Upcoming Webinar
Instrumentl Fall Launch: Your Grant Operating System Has Leveled Up.
Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Buffalo County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Buffalo County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.82B

Total funding

$5K

Median grant

9,000+ grants
$3.82B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

8,990 Results based on applied filters

The Woman’s National Farm and Garden Association (WNF&GA) Scholarship for the Study of Conservation and Natural Resources Management

Woman's National Farm and Garden Association, Inc.
Association/Society
United States
US $4,000
The Woman's National Farm and Garden Association (WNF&GA) Scholarship supports graduate students pursuing careers in conservation and natural resource management. This annual scholarship aims to continue the legacy of conservationists dedicated to protecting our planet's resources. Eligible candidates must demonstrate a strong commitment to environmental stewardship through their academic and community involvement. However, WNF&GA members and their immediate families are excluded from eligibility. The scholarship is a vital resource for future leaders in conservation.
Environmental Conservation Natural Resources

ASM Minority Travel Award

American Society for Microbiology
Association/Society
United States
Unspecified amount
The ASM Minority Travel Award aims to enhance diversity in microbial sciences by supporting faculty from underrepresented institutions, including community colleges and historically black colleges. This initiative ensures that diverse perspectives are included in the field, fostering a richer academic environment. Awardees receive complimentary registration and housing for ASM Microbe 2026, promoting professional development and networking opportunities in microbiology.
Microbiology

Science: Experimental Physics Investigators Initiative

Gordon E And Betty I Moore Foundation
Private
United States
Up to US $1,300,000
The Experimental Physics Investigators Initiative, launched by the Gordon E. and Betty I. Moore Foundation, aims to support mid-career scientists in experimental physics. With a funding of $1,250,000 over five years, this program encourages innovative research and collaboration among scientists. Applicants from U.S. institutions are invited to submit pre-proposals, with about 50% advancing to full proposals. The initiative fosters inclusivity and equity while aiming to make significant impacts in the field of experimental physics.
Physics

NCP Open Road Fund

Nexus Community Partners
Private
Minnesota, North Dakota +1 more
Approximately US $50,000
The NCP Open Road Fund is a transformative initiative aimed at empowering Black individuals in Minnesota, North Dakota, and South Dakota by providing $50 million in grants. This fund focuses on fostering financial well-being, economic power, education, housing, and health. By supporting projects that enhance wealth creation and community healing, the fund aims to create sustainable pathways for Black families and individuals to thrive and build intergenerational wealth.
Black American Services

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This funding opportunity aims to foster innovative mechanistic research on precision probiotic therapies, utilizing a phased R61/R33 award mechanism. The goal is to identify and understand individual variations influencing probiotic responses, thereby enhancing clinical outcomes. The R61 phase focuses on uncovering unique biological patterns over two years, while the R33 phase applies findings to improve probiotic responsiveness through rigorous studies. Ultimately, this initiative seeks to overcome barriers in personalized probiotic interventions.
Microbiomes

Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,400,000
This funding opportunity aims to advance innovative mechanistic research to enhance precision probiotic therapies. It invites R33 applications that explore individual differences affecting probiotic responses, identifying subgroups of effective responders. The goal is to develop strategies addressing variability in human probiotic responses, influenced by factors like microbiome, genetics, and lifestyle. Applicants should conduct rigorous studies using appropriate models to deepen understanding of these relationships and improve clinical outcomes in probiotic interventions.
Microbiology Microbiomes

RMS-SEPM Scholarships: Edwin D. McKee Grant

Society for Sedimentary Geology (SEPM)
Association/Society
Arizona, Colorado +7 more
US $2,000
The RMS-SEPM Scholarships, specifically the Edwin D. McKee Grant, provides $2,000 for undergraduate and graduate students conducting sedimentological research in the Rocky Mountain region. Sponsored by the Society for Sedimentary Geology, this scholarship aims to support students at universities within the U.S. Preference is given to those studying in states like Montana, Colorado, and New Mexico, promoting a deeper understanding of sedimentology and its applications.
Geology

