Upcoming Webinar
How Funders Feel About AI, and What Keeps Them Saying Yes.
Wed, Oct 14 @ 2PM ET

Skip to main content
Main content

Best Cape Girardeau County Grants for Nonprofits in Missouri

Looking for grants for 501(c)(3) nonprofit organizations working in Cape Girardeau County? Find the perfect grant for your nonprofit on Instrumentl.

44

Available grants

$1M

Total funding

$12.8K

Median grant

44 grants
$1M total
$12.8K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

AI summary from publicly available grant information

Unspecified amount

Community Possible Grant Program: Play, Work, & Home Grants

Rolling deadline
The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.
US Bancorp Foundation

Unspecified amount

Costco Foundation Youth and Health Grants in Missouri

Rolling deadline
Nonprofit 501(c)(3) organizations in Cape Girardeau County, Missouri that support children, education, or health and human services may be eligible for charitable contributions to their programs. Costco Foundation considers monetary requests only, reviewing applications within 4–6 weeks and prioritizing demonstrated community need, measurable outcomes, collaboration, and a broad base of financial support.
Costco Wholesale Corporation

Unspecified amount

Creag Foundation Grants for Cape Girardeau Nonprofits

Rolling deadline
Focused on innovative human services, 501(c)(3) nonprofits in Cape Girardeau County, Missouri can seek funding from Creag Foundation for new approaches to social problems. Organizations with at least one year of 501(c)(3) status, including smaller or evolving programs, may submit a letter of inquiry for invitation-only grant consideration.
Creag Foundation

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Up to US $15,000

Youth Programs Funding for Nonprofits from DanPaul Foundation

Rolling deadline
Nonprofit 501(c)(3) organizations serving youth through education, health, development, or welfare programs can apply for up to US $15,000 from the DanPaul Foundation. Focus areas include early childhood development, child welfare, homelessness, poverty, refugee enrichment, and environmental education, and may benefit Cape Girardeau County, Missouri nonprofits working with children and youth.
The Dan Paul Foundation

Up to US $300,000

Draper Richards Kaplan Social Impact Grants

Rolling deadline
Cape Girardeau County, Missouri nonprofits and impact-first social enterprises tackling social or environmental challenges can access funding through Draper Richards Kaplan Foundation; awards up to US $300,000 over three years. Early-stage, scalable organizations serving underserved communities in the U.S. or globally may receive capital plus intensive capacity-building and community support.
Draper Richards Kaplan Foundation

Up to US $100,000

Tech-Enabled Social Impact Grants from Cisco

Rolling deadline
Nonprofit and NGO programs using technology for crisis response, education access, or economic empowerment, including those in Cape Girardeau County, Missouri, can apply for Cisco Systems Foundation’s Global Impact Cash Grants, offering up to US $100,000. Eligible organizations must primarily serve economically underserved communities and keep overhead at or below 25 percent.
Cisco Systems Foundation

More than US $100,000

Social Service Funding for Nonprofits from Hearst Foundation

Rolling deadline
U.S. 501(c)(3) nonprofits with strong, direct-service social programs can seek more than US $100,000 to expand proven efforts that reduce chronic poverty and strengthen families. With a mission to improve lives nationwide, William Randolph Hearst Foundation provides program, capital, and general operating support, which may benefit larger Cape Girardeau County, Missouri organizations meeting its scale and impact criteria.
William Randolph Hearst Foundation

Unspecified amount

Health and Education Grants for Nonprofits from Labcorp Charitable Foundation

Rolling deadline
Nonprofit 501(c)(3) organizations, including those serving Cape Girardeau County, Missouri, can seek funding for health, education, and community-focused programs from the Labcorp Charitable Foundation. Grants may support food pantries, healthcare and patient services for underserved populations, STEM programming, and initiatives promoting healthy lifestyles through medical research and screenings.
Labcorp Charitable Foundation

Unspecified amount

Michael & Susan Dell Foundation Support

Rolling deadline
Nonprofits and social enterprises working on education, children’s health, or family economic stability in Cape Girardeau County, Missouri may be eligible for more than US $50,000 to support or scale projects. With a mission to improve outcomes for urban low-income youth, Michael & Susan Dell Foundation funds organizations serving children and families in the U.S., India, and South Africa.
Michael & Susan Dell Foundation

Unspecified amount

Roche Corporate Donations and Philanthropy (CDP)

Rolling deadline
Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.
La Roche, Inc.

