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Best Large Grants for Nonprofit Organizations in Tennessee

Find the perfect Large Grants for Nonprofit Organizations in Tennessee on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Tennessee in the United States.

9,000+

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$2.55B

Total funding

$5K

Median grant

9,000+ grants
$2.55B total
$5K median

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Never Let Go Fund

Emporia Community Foundation
Private
United States
Up to US $2,000

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Never Let Go Fund

The purpose of the Never Let Go Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood cancer. Grant requests will be considered for children under the age of 18.

Health Care Access & Delivery Cancer / Oncology Children’s Health & Pediatrics +1 more

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

Survivorship and Supportive Care Research Grant

St Baldricks Foundation Inc
Private
United States
Up to US $50,000

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

Cancer / Oncology Pediatric Cancers Patient Care & Services

HEAL Initiative: Integrative Management of Chronic Pain and Opioid Use Disorder (OUD) for Whole Recovery: Health Systems

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.
Epidemiology & Public Health Addiction & Substance Use Disorders Health Care Access & Delivery +3 more

CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) (356935)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.
Neuroscience Environmental Chemistry & Toxicology Neurological Diseases & Disorders

1890 Institution Teaching, Research, and Extension Capacity Building Grants Program (363796)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
United States
US $50,000 - US $750,000
The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.
Education - Higher Education Agriculture Workforce Preparation & Job Readiness +1 more

United States Adult Cystic Fibrosis Association (USACFA): Higher Education Scholarship

United States Adult Cystic Fibrosis Association (USACFA)
Association/Society
United States
Up to US $2,500
The United States Adult Cystic Fibrosis Association (USACFA) offers a Higher Education Scholarship, honoring Lauren Melissa Kelly. This scholarship awards up to $2500 to two adults with cystic fibrosis pursuing various educational paths. Applicants must show proof of enrollment for the relevant academic year and can cover education-related costs, including tuition and materials. This initiative not only supports education but also commemorates Lauren's legacy, inspiring others to pursue their dreams despite challenges.
Cystic Fibrosis Academic Scholarship Programs Education - Higher Education +1 more

Siemens: Charitable or Product Donations

Siemens Medical Solutions USA, Inc.
Corporate
United States
Unspecified amount
Siemens Healthineers supports charitable donations that align with its focus areas, including diagnostic imaging and oncology. They prioritize well-rated organizations that allocate a significant portion of donations to clinical efforts rather than administrative costs. Events must ensure at least 65% of funds go to the intended cause. Local chapters of national nonprofits should coordinate with their national teams for requests, as Siemens typically does not entertain separate local requests.
Biomedical Imaging Patient Care & Services Cardiovascular Diseases & Systems +1 more

RRCU Gives Foundation Grant

RRCU Gives Foundation
Association/Society
United States
Unspecified amount

RRCU Gives Foundation Grant

Mission Statement:

RRCU Gives strengthens our region by providing meaningful financial support to nonprofits addressing hunger, housing, and financial education. Through our annual grant awards and major funding initiatives, we help local organizations grow, thrive, and create lasting change.

 We award grants annually, with applications in June and awards in August.

Focus Areas

  • Hunger
  • Housing
  • Financial Education
Food Access & Hunger Financial Literacy Equitable & Affordable Housing

Siemens: Sponsorships

Siemens Medical Solutions USA, Inc.
Corporate
United States
Unspecified amount
Siemens Healthineers USA offers sponsorships to support healthcare initiatives across the U.S. They emphasize funding for healthcare organizations and related events, ensuring that requests comply with eligibility criteria. The company prioritizes diagnostic imaging, laboratory diagnostics, cardiology, and oncology. Applications must be submitted at least 45 days prior to the event, and funding is not available for sole sponsorships or certain excluded initiatives. For more information, visit Siemens Healthineers' official site.
Biomedical Imaging Patient Care & Services Cardiovascular Diseases & Systems +1 more

Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations (363814)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.
Cancer / Oncology Epidemiology & Public Health Health Care Access & Delivery +2 more

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.
Neuroscience Neurological Diseases & Disorders Stroke

Basic Needs and Income Creation

Bank Of America Charitable Foundation Inc
Private
Abbeville County, South Carolina, Ada County, Idaho +198 more
Unspecified amount
The Bank of America Charitable Foundation focuses on improving economic mobility and social progress through partnerships with nonprofits. It prioritizes basic needs, income creation, stable housing, and community empowerment. By supporting vulnerable populations, the foundation aims to enable individuals to achieve their goals and contribute positively to their communities. The foundation emphasizes sustainable progress, ensuring that all community members have access to essential resources and opportunities for growth.
Basic Human Needs Economic Services & Development Employment Services +2 more

Mishler Brown Fund Grant

Community Foundation of Elkhart County
Private
United States
Unspecified amount
The Mishler Brown Fund Grant, managed by the Community Foundation of Elkhart County, supports nonprofits dedicated to agriculture and historic preservation. Applications are accepted annually from October 1 to December 31, with funds awarded in January. Organizations must have a 501(c)(3) status but do not need to be located in Elkhart County. The fund honors Helen Mishler's legacy by preserving farming heritage, including her family's historic homestead.
Agriculture Historic Preservation Farms & Farming +1 more

ASTRO-LUNGevity Residents / Fellows in Radiation Oncology Seed Grant

LUNGevity Foundation Inc
Private
United States
Up to US $50,000
The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to enhance the research careers of residents and fellows focused on radiation oncology, specifically benefiting lung cancer patients. This initiative supports basic, translational, and clinical research endeavors. With a maximum award amount of $50,000 for one year, it provides essential funding to foster innovative projects that can lead to significant advancements in lung cancer treatment.
Cancer / Oncology Lung Cancer Biomedical Imaging

The Alice M. Ditson Fund: Organizational Support - Fall Deadline

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund offers organizational support for summer festivals and conferences focused on contemporary American classical music. This funding opportunity encourages the appreciation of works by younger, relatively unknown American composers. Eligible applicants include performing organizations and institutions that promote artistic excellence. The Fund emphasizes supporting living composers at various career stages, ensuring a broader recognition of their contributions to classical concert music. It is crucial for applicants to align their projects with the Fund's mission of enhancing public knowledge and appreciation.
Music Festivals Classical Music

Holloway Family Foundation Grant

Graham and Carolyn Holloway Family Foundation
Private
United States
Unspecified amount
The Holloway Family Foundation, established in North Central Texas, aims to enhance community quality of life regardless of race, gender, or religion. Their mission focuses on financial security, creative expression for under-resourced youth, and mentorship for personal development. The foundation supports organizations that provide workforce training, artistic opportunities for children, and guidance for youth in need. By fostering individual growth and economic stability, they empower families and strengthen communities, staying true to the founders' core values and personal experiences.
Tutoring & Mentoring Workforce Preparation & Job Readiness Youth Involvement in the Arts

AISES Indigenous Peoples Education Fund (IPEF) Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Canada +5 more
US $5,000
The AISES Indigenous Peoples Education Fund (IPEF) Scholarship offers $5,000 to support Indigenous students pursuing degrees in STEM fields. This scholarship is available to current AISES members who are full-time students and enrolled citizens or descendants of recognized Native American tribes. AISES aims to empower these students, fostering diversity in STEM while recognizing the importance of education as a tool for personal growth and community development.
STEM / STEAM Education Diversity, Equity & Inclusion Academic Scholarship Programs +3 more

Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant

National Scleroderma Foundation
Private
United States
US $200,000
The Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant, provided by the National Scleroderma Foundation, aims to support research in scleroderma-related lung disease. With a funding amount of $200,000, the grant encourages established investigators to explore innovative solutions and enhance understanding of this condition, ultimately working towards improving the quality of life for affected individuals and advancing medical knowledge in the field.
Rare Diseases Immune System Diseases Interstitial Lung Disease

AHCJ Sunshine Award

Association of Health Care Journalists (AHCJ)
Association/Society
United States
Unspecified amount

About

Building a community of journalists committed to better health care reporting.

