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Best St. Clair County Grants for Nonprofits in Missouri
Looking for grants for 501(c)(3) nonprofit organizations working in St. Clair County, Missouri? Find the perfect grant for your nonprofit on Instrumentl
30+
Available grants
$1.2M
Total funding
$16.3K
Median grant
30+
grants
$1.2M
total
$16.3K
median
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Last updated: June 8, 2026. Next update: July 5, 2026.
Unspecified amount
Community Possible Grant Program: Play, Work, & Home Grants
Rolling deadline
The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.
US Bancorp Foundation
Up to US $100,000
Global Impact Cash Grants
Rolling deadline
The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.
Cisco Systems Foundation
Unspecified amount
LabCorp Charitable Foundation Grants
Rolling deadline
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Labcorp Charitable Foundation
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Unspecified amount
Roche Corporate Donations and Philanthropy (CDP)
Rolling deadline
Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.
La Roche, Inc.
Unspecified amount
Semnani Family Foundation Grants
Rolling deadline
The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.
Semnani Family Foundation
Unspecified amount
Sidney Stern Memorial Trust Grant
Rolling deadline
The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.
Sidney Stern Memorial Trust
Unspecified amount
The Bank of America Foundation Sponsorship Program
Rolling deadline
The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.
Bank Of America Charitable Foundation Inc
US $5,000 - US $250,000
Gupta Family Foundation Grant
Applications due Aug 31, 2026
The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.
Gupta Family Foundation
More than US $50,000
J.W. Couch Foundation Grant
Applications due Sep 25, 2026
The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.
Jesse W Couch Charitable Foundation
Unspecified amount
Ozarks Health Advocacy Foundation Grants
Letter of inquiry due Sep 30, 2026
The Ozarks Health Advocacy Foundation Grants prioritize the health needs of children in Southwest Missouri, aiming to support nonprofit organizations that address critical physical, mental, and dental health issues. With a commitment to improving the lives of young people, the foundation provides essential funding to ensure that no child suffers from health conditions due to financial constraints. Together, we can create a healthier future for our youth, enabling them to thrive and reach their full potential.
Ozarks Health Advocacy Foundation
Unspecified amount
Robinson Foundation Grant
Applications due Oct 15, 2026
The Robinson Foundation Grant, established in 2016, aims to alleviate hardships faced by individuals and communities, demonstrating God's love through charitable contributions. As a family-operated foundation, it focuses on creating meaningful, long-term impacts in various areas including animal welfare, education, and disaster relief. Organizations eligible for funding must be 501(c)(3) public charities. The foundation prioritizes fiscally responsible projects with the potential for tangible results, while not supporting capital projects.
Robinson Foundation
Unspecified amount
Dudley T. Dougherty Foundation Grant
Applications due Oct 31, 2026
The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.
Dudley T Dougherty Foundation Inc
Unspecified amount
TJX Foundation Grants
Letter of inquiry due Oct 31, 2026
The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.
The Tjx Foundation Inc
US $20,000
PLTW Engineering - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Engineering - New Program, supported by Burns & McDonnell, aims to empower U.S. students through STEM education. By offering at least one PLTW Engineering course in the 2026-2027 academic year, schools can enhance their curriculum and foster critical skills. This initiative not only increases access to valuable programs but also prepares students for future challenges in college and careers, ensuring they thrive in an evolving world.
Project Lead The Way Inc
US $10,000
PLTW Engineering - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Engineering - Program Expansion initiative aims to enhance STEM education by increasing access to Project Lead The Way (PLTW) programs in communities served by Burns & McDonnell. This partnership focuses on empowering students through real-world learning experiences, helping them develop essential skills for future careers. Starting in the 2026-2027 academic year, grants will support schools in expanding their existing PLTW Engineering programs to foster greater participation and engagement in STEM fields.
Project Lead The Way Inc
US $10,000
PLTW Gateway - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Gateway - New Program, in partnership with Burns & McDonnell, aims to enhance student engagement in STEM by providing teachers with essential resources and support. Starting in the 2026-2027 academic year, eligible schools can apply for grants to introduce and expand PLTW programs, fostering real-world skills through applied learning. This initiative targets schools with significant free and reduced-price lunch populations, promoting equity in education across various U.S. counties.
Project Lead The Way Inc
US $10,000
PLTW Gateway - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Gateway - Program Expansion initiative, led by Burns & McDonnell in partnership with Project Lead The Way (PLTW), aims to enhance STEM education by increasing access to PLTW programs for students in eligible communities. This program empowers students through real-world applied learning experiences, promoting essential skills for college and careers. Grants will support schools in expanding their existing PLTW Gateway programs starting in the 2026-2027 academic year, fostering a brighter future through education.
Project Lead The Way Inc
US $10,000
PLTW Launch - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Launch - New Program initiative, sponsored by Burns & McDonnell, aims to enhance STEM education by providing grants to eligible schools within specific U.S. counties. Schools must implement PLTW modules over two academic years, ensuring access to real-world learning experiences for students, particularly those from low-income backgrounds. This program emphasizes the importance of empowering educators and fostering student engagement in STEM fields to prepare them for future careers.
