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Best Addiction and Substance Abuse Grants in Missouri

Looking for Addiction and Substance Abuse Grants in Missouri? Find the perfect grant for your nonprofit on Instrumentl.

114

Available grants

$39.5M

Total funding

$162.5K

Median grant

114 grants
$39.5M total
$162.5K median

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Filters

114 Results based on applied filters

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) (357458)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.
Cancer / Oncology Epidemiology & Public Health Aging / Gerontology +17 more

Cohort Studies of HIV/AIDS and Substance Use (U01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.
HIV / AIDS Addiction & Substance Use Disorders

United Way of Greater St. Louis: Targeted Fund

United Way Of Greater St Louis Inc
Private
Calhoun County, Illinois, Clinton County, Illinois +14 more
Up to US $100,000
The United Way of Greater St. Louis Targeted Funding aims to provide flexible, one-year grants to nonprofits addressing urgent community needs through emergency, emergent, or innovative approaches. Funding will focus on basic needs, health and wellness, crisis response, and more across 16 counties. Priority will be given to areas identified as having the greatest needs based on recent assessments, ensuring that support is directed where it is most needed.
Basic Human Needs Wellness & Healthy Living Crisis Intervention +12 more

Agility Grants

National Council on Problem Gambling Inc.
Corporate
United States
US $20,000 - US $40,000
Agility Grants, initiated by the National Council on Problem Gambling, aim to minimize gambling-related harm through funding nonprofit organizations for innovative prevention programs. These grants focus on addressing gaps in services and enhancing existing initiatives. Eligible applicants include U.S.-based 501(c)(3) organizations, with priority given to projects targeting at-risk populations. The program emphasizes community impact and requires evaluations to assess effectiveness, fostering collaboration and awareness within diverse communities affected by gambling.
Addiction & Substance Use Disorders

Perry County Youth Tax Board - Large Grant

Perry County - Missouri
State/Local Government
Perry County, Missouri
More than US $1,500
The Perry County Youth Tax Board oversees the disbursement of approximately $300,000 annually to support programs aimed at enhancing the health and well-being of youth under 18 in Perry County. The Large Grant funding assists organizations in developing their community initiatives, allowing applications for up to 20% of the previous year's tax revenue. This funding aims to strengthen efforts for youth betterment, with requests exceeding $2,000 considered.
Children’s Health & Pediatrics Youth Services Children’s Mental Health +4 more

Perry County Youth Tax Board - Small Grant

Perry County - Missouri
State/Local Government
Perry County, Missouri
Up to US $1,500
The Perry County Youth Tax Board offers small grants up to $1,500 to support programs that enhance the health and well-being of individuals under 18 in Perry County. Organizations can apply twice a year, promoting community betterment and collaboration for larger projects. With an annual budget of $300,000, these funds aim to improve the quality of life for local youth through various initiatives.
Children’s Health & Pediatrics Youth Services Addiction & Substance Use Disorders +4 more

Episcopal Presbyterian Health Trust Grant

St Louis Community Foundation
Private
Jefferson County, Missouri, Madison County, Illinois +4 more
Up to US $25,000
The Episcopal Presbyterian Health Trust Grant, managed by the St. Louis Community Foundation, focuses on enhancing health care access and addressing chronic diseases. Grants are awarded biannually, prioritizing maternal and infant health in the second cycle. Organizations are encouraged to submit one Letter of Intent (LOI) annually, ensuring their proposals align with the funding priorities to foster sustainable health solutions in the community.
Health Care Access & Delivery Preventative Healthcare Community Health Education +4 more

NAILBA Charitable Foundation Grant

Nailba Charitable Foundation
Private
United States
Unspecified amount
The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.
Basic Human Needs Youth Services Poverty Alleviation & Services +7 more

Chapman Foundation Grant

Alvah H And Wyline P Chapman Foundation
Private
United States
Unspecified amount
The Alvah H. and Wyline P. Chapman Foundation offers grants to support charitable, educational, and community-focused initiatives, primarily in Florida and Georgia. Eligible applicants must be IRS-recognized 501(c)(3) organizations. The foundation prioritizes projects that address children's welfare, education, multicultural understanding, substance abuse prevention, and homelessness. Grants typically do not exceed $15,000, and proposals must be endorsed by a Foundation Director. Interested parties should submit a Letter of Inquiry for consideration.
Community Culture & Heritage Education Homelessness Services +10 more

APA Foundation: Helping Hands Grants

American Psychiatric Association Foundation
Private
United States
Up to US $5,000
The APA Foundation's Helping Hands Grants provide up to $5,000 to medical schools for projects aimed at improving mental health education and assistance in under-served communities. Initiated in 2005, this program empowers medical students to lead initiatives that promote awareness of mental illness and encourage community service, particularly among minority populations. By partnering with community agencies, these projects foster a deeper interest in psychiatry while addressing critical mental health needs.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders

Veterans Treatment Court Program: Planning & Implementation Grant

US Department of Justice: Bureau of Justice Assistance
Federal Government
United States, United States Minor Outlying Islands
Up to US $950,000

FY25 Veterans Treatment Court Program

Executive Summary

This NOFO will support the implementation and enhancement of veterans treatment court (VTC) operations. VTCs connect veterans who come in contact with the justice system to treatment for substance use disorders (SUD), mental health disorders (MHD), co-occurring mental health and substance use disorders (MHSUD), post-traumatic stress disorder (PTSD), and traumatic brain injury (TBI). Funding supports service coordination, and recovery support services. VTCs integrate mandatory drug testing, incentives and sanctions, and transitional services in judicially supervised criminal court settings that have jurisdiction over veterans with behavioral health treatment needs. These courts aim to reduce recidivism and overdose fatalities, while increasing access to treatment and recovery support that leads to long-term recovery.