We believe accurate, contextual and balanced health care reporting is more important than ever.

People depend on health care stories to make life-altering decisions every day.

Awards, Grants, & Fellowships

Ambitious freelancers who want to tackle an in-depth reporting project often find that the fee from a potential publisher doesn’t come close to covering their costs and time. Grants and fellowships can fill that gap, but freelancers have to know about them in order to apply. In this section, the Freelance Center is compiling a list of non-AHCJ grants, fellowships and awards (for when the hard work is done).

Sunshine Award

Presented by AHCJ’s Right-to-Know Committee

AHCJ’s Right-to-Know Committee established the Sunshine Award at Health Journalism 2026 as a way to elevate the work of journalists like STAT’s Bob Herman who fight for government transparency. We plan to continue this tradition annually from now on. Award winners receive free registration and a one-night hotel stay for our annual conference, a free year of AHCJ membership, a trophy and a certificate.

Journalism Epidemiology & Public Health Health Policy & Advocacy +2 more

Jill Botkin Hearing Health - Care Accessibility Scholarship

American Academy of Audiology
Private
United States
US $5,000
The Jill Botkin Hearing Health - Care Accessibility Scholarship, funded by the American Academy of Audiology, offers a $5,000 award to a full-time graduate student in audiology dedicated to improving access to hearing care. With nearly 50% of U.S. counties lacking nearby services, this scholarship aims to support students who demonstrate commitment through their academic achievements and personal statements. It emphasizes the importance of equitable healthcare access in underserved communities and encourages future audiologists to bridge this critical gap.
Hearing Disorders & Audiology Hearing Impairment Care & Services Health Disparities & Social Determinants of Health

AHCJ U.S. Health System Reporting Fellowship

Association of Health Care Journalists (AHCJ)
Association/Society
United States
Up to US $7,500

About

Building a community of journalists committed to better health care reporting.

We believe accurate, contextual and balanced health care reporting is more important than ever.

People depend on health care stories to make life-altering decisions every day.

AHCJ U.S. Health System Reporting Fellowship

This opportunity is for U.S.-based journalists.

Issues with the U.S. health care system are often obvious — from large swaths of uninsured residents and junk insurance plans, to high maternal mortality rates and preventable medical errors. But what is at the root of issues like these? What could an equitable health care system look like? 

Through the U.S. Health System Reporting Fellowship, supported by The Commonwealth Fund, you can pursue a significant reporting project related to the U.S. health care system at the local, regional and/or national level.

This fellowship allows mid-career journalists to maintain their regular employment while working on a major project over a 12-month calendar year. You’ll pursue the projects with the support of your newsrooms or arranged outlets, which commit to publish or air the work.

We believe that issues of health equity impact every facet of the health care system, which is why we’re specifically interested in projects focused on health equity. This might include racial disparities within a community, gaps in public health inclusion, unstable housing, insurance access, food insecurity, violence as a health issue, how health care institutions or systems are applying a racial equity lens to their policies and practices or otherwise addressing inequities or disparities, or other examinations of systemic problems that have become so apparent over the last few years.

Guidance is provided by AHCJ mentors through customized seminars on health care systems, conference calls and email consultations. The fellowship covers the cost of attending the seminars and the annual AHCJ conference, as well as a $2,500 project allowance to defray the cost of field reporting, health data analysis and other project-related research. In addition, you will receive a $5,000 fellowship award upon the successful completion of the project.

