Best Grants for New Nonprofits in Colorado

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The Sally Beck Fund, managed by the El Pomar Foundation, supports nonprofit organizations dedicated to equine rescue, care, and therapeutic riding. Grants aim to enhance equine welfare, particularly for those with 501(c)(3) status. However, funds cannot be allocated for capital improvements or staffing overhead. The application process occurs biannually, ensuring consistent support for these vital equine-related initiatives.

The CO Educational Stability Grant, administered by the Colorado Department of Education, aims to support educational stability for highly mobile students, including those in foster care, experiencing homelessness, or migrants. Established by House Bill 18-1306 in 2018, the program focuses on removing educational barriers, improving attendance, and increasing graduation rates for these vulnerable populations. By providing academic and social-emotional support, the grant seeks to enhance educational outcomes for students facing high mobility challenges.

The SWE Rocky Mountain Section College Scholarship provides financial support for women pursuing degrees in ABET accredited engineering, computing, or engineering technology programs in Colorado and Wyoming. Three scholarships, each with a minimum value of $1,000, are awarded annually. Eligible applicants must identify as women, maintain a GPA of 3.0 or higher, and be enrolled in an eligible program. This initiative honors pioneering women engineers and aims to encourage the next generation of female leaders in STEM.

The Region 4 Professional Development Awards for 2025-2026 foster the growth of health information access and data science skills among network members. This funding supports diverse projects such as workshops, conferences, and educational activities aimed at enhancing the professional capacity of individuals affiliated with NNLM Region 4. By encouraging proposals that address the needs of underrepresented communities, the awards aim to improve health information services and access across the region.

The Rupert Dunklau Foundation Grant supports organizations with 501(c)(3) status, focusing on Lutheran Higher Education, Health and Human Care, and Faith Strengthening. Since its establishment in 1968, the foundation has aimed to provide financial resources to ministries within the Lutheran tradition, particularly in Nebraska and surrounding states. Eligible projects must align with the foundation's mission to promote the welfare of mankind through educational and health initiatives.

The Sumners Foundation Grant aims to engage and educate the public about self-government through various programs, including civic education, democracy reform, and teacher training. Grants are available to qualified 501(c)(3) organizations primarily in Texas, New Mexico, and Oklahoma, supporting activities that foster civic engagement and understanding of democratic principles. The Foundation emphasizes direct involvement in the political process and does not fund political activities or provide individual grants.

CommonSpirit Health offers the Community Health Improvement Grant to enhance health equity and service systems for underserved populations. Through collaborative efforts with 501(c)(3) organizations, this initiative provides financial support for essential health projects. Grant amounts range from $19,500 for small grants to $150,000 for standard grants, varying by hospital. Participating hospitals include those under Catholic Health Initiatives and Dignity Health, aimed at addressing significant community health needs.

The Colorado Creates Grant, offered by the Colorado Office of Economic Development and International Trade, supports nonprofit arts organizations in Colorado. This competitive grant program provides general operating support based on the applicant's cash operating revenue. Eligible organizations must have been active for at least three years, hold a cash operating budget of at least $25,000, and focus on arts activities. The grant fosters collaboration and community engagement, aiming to enhance economic growth through the creative sector.

The Marvin R. and Pearl E. Patterson Family Fund Scholarship, offered by the Grand Haven Area Community Foundation, supports students aspiring to study graphic or fine arts, as well as those interested in environmental sciences. Open to high school graduates from the Tri-Cities area, this scholarship considers leadership, community involvement, and academic achievements, although financial need is not a requirement. Applicants must provide transcripts and relevant documents to qualify for this opportunity.

The Enbridge Community Grant aims to enhance the quality of life in North American communities through strategic donations and sponsorships. With funding ranging from $1,000 to $10,000, the grant supports organizations focused on safety, education, environmental stewardship, and Indigenous culture. Enbridge encourages early applications, with decisions typically made within eight weeks. The grant seeks to empower local initiatives that foster community strength, vibrancy, and sustainability.

