Best Grants for Nonprofit Healthcare Programs in Missouri

Missouri 501(c)(3) nonprofits serving the greater Kansas City area can seek $150,000 - $500,000 for healthcare, social services, education, arts, and Jewish community initiatives that expand services or improve outcomes for low-income, underserved residents. Focused on transformational change, the Marion and Henry Bloch Family Foundation supports special programs, capacity building, and capital projects rather than general operations.

Missouri 501(c)(3) nonprofits working on economic and workforce advancement, safe and affordable housing, or community arts and culture may be eligible for this program. Focused on community development, US Bancorp Foundation invites organizations in designated U.S. Bank communities to seek collaborative, high-impact funding, with priority for groups led by people of color; health-focused programs that fit these pillars may benefit.

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

Nonprofit and nongovernmental organizations using technology to tackle social challenges in Missouri can apply for Global Impact Cash Grants, with awards up to US $100,000 for innovative programs. Grants from Cisco Systems Foundation help organizations serving primarily economically underserved people advance crisis response, education access, economic empowerment, and climate resilience, which may benefit health-related community initiatives.

Nonprofit 501(c)(3) organizations in the greater Kansas City metro, including Missouri counties such as Jackson, Cass, Clay, and Platte, can apply for Hall Family Foundation’s grants to support community health, healthcare access, and related services. Programs in Missouri that advance equitable health, livable neighborhoods, and family well-being may be competitive.

U.S.-based 501(c)(3) cultural institutions with audited expenses over $2 million can apply for the Hearst Foundation’s culture grants to support arts and science programming, including in Missouri. Funding (often more than US $100,000) may support program, capital, or limited general/endowment needs, and health-related nonprofits with strong arts or STEM education components may be eligible.

Nonprofit healthcare and community organizations in Missouri can seek funding for health and welfare, education, or community initiatives that improve care access and well-being. Focused on health care access and delivery, the Labcorp Charitable Foundation invites U.S.-based 501(c)(3) groups to apply for support such as patient services, preventative healthcare, and related community programs.

The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.

Nonprofit 501(c)(3) organizations running health and medical assistance programs in Missouri and other Southern states can seek project support that creates tangible, meaningful impact. Robinson Foundation supports healthcare access alongside poverty relief, children and families, disaster relief, veterans, and related services for communities below the Mason-Dixon line; single-year funding only, no capital projects.

Nonprofit health and human service organizations in the Kansas City region of Missouri can receive unrestricted, one-year support for mission-driven programs through United Way of Greater Kansas City’s Impact 100. Funding supports work in areas like health care access and delivery, behavioral health, housing, food security, and related education and financial stability services.

Nonprofit 501(c)(3) organizations in Missouri located within 15 miles of a TJX store, distribution center, or office can seek funding for basic needs, youth education, workforce readiness, and domestic violence safety programs. The TJX Foundation supports vulnerable families and children through community-based services rather than capital campaigns, salaries, or general operating funds.

Nonprofit 501(c)(3) organizations, public schools, and libraries in Missouri seeking support for environmental or human services programs can apply for grants of US $5,000 - US $10,000. Grants from Lawrence Foundation help fund general operating or program expenses, issued as unrestricted support, and Missouri healthcare programs that fit these priorities may be eligible.

Nonprofit Partnership Grant ProgramJackson County, Missouri invites proposals from qualified non-profit organizations to receive competitive grant funding that directly serves and uplifts disadvantaged communities within the County. These funds are intended to support initiatives to promote equitable access to resources, improve quality of life, and address systemic disparities in areas such as housing, health, education, food insecurity, and community development.Jackson County recognizes that certain communities face historic and persistent barriers to opportunity. These barriers can stem from economic disinvestment, environmental hazards, limited access to healthcare, or systemic inequities in housing and employment. This grant program is designed to enable local organizations and agencies to address these challenges with innovative, impactful, and sustainable solutions.

Nonprofit 501(c)(3) organizations in Missouri addressing basic needs, community vitality, or volunteer-driven causes can apply for Ameriprise Community Grants to support hunger relief, shelter, economic development, arts access, and adult self-sufficiency programs. With a mission to strengthen communities, Ameriprise Financial provides U.S. nonprofits with funding that prioritizes measurable outcomes and Ameriprise employee or advisor volunteer engagement.

Nonprofit 501(c)(3) organizations addressing behavioral health and substance use disorders in Missouri and nationwide can apply for Elevance Health Foundation’s Behavioral Health Grant to expand treatment, prevention, and early intervention services. Grants support programs that increase access to MH/SUD treatment, reduce risks and harms, and lessen social isolation and loneliness among affected individuals.

Nonprofit 501(c)(3) organizations, school districts, and government entities supporting childcare for ages birth to five in rural Kansas or western Missouri can seek US $100,000 - US $500,000 to expand capacity, improve facilities, and increase affordability. Patterson Family Foundation supports projects serving its catchment communities; Missouri health-focused nonprofits offering childcare for working families may be eligible.

