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Best Clay County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Clay County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

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9,150 Results based on applied filters

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed) (357655)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.
Chronic / Acute Pain Anesthesia and Pain Medicine Drug Use Disorder +1 more

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) (357658)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Limited Competition Small Grant Program under the NCATS CTSA aims to enhance the research capabilities of scholars transitioning to independent academic translational scientists. This program supports diverse clinical and translational science projects, including pilot studies and methodology development. The R03 grants are designed for short-term projects with limited resources that generate preliminary data for future R01 applications, thereby fostering innovation and advancing health research.
Science Biology Health & Medicine +2 more

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) (357667)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,250,000
The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.
Health & Medicine Pharmacology Biomedical informatics +4 more

Outdoor Recreation Legacy Partnership Program (ORLP) Recurring Notice 5 Year

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $15,000,000
The Outdoor Recreation Legacy Partnership Program (ORLP) is a competitive grant initiative by the National Park Service, aimed at enhancing parks and recreational opportunities in urban, underserved communities. This program supports the acquisition, development, and renovation of outdoor recreation areas through federal funding, addressing the needs of community organizations, local governments, and recognized tribes. Applications are accepted twice a year, before June 1 and November 1.
Parks & Public Spaces Outdoor Recreation Outdoor Equity

U.S. Hillman Prize for Opinion and Analysis Journalism

The Sidney Hillman Foundation Inc
Private
United States
US $5,000
The U.S. Hillman Prize for Opinion and Analysis Journalism, awarded by the Sidney Hillman Foundation, recognizes outstanding journalism that serves the common good. Open to journalists globally, the prize honors works published or broadcast in English within the last year. Winners receive a $5,000 honorarium and a certificate at a ceremony in New York City. This prestigious award promotes impactful storytelling that resonates with a U.S. audience and champions social justice.
Journalism News Media & Communications

U.S. Hillman Prize for Broadcast Journalism

The Sidney Hillman Foundation Inc
Private
United States
US $5,000
The U.S. Hillman Prize for Broadcast Journalism, awarded by the Sidney Hillman Foundation, recognizes outstanding journalism that serves the common good. Open to global journalists, the contest honors work accessible to U.S. audiences, with no entry limits per outlet. Winners receive a $5,000 honorarium and a certificate at a ceremony in New York City. This prestigious award highlights impactful stories across various media platforms, emphasizing the importance of journalism in addressing social issues.
Journalism News Media & Communications Television +1 more

NCAA Postgraduate Scholarship - Winter Sports

National Collegiate Athletic Association
Private
Canada, Puerto Rico +2 more
US $10,000
The NCAA Postgraduate Scholarship for Winter Sports awards up to 126 scholarships of $10,000 annually to outstanding student-athletes who excel both academically and athletically. Eligible candidates are in their final year of NCAA competition and must have a minimum GPA of 3.2. The scholarships are available for men and women in various winter sports and are intended for use in accredited graduate programs, emphasizing the importance of academic achievement and community involvement.
Sports & Athletics Hockey Swimming +2 more

NCAA Postgraduate Scholarship - Spring Sports

National Collegiate Athletic Association
Private
Canada, Puerto Rico +2 more
US $10,000
The NCAA Postgraduate Scholarship for Spring Sports is awarded to exceptional student-athletes who are in their final year of competition and have maintained a minimum GPA of 3.2. Each year, 126 scholarships of $10,000 are provided, split equally between male and female athletes across various sports. This initiative, established in 1964, aims to promote graduate education and recognizes not just athletic excellence, but also academic achievements and community involvement.
Sports & Athletics Baseball & Softball Tennis +1 more

NCAA Division II Degree Completion Award

National Collegiate Athletic Association
Private
Alabama, Alaska +45 more
Up to US $15,000
The NCAA Division II Degree Completion Award provides financial assistance to student-athletes who have exhausted their athletics eligibility, enabling them to complete their first undergraduate degree. Since its inception in 2001, nearly $9 million has supported approximately 1,875 athletes, with a remarkable 90 percent graduation rate among recipients. The award covers tuition costs up to $15,000 for remaining credits and may be used in the summer term or short terms surrounding the final undergraduate year.
Sports & Athletics

NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed) (357511)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.
Science Biology Medical Education & Professional Training +3 more

PFund Foundation: Sponsorship Fund

Philanthrofund Foundation Inc
Private
Iowa, Minnesota +3 more
US $250 - US $1,000
The PFund Foundation offers a Sponsorship Fund for events primarily serving LGBTQ+ communities in the upper Midwest. With sponsorship amounts ranging from $500 to $1,000, organizations can apply once per calendar year. Applications must be submitted at least 60 days prior to the event and include information on the event's impact and how funds will be used. PFund aims to foster equity and strengthen networks within its focus areas.
LGBTQIA+ Services

Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to address the urgent mental health crisis in the U.S. by promoting research that enhances access to evidence-based practices for youth. It encourages applications focusing on interventions for underserved populations, including those facing housing and food insecurities. Researchers are invited to explore strategies for improving service delivery, overcoming workforce challenges, and integrating care into accessible settings, ultimately striving for equitable mental health services for all youth.
Mental Health & Psychiatric Diseases Children’s Mental Health

NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08) aims to enhance the careers of clinical scientists committed to cancer research. This NIH-supported program provides protected time for research and encourages underrepresented individuals in health-related sciences. With deadlines spanning from 2025 to 2027, the program focuses on training and developing the skills necessary to compete for significant research funding and address health disparities in cancer research.
Cancer / Oncology Medical Education & Professional Training

Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional) (357550)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.
Cancer / Oncology Liver Disease Health Disparities & Social Determinants of Health

NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.
Biology Health & Medicine Medical Education & Professional Training +1 more

Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional) (357572)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Interventions to Reduce Sleep Health Disparities (R01) grant aims to fund non-pharmacological strategies that enhance sleep health and address disparities in sleep among affected populations. The program emphasizes innovative approaches to examine sleep as a crucial element in mitigating health disparities across various health outcomes. Deadlines for applications range from February 2025 to June 2027, supporting both standard and renewal submissions under the National Institutes of Health.
Health Disparities & Social Determinants of Health Sleep

Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) (357568)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The Research Enhancement Award Program (REAP) aims to boost basic and clinical research at health professional and graduate schools that have historically received limited NIH funding. By supporting small-scale research projects led by faculty, REAP fosters student engagement in significant research endeavors, enhancing their educational experience. Eligible institutions must grant advanced degrees in health professions and have received under $6 million in NIH support in four of the last seven years, promoting broader participation in the nation's biomedical research efforts.
Medical Education & Professional Training Biology Health & Medicine

Tribal Agriculture Fellowship: Career and Technical Education Students

Native American Agriculture Fund
Private
United States
Unspecified amount
The Tribal Agriculture Fellowship supports career and technical education students in agriculture, focusing on Native American, Alaska Native, and Native Hawaiian individuals. This last-dollar fellowship aims to fill financial gaps, allowing students to prioritize their education while participating in developmental activities. Eligible students must maintain academic progress and engage in community support initiatives. The fellowship provides resources for tuition, housing, and professional development over up to four years, promoting agricultural knowledge in tribal communities.
Education - Higher Education Agriculture Vocational & Trade Education

Klingenstein-Simons Fellowship Awards in Neuroscience

The Esther A And Joseph Klingenstein Fund Inc
Private
United States
Up to US $450,000
The Klingenstein-Simons Fellowship Awards in Neuroscience support early-career investigators conducting basic or clinical research focused on neurological and psychiatric disorders. Awardees receive $150,000 annually for three years, aimed at fostering innovative research that contributes to understanding and treating these disorders. The fellowship encourages applications from underrepresented groups and prioritizes candidates with promising scientific careers who may not have received substantial prior funding, promoting collaboration and mentorship in the neuroscience community.
Neuroscience

CLRA Research Grant Program

Childrens Leukemia Research Assn Inc
Private
United States
Up to US $30,000
The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.
Leukemia

NLSOT Graduate Student Travel Award

Society of Toxicology
Association/Society
Minnesota, Montana +2 more
Unspecified amount
The NLSOT Graduate Student Travel Award aims to assist graduate students from the Northland SOT region with travel costs to the national SOT Annual Meeting. This award encourages student involvement in local chapter activities and can be used for various travel-related expenses, including registration, airfare, lodging, and meals. By supporting student participation, the award fosters academic growth and networking opportunities within the toxicology community.
Environmental Chemistry & Toxicology

NLSOT Postdoctoral Travel Award

Society of Toxicology
Association/Society
Minnesota, Montana +2 more
Unspecified amount
The NLSOT Postdoctoral Travel Award aims to support postdoctoral researchers from the Northland SOT region by covering travel costs to the national SOT Annual Meeting. This initiative encourages their participation in chapter activities, fostering professional development and collaboration. Eligible expenses include meeting registration, airfare, hotel accommodations, and meals, making it a valuable opportunity for emerging scientists to engage with the broader toxicology community.
Environmental Chemistry & Toxicology

Vilcek Foundation Grants

The Vilcek Foundation Inc
Private
American Samoa, Guam +4 more
US $5,000 - US $20,000
The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.
Immigrant Services Art & Culture Education - Higher Education +1 more

Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed) (357113)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Technology Development Research for Establishing Feasibility and Proof of Concept (R21) grant supports innovative projects aimed at developing new technologies with high potential impact in biomedical research. Applicants are encouraged to submit Letters of Intent 30 days before application deadlines, which are set for February, June, and October from 2025 to 2027. This funding opportunity is administered by the NIH, focusing on high-risk, high-reward exploratory research.
Biotechnology Emerging Technology Development Medical Technology, Devices, and Equipment +1 more

Focused Technology Research and Development (R01 Clinical Trial Not Allowed) (357112)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Focused Technology Research and Development (R01) grant supports innovative projects aimed at developing technologies to enhance biomedical research. This funding opportunity emphasizes the creation of laboratory instruments, algorithms, and biological systems that can significantly improve research capabilities. Key deadlines for applications are set for February, June, and October of 2025 through 2027, ensuring ample time for proposal submissions. The initiative is funded by the National Institutes of Health (NIH), part of the US Department of Health and Human Services.
Biotechnology Biomedical Imaging Medical Technology, Devices, and Equipment +1 more

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,000,000
The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.
Environmental Health

Impact100 Global Veterans Awards

Impact100 Global Veterans
Private
American Samoa, Guam +4 more
Up to US $100,000
The Impact100 Global Veterans Awards empower women to make a significant difference by awarding grants up to $100,000 to nonprofits that serve veterans. Focus areas include art and culture, education, health and wellness, environment, and family initiatives, promoting the well-being and support of veterans across the United States. Eligible organizations must meet specific criteria, including tax-exempt status, and are encouraged to submit proposals that utilize funds effectively within two years.
Art & Culture Military & Veterans Services Educational Access & Equity +17 more

Clay County Grants for Nonprofits Highlights

Looking for Clay County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Clay County grants recommended for your specific programs in South Dakota.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Clay County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Clay County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Clay County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538