Best Private Grants for Nonprofits in South Dakota

The Peter S. Slomianyj Scholarship Fund offers financial assistance to Subway employees and their children who meet specific eligibility criteria, including a minimum of 500 work hours over the past year and a GPA of 2.0 in high school or 2.5 in college. Applications for this scholarship will be open from December 16, 2025, to March 3, 2026. It is part of a broader initiative by the North Carolina Community Foundation to support students pursuing education at various institutions.

The Leukemia & Lymphoma Society's Equity in Access Research Grants aim to enhance equitable access to care for blood cancer patients and survivors. This program funds research to identify effective interventions that increase participation in clinical trials among underrepresented groups. Projects can receive up to $500,000 annually for a maximum of five years, with a total budget cap of $2.5 million. The initiative seeks to address systemic barriers that hinder clinical trial enrollment and improve healthcare access.

The Sam J. Lucas Jr. Scholarship, administered by the Greater Houston Community Foundation, offers multiple awards of $5,000 for employees and dependents of SCI Shared Resources, LLC. This one-time award is intended for students pursuing higher education in accredited institutions and requires a minimum GPA of 2.5. Recipients must be enrolled in at least 6 credit hours and submit enrollment information to facilitate the scholarship's direct payment to their college.

The Southwest Airlines® Community Scholarship, administered by the Greater Houston Community Foundation, offers ten annual scholarships of up to $20,000 for students pursuing higher education in the airline industry. Eligible applicants must demonstrate a career interest in this field, maintain a minimum GPA of 3.5, and be 24 or younger. This renewable scholarship supports students attending accredited institutions and is specifically for those seeking their first post-secondary degree. Dependents of Southwest Airlines employees are not eligible.

The Southwest Airlines® Founders Scholarship, administered by the Greater Houston Community Foundation, offers financial support to dependents of Southwest Airlines employees pursuing their first post-secondary degree. Established in 1981, this renewable scholarship awards up to $20,000 over four years, contingent on meeting GPA and enrollment criteria. Eligible applicants must demonstrate community service and maintain a minimum GPA of 3.5. This scholarship underscores the commitment to empowering educated communities.

Multiple Sclerosis Foundation

The Multiple Sclerosis Foundation, known in the MS community as MS Focus, is a nonprofit organization focused on providing free services that address the critical needs of people with MS and their families, helping them maintain the best quality of life. 

The symptoms of MS are unpredictable and may increase in severity over time. This presents physical, emotional, and financial challenges families must face. MS Focus is here to provide the support, education, and assistance needed to adapt to these challenging circumstances. Our primary focus is on providing individuals with MS the help they need to maintain their health and well-being, to continue to be productive and independent, and to keep a roof over their heads and a safe environment in their home. We do so with empathy, resourcefulness, and conscientious care.

Whom does MS Focus serve?

Our resources assist people who have MS, their families and caregivers, regional support groups, and healthcare professionals. Our programs and grants are available in the 50 U.S. states and Puerto Rico. Online resources, such as our educational materials or audio programs, are available throughout the world.

Assistive Technology Program

The Assistive Technology (AT) Program may help locate, partially fund, or provide full funding for one of a wide range of devices. These allow those with MS to function more independently in their daily lives, as well as more easily participate in recreational, educational, and vocational activities. These include:

• Aids for daily living
• Communication devices
• Computer aids
• Environmental control systems
• Home and vehicle modifications
• Orthotics
• Seating, positioning, and mobility devices
• Aids for vision and hearing
• Cooling aids

The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.

The Innovation Grants to Nurture Initial Translational Efforts (IGNITE) support the development of assays and screening processes to identify potential therapeutic agents for neurological disorders and non-opioid analgesics. Sponsored by the NIH, this initiative seeks to foster collaborations and projects that utilize innovative methodologies. Although applications are not currently being solicited, interested parties are encouraged to prepare meaningful proposals that align with the goals of the NIH Helping to End Addiction Long Term initiative.

The RAK Education Foundation Scholarship provides financial assistance to residents of Camden, Chowan, Gates, Pasquotank, or Perquimans Counties who have earned a high school diploma or GED. This scholarship supports students pursuing degrees or certificates in Career and Technical Education fields such as trade education, computer science, business, health science, and more. Applications open on December 16, 2025, and close on March 3, 2026, encouraging eligible students to apply.

The Marie Darlin Prize, administered by the Juneau-Douglas City Museum and overseen by the Juneau Community Foundation, honors exceptional artistic and scholarly works that reflect Southeast Alaska's cultural heritage. Awarded annually, the prize of $5,000 recognizes individuals or collaborations committed to the region's social and cultural history, community advocacy, and Indigenous identity. Eligible applicants include writers, visual artists, and performers who have produced significant works within the last five years.

The Virginia Randolph Scholarship, established in 1963, honors the legacy of a pioneering educator in Henrico County. Managed by The Community Foundation for a Greater Richmond, this scholarship supports graduating high school seniors who demonstrate academic promise, community service, and financial need. It ensures a lasting tribute to Virginia Randolph’s commitment to education and helps empower the next generation of leaders in the region. Eligible students can receive tuition assistance for higher education pursuits.

Community Foundation of Northwest Mississippi

The Community Foundation of Northwest Mississippi manages 314 donor-established funds and has disbursed over $48 million to support more than 1,000 charitable organizations and activities recommended by its donors, as well as charitable programs established by the foundation. Established in 2002 with a generous grant from the Maddox Foundation, the Community Foundation is an independent 501(c)3 charitable organization. The Foundation serves Bolivar, Coahoma, DeSoto, Leflore, Marshall, Panola, Quitman, Sunflower, Tallahatchie, Tate, Tunica and Yalobusha counties. 

