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Best Large Grants for Nonprofit Organizations in Tennessee

Find the perfect Large Grants for Nonprofit Organizations in Tennessee on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Tennessee in the United States.

9,000+

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$2.55B

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$5K

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9,000+ grants
$2.55B total
$5K median

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9,430 Results based on applied filters

The Applied Materials Momentum Fund - Bridge Grants

Applied Materials Foundation
Corporate
United States
Approximately US $1,100
The Applied Materials Momentum Fund - Bridge Grants aim to support students facing financial obstacles in completing their computing degrees. This initiative fosters diversity in the semiconductor industry by encouraging women engineers and providing them with career-building opportunities. Eligible candidates include U.S. citizens, DACA recipients, and F1 visa holders pursuing engineering majors. The fund not only alleviates financial stress but also opens doors to internships and full-time positions at Applied Materials, thus enhancing educational progress and career advancement.
Science Communications Physics Bioengineering +10 more

The Applied Materials Momentum Fund - Emergency Financial Assistance

Applied Materials Foundation
Corporate
United States
Up to US $595
The Applied Materials Momentum Fund offers emergency financial assistance to students facing unexpected financial obstacles while pursuing degrees in engineering. This initiative supports basic needs such as food, housing, and transportation, ensuring that students can continue their education without interruption. It aims to empower women engineers and underrepresented groups in the semiconductor industry, fostering a diverse and resilient workforce for the future.
Aerospace Engineering Chemical Engineering Computer Science & Engineering +10 more

Union Home Foundation Grant

The Union Home Foundation Inc
Private
Ada County, Idaho, Aiken County, South Carolina +183 more
More than US $1,000
The Union Home Foundation Grant provides financial support to nonprofit organizations that promote economic self-sufficiency through financial literacy and housing initiatives. Established in 2015, this grant has awarded over $2 million to various nonprofits across the U.S. Grants typically start at $1,000 and are available for a one-year period. Organizations must be 501(c)(3) tax-exempt and can only apply once per year, following specific eligibility criteria.
Financial Literacy Equitable & Affordable Housing Supportive Housing & Shelters

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative: Pain Research Enhancement Program (PREP) supports R15-eligible Principal Investigators in conducting innovative pain research. This program encourages interdisciplinary partnerships and aims to enhance the research environment for health professional trainees. Key application deadlines include November 19, 2024, and October 28, 2025, with specific dates for AIDS-related applications. By fostering collaboration, the initiative seeks to advance understanding and treatment of pain.
Chronic / Acute Pain Drug Use Disorder Anesthesia and Pain Medicine

Kalamazoo Valley Chapter - George L. Disborough TU Research Grant Fund

Trout Unlimited, Inc.
Private
Caribbean, Mexico +1 more
Up to US $2,500
The Kalamazoo Valley Chapter's George L. Disborough TU Research Grant Fund, established in 1990, aims to support graduate-level research on trout habitat and conservation projects aligned with Trout Unlimited's mission. This fund seeks innovative studies on coldwater salmonids and their environments, with a preference for projects conducted in Michigan. It is open to U.S. citizens or permanent residents enrolled in accredited institutions, promoting efforts that enhance the quality of aquatic resources.
Ichthyology (Fish) Fisheries Freshwater Conservation

Richard and Mary Myerly Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Richard and Mary Myerly Scholarship, offered by the Community Foundation of Washington County, MD, supports low-income students pursuing careers in photography or fine arts at accredited institutions. Established in memory of Richard and Mary Myerly, this scholarship invites applications from students in Washington County and surrounding areas, promoting educational opportunities and honoring community values. With over 100 scholarships available, this initiative aims to empower the next generation of artists and photographers.
Education - Higher Education Education - High School Academic Scholarship Programs +4 more

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

Biogen General Grants

Biogen Foundation Inc.
Corporate
United States
Unspecified amount

Biogen General Grants

Funding to support a project or program that does not fit any of the other defined grant categories.

