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Best Buffalo County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Buffalo County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

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$3.82B

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$5K

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$3.82B total
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Dr. Martin Luther King, Jr. Regional Scholarship

Bay Area Community Foundation
Private
United States
Approximately US $1,000

About Us

Bay Area Community Foundation is a nonprofit organization created by and for the people of the Bay Area. We offer a range of flexible giving tools to help our donors make a positive impact on the community and causes that align with their interests and passions. In addition to first-rate donor service, we manage our community’s permanent endowment and award grants to address the community’s most pressing needs and promising opportunities.

Since 1982, our community has used our resources to make charitable gifts more effective. We provide maximum flexibility in establishing, managing, and distributing your gifts. Through our donors’ generosity, we can help support arts and culture, community initiatives, education and youth, environment, health and wellness, human services, and recreation in our area.

Dr. Martin Luther King, Jr. Regional Scholarship

Inspired by the belief that love and peaceful protest can eliminate social, political, and economic injustice, Dr. Martin Luther King, Jr., became this nation’s most heralded civil right leader. He aroused blacks and whites alike to protest racial discrimination, war, and poverty. A champion of nonviolent resistance to oppression, he was awarded the Nobel Peace Prize in 1964. Dr. King’s life ended at the age of 39 on April 4, 1968, when he was assassinated in Memphis, Tennessee. However short his life was, he greatly advanced the cause of civil rights in this nation. His life serves as an encouragement to each of us to do all that we can to end injustice.

The Dr. Martin Luther King, Jr. Regional Scholarships are awarded each year to Bay County high school seniors (regardless of ethnicity) who actively embrace Dr. King’s dream of improving racial harmony and social justice. The scholarship award(s) will be at least $1,000 and are non-renewable. The scholarship award(s) will be presented at the annual Great Lakes Bay Regional Martin Luther King, Jr. Celebration program held each January.

This scholarship is also available to Midland and Saginaw County students through their respective community foundations.

Education - High School Academic Scholarship Programs Education - Higher Education +1 more

Multiple Sclerosis Foundation: Transportation Assistance Grant

Multiple Sclerosis Foundation Inc
Private
United States
Unspecified amount

Transportation Assistance Grant

The Transportation Assistance Grant program was established to help members of the MS community remain as independent as possible, and ensure all people with MS have the transportation necessary to get the best medical care.

The program provides funding for reasonable paratransit fees. In partnership with Lyft and Uber, the program can also provide funding for transportation to and from appointments for MS care, limited to neurologist visits and infusion centers, at no cost to the person with MS.

Multiple Sclerosis

Cardiovascular Disease Prevention and Treatment Funding: Priority 1

South Dakota Department of Health
State/Local Government
South Dakota
Up to US $7,500

South Dakota Department of Health

The South Dakota Department of Health (SD DOH) strives to promote, protect, and improve the health of all South Dakotans with information, licensing, and more.

Cardiovascular Disease Prevention and Treatment Funding

The South Dakota Department of Health is pleased to announce a funding opportunity, the Cardiovascular Disease Prevention and Treatment funding. This funding opportunity is intended to support strategies that have a focus on prevention, treatment and/or management of cardiovascular disease. The facilities awarded funding through this opportunity will receive funds and technical assistance to create and expand sustainable programs to help link resources that support self-management and lifestyle changes to address those at increased risk for CVD with a focus on hypertension management.

The South Dakota Department of Health (SD DOH) Heart Disease and Stroke Prevention Program (HDSPP) is offering funding to meet one or both of the following priorities: Priority 1: Self-Measured Blood Pressure (SMBP) Program; and Priority 2: Care Coordination Program.

Priority 1: Self-Measured Blood pressure (SMBP) Program

Self-Measured Blood Pressure (SMBP) Program supports the implementation and expansion of Self-Measured Blood Pressure Monitoring programs through partnerships with local healthcare facilities and clinics. These programs are designed to help individuals with hypertension manage their condition effectively by monitoring their blood pressure at home in conjunction with clinical support.

Cardiovascular Diseases & Systems Home Health Care

Cardiovascular Disease Prevention and Treatment Funding: Priority 2

South Dakota Department of Health
State/Local Government
South Dakota
Up to US $30,000

South Dakota Department of Health

The South Dakota Department of Health (SD DOH) strives to promote, protect, and improve the health of all South Dakotans with information, licensing, and more.

Cardiovascular Disease Prevention and Treatment Funding

The South Dakota Department of Health is pleased to announce a funding opportunity, the Cardiovascular Disease Prevention and Treatment funding. This funding opportunity is intended to support strategies that have a focus on prevention, treatment and/or management of cardiovascular disease. The facilities awarded funding through this opportunity will receive funds and technical assistance to create and expand sustainable programs to help link resources that support self-management and lifestyle changes to address those at increased risk for CVD with a focus on hypertension management.

