Best Large Grants for Nonprofit Organizations in Wyoming

The ORACLE 3C initiative focuses on advancing research into chronic conditions, coinfections, and comorbidities related to HIV. It aims to support early-career investigators through innovative approaches that diverge from existing methodologies. Emphasizing pediatric and maternal health, this funding opportunity encourages interdisciplinary research to better understand HIV-specific pathways and develop effective preventive and therapeutic strategies, addressing a significant public health concern.

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) invites proposals for Specialized Alcohol Research Centers (P50) to enhance interdisciplinary research on alcohol misuse and Alcohol Use Disorder (AUD). These centers aim to foster collaboration among researchers, focusing on innovative topics related to alcohol's effects on health across the lifespan. The program supports the development of research methodologies and mentorship for young investigators, addressing the complex challenges posed by alcohol misuse in society.

The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.

The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.

The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.

Gilead Sciences

At Gilead, we are relentlessly committed to advancing transformative therapies for the most serious diseases, delivering an exponentially positive impact on health.

For more than three decades, we have combined scientific rigor with a deep sense of purpose to improve health outcomes and reimagine care. Our work spans more than 35 countries with a focus on three therapeutic areas: virology, oncology, and inflammation, where unmet medical needs remain greatest.

From individual patients to whole populations, we’re committed to delivering healthier futures for people and communities worldwide.

Our Mission: To discover, develop and deliver innovative therapeutics for people with life-threatening diseases.

HIV Prevention NOVA 2026

Program Description

Gilead Sciences invites research proposals that advance the evidence base for innovative and scalable models of delivery for long-acting (LA) HIV pre-exposure prophylaxis (PrEP) in the United States.

This Topic of Interest (TOI) is focused on care delivery models implemented in non-traditional settings, defined as clinical and non-clinical environments where PrEP services are not routinely provided. Emphasis is placed on approaches that reflect real-life practice and address gaps in current PrEP delivery infrastructure.

Persistent inequities in PrEP uptake in the U.S. suggest that expanding availability within traditional clinical settings alone is unlikely to reach all populations with unmet PrEP need.1,2 Rigorous implementation studies in non-traditional settings where PrEP services are not routinely provided are needed to evaluate whether these models can reduce access barriers and improve equitable reach among individuals who may benefit from PrEP.2,3,4

The goal of this TOI is to generate practical, decision-relevant evidence that informs how LA PrEP can be implemented, scaled, and sustained in real-life U.S. settings.

The Life Comes From It Grant, funded by the Tides Foundation, supports grassroots initiatives focused on restorative, transformative, and indigenous justice. It prioritizes projects led by communities of color, emphasizing alternatives to incarceration and community-led solutions. Applicants must be 501c3 organizations based in the United States. This grant fosters a collaborative approach to healing and justice, aiming to shift power dynamics and promote inclusive practices across generations.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

About

A History Of Making Waves

Carnival Foundation oversees the many philanthropic endeavors of Carnival Corporation as well as its employee-driven service group, the “Friends Uniting Neighbors” (F.U.N.) Team.

Carnival Foundation’s contributions are widespread, touching the communities where the brands visit and operate. From the cities where our brands are headquartered to ports we visit around the world, we endeavor to make a difference to the lives of many.

Through monetary and in-kind donations, innovative philanthropic programs, employee fundraisers and hands-on volunteer initiatives, Carnival Foundation and the brands of Carnival Corporation support a variety of organizations. Whether it’s providing meals to the homeless and abuse prevention or working toward medical advancement and educating youth, Carnival Foundation’s reach is communitywide.

In-Kind Donations

To apply for an in-kind donation from Carnival Foundation, submit an online application complete with the following information:

• A letter of request with a brief description of the organization including its legal name, history, activities, purpose and governing board
• Contact name and information, including phone number and address for the individual who is organizing the event
• Name and date of the event
• Average amount of funds raised from the auction in previous years and estimated number and demographics of the event audience
• Description of how funds raised from the donation will be used within the organization
• List of other cruise suppliers, if any, participating in the event
• An outline with details of Carnival’s publicity/promotional opportunities associated with the event
• Copy of Internal Revenue Service determination letter indicating 501© (3) tax-exempt status as an organization that is not a private foundation.
• Copy of organization’s most recent 990 filed with the Internal Revenue Service
• Geographical area(s) served

What We Do

Since our creation by Congress in 1984, NFWF has grown to become the nation’s largest private conservation foundation. We work with both the public and private sectors to protect and restore our nation’s fish, wildlife, plants and habitats for current and future generations.