Biosimilars Neurological Diseases & Disorders Musculoskeletal Diseases +2 more

Kaiser Permanente Center for Gun Violence Research and Education Grant Program

Kaiser Permanente Advisory Services
Private
United States
Up to US $300,000
The Kaiser Permanente Center for Gun Violence Research and Education Grant Program aims to transform the landscape of gun violence research and education by funding initiatives that address community firearm violence and suicide. This program focuses on partnering with affected communities, integrating healthcare approaches, and providing substantial funding to enhance research capacity and intervention effectiveness. With funding available in two categories, the initiative seeks to promote evidence-based solutions that foster community healing and well-being.
Gun Violence Prevention Suicide Prevention

Healthy American Forests Initiative

National Fish and Wildlife Foundation (NFWF)
Private
Puerto Rico, United States +1 more
US $250,000 - US $2,000,000
The Healthy American Forests Initiative, led by the National Fish and Wildlife Foundation (NFWF), aims to enhance forest health and resilience through targeted funding. This initiative anticipates awarding 10-15 grants ranging from $250,000 to $2 million, supporting projects up to 2 years in duration. A 20% non-federal match is required, and interested applicants are encouraged to collaborate with NFWF and Native Americans in Philanthropy for potential match funding.
Environmental Conservation Water Resource Management

Lasher-Bottorff Award

American Association of Avian Pathologists
Association/Society
North America
US $1,000
The Lasher-Bottorff Award, established by the American Association of Avian Pathologists, recognizes outstanding contributions to poultry health. It honors Dr. Hiram N. Lasher and Dr. C. A. Bottorff, pivotal figures in avian medicine. The award, valued at $1,000, is presented annually to a veterinarian who has made significant advancements in avian diagnostics or technical services over the past decade, promoting the health and productivity of poultry in North America.
Ornithology Veterinary Science & Services Diseases & Conditions

SAF National Awards Program: W. D. Hagenstein Communicator Award

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The W. D. Hagenstein Communicator Award honors an SAF member for their outstanding communication efforts in forestry. Recognizing innovative initiatives that enhance public understanding of forestry and natural resources, this award is presented at the SAF National Convention. It includes a $500 honorarium and up to $500 for travel expenses. Nominees must be SAF members and should not have received the Technology Transfer Award in the past five years. This award emphasizes the importance of effective communication in advancing forestry.
Forestry Science Communications

Ottawa County Community Foundation Grant

Toledo Community Foundation
Private
Ohio, United States
Up to US $5,000

Greater Toledo Community Foundation

Greater Toledo Community Foundation transforms generosity into lasting impact. With over $510 million in assets across 1,000+ funds, we've granted more than $370 million to strengthen education, health, arts, and social services throughout our region.

We connect donors with causes they care about while bringing together leaders, organizations, and resources to tackle our community's biggest challenges. What began with Walter E. Terhune's vision in the 1920s continues today as we help individuals, families, and businesses create positive change that will benefit our region for generations.

Ottawa County Community Foundation Grants

The Ottawa County Community Foundation, Inc. (OCCF) is a public charitable organization created by the citizens of Ottawa County to enrich the quality of life for individuals and families in Ottawa County. Grants from unrestricted funds support a variety of programs in the fields of education, health and social services, economic development, natural resources and the arts.

Educational Access & Equity Health Disparities & Social Determinants of Health Economic Services & Development +2 more

SAF National Awards Program: Sir William Schlich Memorial Award

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The SAF National Awards Program includes the Sir William Schlich Memorial Award, which honors exceptional contributions to forestry, particularly in policy and international activities. Presented biennially at the SAF National Convention, it features a $500 honorarium, complimentary registration, and up to $500 for travel expenses. This award commemorates Sir William Schlich's significant role in advancing forestry education and practices in the 19th century, promoting sustainable management of forest resources.
Forestry Environmental Policy

RFP: Using Real-World Data to Address Prevalence and Treatment of Cardiovascular, Kidney and Metabolic Disease in Cancer Patients and Survivors