The South Dakota Department of Health (SD DOH) Heart Disease and Stroke Prevention Program (HDSPP) is offering funding to meet one or both of the following priorities: Priority 1: Self-Measured Blood Pressure (SMBP) Program; and Priority 2: Care Coordination Program.

Priority 2: Care Coordination Program

Care Coordination program supports a patient-centered healthcare delivery model that provides comprehensive, proactive, and coordinated management for individuals with multiple chronic conditions, while explicitly identifying and addressing the non-medical social and environmental factors that impact their well-being.

Chronic Illnesses Health Disparities & Social Determinants of Health Cardiovascular Diseases & Systems

South Dakota Walkable Communities’ Active Transportation Assessment Collaboration Grant

South Dakota Department of Health
State/Local Government
South Dakota
Unspecified amount

South Dakota Department of Health

The South Dakota Department of Health (SD DOH) strives to promote, protect, and improve the health of all South Dakotans with information, licensing, and more.

‘South Dakota Walkable Communities’ Active Transportation Assessment Collaboration

The South Dakota Department of Health will provide one South Dakota community (or two communities as an inter-community project) with technical assistance (provided by South Dakota State University Landscape Architect Students) in conducting active transportation assessments and providing recommendations for improving the built environment to increase walkability and bike-ability within that community or joint communities.

Applicants are highly encouraged to consider the specific walkability needs and challenges of priority populations when completing the applications.

Pedestrian & Bike-Friendly Infrastructure Public Transportation & Mass Transit Systems

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $10,000 - US $40,000

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

  • Training programs
  • Programs that engage new adopters and grow the market share for adoption
  • Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
  • Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

  • Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
  • Decrease length of stay
  • Decrease cost of care
  • Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

Animal Welfare - General Animal Welfare - Domestic Animals & Pets

ASPCA Right Horse Grants to Amplify Adoptions and Support Community Equines

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $5,000 - US $50,000
The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.
Animal Welfare - General Animal Welfare - Domestic Animals & Pets

Driving University Impact: Expanding the Public Exchange Network Grant

Social Science Research Council
Private
United States
US $300,000

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

  • The tools, templates and training they need to start right away;
  • A shared brand they can plug into on day one;
  • A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

Humanities & Social Science Homelessness Services Disaster Relief / Humanitarian Aid +1 more

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.
Epidemiology & Public Health Patient Care & Services Biomedical Imaging +1 more

Powered & Prepared Initiative Grant

Hillman Family Foundations
Private
U.S. Territories, United States
US $300,000

About Henry L. Hillman Foundation

Henry L. Hillman Foundation inspires, invests in, and leverages great ideas to improve the quality of life in Pittsburgh and southwestern Pennsylvania.

Backup Power When Your Community Needs It

The Powered & Prepared Initiative seeks proposals from nonprofit and municipal organizations in southwestern Pennsylvania for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Southwestern Pennsylvania is increasingly impacted by severe weather events that cause widespread power outages and disruptions. The Powered & Prepared Initiative, supported by Henry L. Hillman Foundation, seeks proposals from nonprofit and municipal organizations for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Basic Human Needs Emergency Medical Care & Services Disaster Relief / Humanitarian Aid +2 more

Building the Future Workforce Challenge Grant

Caterpillar
Corporate
Brazil, India +2 more
US $1,000,000

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

Workforce Preparation & Job Readiness Vocational & Trade Education Manufacturing Engineering +2 more

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders (2026-06-26)

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

Hematological Systems

Pediatric Hidradenitis Suppurativa Challenge Grant

Pediatric Dermatology Research Alliance Inc
Private
United States
Up to US $50,000

Pediatric Hidradenitis Suppurativa Challenge Grant

Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.

To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.

Focus

Proposals should address one or more of the following high-priority research topics:

  • Predicting treatment effectiveness and risk utilizing real world evidence and/or experience
  • Early disease and factors involved in severe disease development
  • Optimizing surgical and procedural approaches to minimize pain, shorten healing time, and reduce recurrence
  • Improving recruitment of diverse and representative populations for clinical studies, trials and advanced therapeutics

Funding:

  • Up to $50,000 to support one year of research
  • One award anticipated for this funding cycle
Children’s Health & Pediatrics

The Alpha Omega Alpha/Pharos Poetry Award

Alpha Omega Alpha Honor Medical Society
Private
United States
US $1,500

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.

Poetry Education - Higher Education

Summer Medical Internship Program (SMIP)

The Society of Interventional Radiology Foundation
Association/Society
United States
Up to US $6,000

Summer Medical Internship Program (SMIP)

Fosters an interest in research by funding a summer research project conducted by a medical student.

