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Best Des Moines Grants for Nonprofits in Iowa

Looking for grants for 501(c)(3) nonprofit organizations working in Des Moines, Iowa? Find the perfect grant for your nonprofit on Instrumentl.

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Early Career Mini-Grant

Mensa Education And Research Foundation
Private
Countries
US $2,500

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Early Career Mini-Grant

The Mensa Foundation empowers emerging researchers through its Early Career Mini-Grant program.

Designed to support post-doctoral researchers and early career faculty, this grant funds innovative studies that advance our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Early Career Mini-Grant provides $2,500 to support post-doctoral researchers and faculty within five years of completing their doctoral degree. This grant is intended to promote groundbreaking studies that advance our understanding of intelligence and its applications in education and beyond.

Grant Components

Neuroscience Education Academic Success & Enrichment

Mensa Foundation: Copper Black Award

Mensa Education And Research Foundation
Private
Countries
US $1,000

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Cooper Black Award for Creativity

The Copper Black Award for Creative Achievement honors Mensa members whose innovative solutions and practical creativity have brought meaningful benefits to the world.

Details

The Copper Black Award annually recognizes Mensa International members who have demonstrated a specific creative achievement with practical value. This award honors innovations that have been implemented, at least in part, to benefit others.

Award Components

Humanities & Social Science STEM / STEAM Education

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $5,000 - US $10,000,000
The FY 2027 Continuation of Solicitation invites applications to support various program areas, including Advanced Scientific Computing, Basic Energy Sciences, Fusion Energy Sciences, and more. This annual open solicitation from the Department of Energy (DOE) allows research proposals throughout the fiscal year. Applications must align with SC's mission and can be submitted until September 30, 2027, or until a new solicitation is issued. Detailed submission processes are outlined in 10 C.F.R. part 605.
Energy Science Physics +1 more

Region 4 Small Business Transportation Technical Assistance Center (SBTTAC)

US Department of Transportation: Office of the Secretary (OST) Administration Secretariate
Federal Government
Alabama, Arkansas +7 more
Up to US $250,143
The Region 4 Small Business Transportation Technical Assistance Center (SBTTAC) aims to empower small businesses by providing essential technical assistance and business development support. Funded by the U.S. Department of Transportation, this initiative will facilitate access to capital resources, connect businesses with key transportation agencies, and ensure compliance with regulatory standards. The program is dedicated to minimizing barriers for small enterprises while fostering a robust support system in the transportation sector.
Entrepreneurship Economic Services & Development Business Development +1 more

Dairy Business Innovation Initiatives Program (DBI) Fiscal Year 2026

USDA: Agricultural Marketing Service (AMS)
Federal Government
United States
US $2,300,000 - US $3,450,000
The Dairy Business Innovation Initiatives Program (DBI) for Fiscal Year 2026, administered by the USDA's Agricultural Marketing Service, invites applications from existing initiatives to support the dairy industry. With approximately $12.65 million available, the program aims to diversify dairy markets, enhance farmer income, and promote regional milk production. Funding will prioritize equipment and infrastructure projects, which are vital for strengthening the capacity of dairy businesses and fostering innovation in processing and marketing.
Agriculture Agricultural Economics Business Development

WATER RESOURCES RESEARCH ACT PROGRAM NATIONAL COMPETITIVE GRANTS FY2026 (104g General)

US Department of the Interior: Geological Survey (USGS)
Federal Government
American Samoa, Guam +5 more
Up to US $120,000
The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.
Hydrology Freshwater Conservation Environmental Policy

Fiscal Year 2026 Wildlife Crossings Pilot Program

DOT Federal Highway Administration
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.
Land / Habitat Conservation Community / Public Safety Wildlife Health +1 more

The Science, Mathematics and Research for Transformation (SMART) Scholarship for Service Program Cooperative Agreement

US DOD: Office of the Secretary of Defense
Federal Government
American Samoa, Guam +4 more
US $1,300,000,000
The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.
Education - Higher Education Workforce Preparation & Job Readiness STEM / STEAM Education

Translational Research in Maternal and Pediatric Pharmacology and Therapeutics

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is set to renew a Notice of Funding Opportunity (NOFO) focused on advancing translational research in maternal and pediatric pharmacology. This initiative aims to enhance precision medicine by developing innovative tools and therapeutics for pregnant and lactating women, infants, and children. The goal is to improve the safety and efficacy of medications while ensuring effective patient-provider communications. Applications are not currently being solicited.
Pharmacology Children’s Health & Pediatrics Women's Health +1 more

Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.
Muscular Dystrophy

Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes (U01- Clinical Trials Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health is funding a groundbreaking project to enhance our understanding of Type 1 diabetes (T1D) through multimodal AI. This initiative aims to integrate diverse datasets to explore the interactions of biological processes in T1D development. By leveraging advanced AI models, the research will uncover critical insights, identify biomarkers, and pave the way for personalized medicine approaches, ultimately improving prevention and treatment strategies for this complex disease.
Diabetes

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.
HIV / AIDS

Modernizing Violent Death and Suicide Surveillance Using the National Violent Death Reporting System (NVDRS)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $966,085
The National Violent Death Reporting System (NVDRS) is a crucial surveillance initiative by the CDC aimed at understanding violent deaths and suicides. This funding opportunity supports state and local entities in modernizing NVDRS, enhancing data collection and reporting processes. Key activities include timely data updates, modernization assessments, and pilot projects for improved data systems. The goal is to create a sustainable national surveillance system that provides reliable data to inform public health actions and enhance violence and suicide prevention efforts.
Computer Science & Engineering Suicide Prevention Violence Prevention

Team and Club Support

The Usa Track & Field Foundation Inc
Private
United States
Unspecified amount

About USA Track & Field Foundation Inc

The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.

Mission: 

To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.Team and Club SupportThe USA Track & Field Foundation may be able to provide support to certain Elite Track & Field / Running clubs in the US.

Sports & Athletics

She Plus Foundation Grants

She Plus Foundation
Private
United States
Unspecified amount

About She+ Foundation The SHE+ Foundation, formerly known as The Patty Brisben Foundation for Women’s Sexual Health, was founded by Patty Brisben in 2005 after she recognized the profound need for a movement to address the too often ignored aspects of women’s sexual health. The SHE+ Foundation is committed to changing the narrative. We are here to advocate, educate, and fund research that advances the understanding and treatment for women’s sexual health, and improves quality of life for all women.Mission: Our mission is to advance women's sexual health and well-being through groundbreaking research, comprehensive education, and unwavering support. We strive to eradicate stigma, empower women with knowledge, and ensure equitable access to quality healthcare for all, regardless of socioeconomic status, race, or geography.About She+ Foundation GrantWe fund a wide range of projects that align with our mission to advance women's sexual health. This includes:

  • Research Studies: Clinical and academic research aimed at understanding and improving women's sexual health.
  • Educational Programs: Initiatives that provide education and awareness on topics related to women's sexual health.
  • Community Outreach: Programs that engage and support local communities, offering resources and support for women's sexual health.
  • Innovative Treatments: Development and implementation of new treatments and therapies for women's sexual health issues.

Women's Health

Geosciences Core Research: Atmospheric, Geospace, Earth and Ocean Sciences (GEO Core)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF Geosciences Core Research program funds innovative projects across atmospheric, geospace, earth, and ocean sciences. It encourages proposals that push the boundaries of knowledge in fundamental research, promoting interdisciplinary approaches. This initiative seeks transformative ideas that may not have immediate commercial applications but are crucial for advancing scientific understanding and addressing complex environmental challenges. Researchers are invited to explore various domains or integrate multiple disciplines to enhance our comprehension of the Earth and its systems.
Geoinformatics & Geospatial Sciences Earth Science Oceanography

Rural Communities Opioid Response Program - Overdose Response

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $300,000
The Rural Communities Opioid Response Program - Overdose Response aims to enhance healthcare access in rural areas by addressing urgent needs related to substance use disorder services. This initiative focuses on reducing overdose risks through targeted interventions and support, ensuring that rural communities receive necessary assistance. Funded by the Health Resources and Services Administration, this program is crucial for mitigating the opioid crisis in underserved regions, improving health outcomes, and promoting overall community well-being.
Community Services Rural Development Addiction & Substance Use Disorders +1 more

Rural Communities Opioid Response Program - Child and Adolescent Behavioral Health

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $1,000,000
The Rural Communities Opioid Response Program focuses on enhancing behavioral health care services for children and adolescents in rural areas. By providing essential funding, this initiative aims to tackle mental health and substance use disorders, ensuring that young individuals receive the support they need. The program, administered by the Health Resources and Services Administration, is crucial in addressing the unique challenges faced by rural communities, promoting healthier outcomes for future generations.
Community Services Addiction & Substance Use Disorders Drug Use Disorder

WEF Professional Development Grant

Wallingford Education Foundation (WEF)
Association/Society
United States
US $1,000 - US $2,000

Wallingford Education Foundation

Our Mission

The Wallingford Education Foundation is a non-profit, community-based partnership supporting educational innovation and excellence in our town.