Project Lead The Way Inc
US $5,000
PLTW Launch - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Launch - Program Expansion initiative by Burns & McDonnell aims to enhance access to STEM education in U.S. schools. This program focuses on empowering students by providing real-world learning experiences and essential skills. Grants will support schools in expanding PLTW programs during the 2026-2027 academic year, benefiting students from underserved communities. By fostering a deeper understanding of STEM, the initiative seeks to inspire the next generation of innovators and problem solvers.
Project Lead The Way Inc
Unspecified amount
Ameriprise Community Grants
Applications due Jan 15, 2027
Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.
Ameriprise Financial
Unspecified amount
Hansen Family Foundation Grant
Applications due Mar 23, 2027
The Hansen Family Foundation Grant seeks to empower organizations that uphold the American values of life, liberty, and the pursuit of happiness. Focused on diverse causes like children, education, animals, environmental conservation, humanitarian efforts, and arts, the foundation is committed to supporting initiatives that create positive change. Eligible applicants must be 501(c)(3) nonprofits, while political campaigns and organizations with high budgets or overheads are ineligible. This grant fosters impactful contributions to society.
Hansen Family Foundation
Up to US $90,000
Arts and Culture Program Support Grantmaking Program
Applications due Apr 10, 2027
The Arts and Culture Program Support Grant aims to enrich communities through arts funding for nonprofit organizations. Supported by local hotel/motel tax collections, this program offers up to $10,000 per agency, focusing on projects that advance arts advocacy, improve access, and enhance community engagement. Organizations in a 27-county service area are eligible, with emphasis on collaborative and outreach projects, particularly for youth and seniors. Grant recipients must adhere to non-discrimination policies.
Community Foundation of the Ozarks Inc.
Up to US $5,000
Ava’s Grace Scholarship
Applications due Apr 15, 2027
Ava’s Grace Scholarship, founded in 2010, provides vital educational support to students with incarcerated parents or caregivers in Missouri and parts of Illinois. Offering scholarships up to $5,000 annually, it renews through graduation. This initiative promotes hope and community, transforming lives through education. Eligible applicants must demonstrate financial need and maintain a minimum GPA of 2.0, while also planning to pursue an accredited degree. This program, part of The Scholarship Foundation of St. Louis, aims to foster a brighter future.
The Scholarship Foundation of St. Louis
Up to US $15,000
New Era Scholarship
Applications due Apr 15, 2027
The New Era Scholarship, offered by The Scholarship Foundation of St. Louis, provides up to $12,000 annually for eligible students from select youth development agencies and high schools in the St. Louis area. This renewable scholarship supports those aiming to attend accredited colleges or technical schools in Missouri and select Illinois institutions. Applicants must demonstrate financial need and meet academic criteria, making this an essential opportunity for local high school seniors.
The Scholarship Foundation of St. Louis
Up to US $15,000
Nursing Scholarship Grants
Applications due Apr 15, 2027
The Deaconess Foundation offers Nursing Scholarship Grants aimed at supporting local students pursuing nursing degrees with demonstrated financial need. This program reflects the foundation's mission to enhance community health in Eastern Missouri and Southern Illinois. Grants are administered in partnership with the Scholarship Foundation of St. Louis and the St. Louis American Foundation. Eligible students must be working towards an accredited nursing degree and demonstrate significant financial need, among other criteria.
Deaconess Foundation
US $30,000 - US $350,000
True Inspiration Awards
Applications due May 1, 2027
The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.
Chick Fil A Foundation Inc
Up to US $3,000
Inclusion & Belonging Grant Program
Applications due May 5, 2027
The Inclusion & Belonging Grant Program by the Community Foundation of the Ozarks aims to promote diversity, equity, and inclusion in local communities. With $40,000 available, grants up to $3,000 support nonprofits, government entities, and schools in ensuring representation and engaging diverse voices in leadership. Applications are accepted anytime until funds are exhausted, fostering equitable opportunities for community involvement and event visibility in the Ozarks.
Community Foundation of the Ozarks Inc.
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Last updated: June 8, 2026. Next update: July 5, 2026.
Top Searched St. Clair County Grants for Nonprofits
Grant Insights : Grant Funding Trends in Missouri
Average Grant Size
What's the typical amount funded for Missouri?
Grants are most commonly $100,181.
$100,181
Total Number of Grants
What's the total number of grants in St. Clair County Grants for Nonprofits year over year?
In 2024, funders in Missouri awarded a total of 20,179 grants.
2022 39,922
2023 39,688
2024 20,179
Top Grant Focus Areas
Among all the St. Clair County Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.
1. Philanthropy, Voluntarism & Grantmaking Foundations
2. Education
3. Human Services
Funding Over Time
How is funding for St. Clair County Grants for Nonprofits changing over time?
Funding has increased by -61.86%.
2022 $4,698,402,122
2023
$5,287,874,816
12.55%
2024
$2,016,605,547
-61.86%
Missouri Counties That Receive the Most Funding
How does grant funding vary by county?
St Louis County, Jackson County, and St Louis City receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| St Louis County | $1,060,800,664 |
| Jackson County | $493,752,997 |
| St Louis City | $372,479,568 |
| Greene County | $134,480,889 |
| Cole County | $77,030,794 |
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