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Best St. Louis Grants for Nonprofits in Missouri
Discover active funding opportunities in St. Louis Grants for Nonprofits. 35,000+ grants are available for a wide range of missions and programs with additional grants in Kansas City, Springfield, and Columbia
96
Available grants
$2.9M
Total funding
$10K
Median grant
96
grants
$2.9M
total
$10K
median
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Up to US $12,000
Capacity Building Grant - Comprehensive Organizational Assessment & Reports (COAR) Grant Program
Rolling deadline
The Capacity Building Grant - Comprehensive Organizational Assessment & Reports (COAR) Grant Program by the Marillac Mission Fund aims to enhance nonprofit infrastructure and leadership. This initiative supports organizationally-ready nonprofits by providing funding for core capacity building, fostering sustainable practices to better serve vulnerable populations in the St. Louis area. The program emphasizes organizational assessments to evaluate strengths and weaknesses, ultimately facilitating growth and positive change.
Marillac Mission Fund
US $5,000 - US $25,000
The Pettus Foundation Grants
Rolling deadline
The Pettus Foundation Grants focus on enhancing self-reliance and productivity in underserved communities through targeted funding in St. Louis. They support nonprofit initiatives in workforce development, youth development, and education, with a keen interest in early childhood education and job training programs. Applications are by invitation only, facilitated by the St. Louis Community Foundation, emphasizing robust governance and collaboration with multiple funding partners. Typical grants range from $5,000 to $25,000.
St Louis Community Foundation
Up to US $25,000
Episcopal Presbyterian Health Trust Grant
Applications due Jul 17, 2026
The Episcopal Presbyterian Health Trust Grant, managed by the St. Louis Community Foundation, focuses on enhancing health care access and addressing chronic diseases. Grants are awarded biannually, prioritizing maternal and infant health in the second cycle. Organizations are encouraged to submit one Letter of Intent (LOI) annually, ensuring their proposals align with the funding priorities to foster sustainable health solutions in the community.
St Louis Community Foundation
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Up to US $25,000
Marillac Mission Fund: Capacity Building Grant - Standard Capacity Building Grant (CBG) Program
Applications due Aug 2, 2026
The Marillac Mission Fund provides funding for capacity building grants aimed at enhancing the effectiveness of nonprofits focused on vulnerable populations. Eligible organizations must have a history of receiving MMF funding and be located in the St. Louis area. Grants can support various improvement activities including strategic planning and resource development, with a maximum award of $25,000 per year. This program seeks to empower nonprofits to better serve their communities and advocate for those in need.
Marillac Mission Fund
US $5,000 - US $30,000
Roblee Foundation Grant
Full proposal due Aug 4, 2026
The Roblee Foundation Grant supports initiatives that promote equity in race, ethnicity, and gender. It prioritizes funding for proposals that empower marginalized communities through women's issues, youth opportunities, and early childhood education. Grants are available for projects in the St. Louis area and Miami-Dade, FL. Applicants must consult with foundation staff before submission. The foundation focuses on early, catalytic, and movement-building approaches to create lasting change and improve lives.
Joseph H. and Florence A. Roblee Foundation
Up to US $15,000
Arts and Healing Initiative
Applications due Aug 15, 2026
The Arts and Healing Initiative aims to support arts, social service, and health organizations in implementing arts-based wellness programs. This initiative will enhance the healing process and improve the quality of life for individuals and their families in the St. Louis region. With a strong backing from the Arts and Education Council, the initiative continues a legacy of over $100 million in grants aimed at fostering community health through the arts.
Arts and Education Council of St. Louis
Unspecified amount
Dana Brown Charitable Trust Grant
Letter of inquiry due Aug 28, 2026
The Dana Brown Charitable Trust Grant supports organizations in the St. Louis area that aid financially disadvantaged children, focusing on health, education, and welfare. It encourages programs that expand children's knowledge of nature and wild animals. The Trust favors collaborative, high-impact projects and prioritizes immediate needs over long-term funding. Notably, individual grants are not awarded directly to individuals, and only one Letter of Intent is permitted per year.
