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Best St. Louis city Grants for Nonprofits in Missouri
Discover active funding opportunities in St. Louis city Grants for Nonprofits. 34,000+ grants are available for a wide range of missions and programs with additional grants in St. Louis County, Jackson County, and St. Charles County
96
Available grants
$2.9M
Total funding
$10K
Median grant
96
grants
$2.9M
total
$10K
median
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Up to US $100,000
Global Impact Cash Grants
Rolling deadline
The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.
Cisco Systems Foundation
Unspecified amount
LabCorp Charitable Foundation Grants
Rolling deadline
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Labcorp Charitable Foundation
Unspecified amount
Sidney Stern Memorial Trust Grant
Rolling deadline
The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.
Sidney Stern Memorial Trust
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Up to US $5,000
Disaster Relief Funding for Neighborhood Associations Grant
Applications due Jul 30, 2026
The St. Louis Community Foundation offers non-competitive grants of $5,000 to Neighborhood Associations in St. Louis City, St. Louis County, and Madison County, Illinois, to support their response to community needs following the 2025 tornado. These funds can be utilized for various services, including food, shelter, and home repair. Organizations must be 501(c)3 compliant to qualify, ensuring impactful assistance for vital community resources.
St Louis Community Foundation
US $5,000 - US $30,000
Roblee Foundation Grant
Full proposal due Aug 4, 2026
The Roblee Foundation Grant supports initiatives that promote equity in race, ethnicity, and gender. It prioritizes funding for proposals that empower marginalized communities through women's issues, youth opportunities, and early childhood education. Grants are available for projects in the St. Louis area and Miami-Dade, FL. Applicants must consult with foundation staff before submission. The foundation focuses on early, catalytic, and movement-building approaches to create lasting change and improve lives.
Joseph H. and Florence A. Roblee Foundation
Unspecified amount
Bayer Fund: Health & Wellness Grant Program
Full proposal due Sep 1, 2026
The Bayer Fund Health & Wellness Grant Program aims to support organizations that provide education and resources for patients and caregivers facing cancer and cardiovascular diseases. Grants focus on assisting communities, particularly the African American population, in managing these health issues. Funding covers educational services, disease awareness, and access to care, with all activities to commence post-funding decisions. Eligible organizations must hold a 501(c)(3) status and operate within 55 miles of Bayer sites.
Bayer Fund
US $75,000 - US $300,000
Pew Biomedical Scholars
Full proposal due Sep 3, 2026
The Pew Biomedical Scholars Program offers significant funding of $300,000 over four years to support early-career researchers in biomedical sciences. The program encourages innovative and impactful research that contributes to human health, requiring nomination from one of the 212 participating institutions. Candidates must hold a doctorate, run an independent lab as an assistant professor, and demonstrate exceptional promise. This program fosters collaboration and annual meetings for scholars to present their findings.
Pew Charitable Trusts
Up to US $25,000
Trio Foundation of St. Louis Grant
Applications due Sep 4, 2026
The Trio Foundation of St. Louis Grant aims to enhance community well-being and promote equity through its new funding framework. Established over two decades ago, the foundation focuses on empowering marginalized groups, particularly those facing discrimination based on race, gender, and socioeconomic status. The grant supports initiatives in women's economic empowerment, arts accessibility, and environmental justice, fostering authentic relationships with community partners to create lasting impact in the St. Louis region.
Trio Foundation of St. Louis
US $10,000 - US $50,000
Charless Foundation Grant
Applications due Sep 29, 2026
The Charless Foundation, part of the St. Louis Community Foundation, aims to support charitable organizations that promote the health and wellness of Missouri senior citizens, especially in South St. Louis City. Starting in 2025, grantmaking will focus on housing assistance, including home repairs and modifications for older adults. Additionally, funding for food banks will be available, capped at $10,000 per site. Grants can range from $10,000 to $50,000 annually, depending on the applicant's history with the foundation.
St Louis Community Foundation
Up to US $500,000 in in-kind support
Neighborhood Assistance Program
Applications due Oct 3, 2026
The Neighborhood Assistance Program (NAP), administered by the Missouri Department of Economic Development, provides tax credits to incentivize donations for community projects. Aimed at enhancing community service, education, and revitalization, NAP offers up to $16 million in credits, with a maximum of $500,000 per project. Eligible applicants include nonprofits and businesses, while donors can receive credits up to 70% for their contributions. Attend the virtual workshop on April 1, 2025, to learn more about applying.
Missouri Department of Economic Development
Unspecified amount
Dudley T. Dougherty Foundation Grant
Applications due Oct 31, 2026
The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.
