Best Large Grants for Nonprofit Organizations in Tennessee

The Air Force Fiscal Year 2027 Young Investigator Program (YIP) is designed to support early career scientists and engineers who have recently obtained their Ph.D. This initiative aims to promote innovative basic research in science and engineering while enhancing the professional growth of promising investigators. Awards are available to U.S. institutions where the principal investigator is a full-time employee. Eligible candidates must be U.S. citizens, nationals, or permanent residents.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Jessica Joelle Holt and Emmy Macfarlane Memorial Scholarship

Open to graduating seniors from Pitman, Turlock, and Denair High Schools pursuing a career in teaching.

Award Amount:

• $1,000

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Peter and Huberdina Weller Scholarship

• Graduating senior, graduating early college student, or current college student from a high school within the greater Community Foundation service area
• Enrolling/enrolled at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Intention to pursue educational opportunities and a career in horticulture or the biological sciences with an emphasis on botany
• All other qualifications being equal, tie-breaking consideration will be given to students of color
• Previous recipients of the award are encouraged to reapply.

The Burton and Erma Lewis Structural Engineering Scholarship, established by the estate of Mr. Lewis in 2025, aims to support students pursuing degrees in structural engineering. Awarded annually, the scholarship is available to undergraduate students enrolled in ABET-accredited programs who demonstrate a commitment to the field. Recipients can use the funds for tuition and academic fees, facilitating their education and career development in civil engineering.

The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.

The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.

The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.

The Edward C. Roy Jr. Award for Excellence in K-8 Earth Science Teaching, established by the American Geosciences Institute, honors educators who demonstrate exceptional leadership in earth science education. This prestigious award includes a $2500 prize for the winning teacher and a $1500 grant to attend the National Science Teaching Association's annual conference. The award celebrates the legacy of Dr. Edward C. Roy Jr., promoting innovation and excellence in teaching for future generations.

TE Connectivity's Community Ambassador Program supports meaningful community impact by providing grants to registered nonprofits and educational institutions. This initiative evaluates proposals based on alignment with TE's values, community focus areas like education or health services, and opportunities for employee engagement. The program operates both in the US and internationally, with numerous ambassador locations, aiming to foster community development and engagement around the globe.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Bob Boggeri Farms Fund

Open to students planning to pursue a degree in Ag or Horticulture. Must be a FFA member and demonstrate financial need. Preference given to students from Hughson.

Award Amount:

• $1,000

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Jeanette Elmer Scholarship

This opportunity is provided to honor the life and legacy of Jeanette Elmer.

The purpose of the Jeanette Elmer Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in library science.

This opportunity is a need-based award.

The Outstanding Earth Science Teacher (OEST) Award recognizes exceptional K-12 educators for their contributions to Earth Science education. Established in 1971 by the National Association of Geoscience Teachers, the award aims to stimulate interest in Earth Sciences among students. Eight national finalists are chosen annually, ensuring broad recognition and encouraging teaching excellence. Nominees can apply themselves or be nominated by colleagues, allowing for two awards in an educator's career to honor both early and late career achievements.

The Civic Experiment Grant by the Trust for Civic Life supports innovative, community-driven projects aimed at enhancing civic engagement. It focuses on rural areas, empowering local leaders to tackle challenges collaboratively. Grants up to $25,000 are available for organizations that are non-partisan and primarily serve rural communities, emphasizing inclusivity and sustainable impact. The next nomination period begins in early 2026, following a closed cycle for 2025. This initiative fosters long-term civic infrastructure and community resilience.

The GoodRx Helps Community Catalyst Grants support community-led nonprofits dedicated to enhancing health and well-being for under-resourced groups. This funding aims to improve healthcare access, education, and essential services, addressing systemic barriers faced by these communities. Eligible organizations must demonstrate a commitment to community empowerment and possess a minimum annual operating budget of $250K. This initiative underscores the importance of fostering sustainable health improvements through targeted, inclusive support.

The Camille Dreyfus Teacher-Scholar Awards Program supports talented early career faculty in the chemical sciences by providing an unrestricted research grant of $100,000. Nominees must demonstrate outstanding research achievements and a commitment to education. Each institution can submit one nomination annually. The program emphasizes innovation and leadership in research while considering factors such as awards, publication success, and contributions to education, particularly at the undergraduate level.