The Reese and Joelle Norris Service through Music Scholarship

The Community Foundation, CoroRio, and MidSouth Music Institute is pleased to offer a $500 college scholarship: The Reese and Joelle Norris Service through Music Scholarship. We are grateful to Reese and Joelle Norris for more than ten years of service to CoroRio and the MidSouth Music Institute. Together, they have nearly 50 years of teaching thousands of all ages throughout the MidSouth and across the country.

Starting in the Spring of 2024, the scholarship will be awarded each year to a student who is currently involved in CoroRio, plans to pursue a career related to music, and has demonstrated a passion for serving others through music, like Reese and Joelle. 

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) invites applications for mid-phase clinical trials involving natural products like botanicals and dietary supplements. The goal is to advance clinical testing through robust preliminary data, ensuring these products demonstrate measurable impacts on target engagement. Submission deadlines span from March 2024 to October 2026. Applications must focus on optimizing doses and identifying patient responders to inform future efficacy trials, aligning with NCCIH's research priorities.

The HVAC Skills Lab Grant aims to support middle and high schools in the U.S. and Canada by providing equipment and resources to establish plumbing and HVAC skills labs. With a growing demand for skilled trades, this program encourages educational institutions to equip students with vital trade skills. Grant recipients will receive $25,000 worth of products and equipment, along with access to SkillCat's technical training platform, fostering a new generation of skilled professionals.

The HVAC Skills Lab Grant aims to refurbish existing plumbing and HVAC skills labs in middle and high schools across the U.S. and Canada. With a focus on preparing students for vital trade careers, the grant provides $10,000 in equipment to enhance hands-on learning. This initiative supports schools with technical training resources, promoting the growth of skilled labor in these essential fields. Schools that have not received a Skills Lab award in the past 24 months are eligible to apply.

The NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) promotes innovative clinical trials on natural products, such as botanicals and dietary supplements. This funding opportunity supports studies that demonstrate significant scientific rationale and preliminary evidence for efficacy. Applications can explore various delivery methods and combinations with existing treatments to enhance outcomes. Funding is available for up to three years, aimed at bridging basic science discoveries into practical clinical applications.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award supports investigator-initiated clinical trials of natural products, including botanicals and dietary supplements. This funding opportunity aims to validate the pharmacokinetics and bioavailability of these products over three years in a phased approach. Successful trials will provide crucial data for further development and clinical application, emphasizing the importance of scientifically driven research in natural product efficacy.

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Siletz Scholarship

This scholarship is open to any field of study.

The Yass Prize & STOP Awards Initiative aims to revolutionize education by recognizing and supporting exceptional education providers focused on Sustainable, Transformational, Outstanding, and Permissionless (STOP) education. Established in 2021, the initiative awards funds to organizations serving Pre-K to 12th grade students across the United States, fostering impactful partnerships and innovative practices. With a commitment to transforming educational experiences, the initiative celebrates the vital work of educators in response to contemporary challenges.

The Multiple Sclerosis Clinical Care Physician Fellowship is a one-year program by the National Multiple Sclerosis Society aimed at training neurologists and physiatrists in specialized clinical care for MS patients. Eligible candidates include PGY3 or PGY4 residents from U.S. programs. The fellowship focuses on supervised patient care, multidisciplinary team activities, and professional development, preparing fellows to provide high-quality care and to engage as future leaders in the MS community.

The National MS Society's Institutional Clinician Training Award supports the training of neurologists and physiatrists in comprehensive MS care. This program enhances the skills of postdoctoral fellows through mentorship and specialized training, ensuring they are equipped to provide personalized, high-quality care. The Society aims to foster a community of leaders in MS clinical practice, encouraging active participation in research and volunteer opportunities to improve outcomes for individuals with MS.

The Tommy Aaron/Charlie Aaron Foundation Scholarship, managed by the North Georgia Community Foundation, supports graduating seniors from Hall County or Gainesville City public schools and Lakeview Academy. This $10,000 scholarship, distributed over four years, promotes academic achievement and integrity through golf. Eligible applicants must have a minimum GPA of 2.5, demonstrate financial need, and exhibit strong character traits. This initiative aims to empower local students to pursue higher education while honoring the values of sportsmanship and respect.

The NIA Academic Leadership Career Award (K07) provides funding for established investigators to strengthen research capacity in aging and Alzheimer's Disease. The program supports the development of educational infrastructure, mentorship, and career development activities. Key deadlines for applications include February 12, June 12, and October 12 from 2025 to 2027. This award is specifically for research not involving independent clinical trials, allowing applicants to gain experience in trials led by others.

Achievement Scholarship for Students with a History of Chronic Illness (FN)

Essay:

• Tell us about your experiences/struggles with your chronic illness and what you have done to overcome it.

Awards:

• One time award of $1,500.

The Vadon Foundation Grant supports innovative, community-based initiatives aimed at sustaining healthy indigenous nations. By empowering visionary changemakers, the foundation addresses multi-generational challenges through focused programming in areas like language revitalization, community leadership, and addressing crises such as food insecurity. The foundation seeks to foster self-determination and sustainability within native communities, ensuring that future generations can thrive culturally and socially.

The NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional) aims to foster innovative research career development for clinically trained vision scientists. This funding opportunity encourages institutions to develop programs that prepare scholars for independent research careers, particularly in minimal risk clinical trials. Emphasis is placed on recruiting underrepresented groups in research, ensuring a diverse pool of clinician investigators engaged in vision research.

The NewSchools Learning Differences Grant Program aims to enhance educational opportunities for students who learn differently, particularly those affected by poverty and racism. The program invests in innovative solutions and models that support personalized education for these students, ensuring they have access to quality instruction and belonging within school communities. With a focus on equity, it seeks ideas that align with its core investment areas and addresses the needs of marginalized learners.