Dudley T Dougherty Foundation Inc
US $5,000
Progress 64 Entrepreneurial Scholarship
Applications due Nov 1, 2026
The Progress 64 Entrepreneurial Scholarship, established by Progress 64 West, supports young entrepreneurs residing in St. Louis City, St. Louis County, or St. Charles County. This scholarship awards $5,000 to high school seniors for use at vocational schools, two-year, or four-year colleges. YouthBridge Community Foundation, dedicated to philanthropy and community support, facilitates this initiative, fostering a vibrant future for St. Louis youth.
Youthbridge Community Foundation
US $20,000
PLTW Engineering - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Engineering - New Program, supported by Burns & McDonnell, aims to empower U.S. students through STEM education. By offering at least one PLTW Engineering course in the 2026-2027 academic year, schools can enhance their curriculum and foster critical skills. This initiative not only increases access to valuable programs but also prepares students for future challenges in college and careers, ensuring they thrive in an evolving world.
Project Lead The Way Inc
US $10,000
PLTW Engineering - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Engineering - Program Expansion initiative aims to enhance STEM education by increasing access to Project Lead The Way (PLTW) programs in communities served by Burns & McDonnell. This partnership focuses on empowering students through real-world learning experiences, helping them develop essential skills for future careers. Starting in the 2026-2027 academic year, grants will support schools in expanding their existing PLTW Engineering programs to foster greater participation and engagement in STEM fields.
Project Lead The Way Inc
US $10,000
PLTW Gateway - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Gateway - New Program, in partnership with Burns & McDonnell, aims to enhance student engagement in STEM by providing teachers with essential resources and support. Starting in the 2026-2027 academic year, eligible schools can apply for grants to introduce and expand PLTW programs, fostering real-world skills through applied learning. This initiative targets schools with significant free and reduced-price lunch populations, promoting equity in education across various U.S. counties.
Project Lead The Way Inc
US $10,000
PLTW Gateway - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Gateway - Program Expansion initiative, led by Burns & McDonnell in partnership with Project Lead The Way (PLTW), aims to enhance STEM education by increasing access to PLTW programs for students in eligible communities. This program empowers students through real-world applied learning experiences, promoting essential skills for college and careers. Grants will support schools in expanding their existing PLTW Gateway programs starting in the 2026-2027 academic year, fostering a brighter future through education.
Project Lead The Way Inc
US $10,000
PLTW Launch - New Program (Lam Research)
Applications due Nov 7, 2026
The PLTW Launch - New Program initiative, sponsored by Burns & McDonnell, aims to enhance STEM education by providing grants to eligible schools within specific U.S. counties. Schools must implement PLTW modules over two academic years, ensuring access to real-world learning experiences for students, particularly those from low-income backgrounds. This program emphasizes the importance of empowering educators and fostering student engagement in STEM fields to prepare them for future careers.
Project Lead The Way Inc
US $5,000
PLTW Launch - Program Expansion (Lam Research)
Applications due Nov 7, 2026
The PLTW Launch - Program Expansion initiative by Burns & McDonnell aims to enhance access to STEM education in U.S. schools. This program focuses on empowering students by providing real-world learning experiences and essential skills. Grants will support schools in expanding PLTW programs during the 2026-2027 academic year, benefiting students from underserved communities. By fostering a deeper understanding of STEM, the initiative seeks to inspire the next generation of innovators and problem solvers.
Project Lead The Way Inc
Unspecified amount
Ameriprise Community Grants
Applications due Jan 15, 2027
Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.
Ameriprise Financial
Up to US $12,000
BJC Scholars Fund Scholarship
Applications due Apr 15, 2027
The BJC Scholars Fund Scholarship, backed by BJC HealthCare, aims to support high school seniors from specific Missouri and Illinois counties pursuing higher education. Eligible students can receive up to $12,000 per academic year, renewable for up to ten semesters. This initiative addresses community needs highlighted by the Ferguson Commission, promoting educational opportunities for youth in the regions served by BJC hospitals, which are known for their commitment to healthcare excellence.
The Scholarship Foundation of St. Louis
Unspecified amount
Marilyn and Morton Werner Egality Scholarship Fund
Applications due Apr 15, 2027
The Marilyn and Morton Werner Egality Scholarship Fund honors the legacy of its namesakes by supporting students committed to civic engagement and systemic change. Open to residents of the St. Louis metropolitan area, this scholarship prioritizes individuals with a proven record of leadership and community involvement. Award amounts reach up to $10,000 annually for graduate students and $6,000 for undergraduates, with funding available for up to five years. This initiative aims to empower the next generation of leaders in policy and public service.