NFWF supports conservation efforts across all 50 states and U.S. territories. Since our founding, we've funded over 23,300 rigorously evaluated projects, awarded to both large environmental organizations and small local initiatives. We do not fund advocacy or litigation, and do not conduct membership campaigns. Instead, we focus on achieving results and building a better future for our world.

Northern Great Plains Program

The National Fish and Wildlife Foundation (NFWF) is soliciting proposals to voluntarily conserve and restore grasslands and wildlife species in the Northern Great Plains. The goal of the Northern Great Plains program is to maintain and/or improve interconnected grasslands in focal areas to sustain healthy populations of grassland-obligate species while fostering sustainable livelihoods and preserving cultural identities including tribal cultures and food sovereignty. Major funding partners include the U.S. Fish and Wildlife Service, U.S. Forest Service, Natural Resources Conservation Service (NRCS), Bureau of Land Management, Bezos Earth Fund, Marathon Oil, Altria Group, Occidental Petroleum Corporation, and Margret A. Cargill Philanthropies.

About

A History Of Making Waves

Carnival Foundation oversees the many philanthropic endeavors of Carnival Corporation as well as its employee-driven service group, the “Friends Uniting Neighbors” (F.U.N.) Team.

Carnival Foundation’s contributions are widespread, touching the communities where the brands visit and operate. From the cities where our brands are headquartered to ports we visit around the world, we endeavor to make a difference to the lives of many.

Through monetary and in-kind donations, innovative philanthropic programs, employee fundraisers and hands-on volunteer initiatives, Carnival Foundation and the brands of Carnival Corporation support a variety of organizations. Whether it’s providing meals to the homeless and abuse prevention or working toward medical advancement and educating youth, Carnival Foundation’s reach is communitywide.

Grants Or Sponsorships

To apply for a grant or sponsorship from Carnival Foundation, prospective applicants must complete an online application and include the following information and documents:

• A letter of request with a brief description of the organization, including its legal name, history, activities, purpose and governing board
• Purpose for which the grant is requested
• Grant amount requested
• Listing of other sources of financial support
• Operating budget of the project for which the funds are requested
• Organization’s annual budget
• Copy of the organization’s most recent audited financial statement
• Copy of organization’s most recent 990 filed with the Internal Revenue Service
• Copy of Internal Revenue Service determination letter indicating 501© (3) tax-exempt status as an organization that is not a private foundation
• Organization’s completed W-9 form
• Geographical area(s) served
• Organizations applying for a grant renewal must submit a final report detailing use of the prior grant award. Interim and final reports will be submitted through our online portal.

The Holloway Family Foundation, established in North Central Texas, aims to enhance community quality of life regardless of race, gender, or religion. Their mission focuses on financial security, creative expression for under-resourced youth, and mentorship for personal development. The foundation supports organizations that provide workforce training, artistic opportunities for children, and guidance for youth in need. By fostering individual growth and economic stability, they empower families and strengthen communities, staying true to the founders' core values and personal experiences.

The Thoroughbred Education and Research Foundation (TERF) offers grants to support thoroughbred health, welfare, and education. Focused on enhancing equine research and safety in racing, TERF prioritizes funding for scholarships, educational programs, and veterinary medicine. Eligible applicants must be recognized 501(c)(3) organizations, with a commitment to transparency in reporting. This initiative aims to significantly impact the thoroughbred industry by fostering improved care and understanding of these horses, contributing to their overall welfare.