The Wolcott Family Foundation focuses on funding grassroots organizations that drive social change and environmental stewardship. They prioritize support for projects that empower communities, strengthen civil liberties, and address ecological challenges. Eligible applicants are nonprofit organizations in Colorado classified under section 501(c)(3), with grants awarded for one year. The foundation values projects emphasizing environmental preservation and community involvement aimed at tackling societal issues.

The ASTRO-AAPM Physics Resident/Post-Doctoral Fellow Seed Grant supports early-career scientists in radiation oncology physics research. Jointly funded by AAPM and ASTRO, this grant aims to foster innovation in the field, with up to two awards of $50,000 each available. Eligible applicants include medical physics residents and post-doctoral fellows who are active members of ASTRO and AAPM. This initiative strives to enhance the next generation of researchers, ensuring a commitment to advancing radiation oncology.

The AOAP Swim Lesson Grant aims to enhance drowning prevention by providing financial support to aquatic facilities for swim lessons and life jackets. With a minimum allocation of $10,000 annually, the program seeks to offer at least 100 free lessons to low-income participants and distribute 500 life jackets each year. It encourages non-profit organizations to apply, ensuring a focus on education and safety in aquatic environments. This grant represents a significant step towards making swimming accessible and safe for all.

The ACS-Hach High School Chemistry Classroom Grant aims to enhance chemistry education by providing funding for innovative teaching ideas. Since its inception in 2008, over 700 teachers have benefited from grants of up to $1,800. Eligible applicants are U.S. high school chemistry educators, and the funding can be used for laboratory supplies, instructional materials, professional development, and student-led field studies, fostering a deeper understanding of chemistry.

The Ray Y Gildea Jr Award, provided by the Royal Geographical Society, offers grants of up to £1,000 to support innovative teaching methods in higher and secondary education. This endowed award aims to enhance geography education by funding projects that develop, research, or pilot new approaches, ultimately benefiting students directly. Eligible applicants must be actively teaching in the higher education or secondary school sectors in the UK or USA.

The CFA Ministry Grants Initiative, part of the Kentucky Conference's mission, supports local churches in developing ministries focused on stewardship, technology, and leadership development. Eligible churches can apply for grants up to $500, with each church allowed to submit two applications annually. This initiative aims to foster generosity and enhance church leadership, providing essential resources to help congregations grow and effectively fulfill their mission of making disciples of Jesus Christ.

The Brice and Teresa Moczygemba Engineering Scholarship Fund, established by the San Antonio Area Foundation, supports students pursuing a Bachelor's degree in Civil Engineering from accredited programs in the U.S. Eligible applicants include current high school seniors and college students residing in Bexar, Karnes, or Wilson counties, with a minimum GPA of 3.6. This renewable scholarship covers tuition, fees, books, and educational expenses, reinforcing the Foundation's commitment to enhancing community well-being.

Communities Foundation of Oklahoma

The Communities Foundation of Oklahoma stems from the vision of Tom McCasland Jr., and Gene Rainbolt. Two decades ago, these gentlemen formed a shared vision to create a single philanthropic organization to serve the charitable needs to rural communities across the great state of Oklahoma. Today, CFO has grown to assist hundreds of efforts in more than 45 counties.

Scholarship Opportunities

CFO offers over 100 diverse scholarship opportunities, empowering students across the state to pursue their educational goals. Each scholarship is tailored to meet unique needs, making higher education more accessible for all.

Ashley Parks Creative Scholarship

Supports continued education in the arts or creative fields for non-traditional students.

The DOJ FY 2026 ANGEL Grant Program aims to enhance public safety by funding state, local, and tribal government initiatives to combat violent crime committed by criminal illegal aliens. This program supports hiring law enforcement personnel, retaining critical staff, and acquiring advanced technology. The objective is to prevent harm to American citizens and support Homeland Security Task Force operations. Applications must be submitted by October 27, 2026, to qualify for funding.

The NABG Scholarships support full-time undergraduate and graduate students in Geoscience programs at accredited institutions, with over $300,000 in funding raised through donations and events. Candidates must exhibit academic excellence, aiming to equip them for future careers in the geosciences. This initiative, backed by the National Association of Black Geoscientists, fosters diversity and prepares the next generation of professionals in the field.

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.