Best Addiction and Substance Abuse Grants in Missouri

The US Department of Health & Human Services, through the NIH, invites applications for innovative approaches to implement SBIRT/P for addressing alcohol, tobacco, and other drug use in adults facing health disparities. This funding opportunity encourages research that tests screening, brief interventions, and referrals for treatment or prevention services. Applications are due on specified deadlines from February 2024 through March 2027, fostering collaboration with healthcare and community partners to enhance public health outcomes.

The Youth Opportunities Program (YOP) aims to enhance community engagement and positive development for youth under 21 years old through public-private partnerships. Administered by the Missouri Department of Economic Development, YOP offers tax credits to eligible donors, facilitating funding for local projects that promote self-esteem and reduce youth violence, particularly in high-crime areas. With $6 million in credits available, YOP prioritizes initiatives that foster community-based solutions for youth.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

The Siletz Tribal Charitable Contribution Fund, established by the Confederated Tribes of Siletz Indians, has distributed over $16.3 million in grants since 1999. It supports charitable organizations and local governments in eleven Oregon counties, as well as Native American initiatives across the U.S. The fund prioritizes education, health, public safety, addiction prevention, housing, arts, and environmental preservation, ensuring the Tribe's commitment to community support and cultural heritage.

The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.

The BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program aims to combat the rising crisis of substance use and overdose deaths. This funding opportunity supports state, local, territorial, and tribal governments in implementing comprehensive responses, including law enforcement initiatives, prevention programs, and recovery services. Applications are due by October 1, 2026, providing a crucial chance to enhance community safety and health through targeted interventions.

The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

The NIH R25 program aims to enhance inclusivity in research education by supporting activities that encourage individuals from diverse backgrounds to pursue careers in substance use and addiction sciences. This initiative focuses on skills development courses and research experiences, particularly targeting underrepresented groups in biomedical and behavioral sciences. Applications are due by 5:00 PM local time of the applicant organization, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline.

The NIDA Mentored Clinical Scientist Development Program Award aims to foster research independence in clinician scientists by providing intensive supervised research training and career development in the field of substance use and substance use disorder. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submission for this essential funding opportunity.

The High Priority HIV and Substance Use Research funding opportunity aims to support innovative research that addresses the intersection of HIV and substance use. Researchers are encouraged to submit proposals that include a detailed research plan and preliminary data, exploring new avenues for prevention, treatment, and potential cures for HIV among people who use drugs. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.

The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.

The Cooperative Agreement to Support Activities Related to Analgesics, Anesthetics, and Addiction (U01) aims to enhance research in Anesthesia, Addiction Medicine, and Pain Medicine. It focuses on critical areas such as clinical trial endpoints for chronic pain, outcome measures in stimulant use disorders, and neurodevelopmental assessments in pediatric patients. The initiative encourages applicants to propose comprehensive, evidence-based plans to improve the prescribing of analgesic and anesthetic drug products, with multiple awards available.

The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) invites applications that address urgent research needs in substance use epidemiology and health services. This funding opportunity encourages pilot studies focusing on emerging drug issues, unexpected prescription drug abuse trends, and timely medical system challenges. Letters of Intent are recommended 30 days before the proposal deadline, emphasizing the necessity for rapid review and funding to address pressing scientific questions.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R21 Clinical Trial Optional) aims to fund projects that explore policies related to tobacco, alcohol, and cannabis in the U.S. The focus is on understanding how these policies affect usage and exposure among disadvantaged populations. Engaging community organizations is essential for promoting equity in cancer prevention. This initiative is crucial for advancing health equity and reducing disparities in substance use.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity grant aims to support research on policies affecting tobacco, alcohol, and cannabis use in the U.S. This initiative focuses on how these policies impact populations facing health disparities. Key components include engaging community organizations to advance equity in cancer prevention. Important deadlines for applications range from February 2025 to October 2027, providing opportunities for both standard and renewal submissions.

The NIDA Research Education Program (R25) aims to enhance the training of a workforce skilled in biomedical, behavioral, and clinical research, particularly regarding substance use disorders. This program supports educational activities that prepare clinicians and clinical researchers. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline. This initiative does not fund non-research-related clinical training.

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The NCDDG program supports innovative research aiming to discover and develop new treatments for mental disorders, including substance use and alcohol use disorders. This initiative encourages collaborations between academic and industry partners to advance neurostimulation techniques and drug/device development. Applicants are invited to submit proposals that focus on specific projects utilizing the U01 mechanism, with a clear emphasis on rationally designed candidate agents and cutting-edge technologies. Letters of Intent are encouraged 30 days prior to the submission deadline.

The National Cooperative Drug/Device Discovery/Development Groups (NCDDG) program invites applications to foster innovative research in treating mental disorders and substance use issues. This initiative promotes collaboration between academia and industry, supporting diverse, multidisciplinary projects aimed at developing rational therapies and neurostimulation techniques. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline to enhance project alignment with funding goals.

The Opioid Crisis Response Program Fellowship, offered by Equal Justice Works, addresses the opioid epidemic by mobilizing public interest lawyers to provide vital civil legal aid to underserved communities affected by Opioid Use Disorder. This two-year fellowship enables attorney fellows to advocate for clients' rights, reduce barriers to treatment, and enhance community education about legal impacts. Through collaboration with various stakeholders, the program aims to improve health outcomes and foster systemic change in the fight against this public health crisis.

The HEAL initiative aims to translate addiction research into practice to combat the opioid crisis and overdose events. It focuses on identifying barriers to reducing substance use and developing scalable, evidence-based interventions. Emphasizing recovery, prevention, and the integration of mental health, the initiative encourages collaboration among experts in various fields. Although applications are not currently solicited, potential applicants are urged to prepare for future opportunities to apply innovative solutions to enhance addiction treatment and prevention efforts.

Just One More Grant aims to transform lives by providing financial support to individuals and nonprofit organizations in the U.S. who are overcoming challenges like mental health issues, drug misuse, and educational barriers. The foundation encourages applications from those committed to personal growth and community support. Though current grants are paused for nonprofits, interested individuals with actionable plans are invited to apply. More information and past winners can be found on their website.

This NOFO invites applications for innovative research aimed at developing and implementing interventions to prevent and treat substance use disorders (SUDs) and overdose. It encourages studies that can rapidly advance candidate solutions towards regulatory approval or clinical use, while also addressing co-morbid SUDs. The initiative supports a wide range of research including basic, clinical, translational, and implementation strategies to tackle drug misuse and related health issues, such as HIV/AIDS.

The Rural Opioid Technical Assistance Centers program aims to provide essential training and technical assistance to combat opioid and stimulant misuse in rural areas. With 10 Regional Centers and a National Coordinating Office, the initiative focuses on high-quality prevention, treatment, and recovery support services for substance use disorders. This program anticipates awarding 11 new grants to enhance community health and safety in addressing polysubstance use challenges.

The National Institute on Drug Abuse is funding pilot and feasibility studies aimed at preparing for substance use and HIV prevention research trials. The program encourages innovative interventions for substance use disorders and HIV eradication, focusing on stakeholder collaboration and practical application. Projects may include assessment of service models, intervention development, and community engagement. This initiative is designed to fill critical research gaps and enhance partnerships, although applications are not currently being accepted.

The National Institute on Drug Abuse (NIDA) is launching a specialized entrepreneurship program aimed at life science researchers in the field of substance use disorders (SUD). This initiative will equip researchers with essential skills to transform their innovative ideas into viable products, focusing on aspects such as market evaluation, customer discovery, and intellectual property. The course will be delivered in a hybrid format to engage US-based SUD researchers effectively, fostering collaboration and advancing the field.