Our Vision

The Wallingford Education Foundation empowers ideas and enhances educational experiences for students, educators and community members. It provides financial support outside the education budget that is aligned with the goals and focus areas of the school district’s strategic plan.

Professional Development Grant

Transformative impacts often result from staff members who choose to attend professional development programs. Typically, these opportunities are funded through the town’s annual school budget. However, the district may not be financially able to meet each request. Through the Professional Development Grant program, the Wallingford Education Foundation (WEF) provides additional funding for employees of Wallingford Public Schools to attend conferences hosted outside the district.

The Professional Grant program offers paired grants of $1,000 each for two Wallingford Public Schools staff members to attend the same professional development opportunity together OR single grants of up to $2,000 for an individual to attend a conference alone. Multiple grants are awarded yearly.

Teacher Development & Training

Spirit of Blue Safety Grant

Spirit of Blue Foundation
Private
U.S. Territories, United States
Unspecified amount

About Spirit of Blue

Our Vision

To become the nation’s leading supplemental provider of law enforcement safety equipment and training across the county.

Our Mission

Spirit of Blue is dedicated to the enhancement of officer safety throughout the law enforcement community by fulfilling unfunded safety equipment and training needs.

Safety Grant Program

Spirit of Blue’s primary initiative is the granting of safety equipment and training to municipal, county and state law enforcement agencies in an effort to protect their sworn personnel. 

Most grants are 100% funded, meaning that no match is required. In the majority of cases, Spirit of Blue conducts the procurement of the goods or services being granted so that the recipient agency isn’t burdened with having to negotiate prices, place orders or track delivery. Rarely, if ever, does Spirit of Blue provide cash awards. Once selected, Spirit of Blue will provide the recipient agency with an official grant award letter outlining everything that is contained in the award. The recipient agency must gain acceptance of the grant, whether on the authority of their agency head or by working with their local governing authority as their policy may dictate. There are no reporting requirements after the award of the grant, but agencies are asked to submit a photo to be used in the announcement of their grant.

Grant Application

The Spirit of Blue Safety Grant Program is designed to award equipment, or in some cases training, that will protect officers serving on duty. You should only request items that you can articulate will have a positive impact on officer safety.

Police & Law Enforcement Community / Public Safety

Al Lucas Memorial Scholarship Fund

Community Foundation of Central Georgia
Private
United States
US $1,000

About

The Community Foundation of Central Georgia was founded in 1993 by a group of citizens interested in encouraging philanthropy and strengthening communities.

The Foundation provides donors a simple, powerful, and highly personal approach to giving. Through their funds, CFCG donors support the causes and organizations that they care about, which enhances the quality of life for the people of Central Georgia.

Our vision is a Central Georgia where philanthropy thrives, communities are strong, and citizens work toward common goals.

Al Lucas Memorial Scholarship Fund

Albert James “Big Luke” Lucas was born September 1, 1978, to David E. and Elaine H. Lucas. He passed away on April 10, 2005, from a spinal cord injury he suffered during a Los Angeles Avengers arena football game. He was married to De’Shonda, and had a daughter, Mariah.

Al was a native of Macon, Georgia, graduating from Northeast High School in 1996. Following graduation, he attended Troy State University on a full athletic scholarship, and shined as a defensive lineman for the Trojans. Throughout college Al studied hard and cherished his time on the field and in 2000 was awarded the distinguished Buck Buchanan Award as the top defensive player in Division 1-AA. He was also an outstanding member of Omega Psi Phi Fraternity, Inc. He graduated in 2000 with a Bachelor of Science degree in Criminal Justice. Al went on to join the National Football League, signing as a free agent with the Pittsburgh Steelers and later playing for the Carolina Panthers. Later he joined the Arena Football League, playing for the Tampa Bay Storm, and finally the Los Angeles Avengers.

Al was a strong athlete with a heart of gold who believed in giving back to the community that supported him over the years. He especially loved working with children and served as a substitute teacher and coach at Northeast High School during the off-season. He was a member of Steward Chapel A.M.E. Church where he first learned the responsibility and power of tithing.

Al Lucas exemplified the characteristics of a scholar-athlete. He loved athletics, but knew his studies came first. He served his community and the Lord. He expected the best of himself and others. He excelled on the football field and in life. Recipients of the Al Lucas Memorial Scholarship will reflect Al’s ideals and carry on his legacy of excellence.