Journalism Health Disparities & Social Determinants of Health Health Care Access & Delivery +2 more

HHF: Emerging Research Grant (ERG)

Hearing Health Foundation
Private
United States
Up to US $100,000
The Hearing Health Foundation's Emerging Research Grants (ERG) program supports innovative research in hearing and balance, providing up to $50,000 per year for promising projects. Since 1958, it has fostered early-career researchers and led to significant advancements in the field. Eligible applicants must be affiliated with U.S. institutions and hold relevant advanced degrees. The program emphasizes underfunded areas and encourages applications that expand knowledge and research capabilities in hearing health.
Hearing Disorders & Audiology Meniere’s Disease Otorhinolaryngology

New Mexico Veterans Memorial Scholarship

Albuquerque Community Foundation
Private
United States
Unspecified amount
The New Mexico Veterans Memorial Scholarship, established in 2024, supports graduating high school seniors in New Mexico who embody the Medal of Honor Core Values: Courage, Sacrifice, Integrity, Commitment, Patriotism, and Citizenship. This scholarship encourages students to explore and reflect on these values through a personal essay and community service. Preference is given to students from Albuquerque High Schools, fostering a commitment to excellence and civic duty among the youth.
Education - Higher Education Vocational & Trade Education Career / College Preparation +3 more

Ronald Barnes Memorial Grant

Guild of Carillonneurs in North America
Private
North America
Up to US $14,254
The Ronald Barnes Memorial Grant, offered by The Guild of Carillonneurs in North America, supports North Americans pursuing studies in carillon performance, composition, music history, or instrument design. Established in 1998 to honor Ronald Barnes, a significant figure in carillon music, the grant has awarded over US$140,000 since 2007. For the 2025 cycle, grants of up to US$14,138 are available, depending on the number of successful applicants, promoting education in this unique art form.
Music Classical Music Music Education

Solid Waste Management Grant Program (364018)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.
Freshwater Conservation Environmental Contamination & Pollution Environmental Health +1 more

Kiwanis Club of Albuquerque Scholarship Fund

Albuquerque Community Foundation
Private
United States
Up to US $1,000
The Kiwanis Club of Albuquerque Scholarship Fund, established in 1948, supports graduating seniors from Albuquerque metro area high schools who demonstrate strong academic performance and community service. Annually, one to four scholarships of up to $1,000 are awarded to students pursuing careers in child development and teaching. The fund emphasizes the importance of community involvement and academic excellence, encouraging students to share their career goals and financial needs through an essay as part of their application.
Education - Higher Education Vocational & Trade Education Career / College Preparation +3 more

Large Grants for Nonprofit Organizations in Tennessee Highlights

Looking for large grants for nonprofit organizations in Tennessee?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Tennessee recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Tennessee

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Tennessee grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

36 Large Grants for Nonprofit Organizations in Tennessee over $25K in average grant size

24 Large Grants for Nonprofit Organizations in Tennessee over $50K in average grant size

22 Large Grants for Nonprofit Organizations in Tennessee supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Tennessee supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Tennessee?

Most grants are due in the first quarter.

Q1
32.2%
Q2
21.7%
Q3
26.3%
Q4
19.7%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Tennessee?

Grants are most commonly $12,250.

$500 $500 Min.
$12,250 $12.3 K Median
$72,415 $72.4 K Average
$2,300,000 $2.3 M Max.

Average Grant Size

What's the typical amount funded for Tennessee?

Grants are most commonly $122,522.

$122,522

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Tennessee year over year?

In 2024, funders in Tennessee awarded a total of 44,541 grants.

2022 39,759

2023 39,873

2024 44,541

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Tennessee given out in Tennessee, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Tennessee changing over time?

Funding has increased by 25.17%.

2022 $3,809,568,961

2023 $4,350,973,827
14.21%

2024 $5,446,107,598
25.17%

Tennessee Counties That Receive the Most Funding

How does grant funding vary by county?

Shelby County, Davidson County, and Knox County receive the most funding.

County Total Grant Funding in 2024
Shelby County $2,664,074,547
Davidson County $1,298,691,246
Knox County $294,292,803
Hamilton County $283,062,013
Henderson County $215,691,648