Missouri nonprofit healthcare programs, school districts, and government entities serving rural counties can access funding through the Patterson Family Foundation to develop, educate, license, recruit, or retain critical healthcare workers. Eligible organizations must operate within the foundation’s Kansas or western Missouri catchment and support thriving rural communities through healthcare workforce development initiatives.

Nonprofit 501(c)(3) organizations, school districts, and government entities expanding high school career and technical education programs in rural Missouri may be eligible for funding to modernize CTE offerings. With a mission to help rural communities thrive, Patterson Family Foundation supports projects that prepare students for high-demand industries and strengthen local workforces.

Missouri nonprofit 501(c)(3)s, school districts, and government entities improving rural education can access funding through the Patterson Family Foundation, with awards from US $25,000 - US $500,000. Projects in the foundation’s Kansas and western Missouri catchment that test new, potentially scalable ideas—especially project-based or experiential learning—may be eligible, including initiatives that strengthen rural health-related education pipelines.

Missouri nonprofit healthcare providers and other eligible 501(c)(3)s, school districts, and government entities can apply for Patterson Family Foundation’s Preventative Care Access Grant, awarding US $100,000 - US $500,000 to launch or expand care delivery models like telehealth, mobile health, and community paramedicine. Rural communities in the foundation’s Kansas and western Missouri catchment may benefit.

Nonprofit 501(c)(3) organizations, school districts, and government entities providing healthcare services in rural Kansas or western Missouri can apply for the Patterson Family Foundation’s Specialty Care Access Grant Program. Funding supports bringing specialty medical services—such as maternal care, oncology, dental, chronic disease, and mental or behavioral health—closer to rural communities, which may benefit Missouri nonprofit healthcare programs in eligible counties.

Nonprofit 501(c)(3) organizations, school districts, and government entities providing trades workforce training or upskilling can seek funding to support skilled trades, apprenticeships, and vocational education, including healthcare fields, in rural Missouri communities. Patterson Family Foundation supports projects serving its Kansas and western Missouri catchment, with potential multi-year support and limited capital and indirect cost funding.

Patterson Family Foundation

The Patterson Family Foundation, based in Kansas City, Missouri, is a family-led foundation that extends the legacy of Neal and Jeanne Patterson. The Foundation’s mission, “Working together to help rural communities thrive,” is carried forward through strategic grantmaking and other collaborative initiatives that serve rural counties across Kansas and western Missouri. 

At the Patterson Family Foundation, we believe that thriving rural communities aren’t just about the numbers—they’re about the people who choose to live there. A strong and engaged community is built on essentials like access to good jobs, quality healthcare, educational opportunities, and a sense of belonging. But keeping rural communities strong doesn’t happen on its own—it takes all of us working together. That’s why we focus on working with local leaders, businesses, and organizations to invest in the areas that matter most, ensuring that rural places don’t just get by but thrive for generations to come.

Community Needs Grant

We continue to invest in community-focused work through dedicated programs and initiatives that strengthen local leadership and support long-term community vitality. Our Community Engagement opportunities for the 2026 cycle are offered through targeted, collaborative efforts rather than an open call application process, allowing us to work closely with communities and organizations on high-impact, locally driven projects.

This opportunity supports projects that strengthen resident retention and encourage former residents to return by enhancing the spaces, services, and community assets that make rural places appealing to live, work, and build a future. Projects should help communities create environments where people feel connected, supported, and inspired to stay or come home. Applicants should plan to report on community participation, improvements to key spaces or assets, and early indicators of resident retention or increased engagement from returning residents. 

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

About Us

The Community Mental Health Fund makes grants to 501(c)(3) mental healthcare organizations. We are a public fund and services are audited. Care must meet standards set by the Board of Trustees and the State of Missouri. We also support multi-agency initiatives, including cultural competence and trauma-informed care. Services assist our community’s most vulnerable citizens. Abused children, battered women, and homeless families are among those we serve.

Our Mission

Our Mission is to support a network of quality mental health services for persons with mental illness that are equitably accessible and responsive to the varied and unique needs of Jackson County Missouri residents.

Mental Health Fund

Responding to Changing Mental Health Needs

We’re committed to identifying and pursuing partnerships with local agencies that provide mental health service to underserved Jackson County residents. Our new Community Grants target agencies that exemplify innovation and a forward-thinking mindset in their delivery of whole-person mental wellness services in these social determinants of health focus areas:

• Family - from expecting parents to early family life
• Life - housing and communities offering safe, supportive family environments
• Work - fair, supportive, and inclusive employment
• Aging - support for older adults’ community connectedness and access to care

Grant Funding Programs

General funding information

The Community Mental Health Fund invests in mental health services through partnerships with non-profit agencies that provide quality mental health care for persons with mental health concerns.

Through these partnerships, we strive to ensure that mental health services are equitably accessible and responsive to the varied and unique needs of Jackson County residents. Every year our funding supports over 25,000 residents who are without insurance and are in need of mental health care.

Grant funding programs

The Board of Trustees has authority to contract with established tax-exempt 501(c)(3) charitable corporations to: operate, supplement, maintain or deliver purchased services within: community mental health centers, mental health clinics or comprehensive mental health service providers. Funding is contractual and performance-based. Billing and treatment records are audited.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.