The Strategic Alliance Matching Grant by the NCAA Division III aims to bolster ethnic minority and gender representation in senior athletics administration roles. With an annual budget of $1.6 million, it supports up to 46 schools and conferences over five years. Eligible institutions must be active NCAA Division III members and meet various requirements. This grant encourages diversity in leadership, fostering an inclusive environment for student-athletes.

The Coaching Enhancement Grant by the NCAA Division III aims to increase diversity in assistant coaching roles by providing financial support to member institutions. Over two years, selected schools receive $15,000 to cover salaries, requiring a matching contribution. This initiative encourages ethnic minority and gender representation, allowing up to 11 institutions to benefit annually, thus enhancing inclusivity in collegiate sports.

The North Central Branch John Henry Comstock Award recognizes one graduate student from each of the Entomological Society of America's six branches. This award promotes graduate-level entomology and encourages attendance at the ESA Annual Meeting. Benefits include an all-expense-paid trip to the national meeting, a $500 cash prize, and a certificate presented during the meeting. Eligibility includes current enrollment in a graduate entomology program or recent graduation.

The Virginia H. Glasson Charitable Trust Grant supports Christian charitable organizations and preferred beneficiaries. It funds projects in areas such as education, scientific research, religious activities, and arts and culture. Eligible applicants are nonprofit organizations recognized under section 501(c)(3) of the IRS tax code, located in states such as California, Colorado, Florida, Missouri, North Carolina, and Washington D.C. However, individuals cannot apply for funding.

The Growing Tribal Economies Through Forest Market Innovations grant program, initiated by First Nations Development Institute, aims to empower Tribes and Alaska Native Villages to engage in emerging markets that enhance forest health and resilience. With funding of $200,000 to $500,000 per grant, this initiative supports projects focusing on sustainability, innovation, and traditional knowledge. Eligible applicants are encouraged to develop forest products, certifications, and practices that contribute positively to biodiversity and ecosystem management.

The Colorado Trust offers event sponsorships aimed at supporting health equity initiatives in Colorado. Nonprofits with 501(c)(3) status can apply for funding up to $5,000 for fundraising and special events that align with the Trust's vision. The application schedule has been expanded to six cycles annually, providing more opportunities for organizations to seek support. This initiative reflects the Trust's commitment to ensuring all Coloradans have equal chances to lead healthy lives.

The Western SARE Farmer/Rancher Grants support agricultural producers in developing innovative, sustainable practices through research and outreach. Eligible applicants include farmers or ranchers who collaborate with technical advisors to implement projects focused on addressing specific agricultural needs. Grants can provide funding up to $25,000 for 1-2 producers and up to $29,900 for larger collaborations. The program aims to enhance profitability, environmental quality, and community well-being while sharing knowledge among producers.

The Mazamas is committed to exploring and preserving mountain environments in the Pacific Northwest through research grants. These grants support nonprofit research that aligns with the Mazamas’ mission, encouraging proposals from graduate and undergraduate students. Successful applicants often conduct field studies that enhance understanding of the region's natural features. Notably, the Mazamas also welcome innovative research ideas that may fall outside traditional grant guidelines, promoting a diverse range of scientific inquiry.

The TourWest Grants, funded by the National Endowment for the Arts, aim to support presenters and organizations in the Western region by providing flexible funding for touring artists. This competitive grant encourages community engagement and outreach, fostering collaboration between artists and local communities. It prioritizes accessibility to the performing arts, especially in underserved areas. Applicants must be tax-exempt organizations or local government units and demonstrate a commitment to community needs through their projects.

The Dunkin’ Prom Grant, provided by the Joy in Childhood Foundation, aims to bring joy to teenage patients unable to attend their own prom due to illness. By funding hospitals to host prom-like events, the program ensures these patients experience this significant milestone. Grants typically range from $20,000 to $50,000, supporting the creation of memorable events with themes, food, entertainment, and formal wear for the teens, making a positive impact in their lives.