RMS-SEPM Scholarships: Fluvial Sedimentology Research Grant

Society for Sedimentary Geology (SEPM)
Association/Society
Arizona, Colorado +7 more
US $2,000
The RMS-SEPM Scholarships for Fluvial Sedimentology Research Grant supports Ph.D. or Master’s degree candidates conducting research in fluvial sedimentology. This $2,000 grant is exclusively available to students at U.S. universities, specifically those engaged in studies or research in states like Montana, North Dakota, and Colorado. The Society for Sedimentary Geology (SEPM) offers this opportunity to foster academic growth in sedimentology and related fields.
Geology

Animal and Veterinary Innovation Centers (U18)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $7,500,000
The Animal and Veterinary Innovation Centers (U18) funding opportunity, led by the FDA, aims to foster collaborations with academic institutions to tackle critical veterinary health challenges. This includes addressing Highly Pathogenic Avian Influenza, promoting genomic advancements in agriculture, and developing veterinary solutions for minor species. Applications are invited to enhance animal health and public safety, with Letters of Intent due prior to the July 2024 deadline.
Genetics & Genomics Epidemiology & Public Health Veterinary Science & Services +2 more

Asian Cultural Council: New York Fellowship

Asian Cultural Council Inc
Private
Afghanistan, Bangladesh +18 more
Unspecified amount
The Asian Cultural Council's New York Fellowship offers a transformative six-month program for artists, scholars, and arts professionals from Asia. Participants engage deeply with New York City's vibrant cultural landscape, attending performances, exhibitions, and workshops while building networks with local communities. This unique opportunity fosters peer-learning and individual artistic development, encouraging fellows to incorporate their experiences into their practices and contribute to their home cultures. The fellowship emphasizes exploration, exchange, and support, culminating in a rich cultural immersion.
Art Conservation Architecture Archaeology +10 more

Asian Cultural Council: Individual Fellowship

Asian Cultural Council Inc
Private
Afghanistan, Bangladesh +18 more
Unspecified amount
The Asian Cultural Council's Individual Fellowship provides artists, scholars, and arts professionals from Asia and the United States with opportunities for self-directed cultural exchange and research in unfamiliar regions. This program supports activities such as interviews, workshops, and archival research, fostering cultural immersion and collaboration. With a funding limit of $35,000, the fellowship encourages innovative proposals that enhance creative perspectives and relationships among peers, while also ensuring strong eligibility criteria for applicants.
Archaeology Architecture Museums & Cultural Institutions +10 more

Asian Cultural Council: Graduate Fellowship

Asian Cultural Council Inc
Private
United States
US $15,000
The Asian Cultural Council's Graduate Fellowship provides financial support for travel and living expenses to graduate students from Asia studying in the U.S. It offers $15,000 for one academic year, potentially renewable for another year, covering essential costs while pursuing full-time coursework. This initiative fosters international cultural exchange and enhances academic training in the arts. Eligible applicants must be enrolled full-time in accredited graduate programs and commit to at least two consecutive semesters of study.
Art Conservation Archaeology Museums & Cultural Institutions +9 more

Asian Cultural Council: Organization Grant

Asian Cultural Council Inc
Private
Afghanistan, Bangladesh +18 more
Up to US $50,000
The Asian Cultural Council (ACC) offers Organization Grants to arts and culture organizations in Asia and the U.S., promoting cultural exchange through travel and collaborative activities. These grants support immersive experiences, research, and access to artistic communities, fostering international dialogue and relationship-building. Organizations must be nonprofit or educational institutions, legally registered in eligible regions, and demonstrate a minimum of five years of relevant programming. ACC provides additional support to enhance project feasibility.
Art & Culture Cross-Cultural Understanding & Exchanges Artist Training & Development