The Scholarship Foundation of St. Louis
Up to US $15,000
New Era Scholarship
Applications due Apr 15, 2027
The New Era Scholarship, offered by The Scholarship Foundation of St. Louis, provides up to $12,000 annually for eligible students from select youth development agencies and high schools in the St. Louis area. This renewable scholarship supports those aiming to attend accredited colleges or technical schools in Missouri and select Illinois institutions. Applicants must demonstrate financial need and meet academic criteria, making this an essential opportunity for local high school seniors.
The Scholarship Foundation of St. Louis
Up to US $15,000
Nursing Scholarship Grants
Applications due Apr 15, 2027
The Deaconess Foundation offers Nursing Scholarship Grants aimed at supporting local students pursuing nursing degrees with demonstrated financial need. This program reflects the foundation's mission to enhance community health in Eastern Missouri and Southern Illinois. Grants are administered in partnership with the Scholarship Foundation of St. Louis and the St. Louis American Foundation. Eligible students must be working towards an accredited nursing degree and demonstrate significant financial need, among other criteria.
Deaconess Foundation
Unspecified amount
O'Reilly Automotive Foundation Grant
Applications due Apr 15, 2027
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
O'Reilly Automotive Foundation Inc
Up to US $4,500
Reverend Elie Collier Memorial Scholarship
Applications due Apr 15, 2027
The Reverend Elie Collier Memorial Scholarship honors the legacy of Rev. Elie Collier, who founded an auto body business and a church dedicated to community service. Established to support students from the St. Louis area, this scholarship offers grants up to $4,500 for vocational training. It aims to empower individuals through education, ensuring they have the tools needed for career success. The renewable grants can be utilized for tuition or essential tools required for accredited programs.
The Scholarship Foundation of St. Louis
Up to US $12,000
Saigh Foundation Bravo Grants
Applications due Apr 15, 2027
The Saigh Foundation Bravo Grants provide renewable scholarships of $12,000 per year to graduating high school seniors from the St. Louis metropolitan area who demonstrate significant financial need. These grants aim to support students who have overcome extraordinary challenges in their educational journey. Eligible applicants must have a minimum GPA of 2.0 and plan to attend an accredited nonprofit college or university. This initiative focuses on enhancing the quality of life for children and youth through education.
The Scholarship Foundation of St. Louis
Up to US $12,000
The Edward Jones Scholarship
Applications due Apr 15, 2027
The Edward Jones Scholarship, offered by The Scholarship Foundation of St. Louis, provides $12,000 annually to low-income students engaged with youth development agencies. This renewable scholarship aims to support those demonstrating financial need, with eligibility criteria including a minimum 2.0 GPA and residency in the St. Louis metropolitan area. The foundation envisions accessible educational opportunities for all, fulfilling its mission since 1920 to empower individuals through education and foster a strong democratic society.
The Scholarship Foundation of St. Louis
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Top Searched St. Louis city Grants for Nonprofits
Grant Insights : St. Louis city Grants for Nonprofits
Grant Availability
How common are grants in this category?
Uncommon — grants in this category are less prevalent than in others.
96 St. Louis city grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.
16 St. Louis city grants for nonprofits over $25K in average grant size
7 St. Louis city grants for nonprofits over $50K in average grant size
24 St. Louis city grants for nonprofits supporting general operating expenses
80 St. Louis city grants for nonprofits supporting programs / projects
900+ Grants on Instrumentl focused on STEM / STEAM Education
900+ Grants on Instrumentl focused on Education - K through 12
Grant Deadline Distribution
Over the past year, when are grant deadlines typically due for St. Louis city grants for Nonprofits?
Most grants are due in the fourth quarter.
Q1
21.1%
Q2
25.9%
Q3
23.5%
Q4
29.4%
Average Grant Size
What's the typical amount funded for Missouri?
Grants are most commonly $100,181.
$100,181
Total Number of Grants
What's the total number of grants in St. Louis city Grants for Nonprofits year over year?
In 2024, funders in Missouri awarded a total of 20,179 grants.
2022 39,922
2023 39,688
2024 20,179
Top Grant Focus Areas
Among all the St. Louis city Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.
1. Philanthropy, Voluntarism & Grantmaking Foundations
2. Education
3. Human Services
Funding Over Time
How is funding for St. Louis city Grants for Nonprofits changing over time?
Funding has increased by -61.86%.
2022 $4,698,402,122
2023
$5,287,874,816
12.55%
2024
$2,016,605,547
-61.86%
Missouri Counties That Receive the Most Funding
How does grant funding vary by county?
St Louis County, Jackson County, and St Louis City receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| St Louis County | $1,060,800,664 |
| Jackson County | $493,752,997 |
| St Louis City | $372,479,568 |
| Greene County | $134,480,889 |
| Cole County | $77,030,794 |
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