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Best Mississippi County Grants for Nonprofits in Missouri

Looking for grants for 501(c)(3) nonprofit organizations working in Mississippi County, Missouri? Find the perfect grant for your nonprofit on Instrumentl.

36

Available grants

$892.1K

Total funding

$13K

Median grant

36 grants
$892.1K total
$13K median

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Last updated: October 5, 2026. Next update: November 1, 2026.

AI summary from publicly available grant information

Unspecified amount

Creag Foundation Innovation Grants in Missouri

Rolling deadline
501(c)(3) nonprofits with at least one year of status and innovative approaches to social problems can apply for Creag Foundation support; funding can back new or reimagined human services programs. Organizations in Mississippi County, Missouri working creatively in areas like health, community development, or social services may be eligible to submit a letter of inquiry.
Creag Foundation

Up to US $300,000

Draper Richards Kaplan Early-Stage Impact Grants

Rolling deadline
Early-stage nonprofit and mission-driven for-profit social enterprises in Mississippi County, Missouri and beyond can apply for Draper Richards Kaplan Foundation’s support, with awards up to US $300,000 for scalable social and environmental solutions. Organizations should be post-pilot, under 10 years old, serving underserved communities, and positioned to rapidly expand their measurable impact.
Draper Richards Kaplan Foundation

Up to US $100,000

Global Impact Cash Grants

Rolling deadline
The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.
Cisco Systems Foundation

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More than US $100,000

Hearst Foundation Grants for Mississippi County Culture

Rolling deadline
Nonprofit cultural institutions serving U.S. audiences, including those reaching Mississippi County, Missouri, can seek more than US $100,000 to support arts and science programming. Grants from William Randolph Hearst Foundation help fund program, capital, and limited general or endowment support for museums, performing arts groups, arts education, artist training, and STEAM-focused initiatives.
William Randolph Hearst Foundation

More than US $100,000

Social Service Funding for Nonprofits from Hearst Foundation

Rolling deadline
Nonprofit 501(c)(3) organizations in Mississippi County, Missouri working on social services like poverty alleviation, housing, food access, job training, or youth development can apply for the Hearst Foundation’s Social Service Grant, with awards of more than US $100,000. Grants from William Randolph Hearst Foundation help U.S. nonprofits expand proven, scalable programs that strengthen families and promote economic independence.
William Randolph Hearst Foundation

Unspecified amount

Labcorp Charitable Foundation Community Grants in Missouri

Rolling deadline
Nonprofit 501(c)(3) organizations in Mississippi County, Missouri working in health, education, or community services can apply for grants supporting food pantries, healthcare access, STEM programs, and healthy lifestyle initiatives. With a mission to expand equitable care and education, Labcorp Charitable Foundation provides funding to U.S.-based charities serving underserved populations and local communities.
Labcorp Charitable Foundation

Unspecified amount

Michael & Susan Dell Foundation Grants for Education

Rolling deadline
Nonprofits and social enterprises supporting urban low-income children through education, health, or family economic stability projects in Mississippi County, Missouri may be eligible for more than US $50,000 in project or scale-up funding. Michael & Susan Dell Foundation supports work in the U.S., India, and South Africa that advances measurable outcomes for children and youth.
Michael & Susan Dell Foundation

Unspecified amount

Community and Education Funding for Nonprofits from Roche

Rolling deadline
Nonprofit organizations and accredited charities in Mississippi County, Missouri working on humanitarian, social, science education, community, environmental, or contemporary arts projects may be eligible for support. Grants from Roche help local programs that promote sustainable development, engage Roche expertise and employees, and are managed within the company’s affiliate framework in the same country.
La Roche, Inc.

Unspecified amount

Mississippi County Human Services Funding via Semnani Family Foundation

Rolling deadline
Nonprofit organizations providing health, education, or humanitarian services in Mississippi County, Missouri may be eligible for support that advances care for marginalized and vulnerable communities. Semnani Family Foundation supports global efforts in health care access, disaster relief, child and women’s services, literacy, and related human and social services, including work in the U.S.
Semnani Family Foundation

Unspecified amount

Sidney Stern Memorial Trust Grant

Rolling deadline
The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.
Sidney Stern Memorial Trust

Unspecified amount

Bank of America Support for Community Programs

Rolling deadline
Nonprofit 501(c)(3) organizations working on community development, basic needs, workforce readiness, arts, or related programs in Mississippi County, Missouri can seek sponsorship support through Bank of America Foundation. Bank of America Charitable Foundation offers regional U.S. sponsorships that may benefit local nonprofits advancing housing, jobs, hunger relief, culture, environment, and inclusion initiatives.
Bank Of America Charitable Foundation Inc

Unspecified amount

Mississippi County Community Funding via Robinson Foundation

Applications due Oct 15, 2026
Nonprofit 501(c)(3) organizations serving Mississippi County, Missouri and other Southern communities can seek funding for programs in education, poverty relief, health, disaster relief, families, veterans, animal welfare, conservation, and religious or spiritual work. Robinson Foundation supports single-year, program-focused projects from fiscally responsible organizations active for more than three years.
Robinson Foundation

Unspecified amount

Dudley T Dougherty Foundation Grants for Mississippi County Nonprofits

Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding in Mississippi County, Missouri may be eligible for this funding. Focused on community and environmental initiatives, the Dudley T Dougherty Foundation invites charitable organizations to apply for support that advances positive change and respects people, life, and the planet.
Dudley T Dougherty Foundation Inc