Dana Brown Charitable Trust
Unspecified amount
Bayer Fund: Health & Wellness Grant Program
Full proposal due Sep 1, 2026
The Bayer Fund Health & Wellness Grant Program aims to support organizations that provide education and resources for patients and caregivers facing cancer and cardiovascular diseases. Grants focus on assisting communities, particularly the African American population, in managing these health issues. Funding covers educational services, disease awareness, and access to care, with all activities to commence post-funding decisions. Eligible organizations must hold a 501(c)(3) status and operate within 55 miles of Bayer sites.
Bayer Fund
US $75,000 - US $300,000
Pew Biomedical Scholars
Full proposal due Sep 3, 2026
The Pew Biomedical Scholars Program offers significant funding of $300,000 over four years to support early-career researchers in biomedical sciences. The program encourages innovative and impactful research that contributes to human health, requiring nomination from one of the 212 participating institutions. Candidates must hold a doctorate, run an independent lab as an assistant professor, and demonstrate exceptional promise. This program fosters collaboration and annual meetings for scholars to present their findings.
Pew Charitable Trusts
Up to US $25,000
Trio Foundation of St. Louis Grant
Applications due Sep 4, 2026
The Trio Foundation of St. Louis Grant aims to enhance community well-being and promote equity through its new funding framework. Established over two decades ago, the foundation focuses on empowering marginalized groups, particularly those facing discrimination based on race, gender, and socioeconomic status. The grant supports initiatives in women's economic empowerment, arts accessibility, and environmental justice, fostering authentic relationships with community partners to create lasting impact in the St. Louis region.
Trio Foundation of St. Louis
Up to US $100,000
United Way of Greater St. Louis Targeted Funding
Applications due Sep 27, 2026
The United Way of Greater St. Louis Targeted Funding aims to provide flexible, one-year grants to nonprofits addressing urgent community needs through emergency, emergent, or innovative approaches. Funding will focus on basic needs, health and wellness, crisis response, and more across 16 counties. Priority will be given to areas identified as having the greatest needs based on recent assessments, ensuring that support is directed where it is most needed.
United Way Of Greater St Louis Inc
US $10,000 - US $50,000
Charless Foundation Grant
Applications due Sep 29, 2026
The Charless Foundation, part of the St. Louis Community Foundation, aims to support charitable organizations that promote the health and wellness of Missouri senior citizens, especially in South St. Louis City. Starting in 2025, grantmaking will focus on housing assistance, including home repairs and modifications for older adults. Additionally, funding for food banks will be available, capped at $10,000 per site. Grants can range from $10,000 to $50,000 annually, depending on the applicant's history with the foundation.
St Louis Community Foundation
Up to US $500,000 in in-kind support
Neighborhood Assistance Program
Applications due Oct 3, 2026
The Neighborhood Assistance Program (NAP), administered by the Missouri Department of Economic Development, provides tax credits to incentivize donations for community projects. Aimed at enhancing community service, education, and revitalization, NAP offers up to $16 million in credits, with a maximum of $500,000 per project. Eligible applicants include nonprofits and businesses, while donors can receive credits up to 70% for their contributions. Attend the virtual workshop on April 1, 2025, to learn more about applying.
Missouri Department of Economic Development
US $10,000
PLTW Engineering - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Engineering - Program Expansion initiative aims to enhance STEM education by increasing access to Project Lead The Way (PLTW) programs in communities served by Burns & McDonnell. This partnership focuses on empowering students through real-world learning experiences, helping them develop essential skills for future careers. Starting in the 2026-2027 academic year, grants will support schools in expanding their existing PLTW Engineering programs to foster greater participation and engagement in STEM fields.