American Heart Association
Association/Society
United States
US $150,000
The American Heart Association is seeking proposals to study the prevalence and treatment of cardiovascular, kidney, and metabolic diseases among cancer patients and survivors. Given the over 16.7 million cancer survivors in the U.S., this research aims to highlight critical health disparities, identify treatment modalities, and explore shared risk factors. Applications focusing on underrepresented populations and utilizing real-world data sources are especially encouraged, aiming to improve health outcomes in this vulnerable group.
Cancer / Oncology Cardiovascular Diseases & Systems Kidney Diseases +1 more

John Harsch Regenerative Agriculture Grant

Wright Service Corp Foundation for Sustainability and Innovation
Private
North America
Unspecified amount

Our Mission and Vision

The Wright Foundation for Sustainability and Innovation exists to foster innovative sustainability initiatives that make a positive impact on our planet. We want to find solutions to the complex challenges facing our world today.

Our vision is to facilitate positive action toward sustainable and innovative solutions in agricultural and environmental sectors that reduce carbon footprints and minimize risk for our communities.

Grant Programs

Wright Foundation for Sustainability and Innovation administers projects directly funded by donors that help reduce carbon footprints through carbon positive practices and emission offsetting. The foundation holds open application periods for projects in the contiguous United States, Puerto Rico and Canada that focus on reducing environmental risk through regenerative agricultural practices, habitat restoration and using natural energy sources to make our communities more sustainable.

Reducing Carbon Footprints

The foundation supports projects that work to reduce carbon footprints through the following initiatives.

Habitat Reclamation

  • Restoration of habitats creates spaces for native flora and fauna and microorganisms to survive. Natural landscapes are integral to functioning ecosystems and increasing biodiversity, not to mention creating habitats for pollinator species like bees and butterflies that we so desperately need for agricultural success.

Regenerative Agriculture

  • Regenerative agricultural practices have a far-reaching impact on the industry and our lives. We aim to reduce carbon emissions by fostering projects that innovate row crop sustainability and dairy, beef, pork and poultry operations to create practices that are sustainable for years to come.

Renewable Energy

  • We care about carbon positive practices that harness renewable resources like solar, wind and biomass for improved efficiencies and overall reduction in use. Organic matter often sourced from agricultural production, garbage and tree pruning can be converted to energy in various ways, recycling it back into the agricultural operation that created it or fueling our communities.

Soil

  • Soil sequestering practices have wide-reaching benefits like restoring and building organic matter in the soil and increasing biodiversity. It boosts water infiltration and retention and reduces erosion. Through practices like no till, applying organic matter like manure and biochar, and planting cover crops, we improve soil health as well as take CO2 out of the atmosphere.

Tree Planting

  • Planting trees is a simple act that makes a huge impact in our urban, suburban and rural communities. They provide shade, release oxygen and improve air quality, improve soil quality and biodiversity, all of which contributes to offsetting carbon emissions.  
  • Water
  • We want to find ways to protect and restore the integrity of our water resources. We aim to fund projects focused on practices that create efficiencies and reduce the agricultural production impact on water quality and benefit our communities by conserving one of our most important natural resources. 

John Harsch Regenerative Agriculture Grant

Funding for projects adopting best regenerative agricultural management practices that impact one or several of these areas:

  • Improve water quality
  • Reduce soil erosion
  • Increase soil health index
  • Reduce synthetic fertilizer use
  • Increase effective manure use as a fertilizer
  • Increase biodiversity
  • Reduce methane and nitrous oxide emissions

Carbon / Greenhouse Gas Reduction Sustainable Agriculture & Agroecology

The Dale Jr. Foundation In-Kind Donation

Dale Jr Foundation
Private
United States
Unspecified amount
The Dale Jr. Foundation is dedicated to empowering underprivileged youth through targeted support in five key areas: Empowerment, Education, Wellness, Hunger, and Hope. By providing safe homes, educational resources, and healthy food, the foundation helps children overcome adversity and achieve their dreams. Their commitment extends to various charities, ensuring that every child has the opportunity to thrive. The foundation emphasizes community support and holistic care, making a significant impact in the lives of many young people.
Youth Services Food Access & Hunger Children’s Health & Pediatrics +2 more

National Child Traumatic Stress Initiative - Community Treatment and Service Centers