The SIR Foundation Summer Medical Internship Program introduces medical students to interventional radiology research and medical device development. The goal of this program is to foster an interest in research by funding a summer research project conducted by a medical student.

Students applying for the program must show strong potential for a career in IR with proven academic success. Selected students will have an opportunity to intern with an interventional radiologist research mentor or corporate research and development mentor for 8 weeks during the summer.

SIR Foundation will provide a $6,000 stipend to help ease the financial burdens throughout their internship experience.

  • Budget: Up to $6,000
  • Grant Length: Eight weeks
Apprenticeship & Internship Programs Medical Education & Professional Training

Hilcorp Future Leaders of America Scholarship

Greater Houston Community Foundation
Private
United States
Up to US $10,000

Hilcorp Future Leaders of America Scholarship

Benefiting select communities across the United States where Hilcorp operates.

The Hilcorp Future Leaders of America Scholarship Program was developed to give back to the communities in which Hilcorp Energy Company operates to develop future leadership talent as the next innovators, educators, and business leaders.

Award Amount

Multiple scholarships awarded annually. The scholarship is comprised of up to four (4) annual awards of $2,500, for a total award of up to $10,000.

The four annual (4) awards may be received over a period of up to 6 years, allowing for deferment if needed.

Education - Higher Education Career / College Preparation

GBA1 Parkinson's Disease Research Catalyst Program

Michael J Fox Foundation For Parkinsons Research
Private
Canada, United Kingdom +1 more
Up to US $300,000

GBA1 Parkinson's Disease Research Catalyst Program

The GBA1-PD Research Catalyst Program seeks to build a deeper, globally integrated understanding of GBA1-associated Parkinson’s disease by aligning efforts across geographies and maximizing the value of shared datasets and research assets. Funding will support hypothesis- driven projects with an emphasis on integrative, cross-cohort analyses and the systematic characterization and standardization of models to enable broad use by the research community.

Funding

Duration: 12 to 24 months

Award Amount: Up to $300,000. Requested support should be commensurate with work proposed.

These budgets include direct and indirect costs. For academic and for-profit institutions, no more than 15% or 10%, respectively, may go to indirect costs. 

Parkinson’s Disease

Patrick J. Kiley/Houston AGC Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

Patrick J. Kiley / Houston AGC Scholarship

Benefiting employees, dependents of employees, and/or interns of AGC Houston member firms OR students involved in AGC Student Chapters.

Award Amounts

Multiple awards are given each year. Scholarship award amounts will vary for each selected scholarship recipient.

Vocational & Trade Education

Investigating the Benefit of Early Treatment with Ritlecitinib in Alopecia Areata: A Real-World Evidence Approach

Pfizer, Inc.
Corporate
United States
Up to US $100,000

Investigating the Benefit of Early Treatment with Ritlecitinib in Alopecia Areata: A Real-World Evidence Approach

Alopecia Areata (AA) is a chronic, immune-mediated condition causing nonscarring hair loss that affects about 2% of the global population and can lead to substantial psychosocial burden if disease is severe and untreated. The treatment landscape has recently evolved with the approval of ritlecitinib, a systemic therapy for severe AA in adults and adolescents aged 12 years and older, based on efficacy demonstrated in the ALLEGRO phase 2b/3 program.

Despite this advance, important questions remain regarding the optimal timing of therapy initiation. Emerging post-hoc analyses from the ALLEGRO program indicate that patients with shorter disease duration and lower baseline severity achieve higher response rates, suggesting that earlier intervention with ritlecitinib may lead to improved outcomes.

Geographic Scope

United States 

Funding Range and Project Length

Individual projects requesting up to $100,000 USD will be considered.

Maximum project length is 24 months.

Skin Diseases & Dermatology

Hemophilia Fellowship

Pfizer, Inc.
Corporate
United States
Up to US $100,000

Hemophilia Fellowship

This competitive grant program seeks to support an institution-based fellowship that emphasizes shared decision making (SDM), patient education, and multidisciplinary team-based care. The intent is to strengthen the hemophilia care through equitable education, and patient-centered shared decision making in a rapidly evolving treatment landscape.

Geographic Scope

  • United States 

Funding Range and Project Length

  • Grant funding is available to support a one year fellowship up to $100.000 USD. 
Hematological Systems

Jon Christopher Gauss, Jr. Wrestling Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Jon Christopher Gauss, Jr. Wrestling Scholarship Fund, established by his parents, supports high school wrestlers pursuing post-secondary education at accredited institutions. This initiative, part of the Community Foundation of Washington County MD, aims to honor Jon's legacy while empowering students to achieve their educational goals. The scholarship enhances community engagement and provides vital financial assistance to promising athletes, ensuring that their dedication to wrestling translates into academic success.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

SDAC Interim Grant: Organizations

South Dakota Arts Council
State/Local Government
South Dakota
Up to US $1,000

South Dakota Arts Council 

Established in 1966 and funded by the State Legislature and the National Endowment for the Arts, the South Dakota Arts Council (SDAC) is a state agency serving South Dakotans and their communities through the arts. Recognizing the importance of creativity in the lives of all South Dakotans, the Council makes quality arts accessible throughout the state by providing grants, services and information to artists, arts organizations, schools and the public. The Council is the advisory board to the SDAC staff within the Department of Tourism. Council members are appointed by the Governor.