Project Lead The Way Inc
US $10,000
PLTW Gateway - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Gateway - New Program, in partnership with Burns & McDonnell, aims to enhance student engagement in STEM by providing teachers with essential resources and support. Starting in the 2026-2027 academic year, eligible schools can apply for grants to introduce and expand PLTW programs, fostering real-world skills through applied learning. This initiative targets schools with significant free and reduced-price lunch populations, promoting equity in education across various U.S. counties.
Project Lead The Way Inc
US $10,000
PLTW Gateway - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Gateway - Program Expansion initiative, led by Burns & McDonnell in partnership with Project Lead The Way (PLTW), aims to enhance STEM education by increasing access to PLTW programs for students in eligible communities. This program empowers students through real-world applied learning experiences, promoting essential skills for college and careers. Grants will support schools in expanding their existing PLTW Gateway programs starting in the 2026-2027 academic year, fostering a brighter future through education.
Project Lead The Way Inc
US $10,000
PLTW Launch - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Launch - New Program initiative, sponsored by Burns & McDonnell, aims to enhance STEM education by providing grants to eligible schools within specific U.S. counties. Schools must implement PLTW modules over two academic years, ensuring access to real-world learning experiences for students, particularly those from low-income backgrounds. This program emphasizes the importance of empowering educators and fostering student engagement in STEM fields to prepare them for future careers.
Project Lead The Way Inc
US $5,000
PLTW Launch - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Launch - Program Expansion initiative by Burns & McDonnell aims to enhance access to STEM education in U.S. schools. This program focuses on empowering students by providing real-world learning experiences and essential skills. Grants will support schools in expanding PLTW programs during the 2026-2027 academic year, benefiting students from underserved communities. By fostering a deeper understanding of STEM, the initiative seeks to inspire the next generation of innovators and problem solvers.
Project Lead The Way Inc
Up to US $7,000
Creley Memorial Conservation Grant
Applications due Mar 31, 2027
The Creley Memorial Conservation Grant, established by the St. Louis Audubon Society, supports bird conservation and education projects in the St. Louis region. Funded by a generous family donation, the grant aims to strengthen collaborations and initiate partnerships that promote bird conservation. With an estimated $7,000 available for the 2025 grant cycle, this initiative reflects SLAS's commitment to fostering awareness and understanding of birds and their habitats, helping communities make informed ecological decisions.
ST LOUIS AUDUBON SOCIETY
Up to US $5,000
Ava’s Grace Scholarship
Applications due Apr 15, 2027
Ava’s Grace Scholarship, founded in 2010, provides vital educational support to students with incarcerated parents or caregivers in Missouri and parts of Illinois. Offering scholarships up to $5,000 annually, it renews through graduation. This initiative promotes hope and community, transforming lives through education. Eligible applicants must demonstrate financial need and maintain a minimum GPA of 2.0, while also planning to pursue an accredited degree. This program, part of The Scholarship Foundation of St. Louis, aims to foster a brighter future.
The Scholarship Foundation of St. Louis
Up to US $12,000
BJC Scholars Fund Scholarship
Applications due Apr 15, 2027
The BJC Scholars Fund Scholarship, backed by BJC HealthCare, aims to support high school seniors from specific Missouri and Illinois counties pursuing higher education. Eligible students can receive up to $12,000 per academic year, renewable for up to ten semesters. This initiative addresses community needs highlighted by the Ferguson Commission, promoting educational opportunities for youth in the regions served by BJC hospitals, which are known for their commitment to healthcare excellence.
The Scholarship Foundation of St. Louis
Up to US $5,000
Insuring Rural Communities Scholarship
Applications due Apr 15, 2027
The Insuring Rural Communities Scholarship supports students from rural Missouri and Illinois, offering renewable scholarships up to $5,000. Funded by Valley Insurance Agency Alliance and Travelers Foundation, it aims to assist those pursuing degrees in healthcare, information technology, or risk management. Eligible applicants must be permanent residents of non-metropolitan areas, enrolled in accredited programs, and demonstrate significant financial need. This initiative enhances academic and career success in underserved communities.