The Thoroughbred Education and Research Foundation (TERF) offers grants to support education and research related to Thoroughbred horses. The foundation prioritizes funding for scholarships, educational programs, and equine research aimed at promoting thoroughbred health and welfare. Eligible applicants include qualified 501(c)(3) organizations, while those previously funded must submit reports before applying again. Notably, TERF does not provide funds for facilities caring for unwanted horses or cover overhead costs for grants.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Land Conservation and Indigenous Languages Scholarship

The purpose of the Land Conservation and Indigenous Languages Scholarship is to provide financial assistance to eligible American Indian and Alaska Native undergraduate and graduate students enrolled full-time at an accredited institution and pursuing degrees with a focus in Indigenous languages, natural resources, land management, and conservation or cultural preservation. 

This opportunity is a need-based award.

Raptor Research Foundation

RRF Mission Statement: The Raptor Research Foundation advances the science, conservation, and understanding of birds of prey.

The Raptor Research Foundation (RRF) is the world’s largest professional society for raptor researchers and conservationists. Founded in 1966 as a non-profit organization, our primary goal is the accumulation and dissemination of scientific information about raptors. The Foundation organizes annual scientific conferences and provides competitive grants and awards for researchers and conservationists. The Foundation also provides support and networking opportunities for students and early career raptor researchers.

William Andersen Student Presentation Awards

The Awards: The William C. Andersen Memorial Awards are given to both the best student oral and poster presentation at the annual RRF meeting. This award can only be given to a student once per degree (bachelor, master, or doctorate). To be eligible, a student must be senior author and presenter of the paper or poster.

Students wishing to apply for this award should indicate their interest by checking the box on the abstract submission form. 

Amount

The poster award recipient receives $325, 1-year free membership to RRF, and waived page charges to publish their research in the Journal of Raptor Research. The recipient must be the primary author and the paper must reflect what the award was for.

The paper award recipient receives $525, 1-year free membership to RRF, and waived page charges to publish their research in the Journal of Raptor Research. The recipient must be the primary author and the paper must reflect what the award was for.

About William Andersen

The William C. Andersen Award was established in 1982 in memory of Bill Andersen, who drowned in 1980 while canoeing the Churchill River in Manitoba during a Peregrine Falcon survey. Dr. Andersen was a chemistry professor, but his first love was raptors. He established the Ornithology Research Center at Otero Jr. College in La Junta Colorado, as a medium for raising funds for the field research he conducted with his students. His interest in raptors of southeastern Colorado grasslands naturally evolved into developing a solution to the universal problem of raptor persecution. He established a rehabilitation facility and tirelessly lectured to service clubs and school groups about the benefits of raptors. He was a strong supporter of the RRF and a number of students accompanied him to each of the annual meetings. His enthusiasm, sincerity, and humor sparked an interest in raptors among many of his students and associates. While participating in the 1980 North American Peregrine Falcon Survey, Bill and a partner were canoeing on the Churchill River in northern Manitoba. They unexpectedly encountered extremely turbulent water and capsized. Bill disappeared and presumably drowned. In that instant, raptors and those inspired by them lost one of their strongest allies.

The upcoming National Institute of Mental Health (NIMH) funding opportunity aims to explore the effects of HIV immunotherapies on central nervous system (CNS) outcomes. It seeks to identify mechanisms, benefits, and risks associated with these therapies, focusing on overcoming CNS-specific barriers. The initiative encourages collaborations to develop strategies for achieving sustained virologic remission and improving neurological outcomes for individuals with HIV, particularly targeting neurotoxicity and neuroinflammation.

The Goodnow Fund is a family foundation that provides approximately $1.5 million in grants annually to nonprofit organizations. Focused on supporting vulnerable children, Alzheimer's research, educational opportunities for low-income students, and environmental improvement, the Fund primarily aids organizations in Fairfield County, Connecticut. It identifies potential grantees directly and does not accept unsolicited proposals. For more information, organizations can contact the Fund's Executive Director.

The Ryan White HIV/AIDS Program Part B Supplemental Grant aims to provide essential funding to support HIV care and treatment services across states and territories. This program supplements existing formula-based funding from the RWHAP Part B and ADAP, improving access to necessary resources for those affected by HIV/AIDS. By enhancing support structures, it addresses critical healthcare needs, ensuring better health outcomes for vulnerable populations.