PFF Research Fund to Cure Pulmonary Fibrosis - PFF Scholars

Pulmonary Fibrosis Foundation
Private
United States
US $100,000
The PFF Research Fund to Cure Pulmonary Fibrosis aims to support innovative research that enhances understanding and treatment of pulmonary fibrosis. The PFF Scholars Program provides $100,000 over two years to early-stage researchers, encouraging them to pursue independent funding opportunities. Eligible applicants include post-doctoral trainees and early Assistant Professors committed to interstitial lung disease research. This initiative fosters mentorship and collaboration, ultimately advancing the field and improving patient care.
Respiratory Diseases & Systems

Kalamazoo Valley Chapter - Stanley Weber Projects Fund

Trout Unlimited, Inc.
Private
United States
Up to US $5,000
The Kalamazoo Valley Chapter's Stanley Weber Projects Fund honors a dedicated member by supporting projects that enhance coldwater fisheries and their habitats. Offering grants up to $5,000 annually, the fund prioritizes non-profit initiatives that foster conservation, restoration, and public education while promoting volunteer engagement. Recognition through plaques or media announcements is requested for grant recipients, ensuring the legacy of Stanley Weber continues to impact the community positively.
Habitat & Ecosystem Restoration Fisheries Freshwater Conservation +1 more

Advanced Technological Education (355100)

National Science Foundation (NSF)
Federal Government
United States
US $475,000 - US $7,500,000
The Advanced Technological Education (ATE) program, supported by the National Science Foundation (NSF), focuses on enhancing the education of technicians in high-technology fields through partnerships between two-year institutions, industry, and economic development agencies. This program emphasizes faculty-led projects and credit-bearing courses, aiming to improve science and engineering technician education while also supporting professional development and career pathways for students and incumbent workers.
Vocational & Trade Education Education - Higher Education Emerging Technology Development +2 more

Strategic Planning Grant Program

Attainable Edge LLC
Corporate
United States
US $10,000 in in-kind support
The Strategic Planning Grant Program by Attainable Edge LLC aims to provide accessible and affordable strategic planning resources to 501(c)3 non-profit organizations. Awardees will receive a one-year subscription to innovative software and consulting services, enabling them to align their teams and enhance their strategic goals. This initiative focuses on empowering organizations to effectively engage with their communities and achieve significant positive change through structured planning and collaboration.
All fields of work

Sammy Cahn Award

Ascap Foundation
Private
District of Columbia, Puerto Rico +1 more
US $5,000
The Sammy Cahn Award, presented by The ASCAP Foundation, honors exceptional lyric-writing talent among songwriters of original songs. Established in 1995 to commemorate Sammy Cahn's legacy, the award offers a $5,000 prize to recipients. Eligible entrants include ASCAP writer members in good standing or independent songwriters. Submissions are judged anonymously based on lyric quality and overall craft, ensuring the recognition of artistic excellence within the songwriting community.
Music

Catalyst Award for Innovative Research Approaches for AMD

Research To Prevent Blindness Inc
Private
United States
Up to US $300,000
The Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration (AMD) provides $300,000 in funding to U.S. researchers exploring novel treatments and understanding of AMD. This initiative, co-funded by partners such as the American Macular Degeneration Foundation, encourages high-risk, high-gain research that could lead to significant advancements in AMD therapies. Each award is designed to support innovative projects that are not yet in clinical trials, fostering groundbreaking work in vision science.
Eye Diseases & Disorders

Disney Award for Amblyopia Research

Research To Prevent Blindness Inc
Private
United States
Up to US $150,000
The Disney Award for Amblyopia Research, funded by Research To Prevent Blindness Inc, aims to advance research in amblyopia diagnosis and treatment. Grants of up to $150,000 will support exceptional ophthalmic scientists conducting significant research. Eligible nominees include U.S. researchers from various academic ranks, with a focus on independent research. Proposals should highlight relevance to amblyopia's pathophysiology, diagnosis, or treatment, with awards available until Spring 2025.
Eye Diseases & Disorders