Purpose

  • To honor the memory of Al Lucas by providing college scholarships to scholar athletes in Al’s hometown of Macon, Georgia.

Awards

  • Amount of Award: $1,000, non-renewable.
  • Number of Awards: 7 per year. Two awards will be given to scholar-athletes graduating from Northeast High School, Al’s alma mater. One winner shall be female and one male. The other five awards will be given to student-athletes from each of the other five Bibb County public high schools. One will be awarded at each school.
Education - Higher Education Education - High School Academic Scholarship Programs

Clifton-Whitehead Scholarship Fund

Community Foundation of Central Georgia
Private
United States
US $1,000
The Clifton-Whitehead Scholarship Fund, established by Edward S. Whitehead, Jr. in honor of his relatives, supports deserving students in Middle Georgia, particularly in Bibb County. This fund aims to assist students of good character facing financial challenges in obtaining a college education. Annually, approximately 12 awards of around $1,000 are granted. Eligible recipients must maintain a minimum GPA and can renew the scholarship for up to four years, provided they meet the established criteria.
Education - Higher Education Education - High School Academic Scholarship Programs

Christine Riggins Shepherd Scholarship Fund

Community Foundation of Central Georgia
Private
United States
Unspecified amount
The Christine Riggins Shepherd Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support students from Lamar, Pike, Monroe, Upson, or Spalding counties attending Georgia Southern University. With at least one award given annually, the scholarship amount varies. Recipients can renew their scholarships for up to four years if they maintain eligibility. Preference is given to applicants from Lamar County, promoting educational opportunities for local students.
Education - Higher Education Education - High School Academic Scholarship Programs

Career Women’s Network Scholarship Fund

Community Foundation of Central Georgia
Private
United States
Unspecified amount
The Career Women’s Network Scholarship Fund, established by the Community Foundation of Central Georgia, empowers non-traditional female students aged 25 and older to pursue higher education. This scholarship promotes leadership and personal development for women in the community, offering varying amounts each year. Recipients may renew their awards for up to four years, contingent on meeting eligibility criteria. The fund honors Katherine Walters, who valued education and aimed to assist women in achieving their academic goals.
Education - Higher Education Academic Scholarship Programs

Assisting Specialty Crop Exports: Low Oxygen Storage and Packaging Systems for U.S. Tree Nuts with Phytosanitary Traceability

Foreign Agricultural Service
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The Assisting Specialty Crop Exports initiative aims to enhance U.S. specialty crop market access by developing low-oxygen storage and packaging systems for tree nuts. By addressing phytosanitary requirements and pest control, the initiative supports producers in maintaining product quality while complying with international standards. This funding opportunity from the Foreign Agricultural Service encourages innovative solutions that can improve export processes and reduce reliance on costly fumigation methods, ultimately benefiting U.S. agribusiness and ensuring competitiveness in global markets.
Agricultural Crops Insect Pest Control Agricultural Pest Management +1 more

Father John Foundation Grant

FATHER JOHN FOUNDATION
Private
United States
Unspecified amount
About Father John Foundation GrantIn 1997 Monsignor John P. Hourihan established this perpetual charitable foundation for the purpose of funding care for the homeless and people with disabilities, especially the deaf and hard of hearing. The purpose of the Foundation is to financially assist churches and other non-profit organizations, that do not take more than insubstantial government funding, in administering their programs. Our giving focus is broad and considers programs that are: religious, educational, rehabilitational, social, and/or vocational. A priority is given to the deaf and homeless. All funding is given regardless of nationality, race or religion. The Foundation will continue its dedication to raising and distributing grants to be used by charities devoted to providing care and services to the homeless and disabled.
Education Homelessness Services Hearing Impairment Care & Services +1 more

ABF Next Generation Research Grants - Stroke

American Brain Foundation
Private
United States
Up to US $150,000

American Brain Foundation

The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.

Next Generation Research Grants

The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.

Lawrence M. Brass, MD Clinical Research Training Scholarship in Stroke

This award aims to recognize the importance of good clinical research and to encourage early career investigators in clinical studies related to stroke, vascular neurology, and neurocritical care.

For the purpose of this scholarship, research is defined as “patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance diagnosis of neurological disease. These areas of research include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health services and outcomes research.” Disease-related studies not directly involving humans or human tissue are also encouraged if the primary goal is the development of therapies, diagnostic tests, or other tools to prevent or mitigate neurological diseases.

Stroke Neuroscience Neurological Diseases & Disorders

Des Moines Grants for Nonprofits Highlights

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Last updated: October 5, 2026. Next update: November 1, 2026.

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