Unspecified amount

Humanitarian Health Funding for Nonprofits from Semnani Family Foundation

Rolling deadline
Nonprofit organizations providing health, education, or humanitarian aid can seek support for programs serving marginalized communities, including work that reaches Cape Girardeau County, Missouri. With a mission to empower vulnerable populations worldwide, Semnani Family Foundation provides grants for health care access, disaster relief, women and children’s services, literacy, and related human and social services.
Semnani Family Foundation

Unspecified amount

Sidney Stern Memorial Trust Grant

Rolling deadline
The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.
Sidney Stern Memorial Trust

Unspecified amount

Bank of America Community Development Grants

Rolling deadline
Nonprofit 501(c)(3) organizations in Cape Girardeau County, Missouri seeking support for community development, basic needs, workforce readiness, or cultural programming may be eligible for grants from Bank of America Charitable Foundation. Funding can support housing, hunger relief, workforce education, neighborhood preservation, arts and culture, environmental initiatives, and diversity and inclusion efforts in low- and moderate-income communities.
Bank Of America Charitable Foundation Inc

Unspecified amount

Community Service Grants for Nonprofits from Robinson Foundation

Applications due Oct 15, 2026
Nonprofit 501(c)(3) organizations serving communities in the Southern region can seek Robinson Foundation funding for programs in areas like children and families, poverty relief, education, health, disaster relief, and veterans’ issues. Cape Girardeau County, Missouri nonprofits with at least three years of activity and single-year project needs may be eligible.
Robinson Foundation

Unspecified amount

Cape Girardeau Basic Needs Funding via TJX Foundation

Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations in Cape Girardeau County, Missouri that provide basic needs, youth enrichment, workforce readiness, or domestic violence safety services can apply for The TJX Foundation’s grants. Eligible groups must be within 15 miles of a TJX location, meet mission and nondiscrimination criteria, and complete an eligibility questionnaire and invited application process.
The Tjx Foundation Inc

US $5,000 - US $10,000

Lawrence Foundation Grant

Applications due Nov 1, 2026
The Lawrence Foundation is a private family foundation established in 2000, dedicated to granting funds for environmental and human services causes. Eligible organizations include 501(c)(3) nonprofits and public schools, with grants typically ranging from $5,000 to $10,000. The foundation supports unrestricted grants for various projects, including disaster relief and environmental programs, but does not fund individuals or for-profit entities. Applications are evaluated based on alignment with the foundation's priorities.
Lawrence Foundation

US $250 - US $5,000

Spark Good: Strengthening Community - Local Grants

Applications due Nov 30, 2026
The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.
Wal-Mart Foundation

US $5,000 - US $25,000

Dr Scholl Foundation Community Grants in Missouri

Letter of inquiry due Feb 1, 2027
Nonprofit 501(c)(3) organizations can seek US $5,000 - US $25,000 for program support in education, social services, health care, civic and cultural, or environmental work, including those serving Cape Girardeau County, Missouri. Grants from Dr Scholl Foundation help U.S. nonprofits fund one-year projects that improve communities and quality of life.
Dr Scholl Foundation

More than US $50,000

Cape Girardeau Conservation Funding via Couch Foundation

Letter of inquiry due Mar 27, 2027
Wildlife conservation 501(c)(3) nonprofits in Cape Girardeau County, Missouri can seek the Storytelling Grant to share the impact of their work through compelling media and narratives. With a mission to support preservation, education, and wellness, Jesse W Couch Charitable Foundation provides more than US $50,000 to help tell these community-changing stories.
Jesse W Couch Charitable Foundation

Up to US $15,000

Cape Girardeau Education Funding via Scholarship Foundation

Applications due Apr 15, 2027
Graduating high school seniors in the St. Louis metropolitan area, including eligible Big Brothers Big Sisters participants in Cape Girardeau County, Missouri, can receive up to US $15,000 annually for college or technical education. The Scholarship Foundation of St. Louis supports students in partner schools and youth programs attending accredited nonprofit institutions in Missouri and select Illinois colleges.
The Scholarship Foundation of St. Louis

Unspecified amount

O'Reilly Automotive Foundation Grants for Missouri Nonprofits

Applications due Apr 15, 2027
O’Reilly Automotive Foundation provides Cape Girardeau County, Missouri nonprofits with project, general operating, and capital support for community-focused programs. U.S.-based 501(c)(3) organizations serving local communities where O’Reilly Auto Parts operates may be eligible, especially those addressing economic stability, workforce development, health and social services, or disaster relief for underserved individuals and families.
O'Reilly Automotive Foundation Inc

Up to US $12,000

Scholarship Funding for Students from Scholarship Foundation

Applications due Apr 15, 2027
Low-income students in Cape Girardeau County, Missouri pursuing their first technical, associate, or bachelor’s degree at an accredited nonprofit college can receive up to US $12,000 annually for postsecondary education. Grants from The Scholarship Foundation of St. Louis support active participants in partner youth development agencies, including Big Brothers Big Sisters of Eastern Missouri.
The Scholarship Foundation of St. Louis