Interim Grants

Funding for special arts projects or unexpected opportunities. Activities must take place before June 30, 2027. Regular season programming is not funded.

The Interim Grants fund 1) Organizations and 2) Educators.

Organizations 

Funding

  • Up to 50% of project costs (max $1,000)
  • Dollar-for-dollar match required

Examples of Use

  • Special arts activities
  • Transportation for K–12 students or individuals with disabilities
  • Expert help with programs, administration, or technology
  • Professional development for staff or board members
  • Other special opportunities may also be considered
Art & Culture

SDAC Interim Grant: Educators

South Dakota Arts Council
State/Local Government
South Dakota
Up to US $1,000

South Dakota Arts Council 

Established in 1966 and funded by the State Legislature and the National Endowment for the Arts, the South Dakota Arts Council (SDAC) is a state agency serving South Dakotans and their communities through the arts. Recognizing the importance of creativity in the lives of all South Dakotans, the Council makes quality arts accessible throughout the state by providing grants, services and information to artists, arts organizations, schools and the public. The Council is the advisory board to the SDAC staff within the Department of Tourism. Council members are appointed by the Governor.

Interim Grants

Funding for special arts projects or unexpected opportunities. Activities must take place before June 30, 2027. Regular season programming is not funded.

The Interim Grants fund 1) Organizations and 2) Educators.

Educators 

Funding

  • Up to $1,000 for project costs
  • No match required
  • The teacher is the applicant, not the school. Funds are paid directly to the teacher.

Examples of Use

  • Classroom supplies
  • Teacher workshops or conferences
  • Creating arts curriculum
  • Guest artists in the classroom
  • Student field trips to unique arts events
  • Technology for arts learning
  • Other special opportunities may also be considered
Art Education Education - K through 12 Curriculum Development +1 more

Citi Foundation Blueprint for Housing Grant

Citi Foundation
Corporate
Alameda County, California, Alexandria City, Virginia +51 more
US $1,000,000

Our Work:

The Citi Foundation commits $20 million to help nonprofit housing developers overcome financial and operational barriers to building and preserving affordable housing in the U.S.

Apply for Funding

Citi Foundation primarily provides funding through open Requests for Proposals (RFP). This model enables us to engage and support a broad range of organizations across the globe to tackle some of the most pressing social issues of our time. Each RFP launched is accompanied by detailed information on goals, selection criteria and relevant application deadlines.

Housing Affordability

Citi's Blueprint for Housing Opportunity

Recognized as the number one affordable housing lender in the U.S. by Affordable Housing Finance magazine, Citi knows increasing supply is essential to addressing housing affordability — one of the defining economic challenges of our time. That’s why we are putting our capital, community impact and expertise toward helping more Americans access housing they can truly afford.

Equitable & Affordable Housing Nonprofit Growth & Development

Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Paul Calabresi Career Development Award for Clinical Oncology aims to enhance the training of clinician-scientists in clinical and translational cancer research. This funding opportunity encourages the career growth of researchers but does not permit Scholars to lead independent clinical trials. Instead, it allows participation in clinical trials under the mentorship of an experienced researcher, fostering a collaborative approach to cancer research.
Cancer / Oncology Biotechnology Health Policy & Advocacy +1 more

Partnership Agreement Grants, FY 2027

National Endowment for the Arts (NEA)
Federal Government
American Samoa, Guam +4 more
US $400,000 - US $1,500,000
The National Endowment for the Arts (NEA) offers Partnership Agreement Grants for FY 2027 to support state and regional arts agencies. These grants enhance community access to the arts and leverage federal funding to attract additional state resources. By enabling agencies to create state arts plans, the NEA fosters a collaborative approach that strengthens the arts landscape across the nation, ensuring that local needs and priorities are addressed effectively.
Art & Culture Arts / Culture Access & Participation Art Education +2 more

HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000 - US $750,000
The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.
Epidemiology & Public Health Addiction & Substance Use Disorders Drug Use Disorder +2 more

Buffalo County Grants for Nonprofits Highlights

Looking for Buffalo County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Buffalo County grants recommended for your specific programs in South Dakota.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Buffalo County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Buffalo County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Buffalo County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538