Unspecified amount

TJX Foundation Youth and Basic Needs Grants

Letter of inquiry due Oct 31, 2026
Grants supporting 501(c)(3) nonprofits providing basic needs, youth enrichment, workforce readiness, or domestic violence safety in Mississippi County, Missouri and other U.S. communities are available, if located within 15 miles of a TJX site. Grants from TJX Foundation help organizations serving vulnerable families and children build better futures through targeted programs rather than general operations.
The Tjx Foundation Inc

US $5,000 - US $10,000

Lawrence Foundation Grants for Mississippi County Nonprofits

Applications due Nov 1, 2026
Focused on environmental and human services work, 501(c)(3) nonprofits, public schools, and libraries in Mississippi County, Missouri can seek unrestricted program or operating support from the Lawrence Foundation; awards range from US $5,000 - US $10,000. U.S.-headquartered organizations working locally or globally on these priorities may benefit.
Lawrence Foundation

Up to US $4,000

Community Foundation of the Ozarks Economic Development Grants in Mississippi County

Applications due Nov 26, 2026
Nonprofit 501(c)(3) organizations and other IRS-approved entities serving Mississippi County, Missouri can apply for grants up to Up to US $4,000 to support economic services and development projects. Grants from Community Foundation of the Ozarks help strengthen quality of life across the Bootheel Regional Community Foundation service area, including Scott, Mississippi, New Madrid, Pemiscot, Dunklin and Stoddard counties.
Community Foundation of the Ozarks Inc.

US $250 - US $5,000

Spark Good: Strengthening Community - Local Grants

Applications due Nov 30, 2026
The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.
Wal-Mart Foundation

Unspecified amount

Ameriprise Financial Grants for Community Vitality

Applications due Jan 15, 2027
Nonprofit 501(c)(3) organizations addressing basic needs, community development, or volunteer-driven causes can apply for Ameriprise Financial grants; awards support hunger relief, shelter, adult self-sufficiency, and cultural enrichment. U.S.-based groups, including those serving Mississippi County, Missouri, must show measurable outcomes, financial stability, and alignment with Ameriprise focus areas and volunteer engagement priorities.
Ameriprise Financial

US $5,000 - US $20,000

Nordstrom Community Grant

Applications due Jan 31, 2027
The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.
Nordstrom

US $5,000 - US $25,000

Dr Scholl Foundation Grants for Mississippi County

Letter of inquiry due Feb 1, 2027
Dr Scholl Foundation provides Mississippi County, Missouri 501(c)(3) nonprofits with support for education, social services, health care, civic and cultural, and environmental projects. Eligible U.S. organizations can request US $5,000 - US $25,000 for one year of project funding, with one application per grant year and an online LOI required.
Dr Scholl Foundation

US $1,000

Community Foundation Support for Trade Education

Applications due Mar 9, 2027
Pittsfield High School graduates pursuing a technical trade, especially in the building trades, can receive $1,000 scholarships from Community Foundation of the Quincy Area, renewable for one additional year. Focused on vocational and trade education, this support may benefit students from Mississippi County, Missouri who meet the specific school and program criteria.
Community Foundation of the Quincy Area

More than US $50,000

Mississippi County Storytelling Funding via Jesse W Couch Foundation

Letter of inquiry due Mar 27, 2027
Nonprofit 501(c)(3) organizations and aligned for-profits in Mississippi County, Missouri can seek the Storytelling Grant to share the impact of their preservation, education, or wellness work. Grants from Jesse W Couch Charitable Foundation provide more than US $50,000 to help tell powerful stories about conservation, historic preservation, education, mental health, and related community programs.
Jesse W Couch Charitable Foundation

Unspecified amount

O'Reilly Automotive Foundation Grant

Applications due Apr 15, 2027
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
O'Reilly Automotive Foundation Inc

US $30,000 - US $350,000

True Inspiration Awards

Applications due May 1, 2027
The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.
Chick Fil A Foundation Inc

Up to US $3,000

Community Foundation of the Ozarks Grants for Inclusion

Applications due May 6, 2027
Mississippi County, Missouri nonprofits, government entities, school districts, and tax-exempt faith-based organizations can access funding through Community Foundation of the Ozarks to support diversity, equity, and inclusion efforts. Grants up to US $3,000 per year fund leadership development, equitable community and student engagement, and events that promote visible representations of belonging in local communities.
Community Foundation of the Ozarks Inc.

Unspecified amount

Mutual of America's Community Partnership Award

Applications due Jul 1, 2027
The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.
Mutual Of America Foundation

US $5,000 - US $250,000

Mississippi County Human Services Funding via Gupta Family Foundation

Applications due Jul 31, 2027
Nonprofit organizations addressing poverty, disability, social exclusion, or disaster relief that serve communities in Mississippi County, Missouri may be eligible for annual or multi-year support, with awards ranging from US $5,000 - US $250,000. With a mission to help disadvantaged people become self-reliant, Gupta Family Foundation focuses on smaller, non-sectarian organizations worldwide, typically 501(c)(3) entities or qualifying foreign nonprofits.
Gupta Family Foundation

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Mississippi County Grants for Nonprofits Highlights

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Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Missouri

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Mississippi County Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Mississippi County Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Mississippi County Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

Related Grants in Missouri

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