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Best Clay County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Clay County, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

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9,150 Results based on applied filters

Core Research Grants: Future of Work

Russell Sage Foundation
Private
United States
Up to US $200,000
The Future of Work program by the Russell Sage Foundation investigates the decline in quality of low-wage jobs in the U.S. It explores factors such as outsourcing, immigration, union decline, and technological changes. Current research focuses on minimum wage impacts, offshoring effects, and job search behaviors influencing employment outcomes, particularly for women and minorities in the post-recession labor market. This grant aims to enhance understanding of these critical issues affecting low-education workers.
Employment Services Workers’ Rights

Core Research Grants: Race, Ethnicity, and Immigration

Russell Sage Foundation
Private
United States
Up to US $200,000
The Russell Sage Foundation's Core Research Grants program focuses on Race, Ethnicity, and Immigration, aiming to foster interdisciplinary research on the changing demographics of the U.S. population. This initiative encourages innovative collaboration among social scientists to enhance research quality and support the ideals of a pluralistic society. By building on insights from previous programs, it seeks to address critical questions concerning race and ethnicity within the context of immigration.
Immigration & Refugee Rights Racial / Ethnic Justice & Rights Humanities & Social Science

Core Research Grants: Social, Political, and Economic Inequality

Russell Sage Foundation
Private
United States
Up to US $200,000
The Russell Sage Foundation’s Core Research Grants program addresses social, political, and economic inequalities in the U.S. It investigates the factors contributing to these disparities and their impact on various outcomes, including education and civic participation. Launched in 2001 and renamed in 2018, the program aims to enhance understanding of how inequalities affect mobility and representation. Researchers with a doctorate or substantial experience are encouraged to apply, fostering high-level scholarly research in this critical field.
Humanities & Social Science Economics Political Science +2 more

Core Research Grants: Behavioral Science and Decision Making in Context

Russell Sage Foundation
Private
United States
Up to US $200,000
The Russell Sage Foundation's Core Research Grants support innovative research in Behavioral Science and Decision Making. This program emphasizes interdisciplinary approaches, inviting insights from economics, psychology, sociology, and law to enhance our understanding of decision-making processes across various societal contexts. Applications are open to scholars with a doctorate, focusing on critical issues such as policing, housing, and immigration, while encouraging a blend of theoretical and empirical research to inform public policy.
Economics Psychology Political Science +9 more

Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed) (357250)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.
Drug Use Disorder Addiction & Substance Use Disorders Drug Safety

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (357256)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.
Stroke

NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports talented postdoctoral researchers in transitioning to independent faculty positions. This program provides essential NCI research funding to facilitate the development of competitive, independent research careers. Applications are due by 5:00 PM local time of the applicant's organization, emphasizing the importance of timely submissions for prospective awardees.
Biology Health & Medicine Medical Education & Professional Training

Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.
Cancer / Oncology Drug Safety

Research Opportunities for New and At-Risk Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Research Opportunities for New and At-Risk Investigators (R01 Clinical Trial Optional) program invites applications that promote workforce diversity in health-related sciences. This initiative encourages researchers from underrepresented backgrounds to propose independent research projects in alignment with NIH's mission. Important deadlines for standard and renewal applications range from February 2025 to November 2027. This effort aims to enhance diversity and inclusion within the scientific community.
Science Health & Medicine Diversity, Equity & Inclusion +1 more

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) (357282)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,125,000
The Academic Research Enhancement Award (AREA) supports small-scale research at institutions that receive limited NIH funding, emphasizing biomedical research for undergraduate students. This program aims to enhance the research environment and provide valuable experiences for students. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over four of the last seven years. This funding opportunity encourages investigator-initiated minimal risk clinical trials to advance NIH missions.
Biology Health & Medicine Medical Education & Professional Training

Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) (357288)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.
Preventative Healthcare Health Disparities & Social Determinants of Health Addiction & Substance Use Disorders +3 more

NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required) (357301)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Multi-Site Feasibility Clinical Trials (R01) invites applications for clinical trials focused on mind and body interventions. This program emphasizes the need for multisite feasibility studies to gather essential data for future efficacy trials. The initiative is designed to enhance public health by addressing gaps in scientific knowledge related to the delivery, recruitment, and data collection of integrative health approaches. Deadlines for submissions range from February 2025 to October 2026.
Integrative & Alternative Health