The Reader’s Digest Partners for Sight Foundation offers Single Program Grants to support impactful programs for individuals who are blind or visually impaired. These grants, ranging from $25,000 to $50,000, prioritize initiatives that enhance independence and service delivery. Eligible organizations must be US 501(c)(3) non-profits, and unsolicited proposals are not accepted. The foundation emphasizes community-based solutions and invites qualified applicants to submit a Letter of Inquiry followed by a full proposal.

The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.

The NIDCD Mentored Research Education Pathway (R25) aims to enhance research education for otolaryngology residents and medical students. This program provides essential career development activities and mentored research experiences, fostering a new generation of researchers in biomedical and clinical sciences. By focusing on specialized training, it supports the recruitment of individuals from diverse backgrounds into impactful research careers, ultimately benefiting the field of otolaryngology and related health sciences.

About

With deep roots in California’s Central Valley, The Save Mart Companies and its family of stores prides itself in being a part of neighborhoods and putting people first. Our dedication to customers is reflected in the connections we’ve made in the communities we’ve served for more than 70 years.

The Save Mart Companies CARES Foundation

In 2000, we established The Save Mart Companies CARES Foundation, our philanthropic, non-profit organization, supporting programs and organizations that provide vital resources for children and families in the communities we serve. The CARES Foundation focuses on building stronger communities through fresh foods, accessibility, and programs that support youth and helping them to thrive. Annually, The CARES Foundation contributes approximately $500,000 in small grants to support community-based, non-profit organizations.

The Save Mart Companies CARES Foundation Grant

The CARES Foundation’s focus is building stronger communities through fresh foods, access to food, and programs that support youth and helping them thrive.

The CARES Foundation will review, on a quarterly basis, among other things, the breadth of the audience served; the likely impact in the community; the importance of the need to be addressed in the community; and the community reputation, service history, and financial stability of the group or program seeking funds. No one of these or other factors will necessarily be weighted more heavily than another. Instead, each group or program will be measured against all groups and 2 programs seeking funding at the time. For example, a program serving a small segment of the community but that addresses an especially important community need, and thus has the potential for a strong and meaningful impact, would be favored over a group serving a wider clientele but that fills a less important community need. Requests for Grants should be a minimum of $500.00 up to $10,000.00. Programs and organizations requesting smaller grants should contact the Store Manager of the nearest Save Mart Companies’ store location for request consideration.

Recipients that receive grants for more than one year must demonstrate meaningful outcomes for the previous investment made by The CARES Foundation.

Emma E. Hill Memorial Scholarship Fund

Mission Statement

The Emma E. Hill Memorial Scholarship Fund was established to memorialize Emma by helping female swimmers pursue their dreams of a college education. The scholarship awards will be granted on an annual basis to female graduating high school senior athletes in Southern Chester County.

About Emma

Emma was an excellent student as a sophomore at Unionville High School (UHS). She loved to swim and was a dedicated member of both the Kennett YMCA Sea Dragons and UHS swim teams. In her spare time, Emma was a lifeguard and also taught young children how to swim at the Y. As a younger child and teenager, Emma excelled on the ballfield in URA softball.

At the young age of 16, Emma passed away following complications caused by a rare type of gastric cancer, a form of the disease that was unheard of in a child and unfortunately found too late. Throughout Emma’s brief illness, she was strong and determined to get better, and did not let her health issues define her in any way.

Emma was beautiful in every sense of the word, and was loved throughout her community and beyond. She worked hard at whatever she was trying to accomplish, but always with a cheery, exuberant attitude and lovely smile. More than anything, her absolute kindness and warm heart are what made Emma our sweet girl.

The Little Giraffe Foundation, a national non-profit based in Chicago, provides NICU Support Grants ranging from $100 to $1,000. Since 2011, they have positively impacted countless families by delivering over 32,000 gift bags and funding essential research. These grants aim to enhance the experience for parents and patients in neonatal intensive care units, supporting initiatives like holiday gift bags and resources for bonding with babies. Applications are welcomed from eligible U.S.-based institutions.