support graduate students in toxicology seeking additional training to address skill gaps. Eligible applicants must be PhD students who have completed coursework and passed comprehensive exams. The funding covers workshops or courses not available through their graduate program, enhancing career prospects in toxicology.

The Harry and Myrtle Nabstedt Scholarship, offered by the Quad Cities Community Foundation, supports students from Scott County, Iowa, pursuing post-secondary education at accredited institutions. With a maximum award of $8,000 per year, this need-based scholarship is renewable for up to five years, contingent on maintaining eligibility. Applicants must demonstrate financial need and a minimum GPA of 2.00, showcasing merit through community involvement and other activities.

The Eastern Iowa Angus Association Oliver Hansen Memorial Scholarship, administered by the Quad Cities Community Foundation, supports students from specified Iowa counties pursuing education in agriculture. Applicants must be involved with the Angus breed, maintain a minimum 2.0 GPA, and enroll full-time at accredited institutions. Scholarships provide up to $1,000 annually and are renewable for two years, aiding students in achieving their academic and career goals.

The AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award provides $100,000 annually for three years to early-career faculty dedicated to gastric cancer research. Eligible candidates must have an MD, PhD, or equivalent and a full-time faculty position in North America. The award supports research in various areas related to gastric cancer, ensuring a minimum of 50% time commitment to the project, thus fostering independent careers in digestive diseases.

The Drs. James and Wanda Trefil Science Scholarship, offered by the Kosciuszko Foundation, supports undergraduate students majoring in natural sciences such as physics, biology, and chemistry. This competitive scholarship awards $5,000 and is available to U.S. citizens of Polish descent who maintain a GPA of 3.5 or higher. Applicants must be full-time students and can only receive the scholarship once, with a deadline for letters of recommendation set for March 3, 2026.

The AE Foundation Community Grants aim to support US and Canadian non-profit organizations focused on enhancing the mental health and well-being of young people. By funding local programs, the AE Foundation empowers teens and young adults to embrace authenticity and build a brighter future. Eligible organizations must be certified 501(c)3 non-profits or registered charities, and grant funding should be utilized within 365 days of receipt. This initiative reinforces the importance of mental health in today's society.

The Monticello College Foundation Grant supports projects that promote female education. Eligible applicants include professional educational associations and accredited colleges in the Midwest. The foundation prioritizes innovative proposals that demonstrate significant need. Grants are given for a single fiscal year, with ongoing requests requiring annual re-application. Proposals should be submitted by August 31 for fall consideration and by February 28 for spring review. Funding is not available for direct grants to individuals or capital purposes.

The Minnesota STEM and Youth Leadership Grants, offered by the H.B. Fuller Company Foundation, focus on empowering young individuals through STEM education and leadership development. These grants are intended for tax-exempt organizations that serve communities near H.B. Fuller facilities, aiming to address racial inequities in education and employment. The initiative underscores the company's commitment to community support and creating opportunities for youth to thrive in science, technology, engineering, and mathematics fields.

The Christina Sue Lilja Resource Grants support agricultural literacy by providing funds for educators to purchase resources from the Ag Foundation store. In 2025, 100 educators will receive $100 in store credits, selected randomly if applications exceed this number. This initiative, backed by the CSL Foundation, honors Christy Lilja's legacy of advocating for agricultural education. The grants aim to enhance classroom resources and improve students' understanding of agriculture, ensuring access to accurate information.

The Judith Blumsack Scholarship, offered by the American Academy of Audiology Foundation, awards $500 to a full-time graduate student in audiology who demonstrates exceptional clinical skills and commitment to clinical research and community service. Established in honor of Dr. Judith Blumsack upon her retirement, this scholarship acknowledges her significant contributions to the field and aims to inspire future audiologists to excel in their professional journey.

The Search Team Grant, established by the National Disaster Search Dog Foundation, provides financial assistance to active handlers of live-find and human remains detection canines. This program helps cover out-of-pocket expenses for training and equipment, enabling handlers to remain deployment-ready. Over 17 years, it has supported specialized training and essential gear purchases, ensuring that canine teams can effectively assist communities in need during emergencies.

The National Multiple Sclerosis Society offers the Sylvia Lawry Physician Fellowships to support MDs in acquiring essential clinical trial training. This fellowship aims to enhance expertise in conducting complex trials for MS therapies, fostering skills in protocol design, patient recruitment, and data analysis. Applicants must have relevant medical training and be engaged in ongoing MS clinical research. The program is vital for addressing the increasing demand for trained professionals in MS clinical trials, contributing to advancements in treatment.

The Brees Dream Foundation Grant aims to enhance the lives of cancer patients while providing essential care, education, and opportunities for children and families in need. With the support of generous donors and partners, the Foundation is dedicated to advancing cancer research and offering vital resources to those facing challenges. This commitment reflects a profound dedication to improving quality of life and fostering hope in communities.

The K–12 Educators Grants in American Music, offered by the American Musicological Society, provides $500 awards to K-12 educators with an interest in American music to attend the Teaching Music History Conference. This grant supports educators in engaging with historical pedagogy through workshops and networking opportunities. Participants will explore American music's significance while developing actionable lesson plans, fostering connections among educators and researchers committed to enhancing music education.

The Jacques Pepin Foundation (JPF) is dedicated to advancing culinary arts education by supporting community kitchens that provide culinary training to individuals facing employment barriers. Grants of up to $10,000 are available for nonprofits to enhance their culinary programs, including operating costs and facility improvements. Eligibility extends to organizations funded in prior cycles, those that applied but were not funded, and newcomers to JPF funding. This initiative aims to empower underserved communities through culinary skills.

The AGA: Caroline Craig Augustyn & Damian Augustyn Award in Digestive Cancer offers $40,000 for one year to early career investigators holding a career development award focused on digestive cancer research. This grant aims to support innovative studies in pathogenesis, prevention, diagnosis, and treatment. Applicants must provide evidence of their current awards, a recommendation letter, and demonstrate how the AGA funding will facilitate their transition to independence in research.