LUNGevity VA Research Scholar Award

LUNGevity Foundation Inc
Private
United States
US $50,000 - US $100,000
The LUNGevity VA Research Scholar Award supports innovative lung cancer research within the Department of Veterans Affairs, with a focus on early detection and treatment methods relevant to veterans. The maximum award is $100,000, distributed over two years, contingent upon satisfactory progress. Applications are now open for the 2025 cycle, with funding aimed at improving outcomes and developing individualized treatment strategies, including targeted therapies and immunotherapies.
Lung Cancer Military & Veterans Services

LUNGevity Career Development Award

LUNGevity Foundation Inc
Private
United States
US $100,000 - US $300,000
The LUNGevity Career Development Award supports emerging research leaders focused on lung cancer. It funds innovative projects aimed at enhancing early detection and personalized treatments, including targeted therapies and immunotherapy. With a maximum award of $300,000 over three years, this opportunity is limited to US applicants. The funding is contingent upon annual progress reviews, with the first payment expected after November 1, 2025. This award aims to foster groundbreaking advancements in lung cancer research.
Lung Cancer

ASTRO-LUNGevity Residents / Fellows in Radiation Oncology Seed Grant

LUNGevity Foundation Inc
Private
United States
Up to US $50,000
The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to enhance the research careers of residents and fellows focused on radiation oncology, specifically benefiting lung cancer patients. This initiative supports basic, translational, and clinical research endeavors. With a maximum award amount of $50,000 for one year, it provides essential funding to foster innovative projects that can lead to significant advancements in lung cancer treatment.
Cancer / Oncology Lung Cancer Biomedical Imaging

Capacity Accelerator for Tribal Offshore Wind Engagement

United States Department of Energy (DOE)
Federal Government
United States
Up to US $565,000
The Capacity Accelerator for Tribal Offshore Wind Engagement, launched by the U.S. Department of Energy, aims to empower Tribal Nations in offshore wind energy decision-making. This initiative offers up to $7.1 million in cash prizes and technical assistance through three phases: Capacity Needs, Capacity Development, and Engagement. Each phase is designed to support Tribes in outlining their priorities, building capacity, and implementing impactful projects in offshore wind energy.
Renewable/Sustainable Energy Native American Services Wind Energy +1 more

Stanley C. Israel Regional Award for Advancing Diversity in the Chemical Sciences

American Chemical Society
Association/Society
United States
US $1,250 - US $2,750
The Stanley C. Israel Regional Award for Advancing Diversity in the Chemical Sciences recognizes individuals or institutions promoting inclusiveness in the chemical sciences. This award includes a medal, a $1,250 grant, and reimbursement for travel expenses up to $1,500 for attending the ACS regional meeting where the award is presented. Eligible nominees must foster programs that increase participation from diverse groups in the chemical enterprise.
Chemistry Diversity, Equity & Inclusion

ASHP Foundation Compounded Sterile Preparations Training Awards Program

American Society Of Health System Pharmacists Research And Education Foundation (ASHP)
Private
United States
US $1,000
The ASHP Foundation Compounded Sterile Preparations (CSP) Training Awards Program supports pharmacists engaged in CSP responsibilities by providing educational sessions and training opportunities. It aims to enhance competency through the ASHP Sterile Compounding Designated Person Training, which includes immersive experiences and practical sessions. Funded by the Lawrence A. Trissel Pharmacy Legacy Fund, the program offers full-meeting registration, training registration, and travel stipends to two deserving recipients, fostering professional growth and excellence in pharmacy practice.
Pharmacology

NIA Postdoctoral Fellowship Award to Promote Broad Participation in Translational Research for AD/ADRD (F32 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIA Postdoctoral Fellowship Award aims to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This fellowship supports promising candidates from diverse backgrounds in developing essential translational research skills. The program emphasizes interdisciplinary approaches to treatment, prevention, and early detection of AD/ADRD while providing research experience under the guidance of mentors in clinical trials, fostering a diverse and effective research community.
Dementia & Alzheimer’s Disease Medical Education & Professional Training