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Up to US $40,200,000
The National Child Traumatic Stress Initiative aims to enhance trauma-focused treatment and services for children and adolescents affected by traumatic events. By increasing access to these vital services, the initiative seeks to support families in overcoming the challenges posed by trauma. Eligible applicants include public and private nonprofit entities, ensuring a broad reach for effective intervention and support within communities.
Youth Services Family Services Crisis Intervention +1 more

NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) (357995)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) invites proposals for high-risk, multi-center observational studies on diseases relevant to NIDDK's mission. Applicants are encouraged to consult with NIDDK staff and must complete planning activities before submission. Key deadlines for applications span from February 2025 to October 2026, with optional Letters of Intent due 30 days prior to full proposals.
Diabetes Kidney Diseases Digestive System Health & Diseases

J. C. & L. A. Duke Employees' Assistance Fund

The Saint Paul & Minnesota Foundation
Private
United States
Unspecified amount

J. C. & L. A. Duke Employees' Assistance Fund

Grants from the Duke Fund are designed to:

  • Help recipients achieve self-sufficiency and/or return to the workplace.
  • Provide transitional assistance.
  • Improve the quality of life for the employee and their family.

Selection Criteria

The applicant must have experienced a combination of the following factors:

  • Financial hardship as a result of a catastrophic illness or accident.
  • Lack or depletion of benefits available through the 3M Benefit Plan, personal benefit plans and/or other resources.
  • In addition, the applicant must be able to demonstrate that a grant will substantially assist them in overcoming all or a portion of the adversity. Awards will be made without regard to race, creed, color, gender, individual marital status, religion or national origin.
Emergency Medical Care & Services Medication Use & Compliance

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) (357602)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) aim to support clinical trials that can be completed within a limited timeframe. This funding opportunity encourages a variety of exploratory studies that align with the NIAMS mission, focusing on interventions such as drugs, biologics, devices, and various therapies. Applications are due by 5:00 PM local time of the applicant organization.
Musculoskeletal Diseases Neurological Diseases & Disorders Skin Diseases & Dermatology +1 more

Quality Improvement in Molecular Testing Pathways for Metastatic Colorectal Cancer (mCRC)

Pfizer, Inc.
Corporate
United States
US $150,000 - US $250,000

About Pfizer External Research & Grants

Pfizer External Research & Grants (ER&G) supports independent research, education, and QI initiatives to improve patient outcomes in areas of unmet need. Competitive grants are awarded through transparent RFPs reviewed by independent expert panels.

About ASCP

American Society for Clinical Pathology (ASCP) is the world’s largest professional membership organization for pathologists and laboratory professionals, with more than 100,000 members. ASCP provides excellence in education, certification, and advocacy on behalf of patients and the laboratory workforce. With a portfolio of more than 900 educational activities, ASCP is the worldwide leader in providing CME/CMLE credit for the entire laboratory team.

Quality Improvement in Molecular Testing Pathways for Metastatic Colorectal Cancer (mCRC)

The American Society for Clinical Pathology (ASCP), in collaboration with Pfizer Inc. and with participation from the American Society of Clinical Oncology (ASCO, invites proposals for pathology-centric Quality Improvement (QI) initiatives aimed at optimizing molecular testing pathways in the management of metastatic colorectal cancer (mCRC). This grant opportunity seeks to fund sustainable projects that improve biomarker testing practices, strengthen targeted therapy selection, and support care teams in implementing patient-centered protocols. 

The overarching goal of this program is to advance diagnostic excellence and improve treatment decision-making for patients with mCRC.