Medical Student Eye Research Fellowship

Research To Prevent Blindness Inc
Private
United States
Approximately US $30,000
The Medical Student Eye Research Fellowship offers a unique opportunity for medical students to dedicate a year to research in ophthalmology, focusing on any vision-related topic. Supported by Research to Prevent Blindness and other partners, the fellowship includes a $30,000 grant and potential additional funding for relocation. Eligible candidates must be U.S. citizens or permanent residents and be nominated by RPB-supported Chairs. The program aims to promote diversity and innovation in vision research.
Eye Diseases & Disorders

Stein Innovation Award

Research To Prevent Blindness Inc
Private
United States
Up to US $300,000
The Stein Innovation Award supports innovative vision research by providing funding to Department of Ophthalmology faculty and other researchers. With deadlines in January and July, the award encourages projects that advance the understanding of the visual system and related diseases. Eligible candidates must be affiliated with U.S. institutions of higher education, and prior nomination forms are required for application acceptance. This initiative aims to foster groundbreaking research in the field of ophthalmology.
Eye Diseases & Disorders

Exemplary Pathways to STEM Graduate Education: Planning

Alfred P Sloan Foundation
Private
United States
Up to US $75,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs. By addressing barriers in graduate education, the initiative seeks to promote equitable learning environments. Planning grants will support collaborations that assess needs and develop systemic changes to enhance pathways for students in STEM fields, ensuring that all students can thrive in their academic pursuits.
Astronomy & Astrophysics Biology Chemistry +10 more

Exemplary Pathways to STEM Graduate Education: Seed

Alfred P Sloan Foundation
Private
United States
Up to US $250,000
The Alfred P. Sloan Foundation's initiative, "Creating Equitable Pathways to STEM Graduate Education: Seed," aims to enhance graduate education access for students from Minority Serving Institutions (MSIs). The program provides grants of up to $500,000 to foster partnerships between MSIs and various higher education institutions. Projects should focus on overcoming barriers to success in graduate studies, including recruitment and admission processes, thereby promoting equitable learning environments in STEM fields.
Astronomy & Astrophysics Biology Chemistry +10 more

Exemplary Pathways to STEM Graduate Education: Implementation

Alfred P Sloan Foundation
Private
United States
Up to US $500,000
The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs to enhance equitable learning environments. Grants of up to $500,000 will support projects addressing systemic barriers, promoting effective practices, and ensuring seamless transitions from MSIs to advanced degrees in various STEM fields. The initiative seeks to create lasting impacts on student access and success in graduate education.
Astronomy & Astrophysics Biology Chemistry +10 more

Medical Student Mentored Summer Research Program

North American Society For Pediatric Gastroenterology, Hepatology & Nutrition
Association/Society
Canada, United States
Up to US $4,000
The Medical Student Mentored Summer Research Program offers medical students in the U.S. and Canada a unique opportunity to engage in a 10-week research experience under expert mentorship in pediatric gastroenterology, hepatology, or nutrition. With a stipend of $4000 paid in installments, this program is designed for students who have completed at least their first year of medical training. Preference is given to those seeking research experience between their first and second years.
Digestive System Health & Diseases Nutrition & Healthy Eating

NASPGHAN Foundation/NASPGHAN George Ferry Young Investigator Development Award

North American Society For Pediatric Gastroenterology, Hepatology & Nutrition
Association/Society
Canada, Mexico +1 more
US $150,000
The NASPGHAN Foundation/NASPGHAN George Ferry Young Investigator Development Award supports promising clinical, quality improvement, translational, or basic science research focused on gastrointestinal tract diseases, liver, pancreas, and nutritional disorders in children. Eligibility includes being a NASPGHAN member for at least two years, having a recent fellowship, and holding a junior faculty position. This award fosters innovative research to enhance pediatric gastroenterology and improve child health outcomes.
Digestive System Health & Diseases

Buffalo County Grants for Nonprofits Highlights

Looking for Buffalo County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Buffalo County grants recommended for your specific programs in South Dakota.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Buffalo County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Buffalo County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Buffalo County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538