Category 1 supports the planning and implementation and/or launch of a VTC. These courts will support core capacity and provide critical behavioral health treatment, case management and coordinated judicial supervision, sanctions and incentives, and other supportive services, such as transitional housing, peer recovery services, relapse prevention and employment services, that can reduce recidivism.

Program Description

Planning and Implementation grants are available to eligible jurisdictions ready to commit to a 6- month planning phase followed by an implementation and/or launch of a VTC that supports core capacity and provides critical behavioral health treatment, case management and coordinated judicial supervision, sanctions and incentives, and other supportive services, such as transitional housing, peer recovery services, relapse prevention and employment services, that can reduce recidivism, including serving veterans who cannot or do not have access to Department of Veterans Affairs (VA) services

Military & Veterans Services Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders

NCRG Large Grant

International Center for Responsible Gaming
Private
United States
Up to US $187,500
The NCRG Large Grant, provided by the International Center for Responsible Gaming, supports high-quality research on gambling disorders and responsible gambling. Eligible applicants can request up to $75,000 annually for a maximum of 24 months, totaling $187,500. The grant emphasizes scientific rigor through its advisory board, ensuring only the best proposals receive funding. This initiative aims to advance understanding and treatment of gambling-related issues through peer-reviewed research.
Addiction & Substance Use Disorders

Bernau Family Foundation Grant

Bernau Family Foundation
Private
United States
Unspecified amount
The Bernau Family Foundation Grant aims to enhance individual lives and foster positive leadership through funding initiatives that provide long-term solutions. Grants are awarded to IRS-designated public charities or nonprofits, emphasizing projects that promote civic responsibility, education, and mentor programs. The foundation prioritizes smaller organizations that encourage meaningful community engagement and constructive change, ensuring a lasting impact on society.
Addiction & Substance Use Disorders Crime & Justice Civic Affairs +2 more

Schlink Foundation Grant (2026-09-26)

Albert G And Olive H Schlink Foundation
Private
United States
Unspecified amount
The Albert G. and Olive H. Schlink Foundation, established in 1966, has significantly impacted Ohio's nonprofit sector by increasing its annual grant distribution from an initial $500 to over $1.4 million in 2023. The Foundation prioritizes organizations with ties to Erie and Huron Counties and emphasizes thoughtful evaluation of all grant applications. With a focus on community needs, it continues to honor the founders' legacy while adapting to the evolving demands of local nonprofits.
Disability Care & Services Senior Services Aging / Gerontology +8 more

HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.
Epidemiology & Public Health Addiction & Substance Use Disorders Health Care Access & Delivery +2 more

Phased Large Awards for Comparative Effectiveness Research PCORI Funding Announcement -- Cycle 1 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $22,000,000
The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.
Addiction & Substance Use Disorders Mental Health & Psychiatric Diseases Cardiovascular Diseases & Systems +2 more

HEAL Initiative: Integrative Management of Chronic Pain and Opioid Use Disorder (OUD) for Whole Recovery: Health Systems

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.
Epidemiology & Public Health Addiction & Substance Use Disorders Health Care Access & Delivery +3 more

Jennie K. Scaife Charitable Foundation Grant

Jennie K Scaife Charitable Foundation Inc
Private
United States
Unspecified amount
The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.
Children’s Health & Pediatrics Women & Girl Services Addiction & Substance Use Disorders +2 more

Avant Garde Award for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000 - US $700,000
The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.
HIV / AIDS Addiction & Substance Use Disorders

TJX Foundation Grants

The Tjx Foundation Inc
Corporate
United States
Unspecified amount
The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.
Basic Human Needs Workforce Preparation & Job Readiness Domestic Violence +1 more

Hearst Foundation: Culture Grant

William Randolph Hearst Foundation
Private
United States
More than US $100,000
The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.
STEM / STEAM Education Art Education Artist Training & Development +6 more

Good Neighbor Citizenship Company Grants

State Farm Companies Foundation
Corporate
United States
Unspecified amount
State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.
Disaster Preparedness Disaster Relief / Humanitarian Aid Firefighting & Fire Prevention +13 more

Semnani Family Foundation Grants

Semnani Family Foundation
Private
Afghanistan, Bosnia and Herzegovina +20 more
Unspecified amount
The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.
Homelessness Services Food Access & Hunger Diseases & Conditions +14 more

Mutual of America's Community Partnership Award

Mutual Of America Foundation
Corporate
United States
Unspecified amount
The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.
All fields of work

O'Reilly Automotive Foundation Grant

O'Reilly Automotive Foundation Inc
Private
United States
Unspecified amount
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
Economic Services & Development Homelessness Services Food Access & Hunger +12 more

LabCorp Charitable Foundation Grants

Labcorp Charitable Foundation
Private
United States
Unspecified amount
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Education Community Services Health & Medicine +5 more

Spark Good: Strengthening Community - Local Grants

Wal-Mart Foundation
Corporate
United States
US $250 - US $5,000
The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.
Community Services

Addiction and Substance Abuse Grants in Missouri Highlights

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Grant Insights : Grant Funding Trends in Missouri

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Addiction and Substance Abuse Grants in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Addiction and Substance Abuse Grants in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Addiction and Substance Abuse Grants in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

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