The Lowe Fund Grant, established by the Lowe family in the 1960s and managed by The Denver Foundation, aims to support Colorado nonprofits focused on training and research related to developmental disabilities, including cerebral palsy. Eligible organizations must be 501(c)(3) nonprofits operating in Colorado, with an emphasis on those in rural areas. The fund particularly seeks initiatives that directly assist individuals with these disabilities, fostering effective treatments and advocacy.

The William B. O'Rourke Foundation offers grants primarily focused on enhancing vision care and educational services in Colorado. Eligible applicants include individuals and non-profits, with funding aimed at projects that cannot be financed through other sources. The Foundation emphasizes projects that promote eye health, develop training programs, and increase public awareness of vision services. Priority is given to applications that demonstrate matching funds from other sources, ensuring collaborative efforts in advancing vision care initiatives.

The Reisher Graduate Scholarship, offered by the Denver Foundation, supports alumni of the Reisher Scholars Program in pursuing advanced degrees in Colorado. This scholarship provides financial assistance for tuition, fees, and educational expenses, with award amounts ranging from $5,000 to $20,000. Applications are accepted in three cycles starting in Fall 2025, and eligibility requires prior funding from the Reisher Scholars Program and enrollment in a graduate program.

About NCRC

The National Community Reinvestment Coalition (NCRC) is a nationwide network of nearly 800 organizations and champions working for a Just Economy, where all Americans can build wealth and provide for their families with stability and dignity.

Our vision: To solve America’s historic racial and socio-economic wealth, income and opportunity divides. This vision is the foundation of the Just Economy Pledge.

NCRC Field Empowerment Fund (FEF) - Housing Counseling Services

The Field Empowerment Fund (FEF) empowers NCRC network members to level up established service lines.

The Housing Counseling Services series within FEF supports HUD-approved housing counseling agencies in driving homeownership, such as through pre-purchase counseling. In addition, the program builds agency knowledge on heirs’ property challenges to better equip first-time and low-income homebuying households with the know-how to retain intergenerational wealth.

In doing so, FEF-HCS aims to help underserved families begin their homeownership journey, with an additional goal of ensuring foresight into the long-term future of their home purchase.

The FEF-HCS series is funded in partnership with Key Bank and HSBC, and targets communities within the Key Bank and HSBC branch footprints.

Through these partnerships, $2.5 million in Key Bank geographies and $1.5 million in HSBC geographies has been allocated for the subgrants for direct-to-client housing counseling services that will be awarded in three rounds in the FEF-HCS track.

Funding Support

Awardee agencies will receive subgrants to support their housing counseling services to clients.

Knowledge Building

Awardee agencies will attend a training session on heirs’ property challenges and best practices, hosted by NCRC National Training Academy. Bolstering counselor knowledge on this topic will ensure that your agency is not only serving clients in their personal wealth-building journey now, but also helping them preserve that wealth in generations to come.

The ReFED Catalytic Grant Fund, managed by Refed Inc., supports innovative solutions to minimize food waste and reduce methane emissions, a cost-effective strategy for climate action. This fund prioritizes initiatives that enhance food recycling and improve supply chain efficiency in the beef and dairy sectors. By focusing on proven methods, the grant aims to accelerate impactful changes in the food system, ultimately fostering sustainable practices and collaborative efforts to combat food waste.

The Connecting Joy Grant, provided by the Joy in Childhood Foundation, aims to enhance the hospital experience for children battling illness through engaging gaming programs. This initiative supports children's hospitals and nonprofits by funding equipment, staffing, and connectivity, ensuring children can enjoy gaming at their bedside. With grants ranging from $25,000 to $150,000, the program focuses on offering joy and distraction, helping young patients cope with their hospital stays while facilitating connections with peers.