NIA Predoctoral Fellowship Award to Promote Broad Participation in Translational Research for AD/ADRD (F31 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIA Predoctoral Fellowship Award aims to enhance diversity in the translational research workforce focusing on Alzheimer's disease and related dementias. This funding opportunity supports promising predoctoral candidates from underrepresented backgrounds, fostering their research training and skills in various aspects of AD/ADRD. By encouraging interdisciplinary teamwork, the program seeks to develop a diverse workforce capable of contributing significantly to the prevention, treatment, and management of these conditions.
Dementia & Alzheimer’s Disease Medical Education & Professional Training

Industrial Energy Storage Systems Prize

United States Department of Energy (DOE)
Federal Government
United States
Up to US $700,000
The Industrial Energy Storage Systems Prize, sponsored by the U.S. Department of Energy, offers $4.8 million to promote innovative thermal energy storage solutions for the industrial sector. With three phases from 2025 to 2026, participants can win cash prizes by developing cost-effective concepts to enhance energy efficiency. This initiative encourages the adoption of sustainable technologies to address energy demands while reducing the strain on the electric grid, supporting the overall decarbonization goals of the industry.
Energy Renewable/Sustainable Energy Public Infrastructure +1 more

Friends of Reservoirs: Small Grant

Friends of Reservoirs
Private
United States
More than US $3,500
The Friends of Reservoirs: Small Grant program offers annual grants of $2,000 to member organizations of Friends of Reservoirs, with additional product donations bringing the total value over $3,500. This initiative, supported by generous sponsors, aims to enhance reservoir fisheries habitats. Applicants should note a $25 application fee, which contributes directly to the grant fund. This program focuses on fostering community engagement and improving aquatic ecosystems.
Fisheries

Friends of Reservoirs: Mossback Grant

Friends of Reservoirs
Private
United States
US $1,000
The Friends of Reservoirs: Mossback Grant offers three grants of $1,000 in Mossback products to eligible members of Friends of Reservoirs organizations. Sponsored by Mossback Fish Habitat, these grants aim to enhance structural habitat in public waters. The total retail value is approximately $1,500. Applicants must cover freight costs, and a $25 application fee applies to each submission. This initiative supports habitat restoration efforts across member organizations.
Habitat & Ecosystem Restoration Fisheries Freshwater Conservation

Disaster Relief and Resilience Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Disaster Relief and Resilience Scholarship supports residents of western North Carolina whose education funding has been affected by Hurricane Helene. Offered by the North Carolina Community Foundation, this scholarship is available for undergraduate and graduate students attending two- or four-year colleges. The minimum award is $1,000, aimed at helping students overcome financial hardships caused by the disaster and continue their educational pursuits.
Education - Higher Education Disaster Relief / Humanitarian Aid

Bass Pro Shops Large Grant

Friends of Reservoirs
Private
United States
Up to US $100,000
The Friends of Reservoirs: Large Grant supports fish habitat enhancement projects in manmade reservoirs, promoting conservation and partnerships. With approximately $250,000 in Federal funding and $500,000 from Bass Pro Shops, grants up to $75,000 are available. Projects must match funding and can be multi-year, with specific caps on subsequent funding. This initiative aims to address habitat impairments and enrich community quality of life through improved fishing opportunities.
Habitat & Ecosystem Restoration Fisheries Freshwater Conservation +1 more

Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (358375)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.
Indigenous Health Systems Native American Services Health Disparities & Social Determinants of Health

Intervention Research to Improve Native American Health (R34 Clinical Trial Optional) (358373)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The Intervention Research to Improve Native American Health (R34) aims to support research that enhances health interventions for Native American populations. This includes studying the efficacy of health promotion and disease prevention strategies, culturally informed treatments, and addressing existing health disparities. The initiative encourages community-based solutions that are sustainable and adaptable to various Native American tribes. Key deadlines for grant applications are set for October 2025 and 2026, with additional dates for AIDS-related proposals.
Health Disparities & Social Determinants of Health Indigenous Health Systems Native American Services

Clay County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Clay County grants recommended for your specific programs in South Dakota.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Clay County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Clay County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Clay County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538