The Scholarship Foundation of St. Louis
Unspecified amount
Marilyn and Morton Werner Egality Scholarship Fund
Applications due Apr 15, 2027
The Marilyn and Morton Werner Egality Scholarship Fund honors the legacy of its namesakes by supporting students committed to civic engagement and systemic change. Open to residents of the St. Louis metropolitan area, this scholarship prioritizes individuals with a proven record of leadership and community involvement. Award amounts reach up to $10,000 annually for graduate students and $6,000 for undergraduates, with funding available for up to five years. This initiative aims to empower the next generation of leaders in policy and public service.
The Scholarship Foundation of St. Louis
Up to US $15,000
New Era Scholarship
Applications due Apr 15, 2027
The New Era Scholarship, offered by The Scholarship Foundation of St. Louis, provides up to $12,000 annually for eligible students from select youth development agencies and high schools in the St. Louis area. This renewable scholarship supports those aiming to attend accredited colleges or technical schools in Missouri and select Illinois institutions. Applicants must demonstrate financial need and meet academic criteria, making this an essential opportunity for local high school seniors.
The Scholarship Foundation of St. Louis
US $50,000 - US $1,500,000
Safety Net Funding
Applications due Apr 17, 2027
United Way of Greater St. Louis
Our Mission: The United Way of Greater St. Louis mission is to mobilize the community with one goal in mind – helping people live their best possible lives. We unite people, resources and funding to help build strong and equitable communities where everyone can thrive.
Safety Net
United Way’s Safety Net is a collaborative network of agencies that deliver an array of essential direct services to address the region’s most pressing needs, helping families and individuals remain and work toward stability. Safety Net agencies provide direct services that address basic, urgent needs – such as access to food and housing— as well as supports that help move individuals and families toward stability, including education, health and well-being, workforce access, and financial mobility.
Safety Net Funding
United Way of Greater St. Louis is now accepting applications for its Safety Net Funding cycle and invites all eligible agencies across its 16-county region in Missouri and Illinois, including those not currently receiving United Way funding, to apply. United Way equips 160 local nonprofits with vital funding and training resources to support measurable impact across its five impact areas. Organizations selected will receive a three-year contract and become part of the UWGSL member agency network.
United Way’s Impact Areas
- Basic Needs
- Community Stability and Crisis Response
- Early Childhood and Youth Success
- Health and Wellbeing
- Jobs and Financial Mobility
While needs are great across the five impact areas, United Way will use data derived from its landscape analysis of community needs to inform how service areas will be prioritized to ensure the region has access to a strong and resilient network as needs arise.
United Way Of Greater St Louis Inc
Unspecified amount
ECF of The Boeing Company: St. Louis Missouri Chapter Grant Program
Applications due Jun 30, 2027
The Employees Community Fund (ECF) of The Boeing Company supports charitable organizations in the St. Louis area through grants focused on Health and Human Services, Education, Arts & Culture, and Civic Engagement. Applications for 2024 will be accepted from April 1 to June 30, with odd-numbered years prioritizing health initiatives. ECF has invested over $165 million in the community, empowering employees to make a significant impact through collaborative giving.
Employees Community Fund Of The Boeing Company
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Grant Insights : St. Louis Grants for Nonprofits
Grant Availability
How common are grants in this category?
Uncommon — grants in this category are less prevalent than in others.
96 St. Louis grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.
16 St. Louis grants for nonprofits over $25K in average grant size
7 St. Louis grants for nonprofits over $50K in average grant size
24 St. Louis grants for nonprofits supporting general operating expenses
80 St. Louis grants for nonprofits supporting programs / projects
900+ Grants on Instrumentl focused on Education - K through 12
800+ Grants on Instrumentl focused on Academic Success & Enrichment
Grant Deadline Distribution
Over the past year, when are grant deadlines typically due for St. Louis grants for Nonprofits?
Most grants are due in the fourth quarter.
Q1
21.1%
Q2
25.9%
Q3
23.5%
Q4
29.4%
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