US $5,000 - US $30,000

Community Ties Giving Program: Annual Local Grants

Applications due Apr 30, 2027
The Community Ties Giving Program by Union Pacific Foundation offers local grants aimed at enhancing community well-being through diverse funding priorities. These include safety initiatives, workforce development, community vitality, and environmental sustainability. The program emphasizes supporting organizations that promote diversity, equity, and inclusion, aiming to create impactful projects that resonate with Union Pacific's heritage and mission. Eligible applicants must be nonprofit organizations serving Union Pacific communities and demonstrate a clear need and capacity to deliver effective programming.
Union Pacific Foundation

US $30,000 - US $350,000

Chick Fil A Foundation Support for Youth

Applications due May 1, 2027
Nonprofit 501(c)(3) organizations in Cape Girardeau County, Missouri working on youth education, family services, hunger, housing, or environmental stewardship may be eligible for grants from Chick Fil A Foundation. The True Inspiration Awards provide US $30,000 - US $350,000 for programs serving underserved youth, their families, and local communities in the U.S., Canada, Puerto Rico, and Singapore.
Chick Fil A Foundation Inc

Up to US $3,000

Community Foundation of the Ozarks Support for Inclusion

Applications due May 6, 2027
Nonprofit 501(c)(3) organizations, government entities, school districts, and tax-exempt faith-based groups in Cape Girardeau County, Missouri can apply for grants up to US $3,000 to advance diversity, equity, inclusion, and belonging. Grants from Community Foundation of the Ozarks help cover leadership development, community engagement, and event expenses that promote visible representations of belonging.
Community Foundation of the Ozarks Inc.

Unspecified amount

Community Partnership Funding for Nonprofits from Mutual of America Foundation

Applications due Jul 1, 2027
Grants from Mutual of America Foundation help Cape Girardeau County, Missouri nonprofits that lead strong cross-sector community partnerships. Eligible 501(c)(3) organizations anywhere in the U.S. that collaborate with public, private, or social sector partners to address significant social issues and model replicable, high-impact solutions may be recognized through the annual Community Partnership Award competition.
Mutual Of America Foundation

US $5,000 - US $250,000

Gupta Family Foundation Human Services Grants

Applications due Jul 31, 2027
Nonprofit organizations providing poverty alleviation, human services, disability support, or disaster relief can apply for Gupta Family Foundation grants, with awards from US $5,000 - US $250,000. Grants from Gupta Family Foundation help Cape Girardeau County, Missouri nonprofits that meet its revenue, mission alignment, and non-sectarian criteria, including eligible 501(c)(3)s and qualifying foreign entities.
Gupta Family Foundation

Showing 27 of 44 results.

Sign up to see the full list

Cape Girardeau County Grants for Nonprofits Highlights

Looking for Cape Girardeau County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Cape Girardeau County grants recommended for your specific programs.

Grant Insights : Grant Funding Trends in Missouri

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Cape Girardeau County Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Cape Girardeau County Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Cape Girardeau County Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

Related Grants in Missouri

Browse Grants by Cities within Missouri

Browse Grants by Counties within Missouri

Adair County Andrew County Atchison County Audrain County Barry County Barton County Bates County Benton County Bollinger County Boone County Buchanan County Butler County Caldwell County Callaway County Camden County Carroll County Carter County Cass County Cedar County Chariton County Christian County Clark County Clay County Clinton County Cole County Cooper County Crawford County Dade County Dallas County Daviess County DeKalb County Dent County Douglas County Dunklin County Franklin County Gasconade County Gentry County Greene County Grundy County Harrison County Henry County Hickory County Holt County Howard County Howell County Iron County Jackson County Jasper County Jefferson County Johnson County Knox County Laclede County Lafayette County Lawrence County Lewis County Lincoln County Linn County Livingston County Macon County Madison County Maries County Marion County McDonald County Mercer County Miller County Mississippi County Moniteau County Monroe County Montgomery County Morgan County New Madrid County Newton County Nodaway County Oregon County Osage County Ozark County Pemiscot County Perry County Pettis County Phelps County Pike County Platte County Polk County Pulaski County Putnam County Ralls County Randolph County Ray County Reynolds County Ripley County Saline County Schuyler County Scotland County Scott County Shannon County Shelby County St. Charles County St. Clair County Ste. Genevieve County St. Francois County St. Louis City St. Louis County Stoddard County Stone County Sullivan County Taney County Texas County Vernon County Warren County Washington County Wayne County Webster County Worth County Wright County