Cancer / Oncology Colon Cancer

Graduate Education Fund: Specialty Field Scholarships - AUKUS Scholarship

American Australian Association
Private
Australia, United States
Up to US $40,000
The AUKUS Scholarship, part of the Graduate Education Fund, supports American and Australian graduate students in security, technology, and diplomacy fields. Applicants must be citizens or permanent residents, with an offer from an accredited institution. The scholarship provides up to $40,000 for tuition, travel, and living expenses. Applications are due in March for Australia to USA and in September for USA to Australia. This initiative strengthens ties and promotes research in critical areas.
Domestic / Homeland Security Education - Higher Education International / Foreign Affairs +7 more

Stassel Education Scholarship

The Alaska Community Foundation
Private
United States
US $1,000

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Stassel Education Scholarship Fund

The Stassel Fund was established in memory of Fred L. and Jean N. Stassel who came to Alaska on their honeymoon in 1949, making Anchorage their home for over 60 years until they passed away in 2017 and 2011 respectively. Here they raised 6 children, celebrated Alaska's statehood in 1959, survived the 1964 earthquake, and became active in the community and state. The Fund honors their dedication to education and service to others focusing on creating opportunities for all Alaskans, especially the vulnerable and most in need. Fred and Jean valued education, hard work, integrity, justice, respect, and care for all people. They were both educators, commercial fishers, and very active in social services through the United Methodist Church and other organizations. Fred was very influential in establishing the now-named Credit Union 1, and Jean was active with The League of Women Voters. They would be honored to know that deserving Alaskans were able to pursue their educational goals with the help of scholarships from the Stassel Education Fund.

Education - Higher Education STEM / STEAM Education Mathematics +7 more

Unity for Humanity Grant

Unity Technologies
Corporate
Afghanistan, Algeria +83 more
Up to US $500,000
The Unity for Humanity Grant invites innovative creators to submit impact-driven projects that utilize real-time 3D technology. This annual grant provides funding, technical support, and marketing resources to help bring visionary ideas to life. Projects must align with UN Sustainable Development Goals and demonstrate measurable impact. Eligible submissions include prototypes across various genres, fostering a more inclusive and sustainable world. Join us in empowering changemakers to make a positive global difference.
Human & Social Services Environment Health & Medicine +11 more

NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed) (357511)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.
Science Biology Medical Education & Professional Training +3 more

CDV5 Foundation Grant

Cdv5 Foundation
Private
United States
Unspecified amount
The CDV5 Foundation Grant supports charitable organizations, churches, and government entities that meet IRS 501(c)(3) requirements. This grant aims to nurture successful children, foster stronger families, and cultivate healthier communities. Through partnerships, the foundation provides resources to help individuals reach their full potential. Applicants may submit one request annually for operating, capital, or program support, while event sponsorships are also considered. The foundation encourages applicants to consider their budget and history with the foundation when requesting funding.
Early Childhood Development Youth Development & Leadership Education - Preschool / Early Learning +6 more

Large Grants for Nonprofit Organizations in Tennessee Highlights

Looking for large grants for nonprofit organizations in Tennessee?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Tennessee recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Tennessee

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Tennessee grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

36 Large Grants for Nonprofit Organizations in Tennessee over $25K in average grant size

24 Large Grants for Nonprofit Organizations in Tennessee over $50K in average grant size

22 Large Grants for Nonprofit Organizations in Tennessee supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Tennessee supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Tennessee?

Most grants are due in the first quarter.

Q1
32.2%
Q2
21.7%
Q3
26.3%
Q4
19.7%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Tennessee?

Grants are most commonly $12,250.

$500 $500 Min.
$12,250 $12.3 K Median
$72,415 $72.4 K Average
$2,300,000 $2.3 M Max.

Average Grant Size

What's the typical amount funded for Tennessee?

Grants are most commonly $122,522.

$122,522

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Tennessee year over year?

In 2024, funders in Tennessee awarded a total of 44,541 grants.

2022 39,759

2023 39,873

2024 44,541

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Tennessee given out in Tennessee, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Tennessee changing over time?

Funding has increased by 25.17%.

2022 $3,809,568,961

2023 $4,350,973,827
14.21%

2024 $5,446,107,598
25.17%

Tennessee Counties That Receive the Most Funding

How does grant funding vary by county?

Shelby County, Davidson County, and Knox County receive the most funding.

County Total Grant Funding in 2024
Shelby County $2,664,074,547
Davidson County $1,298,691,246
Knox County $294,292,803
Hamilton County $283,062,013
Henderson County $215,691,648